Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP00582
DateThu Jan 5 10:56:46 GMT 2012
Unique Job ID4fbef07baa1be727

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1cmwA_
Top template information
PDB header:transferase
Chain: A: PDB Molecule:protein (dna polymerase i);
PDBTitle: crystal structure of taq dna-polymerase shows a new2 orientation for the structure-specific nuclease domain
Confidence and coverage
Confidence:100.0% Coverage: 88%
814 residues ( 88% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MVQIPQNPLILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLNMLRSLIMQYKPTHAAV
Secondary structure 
























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Disorder  ??????






















??




























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   .........70.........80.........90.........100.........110.........120
Sequence  VFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHAMVKAMGLPLLAVSGVEADDVIGT
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?





???
???



































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   .........130.........140.........150.........160.........170.........180
Sequence  LAREAEKAGRPVLISTGDKDMAQLVTPNITLINTMTNTILGPEEVVNKYGVPPELIIDFL
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?






















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   .........190.........200.........210.........220.........230.........240
Sequence  ALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYAEPEKIAGLSFRGAKTMAAKLEQNK
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?????????








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   .........250.........260.........270.........280.........290.........300
Sequence  EVAYLSYQLATIKTDVELELTCEQLEVQQPAAEELLGLFKKYEFKRWTADVEAGKWLQAK
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???





???????
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   .........310.........320.........330.........340.........350.........360
Sequence  GAKPAAKPQETSVADEAPEVTATVISYDNYVTILDEETLKAWIAKLEKAPVFAFDTETDS
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Disorder  ?????????????????????
??



































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   .........370.........380.........390.........400.........410.........420
Sequence  LDNISANLVGLSFAIEPGVAAYIPVAHDYLDAPDQISRERALELLKPLLEDEKALKVGQN
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   .........430.........440.........450.........460.........470.........480
Sequence  LKYDRGILANYGIELRGIAFDTMLESYILNSVAGRHDMDSLAERWLKHKTITFEEIAGKG
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   .........490.........500.........510.........520.........530.........540
Sequence  KNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWPDLQKHKGPLNVFENIEMPLVPVLSRI
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   .........550.........560.........570.........580.........590.........600
Sequence  ERNGVKIDPKVLHNHSEELTLRLAELEKKAHEIAGEEFNLSSTKQLQTILFEKQGIKPLK
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???
?
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   .........610.........620.........630.........640.........650.........660
Sequence  KTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAKLKSTYTDKLPLMINPKTGRVHTSYH
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   .........670.........680.........690.........700.........710.........720
Sequence  QAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFIAPEDYVIVSADYSQIELRIMAHLSRD
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?

??


































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   .........730.........740.........750.........760.........770.........780
Sequence  KGLLTAFAEGKDIHRATAAEVFGLPLETVTSEQRRSAKAINFGLIYGMSAFGLARQLNIP
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   .........790.........800.........810.........820.........830.........840
Sequence  RKEAQKYMDLYFERYPGVLEYMERTRAQAKEQGYVETLDGRRLYLPDIKSSNGARRAAAE
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?????????


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   .........850.........860.........870.........880.........890.........900
Sequence  RAAINAPMQGTAADIIKRAMIAVDAWLQAEQPRVRMIMQVHDELVFEVHKDDVDAVAKQI
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   .........910.........920........
Sequence  HQLMENCTRLDVPLLVEVGSGENWDQAH
Secondary structure 










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Disorder 

























??
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1cmw chain A

3D model

Region: 5 - 928
Aligned: 814
Modelled: 836
Confidence: 100.0%
Identity: 41%
PDB header:transferase
Chain: A: PDB Molecule:protein (dna polymerase i);
PDBTitle: crystal structure of taq dna-polymerase shows a new2 orientation for the structure-specific nuclease domain

Phyre2

PDB 2kzz chain A

3D model

Region: 325 - 928
Aligned: 600
Modelled: 604
Confidence: 100.0%
Identity: 100%
PDB header:transferase/dna
Chain: A: PDB Molecule:protein (dna polymerase i);
PDBTitle: klenow fragment with normal substrate and zinc only

Phyre2

PDB 1njz chain A

3D model

Region: 326 - 927
Aligned: 578
Modelled: 590
Confidence: 100.0%
Identity: 40%
PDB header:transferase/dna
Chain: A: PDB Molecule:dna polymerase i;
PDBTitle: cytosine-thymine mismatch at the polymerase active site

Phyre2

PDB 4ktq chain A

3D model

Region: 356 - 928
Aligned: 536
Modelled: 548
Confidence: 100.0%
Identity: 43%
PDB header:transferase/dna
Chain: A: PDB Molecule:protein (large fragment of dna polymerase i);
PDBTitle: binary complex of the large fragment of dna polymerase i2 from t. aquaticus bound to a primer/template dna

Phyre2

PDB 1tk0 chain A

3D model

Region: 352 - 928
Aligned: 553
Modelled: 565
Confidence: 100.0%
Identity: 26%
PDB header:transferase/electron transport/dna
Chain: A: PDB Molecule:dna polymerase;
PDBTitle: t7 dna polymerase ternary complex with 8 oxo guanosine and2 ddctp at the insertion site

Phyre2

PDB 1qtm chain A domain 2

3D model

Region: 519 - 927
Aligned: 407
Modelled: 409
Confidence: 100.0%
Identity: 49%
Fold: DNA/RNA polymerases
Superfamily: DNA/RNA polymerases
Family: DNA polymerase I

Phyre2

PDB 2hhv chain A domain 2

3D model

Region: 522 - 927
Aligned: 405
Modelled: 406
Confidence: 100.0%
Identity: 49%
Fold: DNA/RNA polymerases
Superfamily: DNA/RNA polymerases
Family: DNA polymerase I

Phyre2

PDB 1kfs chain A domain 2

3D model

Region: 519 - 928
Aligned: 406
Modelled: 410
Confidence: 100.0%
Identity: 100%
Fold: DNA/RNA polymerases
Superfamily: DNA/RNA polymerases
Family: DNA polymerase I

Phyre2

PDB 1x9m chain A domain 2

3D model

Region: 526 - 928
Aligned: 387
Modelled: 403
Confidence: 100.0%
Identity: 27%
Fold: DNA/RNA polymerases
Superfamily: DNA/RNA polymerases
Family: DNA polymerase I

Phyre2

PDB 2ihn chain A

3D model

Region: 6 - 293
Aligned: 275
Modelled: 288
Confidence: 100.0%
Identity: 15%
PDB header:hydrolase/dna
Chain: A: PDB Molecule:ribonuclease h;
PDBTitle: co-crystal of bacteriophage t4 rnase h with a fork dna2 substrate

Phyre2

PDB 1ut8 chain B

3D model

Region: 7 - 282
Aligned: 255
Modelled: 261
Confidence: 100.0%
Identity: 22%
PDB header:hydrolase
Chain: B: PDB Molecule:exodeoxyribonuclease;
PDBTitle: divalent metal ions (zinc) bound to t5 5'-exonuclease

Phyre2

PDB 1cmw chain A domain 2

3D model

Region: 5 - 170
Aligned: 164
Modelled: 166
Confidence: 100.0%
Identity: 40%
Fold: PIN domain-like
Superfamily: PIN domain-like
Family: 5' to 3' exonuclease catalytic domain

Phyre2

PDB 1rxv chain A

3D model

Region: 6 - 286
Aligned: 250
Modelled: 262
Confidence: 100.0%
Identity: 22%
PDB header:hydrolase/dna
Chain: A: PDB Molecule:flap structure-specific endonuclease;
PDBTitle: crystal structure of a. fulgidus fen-1 bound to dna

Phyre2

PDB 1a77 chain A

3D model

Region: 6 - 293
Aligned: 254
Modelled: 261
Confidence: 100.0%
Identity: 22%
PDB header:5'-3' exo/endo nuclease
Chain: A: PDB Molecule:flap endonuclease-1 protein;
PDBTitle: flap endonuclease-1 from methanococcus jannaschii

Phyre2

PDB 3q8l chain A

3D model

Region: 6 - 295
Aligned: 267
Modelled: 279
Confidence: 100.0%
Identity: 22%
PDB header:hydrolase/dna
Chain: A: PDB Molecule:flap endonuclease 1;
PDBTitle: crystal structure of human flap endonuclease fen1 (wt) in complex with2 substrate 5'-flap dna, sm3+, and k+

Phyre2

PDB 1b43 chain A

3D model

Region: 6 - 292
Aligned: 255
Modelled: 269
Confidence: 100.0%
Identity: 22%
PDB header:transferase
Chain: A: PDB Molecule:protein (fen-1);
PDBTitle: fen-1 from p. furiosus

Phyre2

PDB 3ory chain A

3D model

Region: 6 - 294
Aligned: 261
Modelled: 267
Confidence: 100.0%
Identity: 20%
PDB header:hydrolase
Chain: A: PDB Molecule:flap endonuclease 1;
PDBTitle: crystal structure of flap endonuclease 1 from hyperthermophilic2 archaeon desulfurococcus amylolyticus

Phyre2

PDB 2izo chain A

3D model

Region: 6 - 286
Aligned: 215
Modelled: 223
Confidence: 100.0%
Identity: 22%
PDB header:hydrolase
Chain: A: PDB Molecule:flap structure-specific endonuclease;
PDBTitle: structure of an archaeal pcna1-pcna2-fen1 complex

Phyre2

PDB 1yt3 chain A

3D model

Region: 329 - 755
Aligned: 367
Modelled: 393
Confidence: 100.0%
Identity: 17%
PDB header:hydrolase,translation
Chain: A: PDB Molecule:ribonuclease d;
PDBTitle: crystal structure of escherichia coli rnase d, an2 exoribonuclease involved in structured rna processing

Phyre2

PDB 1xo1 chain A domain 2

3D model

Region: 6 - 170
Aligned: 140
Modelled: 150
Confidence: 100.0%
Identity: 24%
Fold: PIN domain-like
Superfamily: PIN domain-like
Family: 5' to 3' exonuclease catalytic domain

Phyre2
1

c1cmwA_
2

c2kzzA_
3

c1njzA_
4

c4ktqA_
5

c1tk0A_
6

d1qtma2
7

d2hhva2
8

d1kfsa2
9

d1x9ma2
10

c2ihnA_
11

c1ut8B_
12

d1cmwa2
13

c1rxvA_
14

c1a77A_
15

c3q8lA_
16

c1b43A_
17

c3oryA_
18

c2izoA_
19

c1yt3A_
20

d1xo1a2
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1cmwA_



100.0 41 PDB header:transferase
Chain: A: PDB Molecule:protein (dna polymerase i);
PDBTitle: crystal structure of taq dna-polymerase shows a new2 orientation for the structure-specific nuclease domain
2c2kzzA_



100.0 100 PDB header:transferase/dna
Chain: A: PDB Molecule:protein (dna polymerase i);
PDBTitle: klenow fragment with normal substrate and zinc only
3c1njzA_



100.0 40 PDB header:transferase/dna
Chain: A: PDB Molecule:dna polymerase i;
PDBTitle: cytosine-thymine mismatch at the polymerase active site
4c4ktqA_



100.0 43 PDB header:transferase/dna
Chain: A: PDB Molecule:protein (large fragment of dna polymerase i);
PDBTitle: binary complex of the large fragment of dna polymerase i2 from t. aquaticus bound to a primer/template dna
5c1tk0A_



100.0 26 PDB header:transferase/electron transport/dna
Chain: A: PDB Molecule:dna polymerase;
PDBTitle: t7 dna polymerase ternary complex with 8 oxo guanosine and2 ddctp at the insertion site
6d1qtma2



100.0 49 Fold:DNA/RNA polymerases
Superfamily:DNA/RNA polymerases
Family:DNA polymerase I
7d2hhva2



100.0 49 Fold:DNA/RNA polymerases
Superfamily:DNA/RNA polymerases
Family:DNA polymerase I
8d1kfsa2



100.0 100 Fold:DNA/RNA polymerases
Superfamily:DNA/RNA polymerases
Family:DNA polymerase I
9d1x9ma2



100.0 27 Fold:DNA/RNA polymerases
Superfamily:DNA/RNA polymerases
Family:DNA polymerase I
10c2ihnA_



100.0 15 PDB header:hydrolase/dna
Chain: A: PDB Molecule:ribonuclease h;
PDBTitle: co-crystal of bacteriophage t4 rnase h with a fork dna2 substrate
11c1ut8B_



100.0 22 PDB header:hydrolase
Chain: B: PDB Molecule:exodeoxyribonuclease;
PDBTitle: divalent metal ions (zinc) bound to t5 5'-exonuclease
12d1cmwa2



100.0 40 Fold:PIN domain-like
Superfamily:PIN domain-like
Family:5' to 3' exonuclease catalytic domain
13c1rxvA_



100.0 22 PDB header:hydrolase/dna
Chain: A: PDB Molecule:flap structure-specific endonuclease;
PDBTitle: crystal structure of a. fulgidus fen-1 bound to dna
14c1a77A_



100.0 22 PDB header:5'-3' exo/endo nuclease
Chain: A: PDB Molecule:flap endonuclease-1 protein;
PDBTitle: flap endonuclease-1 from methanococcus jannaschii
15c3q8lA_



100.0 22 PDB header:hydrolase/dna
Chain: A: PDB Molecule:flap endonuclease 1;
PDBTitle: crystal structure of human flap endonuclease fen1 (wt) in complex with2 substrate 5'-flap dna, sm3+, and k+
16c1b43A_



100.0 22 PDB header:transferase
Chain: A: PDB Molecule:protein (fen-1);
PDBTitle: fen-1 from p. furiosus
17c3oryA_



100.0 20 PDB header:hydrolase
Chain: A: PDB Molecule:flap endonuclease 1;
PDBTitle: crystal structure of flap endonuclease 1 from hyperthermophilic2 archaeon desulfurococcus amylolyticus
18c2izoA_



100.0 22 PDB header:hydrolase
Chain: A: PDB Molecule:flap structure-specific endonuclease;
PDBTitle: structure of an archaeal pcna1-pcna2-fen1 complex
19c1yt3A_



100.0 17 PDB header:hydrolase,translation
Chain: A: PDB Molecule:ribonuclease d;
PDBTitle: crystal structure of escherichia coli rnase d, an2 exoribonuclease involved in structured rna processing
20d1xo1a2



100.0 24 Fold:PIN domain-like
Superfamily:PIN domain-like
Family:5' to 3' exonuclease catalytic domain
21c1ul1Y_



not modelled 100.0 19 PDB header:hydrolase/dna binding protein
Chain: Y: PDB Molecule:flap endonuclease-1;
PDBTitle: crystal structure of the human fen1-pcna complex
22d1tfra2



not modelled 100.0 18 Fold:PIN domain-like
Superfamily:PIN domain-like
Family:5' to 3' exonuclease catalytic domain
23c3qeaZ_



not modelled 100.0 19 PDB header:hydrolase/dna
Chain: Z: PDB Molecule:exonuclease 1;
PDBTitle: crystal structure of human exonuclease 1 exo1 (wt) in complex with dna2 (complex ii)
24d1kfsa1



not modelled 100.0 100 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
25d1cmwa1



not modelled 100.0 33 Fold:SAM domain-like
Superfamily:5' to 3' exonuclease, C-terminal subdomain
Family:5' to 3' exonuclease, C-terminal subdomain
26d2hhva1



not modelled 100.0 23 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
27c3ikmD_



not modelled 99.9 25 PDB header:transferase
Chain: D: PDB Molecule:dna polymerase subunit gamma-1;
PDBTitle: crystal structure of human mitochondrial dna polymerase2 holoenzyme
28d1yt3a3



not modelled 99.9 20 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
29d2hbka2



not modelled 99.9 17 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
30c2hbkA_



not modelled 99.9 16 PDB header:hydrolase, gene regulation
Chain: A: PDB Molecule:exosome complex exonuclease rrp6;
PDBTitle: structure of the yeast nuclear exosome component, rrp6p,2 reveals an interplay between the active site and the hrdc3 domain; protein in complex with mn
31d1xo1a1



not modelled 99.9 22 Fold:SAM domain-like
Superfamily:5' to 3' exonuclease, C-terminal subdomain
Family:5' to 3' exonuclease, C-terminal subdomain
32c3cymA_



not modelled 99.8 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein bad_0989;
PDBTitle: crystal structure of protein bad_0989 from bifidobacterium2 adolescentis
33c3sahA_



not modelled 99.8 17 PDB header:hydrolase
Chain: A: PDB Molecule:exosome component 10;
PDBTitle: crystal structure of the human rrp6 catalytic domain with y436a2 mutation in the catalytic site
34c2e6mA_



not modelled 99.8 17 PDB header:hydrolase
Chain: A: PDB Molecule:werner syndrome atp-dependent helicase homolog;
PDBTitle: structure of mouse werner exonuclease domain
35d1a77a1



not modelled 99.7 24 Fold:SAM domain-like
Superfamily:5' to 3' exonuclease, C-terminal subdomain
Family:5' to 3' exonuclease, C-terminal subdomain
36d1ul1x1



not modelled 99.7 20 Fold:SAM domain-like
Superfamily:5' to 3' exonuclease, C-terminal subdomain
Family:5' to 3' exonuclease, C-terminal subdomain
37d1rxwa1



not modelled 99.7 21 Fold:SAM domain-like
Superfamily:5' to 3' exonuclease, C-terminal subdomain
Family:5' to 3' exonuclease, C-terminal subdomain
38d1b43a1



not modelled 99.7 18 Fold:SAM domain-like
Superfamily:5' to 3' exonuclease, C-terminal subdomain
Family:5' to 3' exonuclease, C-terminal subdomain
39d1mc8a1



not modelled 99.6 19 Fold:SAM domain-like
Superfamily:5' to 3' exonuclease, C-terminal subdomain
Family:5' to 3' exonuclease, C-terminal subdomain
40d1rxwa2



not modelled 99.6 24 Fold:PIN domain-like
Superfamily:PIN domain-like
Family:5' to 3' exonuclease catalytic domain
41d1a77a2



not modelled 99.6 22 Fold:PIN domain-like
Superfamily:PIN domain-like
Family:5' to 3' exonuclease catalytic domain
42d1b43a2



not modelled 99.5 23 Fold:PIN domain-like
Superfamily:PIN domain-like
Family:5' to 3' exonuclease catalytic domain
43d1mc8a2



not modelled 99.5 26 Fold:PIN domain-like
Superfamily:PIN domain-like
Family:5' to 3' exonuclease catalytic domain
44d1ul1x2



not modelled 99.5 16 Fold:PIN domain-like
Superfamily:PIN domain-like
Family:5' to 3' exonuclease catalytic domain
45d1vk0a_



not modelled 99.4 16 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
46d1x9ma1



not modelled 99.0 21 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
47d2qxfa1



not modelled 98.8 16 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
48d1wn7a1



not modelled 98.7 25 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
49c2is3B_



not modelled 98.7 11 PDB header:hydrolase
Chain: B: PDB Molecule:ribonuclease t;
PDBTitle: crystal structure of escherichia coli rnase t
50d1y97a1



not modelled 98.7 16 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
51d1tgoa1



not modelled 98.7 24 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
52d1qhta1



not modelled 98.7 23 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
53d1uoca_



not modelled 98.7 16 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:CAF1-like ribonuclease
54c2p1jB_



not modelled 98.6 23 PDB header:transferase
Chain: B: PDB Molecule:dna polymerase iii polc-type;
PDBTitle: crystal structure of a polc-type dna polymerase iii2 exonuclease domain from thermotoga maritima
55d1d5aa1



not modelled 98.6 22 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
56d2f96a1



not modelled 98.5 16 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
57d1wlja_



not modelled 98.5 22 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
58d2d5ra1



not modelled 98.5 22 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:CAF1-like ribonuclease
59c3u6fA_



not modelled 98.5 16 PDB header:hydrolase/dna
Chain: A: PDB Molecule:three prime repair exonuclease 1;
PDBTitle: mouse trex1 d200n mutant
60d1s5ja1



not modelled 98.5 23 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
61d2guia1



not modelled 98.4 22 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
62c2p51A_



not modelled 98.3 24 PDB header:hydrolase, gene regulation
Chain: A: PDB Molecule:spcc18.06c protein;
PDBTitle: crystal structure of the s. pombe pop2p deadenylation2 subunit
63d1j9aa_



not modelled 98.3 13 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
64d3b6oa1



not modelled 98.3 14 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
65c3tr8A_



not modelled 98.2 17 PDB header:hydrolase
Chain: A: PDB Molecule:oligoribonuclease;
PDBTitle: structure of an oligoribonuclease (orn) from coxiella burnetii
66c1d5aA_



not modelled 98.2 24 PDB header:transferase
Chain: A: PDB Molecule:protein (dna polymerase);
PDBTitle: crystal structure of an archaebacterial dna polymerase2 d.tok. deposition of second native structure at 2.43 angstrom
67d1q8ia1



not modelled 98.2 18 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
68c2vwkA_



not modelled 98.2 22 PDB header:dna replication
Chain: A: PDB Molecule:dna polymerase;
PDBTitle: uracil recognition in archaeal dna polymerases captured by2 x-ray crystallography. v93q polymerase variant
69c1s5jA_



not modelled 98.1 19 PDB header:transferase
Chain: A: PDB Molecule:dna polymerase i;
PDBTitle: insight in dna replication: the crystal structure of dna2 polymerase b1 from the archaeon sulfolobus solfataricus
70d2igia1



not modelled 98.0 14 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
71d1ih7a1



not modelled 98.0 24 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
72d1noya_



not modelled 98.0 16 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
73c2gbzA_



not modelled 98.0 12 PDB header:hydrolase
Chain: A: PDB Molecule:oligoribonuclease;
PDBTitle: the crystal structure of xc847 from xanthomonas campestris: a 3-52 oligoribonuclease of dnaq fold family with a novel opposingly-shifted3 helix
74c1q8iA_



not modelled 97.9 19 PDB header:transferase
Chain: A: PDB Molecule:dna polymerase ii;
PDBTitle: crystal structure of escherichia coli dna polymerase ii
75c3iayA_



not modelled 97.7 17 PDB header:transferase/dna
Chain: A: PDB Molecule:dna polymerase delta catalytic subunit;
PDBTitle: ternary complex of dna polymerase delta
76c2xriA_



not modelled 97.7 12 PDB header:hydrolase
Chain: A: PDB Molecule:eri1 exoribonuclease 3;
PDBTitle: crystal structure of human eri1 exoribonuclease 3
77c3cm6A_



not modelled 97.4 11 PDB header:hydrolase, apoptosis
Chain: A: PDB Molecule:cell death-related nuclease 4;
PDBTitle: crystal structure of cell-death related nuclease 4 (crn-4)2 bound with er
78c2gv9B_



not modelled 97.3 21 PDB header:transferase
Chain: B: PDB Molecule:dna polymerase;
PDBTitle: crystal structure of the herpes simplex virus type 1 dna polymerase
79d1w0ha_



not modelled 97.3 6 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
80c2dtuA_



not modelled 97.3 23 PDB header:transferase/dna
Chain: A: PDB Molecule:dna polymerase;
PDBTitle: crystal structure of the beta hairpin loop deletion variant2 of rb69 gp43 in complex with dna containing an abasic site3 analog
81c1zbhA_



not modelled 97.1 10 PDB header:hydrolase/rna
Chain: A: PDB Molecule:3'-5' exonuclease eri1;
PDBTitle: 3'-end specific recognition of histone mrna stem-loop by 3'-2 exonuclease
82c3d45B_



not modelled 97.1 23 PDB header:hydrolase
Chain: B: PDB Molecule:poly(a)-specific ribonuclease parn;
PDBTitle: crystal structure of mouse parn in complex with m7gpppg
83c1kftA_



not modelled 97.1 37 PDB header:dna binding protein
Chain: A: PDB Molecule:excinuclease abc subunit c;
PDBTitle: solution structure of the c-terminal domain of uvrc from e-2 coli
84d1kfta_



not modelled 97.1 37 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:Excinuclease UvrC C-terminal domain
85d1x2ia1



not modelled 97.0 26 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:Hef domain-like
86d2bgwa1



not modelled 96.9 28 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:Hef domain-like
87c2nrzB_



not modelled 96.7 28 PDB header:hydrolase
Chain: B: PDB Molecule:uvrabc system protein c;
PDBTitle: crystal structure of the c-terminal half of uvrc bound to2 its catalytic divalent cation
88d2a1jb1



not modelled 96.7 30 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:Hef domain-like
89d1dgsa1



not modelled 96.2 20 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:NAD+-dependent DNA ligase, domain 3
90c1zbuB_



not modelled 96.2 6 PDB header:hydrolase
Chain: B: PDB Molecule:3'-5' exonuclease eri1;
PDBTitle: crystal structure of full-length 3'-exonuclease
91d1cuka2



not modelled 96.1 23 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:DNA helicase RuvA subunit, middle domain
92d2i1qa1



not modelled 95.8 19 Fold:SAM domain-like
Superfamily:Rad51 N-terminal domain-like
Family:DNA repair protein Rad51, N-terminal domain
93c1d8lA_



not modelled 95.7 24 PDB header:gene regulation
Chain: A: PDB Molecule:protein (holliday junction dna helicase ruva);
PDBTitle: e. coli holliday junction binding protein ruva nh2 region2 lacking domain iii
94c2a1sC_



not modelled 95.2 31 PDB header:hydrolase
Chain: C: PDB Molecule:poly(a)-specific ribonuclease parn;
PDBTitle: crystal structure of native parn nuclease domain
95d2aq0a1



not modelled 95.2 26 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:Hef domain-like
96c1hjpA_



not modelled 95.1 26 PDB header:dna recombination
Chain: A: PDB Molecule:ruva;
PDBTitle: holliday junction binding protein ruva from e. coli
97d1ixra1



not modelled 95.1 35 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:DNA helicase RuvA subunit, middle domain
98d1pzna1



not modelled 95.1 24 Fold:SAM domain-like
Superfamily:Rad51 N-terminal domain-like
Family:DNA repair protein Rad51, N-terminal domain
99c1ixrA_



not modelled 95.0 35 PDB header:hydrolase
Chain: A: PDB Molecule:holliday junction dna helicase ruva;
PDBTitle: ruva-ruvb complex
100c2owoA_



not modelled 94.9 24 PDB header:ligase/dna
Chain: A: PDB Molecule:dna ligase;
PDBTitle: last stop on the road to repair: structure of e.coli dna ligase bound2 to nicked dna-adenylate
101c2h5xA_



not modelled 94.9 27 PDB header:dna binding protein
Chain: A: PDB Molecule:holliday junction atp-dependent dna helicase ruva;
PDBTitle: ruva from mycobacterium tuberculosis
102d1qtma1



not modelled 94.7 34 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
103c2bhnD_



not modelled 94.2 30 PDB header:hydrolase
Chain: D: PDB Molecule:xpf endonuclease;
PDBTitle: xpf from aeropyrum pernix
104c2ex3I_



not modelled 94.1 14 PDB header:transferase/replication
Chain: I: PDB Molecule:dna polymerase;
PDBTitle: bacteriophage phi29 dna polymerase bound to terminal protein
105c1dgsB_



not modelled 94.0 27 PDB header:ligase
Chain: B: PDB Molecule:dna ligase;
PDBTitle: crystal structure of nad+-dependent dna ligase from t.2 filiformis
106d1bvsa2



not modelled 93.9 28 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:DNA helicase RuvA subunit, middle domain
107c1v9pB_



not modelled 93.5 26 PDB header:ligase
Chain: B: PDB Molecule:dna ligase;
PDBTitle: crystal structure of nad+-dependent dna ligase
108c3spaA_



not modelled 93.1 22 PDB header:transferase
Chain: A: PDB Molecule:dna-directed rna polymerase, mitochondrial;
PDBTitle: crystal structure of human mitochondrial rna polymerase
109d1mswd_



not modelled 92.2 22 Fold:DNA/RNA polymerases
Superfamily:DNA/RNA polymerases
Family:T7 RNA polymerase
110c3c1zA_



not modelled 92.0 16 PDB header:dna binding protein
Chain: A: PDB Molecule:dna integrity scanning protein disa;
PDBTitle: structure of the ligand-free form of a bacterial dna damage2 sensor protein
111c2w9mB_



not modelled 91.2 25 PDB header:dna replication
Chain: B: PDB Molecule:polymerase x;
PDBTitle: structure of family x dna polymerase from deinococcus2 radiodurans
112d1szpa1



not modelled 90.9 14 Fold:SAM domain-like
Superfamily:Rad51 N-terminal domain-like
Family:DNA repair protein Rad51, N-terminal domain
113c2qipA_



not modelled 90.6 22 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:protein of unknown function vpa0982;
PDBTitle: crystal structure of a protein of unknown function vpa0982 from vibrio2 parahaemolyticus rimd 2210633
114c1nomA_



not modelled 90.6 26 PDB header:nucleotidyltransferase
Chain: A: PDB Molecule:dna polymerase beta;
PDBTitle: dna polymerase beta (pol b) (e.c.2.7.7.7), 31-kd domain; soaked in the2 presence of mncl2 (5 millimolar)
115c3majA_



not modelled 90.5 13 PDB header:dna binding protein
Chain: A: PDB Molecule:dna processing chain a;
PDBTitle: crystal structure of putative dna processing protein dpra from2 rhodopseudomonas palustris cga009
116c2ihmA_



not modelled 89.8 33 PDB header:transferase/dna
Chain: A: PDB Molecule:dna polymerase mu;
PDBTitle: polymerase mu in ternary complex with gapped 11mer dna2 duplex and bound incoming nucleotide
117d2py5a1



not modelled 88.2 16 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
118c2csdB_



not modelled 87.7 43 PDB header:isomerase
Chain: B: PDB Molecule:topoisomerase v;
PDBTitle: crystal structure of topoisomerase v (61 kda fragment)
119d2fmpa2



not modelled 86.8 16 Fold:SAM domain-like
Superfamily:PsbU/PolX domain-like
Family:DNA polymerase beta-like, second domain
120c8iczA_



not modelled 86.5 21 PDB header:transferase/dna
Chain: A: PDB Molecule:protein (dna polymerase beta (e.c.2.7.7.7));
PDBTitle: dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with2 seven base pairs of dna; soaked in the presence of of datp3 (1 millimolar), mncl2 (5 millimolar), and lithium sulfate4 (75 millimolar)

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0