PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c1g8xB_

Fold library id	PDB Header	Molecule	Title
c1g8xB_	PDB header: structural protein	Chain: B: PDB Molecule: myosin ii heavy chain fused to alpha-actinin 3;	PDBTitle: structure of a genetically engineered molecular motor

Links to external resources
Added to library: Tue Mar 16 13:53:11 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence N P I H D R T S D Y H K Y L K V K Q G D S D L F K L T V S D K R Y I W Y N P D P D E R D S Y E C G E I V S E T S D S F T F K T V D G Q D R Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G
T T S S S
S
S S
S
S S T T
T T
S S
S S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence V K K D D A N Q R N P I K F D G V E D M S E L S Y L N E P A V F H N L R V R Y N Q D L I Y T Y S G L F L V A V N P F K R I P I Y T Q E M V D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T
B
G G G T T
S B G G G
S S
T T T
T T
S S
S
S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence I F K G R R R N E V A P H I F A I S D V A Y R S M L D D R Q N Q S L L I T G E S G A G K T E N T K K V I Q Y L A S V A G R N Q A N G S G V L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T
T T T S
T
S T T S S S
T T
T T G G G

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence E Q Q I L Q A N P I L E A F G N A K T T R N N N S S E F G K F I E I Q F N N A G F I S G A S I Q S Y L L E K S R V V F Q S E T E R N Y H I F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
T T S S
T T S
G G G G T
T T
B

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence Y Q L L A G A T A E E K K A L H L A G P E S F N Y L N Q S G C V D I K G V S D E D E F K I T R Q A M D I V G F S Q E E Q M S I F K I I A G I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T T
G G G S T T T S S S S
T T
T

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence L H L G N I K F E K G A G E G A V L K D K T A L N A A S T V F G V N P S V L E K A L M E P R I L A G R D L V A Q H L N V E K S S S S R D A L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S S
S
T S
S
B
T T S
B

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480 . . . . . . . . . 490

Sequence V K A L Y G R L F L W L V K K I N N V L C S E R K A Y F I G V L D I S G F E I F K V N S F E Q L C I N Y T N E K L Q Q F F N H H M F K V E Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S
S S B

. . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540 . . . . . . . . . 550 . . . . . . . . . 560

Sequence E E Y L K E K I N W T F I D F G L D S Q A T I D L I D G R Q P P G I L A L L D E Q S V F P N A T D N T L I T K L H S H F S K K N A K Y E E P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G G
S S
T T T T
T T S T T
T T S S T T

. . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600 . . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630

Sequence R F S K T E F G V T H Y A G Q V M Y E I Q D W L E K N K D P L Q Q D L E L C F K D S S D N V V T K L F N D P N I A S R A K K G A N F I T V A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
S S T T
T T T T
T
S S
S
B
S S S B

. . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660 . . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700

Sequence A Q Y K E Q L A S L M A T L E T T N P H F V R C I I P N N K Q L P A K L E D K V V L D Q L R C N G V L E G I R I T R K G F P N R I I Y A D F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
S
S S
T T
T T T T S

. . . . . . . . . 710 . . . . . . . . . 720 . . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770

Sequence V K R Y Y L L A P N V P R D A E D S Q K A T D A V L K H L N I D P E Q Y R F G I T K I F F R A G Q L A R I E E A R E Q R L G S E Q T K S D Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G G S T T
S
S
T T
T T S
S S
T T

. . . . . . . . . 780 . . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence L K R A N E L V Q W I N D K Q A S L E S R D F G D S I E S V Q S F M N A H K E Y K K T E K P P K G Q E V S E L E A I Y N S L Q T K L R L I K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S S T T T T T T

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900 . . . . . . . . . 910

Sequence R E P F V A P A G L T P N E I D S T W S A L E K A E Q E H A E A L R I E L K R Q K K I A V L L Q K Y N R I L K K L E N W A T T K S V Y L G S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T
S T G G G T G G G

. . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960 . . . . . . . . . 970 . . . . . . . . . 980

Sequence N E T G D S I T A V Q A K L K N L E A F D G E C Q S L E G Q S N S D L L S I L A Q L T E L N Y N G V P E L T E R K D T F F A Q Q W T G V K S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
S T T T T T T T T
T T T T T

. . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . .

Sequence S A E T Y K N T L L A E L E R L Q K I E D L H H H H H H H

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S G G G G T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	N	P	I	H	D	R	T	S	D	Y	H	K	Y	L	K	V	K	Q	G	D	S	D	L	F	K	L	T	V	S	D	K	R	Y	I	W	Y	N	P	D	P	D	E	R	D	S	Y	E	C	G	E	I	V	S	E	T	S	D	S	F	T	F	K	T	V	D	G	Q	D	R	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		G	G	G		T	T	S						S	S					S			S	S		S												S	S	T	T		T	T												S	S							S	S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	V	K	K	D	D	A	N	Q	R	N	P	I	K	F	D	G	V	E	D	M	S	E	L	S	Y	L	N	E	P	A	V	F	H	N	L	R	V	R	Y	N	Q	D	L	I	Y	T	Y	S	G	L	F	L	V	A	V	N	P	F	K	R	I	P	I	Y	T	Q	E	M	V	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T	T			B				G	G	G	T	T		S	B	G	G	G		S	S															T	T	T							T	T								S	S			S			S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	I	F	K	G	R	R	R	N	E	V	A	P	H	I	F	A	I	S	D	V	A	Y	R	S	M	L	D	D	R	Q	N	Q	S	L	L	I	T	G	E	S	G	A	G	K	T	E	N	T	K	K	V	I	Q	Y	L	A	S	V	A	G	R	N	Q	A	N	G	S	G	V	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T	T			T	T	T	S																			T										S	T	T	S	S																	S		T	T		T	T	G	G	G
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	E	Q	Q	I	L	Q	A	N	P	I	L	E	A	F	G	N	A	K	T	T	R	N	N	N	S	S	E	F	G	K	F	I	E	I	Q	F	N	N	A	G	F	I	S	G	A	S	I	Q	S	Y	L	L	E	K	S	R	V	V	F	Q	S	E	T	E	R	N	Y	H	I	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																				S	S		T	T			S	S										T	T	S														G	G	G	G	T				T	T				B
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	Y	Q	L	L	A	G	A	T	A	E	E	K	K	A	L	H	L	A	G	P	E	S	F	N	Y	L	N	Q	S	G	C	V	D	I	K	G	V	S	D	E	D	E	F	K	I	T	R	Q	A	M	D	I	V	G	F	S	Q	E	E	Q	M	S	I	F	K	I	I	A	G	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)													T	T	T	T				G	G	G	S	T	T	T	S	S	S	S					T	T																		T
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	L	H	L	G	N	I	K	F	E	K	G	A	G	E	G	A	V	L	K	D	K	T	A	L	N	A	A	S	T	V	F	G	V	N	P	S	V	L	E	K	A	L	M	E	P	R	I	L	A	G	R	D	L	V	A	Q	H	L	N	V	E	K	S	S	S	S	R	D	A	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												S	S	S	S				S													T	S											S		B				T	T	S			B
	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490
Sequence	V	K	A	L	Y	G	R	L	F	L	W	L	V	K	K	I	N	N	V	L	C	S	E	R	K	A	Y	F	I	G	V	L	D	I	S	G	F	E	I	F	K	V	N	S	F	E	Q	L	C	I	N	Y	T	N	E	K	L	Q	Q	F	F	N	H	H	M	F	K	V	E	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																							S			S															S	S	B
	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
Sequence	E	E	Y	L	K	E	K	I	N	W	T	F	I	D	F	G	L	D	S	Q	A	T	I	D	L	I	D	G	R	Q	P	P	G	I	L	A	L	L	D	E	Q	S	V	F	P	N	A	T	D	N	T	L	I	T	K	L	H	S	H	F	S	K	K	N	A	K	Y	E	E	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					G	G	G										S	S											T	T	T	T										T	T	S	T	T															T	T	S	S	T	T
	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630
Sequence	R	F	S	K	T	E	F	G	V	T	H	Y	A	G	Q	V	M	Y	E	I	Q	D	W	L	E	K	N	K	D	P	L	Q	Q	D	L	E	L	C	F	K	D	S	S	D	N	V	V	T	K	L	F	N	D	P	N	I	A	S	R	A	K	K	G	A	N	F	I	T	V	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S		S	S							T	T								T	T					T	T													T		S	S															S		B		S	S	S	B
	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700
Sequence	A	Q	Y	K	E	Q	L	A	S	L	M	A	T	L	E	T	T	N	P	H	F	V	R	C	I	I	P	N	N	K	Q	L	P	A	K	L	E	D	K	V	V	L	D	Q	L	R	C	N	G	V	L	E	G	I	R	I	T	R	K	G	F	P	N	R	I	I	Y	A	D	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)															T	T	S										S		S	S			T	T														T	T									T	T	S
	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770
Sequence	V	K	R	Y	Y	L	L	A	P	N	V	P	R	D	A	E	D	S	Q	K	A	T	D	A	V	L	K	H	L	N	I	D	P	E	Q	Y	R	F	G	I	T	K	I	F	F	R	A	G	Q	L	A	R	I	E	E	A	R	E	Q	R	L	G	S	E	Q	T	K	S	D	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					G	G	G	S	T	T			S			S													T	T			T	T	S					S	S						T	T
	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	L	K	R	A	N	E	L	V	Q	W	I	N	D	K	Q	A	S	L	E	S	R	D	F	G	D	S	I	E	S	V	Q	S	F	M	N	A	H	K	E	Y	K	K	T	E	K	P	P	K	G	Q	E	V	S	E	L	E	A	I	Y	N	S	L	Q	T	K	L	R	L	I	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																			T						S	S															T	T	T	T																									T	T
	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910
Sequence	R	E	P	F	V	A	P	A	G	L	T	P	N	E	I	D	S	T	W	S	A	L	E	K	A	E	Q	E	H	A	E	A	L	R	I	E	L	K	R	Q	K	K	I	A	V	L	L	Q	K	Y	N	R	I	L	K	K	L	E	N	W	A	T	T	K	S	V	Y	L	G	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S							T	T		S																																																			T	G	G	G	T	G	G	G
	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980
Sequence	N	E	T	G	D	S	I	T	A	V	Q	A	K	L	K	N	L	E	A	F	D	G	E	C	Q	S	L	E	G	Q	S	N	S	D	L	L	S	I	L	A	Q	L	T	E	L	N	Y	N	G	V	P	E	L	T	E	R	K	D	T	F	F	A	Q	Q	W	T	G	V	K	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S	S			S								T	T									T					T														T	T	T	T		T	T												T	T	T
	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.
Sequence	S	A	E	T	Y	K	N	T	L	L	A	E	L	E	R	L	Q	K	I	E	D	L	H	H	H	H	H	H	H
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																							S	G	G	G	G	T