PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c1quuA_

Fold library id	PDB Header	Molecule	Title
c1quuA_	PDB header: contractile protein	Chain: A: PDB Molecule: human skeletal muscle alpha-actinin 2;	PDBTitle: crystal structure of two central spectrin-like repeats from2 alpha-actinin

Links to external resources
Added to library: Tue Mar 16 12:02:26 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence G S S N E I R R L E R L E H L A E K F R Q K A S T H E T W A Y G K E Q I L L Q K D Y E S A S L T E V R A L L R K H E A F E S D L A A H Q D R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T T T T
S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence V E Q I A A I A Q E L N E L D Y H D A V N V N D R C Q K I C D Q W D R L G T L T Q K R R E A L E R M E K L L E T I D Q L H L E F A K R A A P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence F N N W M E G A M E D L Q D M F I V H S I E E I Q S L I T A H E Q F K A T L P E A D G E R Q S I M A I Q N E V E K V I Q S Y N I R I S S S N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T
S T T T T S
T T S
S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . .

Sequence P Y S T V T M D E L R T K W D K V K Q L V P I R D Q S L Q E E L A R Q H A N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S S
S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	G	S	S	N	E	I	R	R	L	E	R	L	E	H	L	A	E	K	F	R	Q	K	A	S	T	H	E	T	W	A	Y	G	K	E	Q	I	L	L	Q	K	D	Y	E	S	A	S	L	T	E	V	R	A	L	L	R	K	H	E	A	F	E	S	D	L	A	A	H	Q	D	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T	T																									T	T	T											S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	V	E	Q	I	A	A	I	A	Q	E	L	N	E	L	D	Y	H	D	A	V	N	V	N	D	R	C	Q	K	I	C	D	Q	W	D	R	L	G	T	L	T	Q	K	R	R	E	A	L	E	R	M	E	K	L	L	E	T	I	D	Q	L	H	L	E	F	A	K	R	A	A	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														T	T		T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	F	N	N	W	M	E	G	A	M	E	D	L	Q	D	M	F	I	V	H	S	I	E	E	I	Q	S	L	I	T	A	H	E	Q	F	K	A	T	L	P	E	A	D	G	E	R	Q	S	I	M	A	I	Q	N	E	V	E	K	V	I	Q	S	Y	N	I	R	I	S	S	S	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										T	T	T	T							S	T	T	T													T																										S		T	T	S			S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.
Sequence	P	Y	S	T	V	T	M	D	E	L	R	T	K	W	D	K	V	K	Q	L	V	P	I	R	D	Q	S	L	Q	E	E	L	A	R	Q	H	A	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T		S	S																															S