PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3q8lA_

Fold library id	PDB Header	Molecule	Title
c3q8lA_	PDB header: hydrolase/dna	Chain: A: PDB Molecule: flap endonuclease 1;	PDBTitle: crystal structure of human flap endonuclease fen1 (wt) in complex with2 substrate 5'-flap dna, sm3+, and k+

Links to external resources
Added to library: Sat Apr 30 08:59:28 2011

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence G I Q G L A K L I A D V A P S A I R E N D I K S Y F G R K V A I D A S M S I Y Q F L I A V R Q G G D V L Q N E E G E T T S H L M G M F Y R T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
G G G
G G G G T T
T T
B
T T S
B

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence I R M M E N G I K P V Y V F D G K P P Q L K S G E L A K R S E R R A E A E K Q L Q Q A Q A A G A E Q E V E K F T K R L V K V T K Q H N D E C

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S
G G G T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence K H L L S L M G I P Y L D A P S E A E A S C A A L V K A G K V Y A A A T E D M D C L T F G S P V L M R H L T A S E A K K L P I Q E F H L S R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S S
T T S S S
S
T T T
S S
T T
S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence I L Q E L G L N Q E Q F V D L C I L L G S D Y C E S I R G I G P K R A V D L I Q K H K S I E E I V R R L D P N K Y P V P E N W L H K E A H Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
B T T B
T T
S S
T T T S
T T

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 .

Sequence L F L E P E V L D P E S V E L K W S E P N E E E L I K F M C G E K Q F S E E R I R S G V K R L S K S R Q G S T L E V L F Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T T S
T T T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	G	I	Q	G	L	A	K	L	I	A	D	V	A	P	S	A	I	R	E	N	D	I	K	S	Y	F	G	R	K	V	A	I	D	A	S	M	S	I	Y	Q	F	L	I	A	V	R	Q	G	G	D	V	L	Q	N	E	E	G	E	T	T	S	H	L	M	G	M	F	Y	R	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T										G	G	G						G	G	G	G	T	T																					T	T				B		T	T	S		B
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	I	R	M	M	E	N	G	I	K	P	V	Y	V	F	D	G	K	P	P	Q	L	K	S	G	E	L	A	K	R	S	E	R	R	A	E	A	E	K	Q	L	Q	Q	A	Q	A	A	G	A	E	Q	E	V	E	K	F	T	K	R	L	V	K	V	T	K	Q	H	N	D	E	C
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T	T										S			G	G	G																								T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	K	H	L	L	S	L	M	G	I	P	Y	L	D	A	P	S	E	A	E	A	S	C	A	A	L	V	K	A	G	K	V	Y	A	A	A	T	E	D	M	D	C	L	T	F	G	S	P	V	L	M	R	H	L	T	A	S	E	A	K	K	L	P	I	Q	E	F	H	L	S	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T							S	S												T	T	S	S	S					S		T					T	T		S					S					T	T			S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	I	L	Q	E	L	G	L	N	Q	E	Q	F	V	D	L	C	I	L	L	G	S	D	Y	C	E	S	I	R	G	I	G	P	K	R	A	V	D	L	I	Q	K	H	K	S	I	E	E	I	V	R	R	L	D	P	N	K	Y	P	V	P	E	N	W	L	H	K	E	A	H	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T															B	T	T	B				T	T															S								S		T	T	T	S				T	T
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.
Sequence	L	F	L	E	P	E	V	L	D	P	E	S	V	E	L	K	W	S	E	P	N	E	E	E	L	I	K	F	M	C	G	E	K	Q	F	S	E	E	R	I	R	S	G	V	K	R	L	S	K	S	R	Q	G	S	T	L	E	V	L	F	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S						T	T	T	S																	T	T	T	T