PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2y3aB_

Fold library id	PDB Header	Molecule	Title
c2y3aB_	PDB header: transferase	Chain: B: PDB Molecule: phosphatidylinositol 3-kinase regulatory subunit beta;	PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941

Links to external resources
Added to library: Sat Mar 19 08:53:27 2011

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence K V Y H Q Q Y Q D K S R E Y D Q L Y E E Y T R T S Q E L Q M K R T A I E A F N E T I K I F E E Q G Q T Q E K C S K E Y L G N E K E M Q R I L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
T T T T
T T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence L N S E R L K S R I A E I H E S R T K L E Q D L R A Q A S D N R E I D K R M N S L K P D L M Q L R K I R D Q Y L V W L L P H H E E R T W Y V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T
S
G G G S S T T T B

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence G K I N R T Q A E E M L S G K R D G T F L I R E S S Q R G C Y A C S V V V D G D T K H C V I Y R T A T G F G F A E P Y N L Y G S L K E L V L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T T S
T T B B
S S T T
S S S T T S B T T B
S S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . .

Sequence H Y Q H A S L V Q H N D A L T V T L A H P V R A P G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S S S
S T T T
S S
S B
S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	K	V	Y	H	Q	Q	Y	Q	D	K	S	R	E	Y	D	Q	L	Y	E	E	Y	T	R	T	S	Q	E	L	Q	M	K	R	T	A	I	E	A	F	N	E	T	I	K	I	F	E	E	Q	G	Q	T	Q	E	K	C	S	K	E	Y	L	G	N	E	K	E	M	Q	R	I	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S	S							T	T	T																																											T					T	T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	L	N	S	E	R	L	K	S	R	I	A	E	I	H	E	S	R	T	K	L	E	Q	D	L	R	A	Q	A	S	D	N	R	E	I	D	K	R	M	N	S	L	K	P	D	L	M	Q	L	R	K	I	R	D	Q	Y	L	V	W	L	L	P	H	H	E	E	R	T	W	Y	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																																										T											T	T			S				G	G	G	S	S	T	T	T	B
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	G	K	I	N	R	T	Q	A	E	E	M	L	S	G	K	R	D	G	T	F	L	I	R	E	S	S	Q	R	G	C	Y	A	C	S	V	V	V	D	G	D	T	K	H	C	V	I	Y	R	T	A	T	G	F	G	F	A	E	P	Y	N	L	Y	G	S	L	K	E	L	V	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S											T	T	S		T	T	B			B				S	S	T	T									S	S	S										T	T				S	B	T	T	B				S	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.
Sequence	H	Y	Q	H	A	S	L	V	Q	H	N	D	A	L	T	V	T	L	A	H	P	V	R	A	P	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	S	S	S		S	T	T	T		S	S						S	B		S