PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3hizB_

Fold library id	PDB Header	Molecule	Title
c3hizB_	PDB header: transferase/oncoprotein	Chain: B: PDB Molecule: phosphatidylinositol 3-kinase regulatory subunit	PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha

Links to external resources
Added to library: Sun Aug 29 08:35:03 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence S L Q N A E W Y W G D I S R E E V N E K L R D T A D G T F L V R D A S T K M H G D Y T L T L R K G G N N K L I K I F H R D G K Y G F S D P L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
S S S
S S S
T T
S S
S S
S S S B
G G G
B S S S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence T F S S V V E L I N H Y L A Q Y N P K L D V K L L Y P V S K Y K K L H E Y N T Q F Q E K S R E Y D R L Y E E Y T R T S Q E I Q M K R T A I E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S T
S S
T T
S
S
T T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence A F N E T I K I F E E Q C Q T Q E R Y S K E Y I E K F K R E G N E K E I Q R I M H N Y D K L K S R I S E I I D S R R R L E E D L K K Q A A E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T T T T T T S S
S T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . .

Sequence Y R E I D K R M N S I K P D L I Q L R K T R D Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	S	L	Q	N	A	E	W	Y	W	G	D	I	S	R	E	E	V	N	E	K	L	R	D	T	A	D	G	T	F	L	V	R	D	A	S	T	K	M	H	G	D	Y	T	L	T	L	R	K	G	G	N	N	K	L	I	K	I	F	H	R	D	G	K	Y	G	F	S	D	P	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S	S		S	S				S										S	S	S			T	T								S	S		S	S										S	S	S							B		G	G	G			B	S	S	S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	T	F	S	S	V	V	E	L	I	N	H	Y	L	A	Q	Y	N	P	K	L	D	V	K	L	L	Y	P	V	S	K	Y	K	K	L	H	E	Y	N	T	Q	F	Q	E	K	S	R	E	Y	D	R	L	Y	E	E	Y	T	R	T	S	Q	E	I	Q	M	K	R	T	A	I	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S	S						T				S	S		T	T			S												S		T	T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	A	F	N	E	T	I	K	I	F	E	E	Q	C	Q	T	Q	E	R	Y	S	K	E	Y	I	E	K	F	K	R	E	G	N	E	K	E	I	Q	R	I	M	H	N	Y	D	K	L	K	S	R	I	S	E	I	I	D	S	R	R	R	L	E	E	D	L	K	K	Q	A	A	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																					T	T	T	T	T	T	T	T	T	S	S			S	T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.
Sequence	Y	R	E	I	D	K	R	M	N	S	I	K	P	D	L	I	Q	L	R	K	T	R	D	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)