PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4a55B_

Fold library id	PDB Header	Molecule	Title
c4a55B_	PDB header: transferase	Chain: B: PDB Molecule: phosphatidylinositol 3-kinase regulatory subunit alpha;	PDBTitle: crystal structure of p110alpha in complex with ish2 of p85alpha and2 the inhibitor pik-108

Links to external resources
Added to library: Sat Dec 31 16:41:21 2011

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence K L H E Y N T Q F Q E K S R E Y D R L Y E E Y T R T S Q E I Q M K R T A I E A F N E T I K I F E E Q C Q T Q E R Y S K E Y I E K F K R E G N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence E K E I Q R I M H N Y D K L K S R I S E I I D S R R R L E E D L K K Q A A E Y R E I D K R M N S I K P D L I Q L R K T R D Q Y L M K L N E W

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G
T T

.

Sequence L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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Phyre2 is part of Genome3D

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	K	L	H	E	Y	N	T	Q	F	Q	E	K	S	R	E	Y	D	R	L	Y	E	E	Y	T	R	T	S	Q	E	I	Q	M	K	R	T	A	I	E	A	F	N	E	T	I	K	I	F	E	E	Q	C	Q	T	Q	E	R	Y	S	K	E	Y	I	E	K	F	K	R	E	G	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																																																										T											T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	E	K	E	I	Q	R	I	M	H	N	Y	D	K	L	K	S	R	I	S	E	I	I	D	S	R	R	R	L	E	E	D	L	K	K	Q	A	A	E	Y	R	E	I	D	K	R	M	N	S	I	K	P	D	L	I	Q	L	R	K	T	R	D	Q	Y	L	M	K	L	N	E	W
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																																																												G	G	G						T	T
	.
Sequence	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)