Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP37690
DateThu Jan 5 11:57:02 GMT 2012
Unique Job ID02676dfa28fa15fd

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2gu1A_
Top template information
PDB header:hydrolase
Chain: A: PDB Molecule:zinc peptidase;
PDBTitle: crystal structure of a zinc containing peptidase from2 vibrio cholerae
Confidence and coverage
Confidence:100.0% Coverage: 35%
147 residues ( 35% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
388 residues ( 93%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MTRAVKPRRFAIRPIIYASVLSAGVLLCAFSAHADERDQLKSIQADIAAKERAVRQKQQQ
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Disorder  ????????

















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   .........70.........80.........90.........100.........110.........120
Sequence  RASLLAQLKKQEEAISEATRKLRETQNTLNQLNKQIDEMNASIAKLEQQKAAQERSLAAQ
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   .........130.........140.........150.........160.........170.........180
Sequence  LDAAFRQGEHTGIQLILSGEESQRGQRLQAYFGYLNQARQETIAQLKQTREEVAMQRAEL
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   .........190.........200.........210.........220.........230.........240
Sequence  EEKQSEQQTLLYEQRAQQAKLTQALNERKKTLAGLESSIQQGQQQLSELRANESRLRNSI
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   .........250.........260.........270.........280.........290.........300
Sequence  ARAEAAAKARAEREAREAQAVRDRQKEATRKGTTYKPTESEKSLMSRTGGLGAPRGQAFW
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???????????????????????????????????????


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   .........310.........320.........330.........340.........350.........360
Sequence  PVRGPTLHRYGEQLQGELRWKGMVIGASEGTEVKAIADGRVILADWLQGYGLVVVVEHGK
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   .........370.........380.........390.........400.........410.........
Sequence  GDMSLYGYNQSALVSVGSQVRAGQPIALVGSSGGQGRPSLYFEIRRQGQAVNPQPWLGR
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?

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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2gu1 chain A

3D model

Region: 271 - 417
Aligned: 147
Modelled: 147
Confidence: 100.0%
Identity: 23%
PDB header:hydrolase
Chain: A: PDB Molecule:zinc peptidase;
PDBTitle: crystal structure of a zinc containing peptidase from2 vibrio cholerae

Phyre2

PDB 2hsi chain B

3D model

Region: 289 - 418
Aligned: 123
Modelled: 130
Confidence: 100.0%
Identity: 28%
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative peptidase m23;
PDBTitle: crystal structure of putative peptidase m23 from2 pseudomonas aeruginosa, new york structural genomics3 consortium

Phyre2

PDB 1qwy chain A

3D model

Region: 280 - 418
Aligned: 137
Modelled: 139
Confidence: 100.0%
Identity: 27%
Fold: Barrel-sandwich hybrid
Superfamily: Duplicated hybrid motif
Family: Peptidoglycan hydrolase LytM

Phyre2

PDB 3nyy chain A

3D model

Region: 291 - 418
Aligned: 128
Modelled: 128
Confidence: 100.0%
Identity: 25%
PDB header:hydrolase
Chain: A: PDB Molecule:putative glycyl-glycine endopeptidase lytm;
PDBTitle: crystal structure of a putative glycyl-glycine endopeptidase lytm2 (rumgna_02482) from ruminococcus gnavus atcc 29149 at 1.60 a3 resolution

Phyre2

PDB 2b44 chain A

3D model

Region: 298 - 418
Aligned: 120
Modelled: 121
Confidence: 99.9%
Identity: 31%
PDB header:hydrolase
Chain: A: PDB Molecule:glycyl-glycine endopeptidase lytm;
PDBTitle: truncated s. aureus lytm, p 32 2 1 crystal form

Phyre2

PDB 3it5 chain B

3D model

Region: 292 - 412
Aligned: 121
Modelled: 121
Confidence: 99.9%
Identity: 21%
PDB header:hydrolase
Chain: B: PDB Molecule:protease lasa;
PDBTitle: crystal structure of the lasa virulence factor from pseudomonas2 aeruginosa

Phyre2

PDB 3csq chain C

3D model

Region: 300 - 414
Aligned: 110
Modelled: 115
Confidence: 99.8%
Identity: 14%
PDB header:hydrolase
Chain: C: PDB Molecule:morphogenesis protein 1;
PDBTitle: crystal and cryoem structural studies of a cell wall2 degrading enzyme in the bacteriophage phi29 tail

Phyre2

PDB 1c1g chain A

3D model

Region: 34 - 267
Aligned: 234
Modelled: 234
Confidence: 98.1%
Identity: 14%
PDB header:contractile protein
Chain: A: PDB Molecule:tropomyosin;
PDBTitle: crystal structure of tropomyosin at 7 angstroms resolution2 in the spermine-induced crystal form

Phyre2

PDB 1cii chain A

3D model

Region: 31 - 267
Aligned: 234
Modelled: 234
Confidence: 97.6%
Identity: 11%
PDB header:transmembrane protein
Chain: A: PDB Molecule:colicin ia;
PDBTitle: colicin ia

Phyre2

PDB 3na7 chain A

3D model

Region: 36 - 311
Aligned: 224
Modelled: 225
Confidence: 97.6%
Identity: 12%
PDB header:gene regulation, chaperone
Chain: A: PDB Molecule:hp0958;
PDBTitle: 2.2 angstrom structure of the hp0958 protein from helicobacter pylori2 ccug 17874

Phyre2

PDB 1yvl chain B

3D model

Region: 32 - 265
Aligned: 234
Modelled: 234
Confidence: 97.5%
Identity: 11%
PDB header:signaling protein
Chain: B: PDB Molecule:signal transducer and activator of transcription
PDBTitle: structure of unphosphorylated stat1

Phyre2

PDB 1bg1 chain A

3D model

Region: 45 - 214
Aligned: 170
Modelled: 170
Confidence: 97.5%
Identity: 13%
PDB header:transcription/dna
Chain: A: PDB Molecule:protein (transcription factor stat3b);
PDBTitle: transcription factor stat3b/dna complex

Phyre2

PDB 2oev chain A

3D model

Region: 36 - 257
Aligned: 221
Modelled: 222
Confidence: 97.5%
Identity: 8%
PDB header:protein transport
Chain: A: PDB Molecule:programmed cell death 6-interacting protein;
PDBTitle: crystal structure of alix/aip1

Phyre2

PDB 1bf5 chain A

3D model

Region: 38 - 194
Aligned: 157
Modelled: 157
Confidence: 97.4%
Identity: 8%
PDB header:gene regulation/dna
Chain: A: PDB Molecule:signal transducer and activator of transcription
PDBTitle: tyrosine phosphorylated stat-1/dna complex

Phyre2

PDB 3oja chain B

3D model

Region: 40 - 185
Aligned: 146
Modelled: 146
Confidence: 97.3%
Identity: 11%
PDB header:protein binding
Chain: B: PDB Molecule:anopheles plasmodium-responsive leucine-rich repeat protein
PDBTitle: crystal structure of lrim1/apl1c complex

Phyre2

PDB 1deq chain F

3D model

Region: 153 - 353
Aligned: 188
Modelled: 201
Confidence: 97.2%
Identity: 11%
PDB header:
PDB COMPND:

Phyre2

PDB 3cwg chain A

3D model

Region: 38 - 198
Aligned: 159
Modelled: 161
Confidence: 97.2%
Identity: 9%
PDB header:transcription
Chain: A: PDB Molecule:signal transducer and activator of transcription
PDBTitle: unphosphorylated mouse stat3 core fragment

Phyre2

PDB 2efr chain B

3D model

Region: 40 - 190
Aligned: 151
Modelled: 151
Confidence: 97.0%
Identity: 13%
PDB header:contractile protein
Chain: B: PDB Molecule:general control protein gcn4 and tropomyosin 1 alpha chain;
PDBTitle: crystal structure of the c-terminal tropomyosin fragment with n- and2 c-terminal extensions of the leucine zipper at 1.8 angstroms3 resolution

Phyre2

PDB 3ghg chain K

3D model

Region: 164 - 405
Aligned: 232
Modelled: 242
Confidence: 97.0%
Identity: 12%
PDB header:blood clotting
Chain: K: PDB Molecule:fibrinogen beta chain;
PDBTitle: crystal structure of human fibrinogen

Phyre2

PDB 1jch chain C

3D model

Region: 35 - 247
Aligned: 210
Modelled: 213
Confidence: 96.9%
Identity: 7%
PDB header:ribosome inhibitor, hydrolase
Chain: C: PDB Molecule:colicin e3;
PDBTitle: crystal structure of colicin e3 in complex with its immunity protein

Phyre2

PDB 1i84 chain V

3D model

Region: 2 - 122
Aligned: 121
Modelled: 121
Confidence: 74.0%
Identity: 9%
PDB header:contractile protein
Chain: V: PDB Molecule:smooth muscle myosin heavy chain;
PDBTitle: cryo-em structure of the heavy meromyosin subfragment of2 chicken gizzard smooth muscle myosin with regulatory light3 chain in the dephosphorylated state. only c alphas4 provided for regulatory light chain. only backbone atoms5 provided for s2 fragment.

Phyre2
1

c2gu1A_
2

c2hsiB_
3

d1qwya_
4

c3nyyA_
5

c2b44A_
6

c3it5B_
7

c3csqC_
8

c1c1gA_
9

c1ciiA_
10

c3na7A_
11

c1yvlB_
12

c1bg1A_
13

c2oevA_
14

c1bf5A_
15

c3ojaB_
16

c1deqF_
17

c3cwgA_
18

c2efrB_
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c3ghgK_
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c1jchC_
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c1i84V_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2gu1A_



100.0 23 PDB header:hydrolase
Chain: A: PDB Molecule:zinc peptidase;
PDBTitle: crystal structure of a zinc containing peptidase from2 vibrio cholerae
2c2hsiB_



100.0 28 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative peptidase m23;
PDBTitle: crystal structure of putative peptidase m23 from2 pseudomonas aeruginosa, new york structural genomics3 consortium
3d1qwya_



100.0 27 Fold:Barrel-sandwich hybrid
Superfamily:Duplicated hybrid motif
Family:Peptidoglycan hydrolase LytM
4c3nyyA_



100.0 25 PDB header:hydrolase
Chain: A: PDB Molecule:putative glycyl-glycine endopeptidase lytm;
PDBTitle: crystal structure of a putative glycyl-glycine endopeptidase lytm2 (rumgna_02482) from ruminococcus gnavus atcc 29149 at 1.60 a3 resolution
5c2b44A_



99.9 31 PDB header:hydrolase
Chain: A: PDB Molecule:glycyl-glycine endopeptidase lytm;
PDBTitle: truncated s. aureus lytm, p 32 2 1 crystal form
6c3it5B_



99.9 21 PDB header:hydrolase
Chain: B: PDB Molecule:protease lasa;
PDBTitle: crystal structure of the lasa virulence factor from pseudomonas2 aeruginosa
7c3csqC_



99.8 14 PDB header:hydrolase
Chain: C: PDB Molecule:morphogenesis protein 1;
PDBTitle: crystal and cryoem structural studies of a cell wall2 degrading enzyme in the bacteriophage phi29 tail
8c1c1gA_



98.1 14 PDB header:contractile protein
Chain: A: PDB Molecule:tropomyosin;
PDBTitle: crystal structure of tropomyosin at 7 angstroms resolution2 in the spermine-induced crystal form
9c1ciiA_



97.6 11 PDB header:transmembrane protein
Chain: A: PDB Molecule:colicin ia;
PDBTitle: colicin ia
10c3na7A_



97.6 12 PDB header:gene regulation, chaperone
Chain: A: PDB Molecule:hp0958;
PDBTitle: 2.2 angstrom structure of the hp0958 protein from helicobacter pylori2 ccug 17874
11c1yvlB_



97.5 11 PDB header:signaling protein
Chain: B: PDB Molecule:signal transducer and activator of transcription
PDBTitle: structure of unphosphorylated stat1
12c1bg1A_



97.5 13 PDB header:transcription/dna
Chain: A: PDB Molecule:protein (transcription factor stat3b);
PDBTitle: transcription factor stat3b/dna complex
13c2oevA_



97.5 8 PDB header:protein transport
Chain: A: PDB Molecule:programmed cell death 6-interacting protein;
PDBTitle: crystal structure of alix/aip1
14c1bf5A_



97.4 8 PDB header:gene regulation/dna
Chain: A: PDB Molecule:signal transducer and activator of transcription
PDBTitle: tyrosine phosphorylated stat-1/dna complex
15c3ojaB_



97.3 11 PDB header:protein binding
Chain: B: PDB Molecule:anopheles plasmodium-responsive leucine-rich repeat protein
PDBTitle: crystal structure of lrim1/apl1c complex
16c1deqF_



97.2 11 PDB header:
PDB COMPND:
17c3cwgA_



97.2 9 PDB header:transcription
Chain: A: PDB Molecule:signal transducer and activator of transcription
PDBTitle: unphosphorylated mouse stat3 core fragment
18c2efrB_



97.0 13 PDB header:contractile protein
Chain: B: PDB Molecule:general control protein gcn4 and tropomyosin 1 alpha chain;
PDBTitle: crystal structure of the c-terminal tropomyosin fragment with n- and2 c-terminal extensions of the leucine zipper at 1.8 angstroms3 resolution
19c3ghgK_



97.0 12 PDB header:blood clotting
Chain: K: PDB Molecule:fibrinogen beta chain;
PDBTitle: crystal structure of human fibrinogen
20c1jchC_



96.9 7 PDB header:ribosome inhibitor, hydrolase
Chain: C: PDB Molecule:colicin e3;
PDBTitle: crystal structure of colicin e3 in complex with its immunity protein
21c1deqO_



not modelled 96.9 11 PDB header:
PDB COMPND:
22c2oexB_



not modelled 96.8 8 PDB header:protein transport
Chain: B: PDB Molecule:programmed cell death 6-interacting protein;
PDBTitle: structure of alix/aip1 v domain
23c2d3eD_



not modelled 96.5 11 PDB header:contractile protein
Chain: D: PDB Molecule:general control protein gcn4 and tropomyosin 1
PDBTitle: crystal structure of the c-terminal fragment of rabbit2 skeletal alpha-tropomyosin
24c1ei3E_



not modelled 96.5 10 PDB header:
PDB COMPND:
25d2f3ga_



not modelled 96.4 17 Fold:Barrel-sandwich hybrid
Superfamily:Duplicated hybrid motif
Family:Glucose permease-like
26d1glaf_



not modelled 96.4 17 Fold:Barrel-sandwich hybrid
Superfamily:Duplicated hybrid motif
Family:Glucose permease-like
27c2v71A_



not modelled 96.2 10 PDB header:nuclear protein
Chain: A: PDB Molecule:nuclear distribution protein nude-like 1;
PDBTitle: coiled-coil region of nudel
28d2gpra_



not modelled 96.0 16 Fold:Barrel-sandwich hybrid
Superfamily:Duplicated hybrid motif
Family:Glucose permease-like
29c2fxmB_



not modelled 96.0 12 PDB header:contractile protein
Chain: B: PDB Molecule:myosin heavy chain, cardiac muscle beta isoform;
PDBTitle: structure of the human beta-myosin s2 fragment
30c3u59C_



not modelled 95.9 9 PDB header:contractile protein
Chain: C: PDB Molecule:tropomyosin beta chain;
PDBTitle: n-terminal 98-aa fragment of smooth muscle tropomyosin beta
31d1gpra_



not modelled 95.9 17 Fold:Barrel-sandwich hybrid
Superfamily:Duplicated hybrid motif
Family:Glucose permease-like
32c3ol1A_



not modelled 95.9 13 PDB header:structural protein
Chain: A: PDB Molecule:vimentin;
PDBTitle: crystal structure of vimentin (fragment 144-251) from homo sapiens,2 northeast structural genomics consortium target hr4796b
33c3o0zD_



not modelled 95.8 9 PDB header:transferase
Chain: D: PDB Molecule:rho-associated protein kinase 1;
PDBTitle: crystal structure of a coiled-coil domain from human rock i
34c2aukA_



not modelled 95.6 14 PDB header:transferase
Chain: A: PDB Molecule:dna-directed rna polymerase beta' chain;
PDBTitle: structure of e. coli rna polymerase beta' g/g' insert
35c1ei3C_



not modelled 95.6 12 PDB header:
PDB COMPND:
36c3l9oA_



not modelled 95.5 7 PDB header:hydrolase
Chain: A: PDB Molecule:atp-dependent rna helicase dob1;
PDBTitle: crystal structure of mtr4, a co-factor of the nuclear exosome
37c3r6nA_



not modelled 95.5 9 PDB header:cell adhesion
Chain: A: PDB Molecule:desmoplakin;
PDBTitle: crystal structure of a rigid four spectrin repeat fragment of the2 human desmoplakin plakin domain
38c2gl2B_



not modelled 95.3 10 PDB header:cell adhesion
Chain: B: PDB Molecule:adhesion a;
PDBTitle: crystal structure of the tetra muntant (t66g,r67g,f68g,2 y69g) of bacterial adhesin fada
39c3hnwB_



not modelled 95.2 11 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a basic coiled-coil protein of unknown function2 from eubacterium eligens atcc 27750
40c2i1jA_



not modelled 95.1 8 PDB header:cell adhesion, membrane protein
Chain: A: PDB Molecule:moesin;
PDBTitle: moesin from spodoptera frugiperda at 2.1 angstroms resolution
41c3ojaA_



not modelled 94.8 13 PDB header:protein binding
Chain: A: PDB Molecule:leucine-rich immune molecule 1;
PDBTitle: crystal structure of lrim1/apl1c complex
42c2y3aB_



not modelled 94.6 10 PDB header:transferase
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta;
PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
43c1q90A_



not modelled 94.2 21 PDB header:photosynthesis
Chain: A: PDB Molecule:apocytochrome f;
PDBTitle: structure of the cytochrome b6f (plastohydroquinone : plastocyanin2 oxidoreductase) from chlamydomonas reinhardtii
44c1e2vB_



not modelled 94.2 21 PDB header:electron transport proteins
Chain: B: PDB Molecule:cytochrome f;
PDBTitle: n153q mutant of cytochrome f from chlamydomonas reinhardtii
45c3dtpA_



not modelled 94.0 10 PDB header:contractile protein
Chain: A: PDB Molecule:myosin 2 heavy chain chimera of smooth and
PDBTitle: tarantula heavy meromyosin obtained by flexible docking to2 tarantula muscle thick filament cryo-em 3d-map
46c2kccA_



not modelled 93.9 18 PDB header:ligase
Chain: A: PDB Molecule:acetyl-coa carboxylase 2;
PDBTitle: solution structure of biotinoyl domain from human acetyl-2 coa carboxylase 2
47c1f5nA_



not modelled 93.9 10 PDB header:signaling protein
Chain: A: PDB Molecule:interferon-induced guanylate-binding protein 1;
PDBTitle: human guanylate binding protein-1 in complex with the gtp2 analogue, gmppnp.
48c1g8xB_



not modelled 93.7 7 PDB header:structural protein
Chain: B: PDB Molecule:myosin ii heavy chain fused to alpha-actinin 3;
PDBTitle: structure of a genetically engineered molecular motor
49c3g67A_



not modelled 93.4 12 PDB header:signaling protein
Chain: A: PDB Molecule:methyl-accepting chemotaxis protein;
PDBTitle: crystal structure of a soluble chemoreceptor from thermotoga2 maritima
50c1ctmA_



not modelled 93.3 17 PDB header:electron transport(cytochrome)
Chain: A: PDB Molecule:cytochrome f;
PDBTitle: crystal structure of chloroplast cytochrome f reveals a2 novel cytochrome fold and unexpected heme ligation
51d1dcza_



not modelled 93.2 25 Fold:Barrel-sandwich hybrid
Superfamily:Single hybrid motif
Family:Biotinyl/lipoyl-carrier proteins and domains
52c1sjjB_



not modelled 92.7 8 PDB header:contractile protein
Chain: B: PDB Molecule:actinin;
PDBTitle: cryo-em structure of chicken gizzard smooth muscle alpha-2 actinin
53c2b9cA_



not modelled 92.7 11 PDB header:contractile protein
Chain: A: PDB Molecule:striated-muscle alpha tropomyosin;
PDBTitle: structure of tropomyosin's mid-region: bending and binding2 sites for actin
54d1ci3m2



not modelled 91.9 22 Fold:Barrel-sandwich hybrid
Superfamily:Rudiment single hybrid motif
Family:Cytochrome f, small domain
55c2jxmB_



not modelled 91.8 23 PDB header:electron transport
Chain: B: PDB Molecule:cytochrome f;
PDBTitle: ensemble of twenty structures of the prochlorothrix2 hollandica plastocyanin- cytochrome f complex
56c2ch7A_



not modelled 91.6 9 PDB header:chemotaxis
Chain: A: PDB Molecule:methyl-accepting chemotaxis protein;
PDBTitle: crystal structure of the cytoplasmic domain of a bacterial2 chemoreceptor from thermotoga maritima
57c2b8gA_



not modelled 91.6 18 PDB header:biosynthetic protein
Chain: A: PDB Molecule:biotin/lipoyl attachment protein;
PDBTitle: solution structure of bacillus subtilis blap biotinylated-2 form (energy minimized mean structure)
58d1e2wa2



not modelled 91.4 29 Fold:Barrel-sandwich hybrid
Superfamily:Rudiment single hybrid motif
Family:Cytochrome f, small domain
59d1brwa3



not modelled 91.4 27 Fold:alpha/beta-Hammerhead
Superfamily:Pyrimidine nucleoside phosphorylase C-terminal domain
Family:Pyrimidine nucleoside phosphorylase C-terminal domain
60d1bdoa_



not modelled 91.0 23 Fold:Barrel-sandwich hybrid
Superfamily:Single hybrid motif
Family:Biotinyl/lipoyl-carrier proteins and domains
61c4a55B_



not modelled 90.9 10 PDB header:transferase
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit alpha;
PDBTitle: crystal structure of p110alpha in complex with ish2 of p85alpha and2 the inhibitor pik-108
62c3tnfB_



not modelled 90.8 9 PDB header:protein transport
Chain: B: PDB Molecule:lida;
PDBTitle: lida from legionella in complex with active rab8a
63c2ejgD_



not modelled 90.7 28 PDB header:ligase
Chain: D: PDB Molecule:149aa long hypothetical methylmalonyl-coa decarboxylase
PDBTitle: crystal structure of the biotin protein ligase (mutation r48a) and2 biotin carboxyl carrier protein complex from pyrococcus horikoshii3 ot3
64c3ipkA_



not modelled 90.1 15 PDB header:cell adhesion
Chain: A: PDB Molecule:agi/ii;
PDBTitle: crystal structure of a3vp1 of agi/ii of streptococcus mutans
65c2wpqA_



not modelled 89.7 16 PDB header:membrane protein
Chain: A: PDB Molecule:trimeric autotransporter adhesin fragment;
PDBTitle: salmonella enterica sada 479-519 fused to gcn4 adaptors (2 sadak3, in-register fusion)
66d2tpta3



not modelled 89.7 24 Fold:alpha/beta-Hammerhead
Superfamily:Pyrimidine nucleoside phosphorylase C-terminal domain
Family:Pyrimidine nucleoside phosphorylase C-terminal domain
67c1l8dB_



not modelled 89.3 16 PDB header:replication
Chain: B: PDB Molecule:dna double-strand break repair rad50 atpase;
PDBTitle: rad50 coiled-coil zn hook
68c2dn8A_



not modelled 89.1 20 PDB header:ligase
Chain: A: PDB Molecule:acetyl-coa carboxylase 2;
PDBTitle: solution structure of rsgi ruh-053, an apo-biotin carboxy2 carrier protein from human transcarboxylase
69c2xgjA_



not modelled 89.0 8 PDB header:hydrolase/rna
Chain: A: PDB Molecule:atp-dependent rna helicase dob1;
PDBTitle: structure of mtr4, a dexh helicase involved in nuclear rna2 processing and surveillance
70d1ghja_



not modelled 88.5 23 Fold:Barrel-sandwich hybrid
Superfamily:Single hybrid motif
Family:Biotinyl/lipoyl-carrier proteins and domains
71c2j0fC_



not modelled 88.4 37 PDB header:transferase
Chain: C: PDB Molecule:thymidine phosphorylase;
PDBTitle: structural basis for non-competitive product inhibition in2 human thymidine phosphorylase: implication for drug design
72c1y4cA_



not modelled 88.2 14 PDB header:de novo protein
Chain: A: PDB Molecule:maltose binding protein fused with designed
PDBTitle: designed helical protein fusion mbp
73c3u1aC_



not modelled 88.0 16 PDB header:contractile protein
Chain: C: PDB Molecule:smooth muscle tropomyosin alpha;
PDBTitle: n-terminal 81-aa fragment of smooth muscle tropomyosin alpha
74c1otpA_



not modelled 88.0 25 PDB header:phosphorylase
Chain: A: PDB Molecule:thymidine phosphorylase;
PDBTitle: structural and theoretical studies suggest domain movement produces an2 active conformation of thymidine phosphorylase
75c3a7pB_



not modelled 88.0 12 PDB header:protein transport
Chain: B: PDB Molecule:autophagy protein 16;
PDBTitle: the crystal structure of saccharomyces cerevisiae atg16
76c1tu2B_



not modelled 87.9 20 PDB header:electron transport
Chain: B: PDB Molecule:apocytochrome f;
PDBTitle: the complex of nostoc cytochrome f and plastocyanin determin with2 paramagnetic nmr. based on the structures of cytochrome f and3 plastocyanin, 10 structures
77c3hizB_



not modelled 87.7 11 PDB header:transferase/oncoprotein
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit
PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha
78c3h5qA_



not modelled 87.5 23 PDB header:transferase
Chain: A: PDB Molecule:pyrimidine-nucleoside phosphorylase;
PDBTitle: crystal structure of a putative pyrimidine-nucleoside phosphorylase2 from staphylococcus aureus
79c2v66C_



not modelled 86.5 17 PDB header:structural protein
Chain: C: PDB Molecule:nuclear distribution protein nude-like 1;
PDBTitle: crystal structure of the coiled-coil domain of ndel1 (a.a.2 58 to 169)c
80c3n6rK_



not modelled 86.0 14 PDB header:ligase
Chain: K: PDB Molecule:propionyl-coa carboxylase, alpha subunit;
PDBTitle: crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc)
81d1o78a_



not modelled 85.9 24 Fold:Barrel-sandwich hybrid
Superfamily:Single hybrid motif
Family:Biotinyl/lipoyl-carrier proteins and domains
82c2v1yB_



not modelled 85.1 9 PDB header:transferase
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit alpha;
PDBTitle: structure of a phosphoinositide 3-kinase alpha adaptor-2 binding domain (abd) in a complex with the ish2 domain3 from p85 alpha
83c2nrjA_



not modelled 84.7 13 PDB header:toxin
Chain: A: PDB Molecule:hbl b protein;
PDBTitle: crystal structure of hemolysin binding component from2 bacillus cereus
84c1t5eB_



not modelled 84.5 35 PDB header:transport protein
Chain: B: PDB Molecule:multidrug resistance protein mexa;
PDBTitle: the structure of mexa
85c2e75C_



not modelled 84.5 18 PDB header:photosynthesis
Chain: C: PDB Molecule:apocytochrome f;
PDBTitle: crystal structure of the cytochrome b6f complex with 2-nonyl-4-2 hydroxyquinoline n-oxide (nqno) from m.laminosus
86c2zv4O_



not modelled 84.4 10 PDB header:structural protein
Chain: O: PDB Molecule:major vault protein;
PDBTitle: the structure of rat liver vault at 3.5 angstrom resolution
87d1iyua_



not modelled 84.0 24 Fold:Barrel-sandwich hybrid
Superfamily:Single hybrid motif
Family:Biotinyl/lipoyl-carrier proteins and domains
88c3lnnB_



not modelled 83.8 28 PDB header:metal transport
Chain: B: PDB Molecule:membrane fusion protein (mfp) heavy metal cation efflux
PDBTitle: crystal structure of zneb from cupriavidus metallidurans
89c2dq3A_



not modelled 83.7 10 PDB header:ligase
Chain: A: PDB Molecule:seryl-trna synthetase;
PDBTitle: crystal structure of aq_298
90c1deqD_



not modelled 83.7 1 PDB header:
PDB COMPND:
91d1vf7a_



not modelled 83.2 32 Fold:HlyD-like secretion proteins
Superfamily:HlyD-like secretion proteins
Family:HlyD-like secretion proteins
92d1laba_



not modelled 83.1 19 Fold:Barrel-sandwich hybrid
Superfamily:Single hybrid motif
Family:Biotinyl/lipoyl-carrier proteins and domains
93c2f1mA_



not modelled 82.8 19 PDB header:transport protein
Chain: A: PDB Molecule:acriflavine resistance protein a;
PDBTitle: conformational flexibility in the multidrug efflux system protein acra
94d1qjoa_



not modelled 82.6 25 Fold:Barrel-sandwich hybrid
Superfamily:Single hybrid motif
Family:Biotinyl/lipoyl-carrier proteins and domains
95c1brwB_



not modelled 82.5 31 PDB header:transferase
Chain: B: PDB Molecule:protein (pyrimidine nucleoside phosphorylase);
PDBTitle: the crystal structure of pyrimidine nucleoside2 phosphorylase in a closed conformation
96c2qf7A_



not modelled 82.4 19 PDB header:ligase
Chain: A: PDB Molecule:pyruvate carboxylase protein;
PDBTitle: crystal structure of a complete multifunctional pyruvate carboxylase2 from rhizobium etli
97c1qu7A_



not modelled 82.1 12 PDB header:signaling protein
Chain: A: PDB Molecule:methyl-accepting chemotaxis protein i;
PDBTitle: four helical-bundle structure of the cytoplasmic domain of a serine2 chemotaxis receptor
98c2dsjA_



not modelled 81.6 37 PDB header:transferase
Chain: A: PDB Molecule:pyrimidine-nucleoside (thymidine) phosphorylase;
PDBTitle: crystal structure of project id tt0128 from thermus thermophilus hb8
99c2no2A_



not modelled 81.6 15 PDB header:cell adhesion
Chain: A: PDB Molecule:huntingtin-interacting protein 1;
PDBTitle: crystal structure of the dllrkn-containing coiled-coil2 domain of huntingtin-interacting protein 1
100d1k8ma_



not modelled 81.3 9 Fold:Barrel-sandwich hybrid
Superfamily:Single hybrid motif
Family:Biotinyl/lipoyl-carrier proteins and domains
101c3qh9A_



not modelled 81.3 9 PDB header:structural protein
Chain: A: PDB Molecule:liprin-beta-2;
PDBTitle: human liprin-beta2 coiled-coil
102c2k33A_



not modelled 81.2 26 PDB header:membrane protein, transport protein
Chain: A: PDB Molecule:acra;
PDBTitle: solution structure of an n-glycosylated protein using in2 vitro glycosylation
103d1gjxa_



not modelled 81.2 17 Fold:Barrel-sandwich hybrid
Superfamily:Single hybrid motif
Family:Biotinyl/lipoyl-carrier proteins and domains
104c2ejmA_



not modelled 81.0 13 PDB header:ligase
Chain: A: PDB Molecule:methylcrotonoyl-coa carboxylase subunit alpha;
PDBTitle: solution structure of ruh-072, an apo-biotnyl domain form2 human acetyl coenzyme a carboxylase
105c3fppB_



not modelled 80.8 22 PDB header:membrane protein
Chain: B: PDB Molecule:macrolide-specific efflux protein maca;
PDBTitle: crystal structure of e.coli maca
106c2aujD_



not modelled 80.8 23 PDB header:transferase
Chain: D: PDB Molecule:dna-directed rna polymerase beta' chain;
PDBTitle: structure of thermus aquaticus rna polymerase beta'-subunit2 insert
107c1gk4A_



not modelled 80.7 9 PDB header:vimentin
Chain: A: PDB Molecule:vimentin;
PDBTitle: human vimentin coil 2b fragment (cys2)
108c1n73C_



not modelled 80.6 10 PDB header:blood clotting
Chain: C: PDB Molecule:fibrin gamma chain;
PDBTitle: fibrin d-dimer, lamprey complexed with the peptide ligand: gly-his-2 arg-pro-amide
109c1quuA_



not modelled 79.0 9 PDB header:contractile protein
Chain: A: PDB Molecule:human skeletal muscle alpha-actinin 2;
PDBTitle: crystal structure of two central spectrin-like repeats from2 alpha-actinin
110c1hciB_



not modelled 78.9 9 PDB header:triple-helix coiled coil
Chain: B: PDB Molecule:alpha-actinin 2;
PDBTitle: crystal structure of the rod domain of alpha-actinin
111c3fmcC_



not modelled 78.6 20 PDB header:hydrolase
Chain: C: PDB Molecule:putative succinylglutamate desuccinylase / aspartoacylase;
PDBTitle: crystal structure of a putative succinylglutamate desuccinylase /2 aspartoacylase family protein (sama_0604) from shewanella amazonensis3 sb2b at 1.80 a resolution
112c2q8iB_



not modelled 78.6 16 PDB header:transferase
Chain: B: PDB Molecule:dihydrolipoyllysine-residue acetyltransferase component of
PDBTitle: pyruvate dehydrogenase kinase isoform 3 in complex with antitumor drug2 radicicol
113c2qj8B_



not modelled 78.1 12 PDB header:hydrolase
Chain: B: PDB Molecule:mlr6093 protein;
PDBTitle: crystal structure of an aspartoacylase family protein (mlr6093) from2 mesorhizobium loti maff303099 at 2.00 a resolution
114d1y8ob1



not modelled 77.6 16 Fold:Barrel-sandwich hybrid
Superfamily:Single hybrid motif
Family:Biotinyl/lipoyl-carrier proteins and domains
115c2q6oB_



not modelled 77.2 25 PDB header:biosynthetic protein
Chain: B: PDB Molecule:hypothetical protein;
PDBTitle: sall-y70t with sam and cl
116c2l5tA_



not modelled 75.7 23 PDB header:transferase
Chain: A: PDB Molecule:lipoamide acyltransferase;
PDBTitle: solution nmr structure of e2 lipoyl domain from thermoplasma2 acidophilum
117c2dneA_



not modelled 74.8 18 PDB header:transferase
Chain: A: PDB Molecule:dihydrolipoyllysine-residue acetyltransferase
PDBTitle: solution structure of rsgi ruh-058, a lipoyl domain of2 human 2-oxoacid dehydrogenase
118c2jeeA_



not modelled 74.4 14 PDB header:cell cycle
Chain: A: PDB Molecule:yiiu;
PDBTitle: xray structure of e. coli yiiu
119c1i84V_



74.0 9 PDB header:contractile protein
Chain: V: PDB Molecule:smooth muscle myosin heavy chain;
PDBTitle: cryo-em structure of the heavy meromyosin subfragment of2 chicken gizzard smooth muscle myosin with regulatory light3 chain in the dephosphorylated state. only c alphas4 provided for regulatory light chain. only backbone atoms5 provided for s2 fragment.
120d2pnrc1



not modelled 73.3 18 Fold:Barrel-sandwich hybrid
Superfamily:Single hybrid motif
Family:Biotinyl/lipoyl-carrier proteins and domains

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0