Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP43329
DateThu Jan 5 12:02:17 GMT 2012
Unique Job IDfe846714949ca116

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3kx2A_
Top template information
PDB header:hydrolase
Chain: A: PDB Molecule:pre-mrna-splicing factor atp-dependent rna
PDBTitle: crystal structure of prp43p in complex with adp
Confidence and coverage
Confidence:100.0% Coverage: 48%
621 residues ( 48% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MTEQQKLTFTALQQRLDSLMLRDRLRFSRRLHGVKKVKNPDAQQAIFQEMAKEIDQAAGK
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   .........70.........80.........90.........100.........110.........120
Sequence  VLLREAARPEITYPDNLPVSQKKQDILEAIRDHQVVIVAGETGSGKTTQLPKICMELGRG
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   .........130.........140.........150.........160.........170.........180
Sequence  IKGLIGHTQPRRLAARTVANRIAEELKTEPGGCIGYKVRFSDHVSDNTMVKLMTDGILLA
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   .........190.........200.........210.........220.........230.........240
Sequence  EIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLKELLPRRPDLKIIITSATIDPERFSRH
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   .........250.........260.........270.........280.........290.........300
Sequence  FNNAPIIEVSGRTYPVEVRYRPIVEEADDTERDQLQAIFDAVDELSQESHGDILIFMSGE
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   .........310.........320.........330.........340.........350.........360
Sequence  REIRDTADALNKLNLRHTEILPLYARLSNSEQNRVFQSHSGRRIVLATNVAETSLTVPGI
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   .........370.........380.........390.........400.........410.........420
Sequence  KYVIDPGTARISRYSYRTKVQRLPIEPISQASANQRKGRCGRVSEGICIRLYSEDDFLSR
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   .........430.........440.........450.........460.........470.........480
Sequence  PEFTDPEILRTNLASVILQMTALGLGDIAAFPFVEAPDKRNIQDGVRLLEELGAITTDEQ
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   .........490.........500.........510.........520.........530.........540
Sequence  ASAYKLTPLGRQLSQLPVDPRLARMVLEAQKHGCVREAMIITSALSIQDPRERPMDKQQA
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   .........550.........560.........570.........580.........590.........600
Sequence  SDEKHRRFHDKESDFLAFVNLWNYLGEQQKALSSNAFRRLCRTDYLNYLRVREWQDIYTQ
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   .........610.........620.........630.........640.........650.........660
Sequence  LRQVVKELGIPVNSEPAEYREIHIALLTGLLSHIGMKDADKQEYTGARNARFSIFPGSGL
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   .........670.........680.........690.........700.........710.........720
Sequence  FKKPPKWVMVAELVETSRLWGRIAARIDPEWVEPVAQHLIKRTYSEPHWERAQGAVMATE
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   .........730.........740.........750.........760.........770.........780
Sequence  KVTVYGLPIVAARKVNYSQIDPALCRELFIRHALVEGDWQTRHAFFRENLKLRAEVEELE
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   .........790.........800.........810.........820.........830.........840
Sequence  HKSRRRDILVDDETLFEFYDQRISHDVISARHFDSWWKKVSRETPDLLNFEKSMLIKEGA
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   .........850.........860.........870.........880.........890.........900
Sequence  EKISKLDYPNFWHQGNLKLRLSYQFEPGADADGVTVHIPLPLLNQVEESGFEWQIPGLRR
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   .........910.........920.........930.........940.........950.........960
Sequence  ELVIALIKSLPKPVRRNFVPAPNYAEAFLGRVKPLELPLLDSLERELRRMTGVTVDREDW
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   .........970.........980.........990.........1000.........1010.........1020
Sequence  HWDQVPDHLKITFRVVDDKNKKLKEGRSLQDLKDALKGKVQETLSAVADDGIEQSGLHIW
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   .........1030.........1040.........1050.........1060.........1070.........1080
Sequence  SFGQLPESYEQKRGNYKVKAWPALVDERDSVAIKLFDNPLEQKQAMWNGLRRLLLLNIPS
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   .........1090.........1100.........1110.........1120.........1130.........1140
Sequence  PIKYLHEKLPNKAKLGLYFNPYGKVLELIDDCISCGVDKLIDANGGPVWTEEGFAALHEK
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   .........1150.........1160.........1170.........1180.........1190.........1200
Sequence  VRAELNDTVVDIAKQVEQILTAVFNINKRLKGRVDMTMALGLSDIKAQMGGLVYRGFVTG
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   .........1210.........1220.........1230.........1240.........1250.........1260
Sequence  NGFKRLGDTLRYLQAIEKRLEKLAVDPHRDRAQMLKVENVQQAWQQWINKLPPARREDED
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   .........1270.........1280.........1290.........1300
Sequence  VKEIRWMIEELRVSYFAQQLGTPYPISDKRILQAMEQISG
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3kx2 chain A

3D model

Region: 73 - 707
Aligned: 621
Modelled: 635
Confidence: 100.0%
Identity: 37%
PDB header:hydrolase
Chain: A: PDB Molecule:pre-mrna-splicing factor atp-dependent rna
PDBTitle: crystal structure of prp43p in complex with adp

Phyre2

PDB 1cu1 chain B

3D model

Region: 91 - 541
Aligned: 404
Modelled: 426
Confidence: 100.0%
Identity: 20%
PDB header:hydrolase
Chain: B: PDB Molecule:protein (protease/helicase ns3);
PDBTitle: crystal structure of an enzyme complex from hepatitis c2 virus

Phyre2

PDB 1a1v chain A

3D model

Region: 91 - 557
Aligned: 415
Modelled: 446
Confidence: 100.0%
Identity: 18%
PDB header:hydrolase/dna
Chain: A: PDB Molecule:protein (ns3 protein);
PDBTitle: hepatitis c virus ns3 helicase domain complexed with single2 stranded sdna

Phyre2

PDB 2f55 chain C

3D model

Region: 91 - 557
Aligned: 414
Modelled: 444
Confidence: 100.0%
Identity: 18%
PDB header:hydrolase/dna
Chain: C: PDB Molecule:polyprotein;
PDBTitle: two hepatitis c virus ns3 helicase domains complexed with2 the same strand of dna

Phyre2

PDB 2vbc chain A

3D model

Region: 90 - 552
Aligned: 419
Modelled: 442
Confidence: 100.0%
Identity: 20%
PDB header:hydrolase
Chain: A: PDB Molecule:dengue 4 ns3 full-length protein;
PDBTitle: crystal structure of the ns3 protease-helicase from dengue2 virus

Phyre2

PDB 2wv9 chain A

3D model

Region: 88 - 509
Aligned: 366
Modelled: 386
Confidence: 100.0%
Identity: 19%
PDB header:hydrolase
Chain: A: PDB Molecule:flavivirin protease ns2b regulatory subunit, flavivirin
PDBTitle: crystal structure of the ns3 protease-helicase from murray2 valley encephalitis virus

Phyre2

PDB 1ymf chain A

3D model

Region: 89 - 570
Aligned: 426
Modelled: 473
Confidence: 100.0%
Identity: 16%
PDB header:hydrolase
Chain: A: PDB Molecule:genome polyprotein [contains: flavivirin
PDBTitle: crystal structure of yellow fever virus ns3 helicase2 complexed with adp

Phyre2

PDB 3i4u chain A

3D model

Region: 458 - 701
Aligned: 233
Modelled: 244
Confidence: 100.0%
Identity: 29%
PDB header:hydrolase
Chain: A: PDB Molecule:atp-dependent rna helicase dhx8;
PDBTitle: crystal structure analysis of a helicase associated domain

Phyre2

PDB 2jlr chain A

3D model

Region: 88 - 515
Aligned: 384
Modelled: 405
Confidence: 100.0%
Identity: 18%
PDB header:hydrolase
Chain: A: PDB Molecule:serine protease subunit ns3;
PDBTitle: dengue virus 4 ns3 helicase in complex with amppnp

Phyre2

PDB 3rc8 chain A

3D model

Region: 92 - 601
Aligned: 440
Modelled: 467
Confidence: 100.0%
Identity: 17%
PDB header:hydrolase/rna
Chain: A: PDB Molecule:atp-dependent rna helicase supv3l1, mitochondrial;
PDBTitle: human mitochondrial helicase suv3 in complex with short rna fragment

Phyre2

PDB 2z83 chain A

3D model

Region: 88 - 515
Aligned: 378
Modelled: 411
Confidence: 100.0%
Identity: 18%
PDB header:viral protein
Chain: A: PDB Molecule:helicase/nucleoside triphosphatase;
PDBTitle: crystal structure of catalytic domain of japanese2 encephalitis virus ns3 helicase/nucleoside triphosphatase3 at a resolution 1.8

Phyre2

PDB 8ohm chain A domain 2

3D model

Region: 285 - 557
Aligned: 258
Modelled: 273
Confidence: 100.0%
Identity: 19%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: RNA helicase

Phyre2

PDB 3llm chain B

3D model

Region: 37 - 249
Aligned: 211
Modelled: 213
Confidence: 100.0%
Identity: 36%
PDB header:hydrolase
Chain: B: PDB Molecule:atp-dependent rna helicase a;
PDBTitle: crystal structure analysis of a rna helicase

Phyre2

PDB 2v6j chain A

3D model

Region: 94 - 428
Aligned: 291
Modelled: 325
Confidence: 100.0%
Identity: 21%
PDB header:hydrolase
Chain: A: PDB Molecule:rna helicase;
PDBTitle: kokobera virus helicase: mutant met47thr

Phyre2

PDB 1yks chain A domain 2

3D model

Region: 284 - 559
Aligned: 247
Modelled: 276
Confidence: 100.0%
Identity: 19%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: RNA helicase

Phyre2

PDB 2va8 chain A

3D model

Region: 80 - 610
Aligned: 505
Modelled: 510
Confidence: 100.0%
Identity: 15%
PDB header:hydrolase
Chain: A: PDB Molecule:ski2-type helicase;
PDBTitle: dna repair helicase hel308

Phyre2

PDB 2p6u chain A

3D model

Region: 85 - 608
Aligned: 495
Modelled: 510
Confidence: 100.0%
Identity: 20%
PDB header:dna binding protein
Chain: A: PDB Molecule:afuhel308 helicase;
PDBTitle: apo structure of the hel308 superfamily 2 helicase

Phyre2

PDB 2qeq chain A

3D model

Region: 94 - 515
Aligned: 369
Modelled: 419
Confidence: 100.0%
Identity: 18%
PDB header:hydrolase
Chain: A: PDB Molecule:flavivirin protease ns3 catalytic subunit;
PDBTitle: crystal structure of kunjin virus ns3 helicase

Phyre2

PDB 2zj2 chain A

3D model

Region: 80 - 608
Aligned: 510
Modelled: 529
Confidence: 100.0%
Identity: 20%
PDB header:hydrolase
Chain: A: PDB Molecule:putative ski2-type helicase;
PDBTitle: archaeal dna helicase hjm apo state in form 1

Phyre2

PDB 4a4z chain A

3D model

Region: 67 - 413
Aligned: 322
Modelled: 345
Confidence: 100.0%
Identity: 22%
PDB header:hydrolase
Chain: A: PDB Molecule:antiviral helicase ski2;
PDBTitle: crystal structure of the s. cerevisiae dexh helicase ski2 bound to2 amppnp

Phyre2
1

c3kx2A_
2

c1cu1B_
3

c1a1vA_
4

c2f55C_
5

c2vbcA_
6

c2wv9A_
7

c1ymfA_
8

c3i4uA_
9

c2jlrA_
10

c3rc8A_
11

c2z83A_
12

d8ohma2
13

c3llmB_
14

c2v6jA_
15

d1yksa2
16

c2va8A_
17

c2p6uA_
18

c2qeqA_
19

c2zj2A_
20

c4a4zA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3kx2A_



100.0 37 PDB header:hydrolase
Chain: A: PDB Molecule:pre-mrna-splicing factor atp-dependent rna
PDBTitle: crystal structure of prp43p in complex with adp
2c1cu1B_



100.0 20 PDB header:hydrolase
Chain: B: PDB Molecule:protein (protease/helicase ns3);
PDBTitle: crystal structure of an enzyme complex from hepatitis c2 virus
3c1a1vA_



100.0 18 PDB header:hydrolase/dna
Chain: A: PDB Molecule:protein (ns3 protein);
PDBTitle: hepatitis c virus ns3 helicase domain complexed with single2 stranded sdna
4c2f55C_



100.0 18 PDB header:hydrolase/dna
Chain: C: PDB Molecule:polyprotein;
PDBTitle: two hepatitis c virus ns3 helicase domains complexed with2 the same strand of dna
5c2vbcA_



100.0 20 PDB header:hydrolase
Chain: A: PDB Molecule:dengue 4 ns3 full-length protein;
PDBTitle: crystal structure of the ns3 protease-helicase from dengue2 virus
6c2wv9A_



100.0 19 PDB header:hydrolase
Chain: A: PDB Molecule:flavivirin protease ns2b regulatory subunit, flavivirin
PDBTitle: crystal structure of the ns3 protease-helicase from murray2 valley encephalitis virus
7c1ymfA_



100.0 16 PDB header:hydrolase
Chain: A: PDB Molecule:genome polyprotein [contains: flavivirin
PDBTitle: crystal structure of yellow fever virus ns3 helicase2 complexed with adp
8c3i4uA_



100.0 29 PDB header:hydrolase
Chain: A: PDB Molecule:atp-dependent rna helicase dhx8;
PDBTitle: crystal structure analysis of a helicase associated domain
9c2jlrA_



100.0 18 PDB header:hydrolase
Chain: A: PDB Molecule:serine protease subunit ns3;
PDBTitle: dengue virus 4 ns3 helicase in complex with amppnp
10c3rc8A_



100.0 17 PDB header:hydrolase/rna
Chain: A: PDB Molecule:atp-dependent rna helicase supv3l1, mitochondrial;
PDBTitle: human mitochondrial helicase suv3 in complex with short rna fragment
11c2z83A_



100.0 18 PDB header:viral protein
Chain: A: PDB Molecule:helicase/nucleoside triphosphatase;
PDBTitle: crystal structure of catalytic domain of japanese2 encephalitis virus ns3 helicase/nucleoside triphosphatase3 at a resolution 1.8
12d8ohma2



100.0 19 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:RNA helicase
13c3llmB_



100.0 36 PDB header:hydrolase
Chain: B: PDB Molecule:atp-dependent rna helicase a;
PDBTitle: crystal structure analysis of a rna helicase
14c2v6jA_



100.0 21 PDB header:hydrolase
Chain: A: PDB Molecule:rna helicase;
PDBTitle: kokobera virus helicase: mutant met47thr
15d1yksa2



100.0 19 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:RNA helicase
16c2va8A_



100.0 15 PDB header:hydrolase
Chain: A: PDB Molecule:ski2-type helicase;
PDBTitle: dna repair helicase hel308
17c2p6uA_



100.0 20 PDB header:dna binding protein
Chain: A: PDB Molecule:afuhel308 helicase;
PDBTitle: apo structure of the hel308 superfamily 2 helicase
18c2qeqA_



100.0 18 PDB header:hydrolase
Chain: A: PDB Molecule:flavivirin protease ns3 catalytic subunit;
PDBTitle: crystal structure of kunjin virus ns3 helicase
19c2zj2A_



100.0 20 PDB header:hydrolase
Chain: A: PDB Molecule:putative ski2-type helicase;
PDBTitle: archaeal dna helicase hjm apo state in form 1
20c4a4zA_



100.0 22 PDB header:hydrolase
Chain: A: PDB Molecule:antiviral helicase ski2;
PDBTitle: crystal structure of the s. cerevisiae dexh helicase ski2 bound to2 amppnp
21c3bxzA_



not modelled 100.0 15 PDB header:transport protein
Chain: A: PDB Molecule:preprotein translocase subunit seca;
PDBTitle: crystal structure of the isolated dead motor domains from2 escherichia coli seca
22c2xgjA_



not modelled 100.0 20 PDB header:hydrolase/rna
Chain: A: PDB Molecule:atp-dependent rna helicase dob1;
PDBTitle: structure of mtr4, a dexh helicase involved in nuclear rna2 processing and surveillance
23d2bmfa2



not modelled 100.0 19 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:RNA helicase
24c2v1xB_



not modelled 99.9 18 PDB header:hydrolase
Chain: B: PDB Molecule:atp-dependent dna helicase q1;
PDBTitle: crystal structure of human recq-like dna helicase
25c3l9oA_



not modelled 99.9 22 PDB header:hydrolase
Chain: A: PDB Molecule:atp-dependent rna helicase dob1;
PDBTitle: crystal structure of mtr4, a co-factor of the nuclear exosome
26c1gm5A_



not modelled 99.9 17 PDB header:helicase
Chain: A: PDB Molecule:recg;
PDBTitle: structure of recg bound to three-way dna junction
27c3ewsA_



not modelled 99.9 14 PDB header:hydrolase
Chain: A: PDB Molecule:atp-dependent rna helicase ddx19b;
PDBTitle: human dead-box rna-helicase ddx19 in complex with adp
28c1oywA_



not modelled 99.9 20 PDB header:hydrolase
Chain: A: PDB Molecule:atp-dependent dna helicase;
PDBTitle: structure of the recq catalytic core
29c2eyqA_



not modelled 99.9 18 PDB header:hydrolase
Chain: A: PDB Molecule:transcription-repair coupling factor;
PDBTitle: crystal structure of escherichia coli transcription-repair2 coupling factor
30c2db3D_



not modelled 99.9 20 PDB header:hydrolase/rna
Chain: D: PDB Molecule:atp-dependent rna helicase vasa;
PDBTitle: structural basis for rna unwinding by the dead-box protein2 drosophila vasa
31c3fhtA_



not modelled 99.9 14 PDB header:hydrolase/rna
Chain: A: PDB Molecule:atp-dependent rna helicase ddx19b;
PDBTitle: crystal structure of human dbp5 in complex with amppnp and rna
32c2fsgA_



not modelled 99.9 19 PDB header:protein transport
Chain: A: PDB Molecule:preprotein translocase seca subunit;
PDBTitle: complex seca:atp from escherichia coli
33c1xtkA_



not modelled 99.9 16 PDB header:gene regulation
Chain: A: PDB Molecule:probable atp-dependent rna helicase p47;
PDBTitle: structure of decd to dead mutation of human uap56
34c3pexA_



not modelled 99.8 17 PDB header:hydrolase
Chain: A: PDB Molecule:atp-dependent rna helicase dbp5;
PDBTitle: s. cerevisiae dbp5 l327v bound to gle1 h337r and ip6
35c3i5yA_



not modelled 99.8 17 PDB header:hydrolase/rna
Chain: A: PDB Molecule:atp-dependent rna helicase mss116;
PDBTitle: structure of mss116p bound to ssrna containing a single 5-bru and amp-2 pnp
36c1hv8B_



not modelled 99.8 22 PDB header:rna binding protein
Chain: B: PDB Molecule:putative atp-dependent rna helicase mj0669;
PDBTitle: crystal structure of a dead box protein from the2 hyperthermophile methanococcus jannaschii
37c1gl9B_



not modelled 99.8 19 PDB header:topoisomerase
Chain: B: PDB Molecule:reverse gyrase;
PDBTitle: archaeoglobus fulgidus reverse gyrase complexed with adpnp
38c1s2mA_



not modelled 99.8 18 PDB header:rna binding protein
Chain: A: PDB Molecule:putative atp-dependent rna helicase dhh1;
PDBTitle: crystal structure of the dead box protein dhh1p
39c2z0mA_



not modelled 99.8 22 PDB header:rna binding protein
Chain: A: PDB Molecule:337aa long hypothetical atp-dependent rna
PDBTitle: crystal structure of hypothetical atp-dependent rna2 helicase from sulfolobus tokodaii
40c3tmiA_



not modelled 99.8 19 PDB header:hydrolase/rna
Chain: A: PDB Molecule:atp-dependent rna helicase ddx58;
PDBTitle: structural basis for rna recognition and activation of rig-i
41c2ocaA_



not modelled 99.8 12 PDB header:hydrolase
Chain: A: PDB Molecule:atp-dependent dna helicase uvsw;
PDBTitle: the crystal structure of t4 uvsw
42c2vsxA_



not modelled 99.8 17 PDB header:translation/hydrolase
Chain: A: PDB Molecule:atp-dependent rna helicase eif4a;
PDBTitle: crystal structure of a translation initiation complex
43c1wp9D_



not modelled 99.8 20 PDB header:hydrolase
Chain: D: PDB Molecule:atp-dependent rna helicase, putative;
PDBTitle: crystal structure of pyrococcus furiosus hef helicase domain
44c1c4oA_



not modelled 99.8 21 PDB header:replication
Chain: A: PDB Molecule:dna nucleotide excision repair enzyme uvrb;
PDBTitle: crystal structure of the dna nucleotide excision repair enzyme uvrb2 from thermus thermophilus
45c2i4iA_



not modelled 99.8 17 PDB header:hydrolase
Chain: A: PDB Molecule:atp-dependent rna helicase ddx3x;
PDBTitle: crystal structure of human dead-box rna helicase ddx3x
46d1a1va1



not modelled 99.8 22 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:RNA helicase
47c2hxyC_



not modelled 99.7 17 PDB header:hydrolase
Chain: C: PDB Molecule:probable atp-dependent rna helicase ddx48;
PDBTitle: crystal structure of human apo-eif4aiii
48c2fwrA_



not modelled 99.7 22 PDB header:dna binding protein
Chain: A: PDB Molecule:dna repair protein rad25;
PDBTitle: structure of archaeoglobus fulgidis xpb
49c3h1tA_



not modelled 99.7 20 PDB header:hydrolase
Chain: A: PDB Molecule:type i site-specific restriction-modification
PDBTitle: the fragment structure of a putative hsdr subunit of a type2 i restriction enzyme from vibrio vulnificus yj016
50d1a1va2



not modelled 99.7 21 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:RNA helicase
51d1yksa1



not modelled 99.7 18 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:RNA helicase
52c3oiyB_



not modelled 99.6 17 PDB header:isomerase
Chain: B: PDB Molecule:reverse gyrase helicase domain;
PDBTitle: helicase domain of reverse gyrase from thermotoga maritima
53c3tbkA_



not modelled 99.6 18 PDB header:hydrolase
Chain: A: PDB Molecule:rig-i helicase domain;
PDBTitle: mouse rig-i atpase domain
54c1tf2A_



not modelled 99.6 22 PDB header:protein transport
Chain: A: PDB Molecule:preprotein translocase seca subunit;
PDBTitle: crystal structure of seca:adp in an open conformation from2 bacillus subtilis
55c2j7pA_



not modelled 99.6 21 PDB header:signal recognition
Chain: A: PDB Molecule:signal recognition particle protein;
PDBTitle: gmppnp-stabilized ng domain complex of the srp gtpases ffh2 and ftsy
56d2p6ra3



not modelled 99.6 15 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
57c3crw1_



not modelled 99.6 19 PDB header:hydrolase
Chain: 1: PDB Molecule:xpd/rad3 related dna helicase;
PDBTitle: "xpd_apo"
58d1gkub1



not modelled 99.5 20 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Helicase-like "domain" of reverse gyrase
59c3dl8B_



not modelled 99.5 21 PDB header:protein transport
Chain: B: PDB Molecule:protein translocase subunit seca;
PDBTitle: structure of the complex of aquifex aeolicus secyeg and2 bacillus subtilis seca
60c2vl7A_



not modelled 99.5 19 PDB header:unknown function
Chain: A: PDB Molecule:xpd;
PDBTitle: structure of s. tokodaii xpd4
61c2cnwF_



not modelled 99.5 20 PDB header:signal recognition
Chain: F: PDB Molecule:cell division protein ftsy;
PDBTitle: gdpalf4 complex of the srp gtpases ffh and ftsy
62d1gl9b1



not modelled 99.5 20 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Helicase-like "domain" of reverse gyrase
63d2eyqa5



not modelled 99.4 18 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
64c2d7dA_



not modelled 99.4 19 PDB header:hydrolase/dna
Chain: A: PDB Molecule:uvrabc system protein b;
PDBTitle: structural insights into the cryptic dna dependent atp-ase2 activity of uvrb
65c2w74B_



not modelled 99.4 13 PDB header:hydrolase
Chain: B: PDB Molecule:type i restriction enzyme ecor124ii r protein;
PDBTitle: mutant (k220r) of the hsdr subunit of the ecor124i2 restriction enzyme in complex with atp
66d2p6ra4



not modelled 99.4 31 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
67d1q0ua_



not modelled 99.4 17 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
68c3b6eA_



not modelled 99.3 18 PDB header:hydrolase
Chain: A: PDB Molecule:interferon-induced helicase c domain-containing protein 1;
PDBTitle: crystal structure of human dech-box rna helicase mda5 (melanoma2 differentiation-associated protein 5), dech-domain
69c2px0D_



not modelled 99.3 24 PDB header:biosynthetic protein
Chain: D: PDB Molecule:flagellar biosynthesis protein flhf;
PDBTitle: crystal structure of flhf complexed with gmppnp/mg(2+)
70c3fhcB_



not modelled 99.3 16 PDB header:transport protein/hydrolase
Chain: B: PDB Molecule:atp-dependent rna helicase ddx19b;
PDBTitle: crystal structure of human dbp5 in complex with nup214
71c3fmoB_



not modelled 99.3 16 PDB header:oncoprotein/hydrolase
Chain: B: PDB Molecule:atp-dependent rna helicase ddx19b;
PDBTitle: crystal structure of the nucleoporin nup214 in complex with the dead-2 box helicase ddx19
72d2eyqa3



not modelled 99.3 15 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
73d1c4oa2



not modelled 99.2 14 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
74d2g9na1



not modelled 99.2 18 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
75d1wp9a1



not modelled 99.2 17 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
76c3dkpA_



not modelled 99.2 16 PDB header:hydrolase
Chain: A: PDB Molecule:probable atp-dependent rna helicase ddx52;
PDBTitle: human dead-box rna-helicase ddx52, conserved domain i in complex with2 adp
77d1t6na_



not modelled 99.2 15 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
78c2kbeA_



not modelled 99.2 19 PDB header:hydrolase
Chain: A: PDB Molecule:atp-dependent rna helicase dbp5;
PDBTitle: solution structure of amino-terminal domain of dbp5p
79c3ly5A_



not modelled 99.2 20 PDB header:hydrolase
Chain: A: PDB Molecule:atp-dependent rna helicase ddx18;
PDBTitle: ddx18 dead-domain
80c3fmpD_



not modelled 99.2 16 PDB header:oncoprotein/hydrolase
Chain: D: PDB Molecule:atp-dependent rna helicase ddx19b;
PDBTitle: crystal structure of the nucleoporin nup214 in complex with the dead-2 box helicase ddx19
81d1veca_



not modelled 99.2 19 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
82d1qdea_



not modelled 99.1 18 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
83d1t5la2



not modelled 99.1 17 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
84d1s2ma1



not modelled 99.1 18 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
85d1hv8a1



not modelled 99.1 20 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
86d2j0sa2



not modelled 99.1 20 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
87d1oywa3



not modelled 99.1 22 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
88d1gm5a4



not modelled 99.1 26 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
89c2j289_



not modelled 99.1 24 PDB header:ribosome
Chain: 9: PDB Molecule:signal recognition particle 54;
PDBTitle: model of e. coli srp bound to 70s rncs
90c2oxcA_



not modelled 99.1 16 PDB header:hydrolase
Chain: A: PDB Molecule:probable atp-dependent rna helicase ddx20;
PDBTitle: human dead-box rna helicase ddx20, dead domain in complex2 with adp
91d1jr6a_



not modelled 99.1 28 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:RNA helicase
92c2qy9A_



not modelled 99.1 18 PDB header:protein transport
Chain: A: PDB Molecule:cell division protein ftsy;
PDBTitle: structure of the ng+1 construct of the e. coli srp receptor2 ftsy
93d1s2ma2



not modelled 99.1 23 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
94c1vmaA_



not modelled 99.1 21 PDB header:protein transport
Chain: A: PDB Molecule:cell division protein ftsy;
PDBTitle: crystal structure of cell division protein ftsy (tm0570) from2 thermotoga maritima at 1.60 a resolution
95c2p6nA_



not modelled 99.1 23 PDB header:hydrolase
Chain: A: PDB Molecule:atp-dependent rna helicase ddx41;
PDBTitle: human dead-box rna helicase ddx41, helicase domain
96d1rifa_



not modelled 99.0 11 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:DNA helicase UvsW
97c2pl3A_



not modelled 99.0 18 PDB header:hydrolase
Chain: A: PDB Molecule:probable atp-dependent rna helicase ddx10;
PDBTitle: human dead-box rna helicase ddx10, dead domain in complex with adp
98c1z3iX_



not modelled 99.0 17 PDB header:recombination/dna binding
Chain: X: PDB Molecule:similar to rad54-like;
PDBTitle: structure of the swi2/snf2 chromatin remodeling domain of eukaryotic2 rad54
99c2gxqA_



not modelled 99.0 20 PDB header:hydrolase
Chain: A: PDB Molecule:heat resistant rna dependent atpase;
PDBTitle: hera n-terminal domain in complex with amp, crystal form 1
100d2j0sa1



not modelled 99.0 20 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
101c2yhsA_



not modelled 99.0 19 PDB header:cell cycle
Chain: A: PDB Molecule:cell division protein ftsy;
PDBTitle: structure of the e. coli srp receptor ftsy
102c3mwyW_



not modelled 99.0 17 PDB header:hydrolase
Chain: W: PDB Molecule:chromo domain-containing protein 1;
PDBTitle: crystal structure of the chromodomain-atpase portion of the yeast chd12 chromatin remodeler
103c1zu4A_



not modelled 99.0 21 PDB header:protein transport
Chain: A: PDB Molecule:ftsy;
PDBTitle: crystal structure of ftsy from mycoplasma mycoides- space2 group p21212
104d1hv8a2



not modelled 99.0 24 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
105c3iuyB_



not modelled 99.0 22 PDB header:hydrolase
Chain: B: PDB Molecule:probable atp-dependent rna helicase ddx53;
PDBTitle: crystal structure of ddx53 dead-box domain
106d1ls1a2



not modelled 99.0 20 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nitrogenase iron protein-like
107c3b9qA_



not modelled 99.0 22 PDB header:protein transport
Chain: A: PDB Molecule:chloroplast srp receptor homolog, alpha subunit
PDBTitle: the crystal structure of cpftsy from arabidopsis thaliana
108d1wrba1



not modelled 99.0 18 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
109c3earA_



not modelled 98.9 28 PDB header:hydrolase
Chain: A: PDB Molecule:hera;
PDBTitle: novel dimerization motif in the dead box rna helicase hera: form 1,2 partial dimer
110c3berA_



not modelled 98.9 24 PDB header:hydrolase
Chain: A: PDB Molecule:probable atp-dependent rna helicase ddx47;
PDBTitle: human dead-box rna-helicase ddx47, conserved domain i in complex with2 amp
111d2fwra2



not modelled 98.9 19 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
112d1t5ia_



not modelled 98.9 19 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
113d1oywa2



not modelled 98.9 18 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
114c2og2A_



not modelled 98.9 18 PDB header:protein transport
Chain: A: PDB Molecule:putative signal recognition particle receptor;
PDBTitle: crystal structure of chloroplast ftsy from arabidopsis2 thaliana
115d1tf5a4



not modelled 98.9 20 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
116d1wp9a2



not modelled 98.9 21 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
117c3dmqA_



not modelled 98.9 18 PDB header:hydrolase
Chain: A: PDB Molecule:rna polymerase-associated protein rapa;
PDBTitle: crystal structure of rapa, a swi2/snf2 protein that2 recycles rna polymerase during transcription
118c2hjvB_



not modelled 98.9 23 PDB header:hydrolase
Chain: B: PDB Molecule:atp-dependent rna helicase dbpa;
PDBTitle: structure of the second domain (residues 207-368) of the2 bacillus subtilis yxin protein
119d1gm5a3



not modelled 98.9 18 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain
120d2g2ja1



not modelled 98.9 15 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Tandem AAA-ATPase domain

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0