Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	S	Q	L	T	D	A	F	A	R	K	F	Y	Y	L	R	L	S	I	T	D	V	C	N	F	R	C	T	Y	C	L	P	D	G	Y	K	P	S	G	V	T	N	K	G	F	L	T	V	D	E	I	R	R	V	T	R	A	F	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																													?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	L	G	T	E	K	V	R	L	T	G	G	E	P	S	L	R	R	D	F	T	D	I	I	A	A	V	R	E	N	D	A	I	R	Q	I	A	V	T	T	N	G	Y	R	L	E	R	D	V	A	S	W	R	D	A	G	L	T	G	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		N	V	S	V	D	S	L	D	A	R	Q	F	H	A	I	T	G	Q	D	K	F	N	Q	V	M	A	G	I	D	A	A	F	E	A	G	F	E	K	V	K	V	N	T	V	L	M	R	D	V	N	H	H	Q	L	D	T	F	L	N	W
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		I	Q	H	R	P	I	Q	L	R	F	I	E	L	M	E	T	G	E	G	S	E	L	F	R	K	H	H	I	S	G	Q	V	L	R	D	E	L	L	R	R	G	W	I	H	Q	L	R	Q	R	S	D	G	P	A	Q	V	F	C	H	P
Secondary structure
SS confidence
Disorder																									?		?	?																					?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		D	Y	A	G	E	I	G	L	I	M	P	Y	E	K	D	F	C	A	T	C	N	R	L	R	V	S	S	I	G	K	L	H	L	C	L	F	G	E	G	G	V	N	L	R	D	L	L	E	D	D	T	Q	Q	Q	A	L	E	A	R	I
Secondary structure
SS confidence
Disorder																																									?	?		?								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.
Sequence		S	A	A	L	R	E	K	K	Q	T	H	F	L	H	Q	N	N	T	G	I	T	Q	N	L	S	Y	I	G	G
Secondary structure
SS confidence
Disorder										?	?	?	?	?	?	?	?	?	?	?	?	?		?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1tv8 chain A Region: 3 - 311 Aligned: 308 Modelled: 309 Confidence: 100.0% Identity: 32% Fold: TIM beta/alpha-barrel Superfamily: Radical SAM enzymes Family: MoCo biosynthesis proteins Phyre2 PDB 2yx0 chain A Region: 18 - 228 Aligned: 205 Modelled: 207 Confidence: 99.9% Identity: 16% PDB header:metal binding protein Chain: A: PDB Molecule:radical sam enzyme; PDBTitle: crystal structure of p. horikoshii tyw1 Phyre2 PDB 3c8f chain A Region: 9 - 222 Aligned: 210 Modelled: 213 Confidence: 99.8% Identity: 12% PDB header:oxidoreductase Chain: A: PDB Molecule:pyruvate formate-lyase 1-activating enzyme; PDBTitle: 4fe-4s-pyruvate formate-lyase activating enzyme with2 partially disordered adomet Phyre2 PDB 1r30 chain A Region: 15 - 218 Aligned: 201 Modelled: 204 Confidence: 99.8% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:biotin synthase; PDBTitle: the crystal structure of biotin synthase, an s-2 adenosylmethionine-dependent radical enzyme Phyre2 PDB 1r30 chain A Region: 15 - 218 Aligned: 201 Modelled: 204 Confidence: 99.8% Identity: 17% Fold: TIM beta/alpha-barrel Superfamily: Radical SAM enzymes Family: Biotin synthase Phyre2 PDB 3t7v chain A Region: 9 - 218 Aligned: 206 Modelled: 210 Confidence: 99.8% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:methylornithine synthase pylb; PDBTitle: crystal structure of methylornithine synthase (pylb) Phyre2 PDB 2a5h chain C Region: 3 - 272 Aligned: 249 Modelled: 270 Confidence: 99.8% Identity: 18% PDB header:isomerase Chain: C: PDB Molecule:l-lysine 2,3-aminomutase; PDBTitle: 2.1 angstrom x-ray crystal structure of lysine-2,3-aminomutase from2 clostridium subterminale sb4, with michaelis analog (l-alpha-lysine3 external aldimine form of pyridoxal-5'-phosphate). Phyre2 PDB 3cix chain A Region: 9 - 218 Aligned: 206 Modelled: 210 Confidence: 99.7% Identity: 14% PDB header:adomet binding protein Chain: A: PDB Molecule:fefe-hydrogenase maturase; PDBTitle: x-ray structure of the [fefe]-hydrogenase maturase hyde from2 thermotoga maritima in complex with thiocyanate Phyre2 PDB 3rfa chain A Region: 15 - 221 Aligned: 201 Modelled: 207 Confidence: 99.7% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:ribosomal rna large subunit methyltransferase n; PDBTitle: x-ray structure of rlmn from escherichia coli in complex with s-2 adenosylmethionine Phyre2 PDB 2z2u chain A Region: 24 - 243 Aligned: 202 Modelled: 207 Confidence: 99.5% Identity: 15% PDB header:metal binding protein Chain: A: PDB Molecule:upf0026 protein mj0257; PDBTitle: crystal structure of archaeal tyw1 Phyre2 PDB 1olt chain A Region: 3 - 206 Aligned: 203 Modelled: 204 Confidence: 99.5% Identity: 13% Fold: TIM beta/alpha-barrel Superfamily: Radical SAM enzymes Family: Oxygen-independent coproporphyrinogen III oxidase HemN Phyre2 PDB 3can chain A Region: 67 - 222 Aligned: 149 Modelled: 156 Confidence: 99.5% Identity: 17% PDB header:lyase activator Chain: A: PDB Molecule:pyruvate-formate lyase-activating enzyme; PDBTitle: crystal structure of a domain of pyruvate-formate lyase-activating2 enzyme from bacteroides vulgatus atcc 8482 Phyre2 PDB 2qgq chain F Region: 28 - 221 Aligned: 190 Modelled: 194 Confidence: 99.1% Identity: 9% PDB header:structural genomics, unknown function Chain: F: PDB Molecule:protein tm_1862; PDBTitle: crystal structure of tm_1862 from thermotoga maritima.2 northeast structural genomics consortium target vr77 Phyre2 PDB 3ivu chain B Region: 43 - 192 Aligned: 145 Modelled: 150 Confidence: 97.4% Identity: 12% PDB header:transferase Chain: B: PDB Molecule:homocitrate synthase, mitochondrial; PDBTitle: homocitrate synthase lys4 bound to 2-og Phyre2 PDB 3eeg chain B Region: 42 - 192 Aligned: 148 Modelled: 151 Confidence: 95.6% Identity: 14% PDB header:transferase Chain: B: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of a 2-isopropylmalate synthase from2 cytophaga hutchinsonii Phyre2 PDB 3ewb chain X Region: 38 - 192 Aligned: 152 Modelled: 155 Confidence: 95.0% Identity: 9% PDB header:transferase Chain: X: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of n-terminal domain of putative 2-2 isopropylmalate synthase from listeria monocytogenes Phyre2 PDB 2ftp chain A Region: 43 - 192 Aligned: 149 Modelled: 150 Confidence: 92.7% Identity: 13% PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa Phyre2 PDB 1nvm chain G Region: 44 - 192 Aligned: 136 Modelled: 137 Confidence: 91.6% Identity: 15% PDB header:lyase/oxidoreductase Chain: G: PDB Molecule:4-hydroxy-2-oxovalerate aldolase; PDBTitle: crystal structure of a bifunctional aldolase-dehydrogenase :2 sequestering a reactive and volatile intermediate Phyre2 PDB 2cw6 chain B Region: 44 - 192 Aligned: 148 Modelled: 149 Confidence: 90.9% Identity: 9% PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria Phyre2 PDB 3ble chain A Region: 44 - 192 Aligned: 147 Modelled: 149 Confidence: 90.0% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:citramalate synthase from leptospira interrogans; PDBTitle: crystal structure of the catalytic domain of licms in2 complexed with malonate Phyre2 1 d1tv8a_ 2 c2yx0A_ 3 c3c8fA_ 4 c1r30A_ 5 d1r30a_ 6 c3t7vA_ 7 c2a5hC_ 8 c3cixA_ 9 c3rfaA_ 10 c2z2uA_ 11 d1olta_ 12 c3canA_ 13 c2qgqF_ 14 c3ivuB_ 15 c3eegB_ 16 c3ewbX_ 17 c2ftpA_ 18 c1nvmG_ 19 c2cw6B_ 20 c3bleA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1tv8a_ 100.0 32 Fold:TIM beta/alpha-barrel Superfamily:Radical SAM enzymes Family:MoCo biosynthesis proteins 2 c2yx0A_ 99.9 16 PDB header:metal binding protein Chain: A: PDB Molecule:radical sam enzyme; PDBTitle: crystal structure of p. horikoshii tyw1 3 c3c8fA_ 99.8 12 PDB header:oxidoreductase Chain: A: PDB Molecule:pyruvate formate-lyase 1-activating enzyme; PDBTitle: 4fe-4s-pyruvate formate-lyase activating enzyme with2 partially disordered adomet 4 c1r30A_ 99.8 17 PDB header:transferase Chain: A: PDB Molecule:biotin synthase; PDBTitle: the crystal structure of biotin synthase, an s-2 adenosylmethionine-dependent radical enzyme 5 d1r30a_ 99.8 17 Fold:TIM beta/alpha-barrel Superfamily:Radical SAM enzymes Family:Biotin synthase 6 c3t7vA_ 99.8 14 PDB header:transferase Chain: A: PDB Molecule:methylornithine synthase pylb; PDBTitle: crystal structure of methylornithine synthase (pylb) 7 c2a5hC_ 99.8 18 PDB header:isomerase Chain: C: PDB Molecule:l-lysine 2,3-aminomutase; PDBTitle: 2.1 angstrom x-ray crystal structure of lysine-2,3-aminomutase from2 clostridium subterminale sb4, with michaelis analog (l-alpha-lysine3 external aldimine form of pyridoxal-5'-phosphate). 8 c3cixA_ 99.7 14 PDB header:adomet binding protein Chain: A: PDB Molecule:fefe-hydrogenase maturase; PDBTitle: x-ray structure of the [fefe]-hydrogenase maturase hyde from2 thermotoga maritima in complex with thiocyanate 9 c3rfaA_ 99.7 17 PDB header:oxidoreductase Chain: A: PDB Molecule:ribosomal rna large subunit methyltransferase n; PDBTitle: x-ray structure of rlmn from escherichia coli in complex with s-2 adenosylmethionine 10 c2z2uA_ 99.5 15 PDB header:metal binding protein Chain: A: PDB Molecule:upf0026 protein mj0257; PDBTitle: crystal structure of archaeal tyw1 11 d1olta_ 99.5 13 Fold:TIM beta/alpha-barrel Superfamily:Radical SAM enzymes Family:Oxygen-independent coproporphyrinogen III oxidase HemN 12 c3canA_ 99.5 17 PDB header:lyase activator Chain: A: PDB Molecule:pyruvate-formate lyase-activating enzyme; PDBTitle: crystal structure of a domain of pyruvate-formate lyase-activating2 enzyme from bacteroides vulgatus atcc 8482 13 c2qgqF_ 99.1 9 PDB header:structural genomics, unknown function Chain: F: PDB Molecule:protein tm_1862; PDBTitle: crystal structure of tm_1862 from thermotoga maritima.2 northeast structural genomics consortium target vr77 14 c3ivuB_ 97.4 12 PDB header:transferase Chain: B: PDB Molecule:homocitrate synthase, mitochondrial; PDBTitle: homocitrate synthase lys4 bound to 2-og 15 c3eegB_ 95.6 14 PDB header:transferase Chain: B: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of a 2-isopropylmalate synthase from2 cytophaga hutchinsonii 16 c3ewbX_ 95.0 9 PDB header:transferase Chain: X: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of n-terminal domain of putative 2-2 isopropylmalate synthase from listeria monocytogenes 17 c2ftpA_ 92.7 13 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa 18 c1nvmG_ 91.6 15 PDB header:lyase/oxidoreductase Chain: G: PDB Molecule:4-hydroxy-2-oxovalerate aldolase; PDBTitle: crystal structure of a bifunctional aldolase-dehydrogenase :2 sequestering a reactive and volatile intermediate 19 c2cw6B_ 90.9 9 PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria 20 c3bleA_ 90.0 13 PDB header:transferase Chain: A: PDB Molecule:citramalate synthase from leptospira interrogans; PDBTitle: crystal structure of the catalytic domain of licms in2 complexed with malonate 21 d1nvma2 not modelled 89.8 14 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:HMGL-like 22 c1ydnA_ not modelled 89.5 10 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of the hmg-coa lyase from brucella melitensis,2 northeast structural genomics target lr35. 23 c1ydoC_ not modelled 87.8 12 PDB header:lyase Chain: C: PDB Molecule:hmg-coa lyase; PDBTitle: crystal structure of the bacillis subtilis hmg-coa lyase, northeast2 structural genomics target sr181. 24 c1sr9A_ not modelled 82.2 10 PDB header:transferase Chain: A: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of leua from mycobacterium tuberculosis 25 c2nx9B_ not modelled 82.1 12 PDB header:lyase Chain: B: PDB Molecule:oxaloacetate decarboxylase 2, subunit alpha; PDBTitle: crystal structure of the carboxyltransferase domain of the2 oxaloacetate decarboxylase na+ pump from vibrio cholerae 26 d1qt1a_ not modelled 81.1 14 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 27 c3khdC_ not modelled 79.4 11 PDB header:transferase Chain: C: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure of pff1300w. 28 c2wcsA_ not modelled 75.4 13 PDB header:hydrolase Chain: A: PDB Molecule:alpha amylase, catalytic region; PDBTitle: crystal structure of debranching enzyme from nostoc2 punctiforme (npde) 29 d1qhoa4 not modelled 74.1 15 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 30 c2zyfA_ not modelled 70.8 12 PDB header:transferase Chain: A: PDB Molecule:homocitrate synthase; PDBTitle: crystal structure of homocitrate synthase from thermus thermophilus2 complexed with magnesuim ion and alpha-ketoglutarate 31 d2aaaa2 not modelled 70.7 14 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 32 d1muwa_ not modelled 68.9 17 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 33 d3bmva4 not modelled 68.5 13 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 34 c1lwhA_ not modelled 67.6 17 PDB header:transferase Chain: A: PDB Molecule:4-alpha-glucanotransferase; PDBTitle: crystal structure of t. maritima 4-alpha-glucanotransferase 35 d1pama4 not modelled 66.7 10 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 36 c1m53A_ not modelled 66.5 13 PDB header:isomerase Chain: A: PDB Molecule:isomaltulose synthase; PDBTitle: crystal structure of isomaltulose synthase (pali) from2 klebsiella sp. lx3 37 c3hpxB_ not modelled 65.3 13 PDB header:transferase Chain: B: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of mycobacterium tuberculosis leua active site2 domain 1-425 (truncation mutant delta:426-644) 38 c3a47A_ not modelled 64.6 9 PDB header:hydrolase Chain: A: PDB Molecule:oligo-1,6-glucosidase; PDBTitle: crystal structure of isomaltase from saccharomyces cerevisiae 39 d1cgta4 not modelled 64.0 9 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 40 d1bf2a3 not modelled 64.0 18 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 41 d1h3ga3 not modelled 63.7 11 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 42 d1gjwa2 not modelled 63.0 14 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 43 d1uoka2 not modelled 61.5 19 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 44 d1cxla4 not modelled 58.4 9 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 45 c1ea9D_ not modelled 58.0 13 PDB header:hydrolase Chain: D: PDB Molecule:cyclomaltodextrinase; PDBTitle: cyclomaltodextrinase 46 d1m53a2 not modelled 57.5 16 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 47 c2aaaA_ not modelled 56.5 10 PDB header:glycosidase Chain: A: PDB Molecule:alpha-amylase; PDBTitle: calcium binding in alpha-amylases: an x-ray diffraction2 study at 2.1 angstroms resolution of two enzymes from3 aspergillus 48 d1gvia3 not modelled 56.1 10 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 49 c1uokA_ not modelled 55.7 16 PDB header:glucosidase Chain: A: PDB Molecule:oligo-1,6-glucosidase; PDBTitle: crystal structure of b. cereus oligo-1,6-glucosidase 50 d2guya2 not modelled 54.6 11 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 51 d1e43a2 not modelled 53.6 11 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 52 c1qhoA_ not modelled 52.3 17 PDB header:hydrolase Chain: A: PDB Molecule:alpha-amylase; PDBTitle: five-domain alpha-amylase from bacillus stearothermophilus,2 maltose/acarbose complex 53 d1g5aa2 not modelled 52.2 12 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 54 d1lwha2 not modelled 50.7 16 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 55 c2ze0A_ not modelled 50.0 16 PDB header:hydrolase Chain: A: PDB Molecule:alpha-glucosidase; PDBTitle: alpha-glucosidase gsj 56 c2zidA_ not modelled 49.7 16 PDB header:hydrolase Chain: A: PDB Molecule:dextran glucosidase; PDBTitle: crystal structure of dextran glucosidase e236q complex with2 isomaltotriose 57 c3edeB_ not modelled 49.7 14 PDB header:hydrolase Chain: B: PDB Molecule:cyclomaltodextrinase; PDBTitle: structural base for cyclodextrin hydrolysis 58 c1bf2A_ not modelled 48.9 10 PDB header:hydrolase Chain: A: PDB Molecule:isoamylase; PDBTitle: structure of pseudomonas isoamylase 59 c2ya0A_ not modelled 48.7 16 PDB header:hydrolase Chain: A: PDB Molecule:putative alkaline amylopullulanase; PDBTitle: catalytic module of the multi-modular glycogen-degrading2 pneumococcal virulence factor spua 60 d1ob0a2 not modelled 48.6 14 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 61 c3dxiB_ not modelled 48.6 9 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative aldolase; PDBTitle: crystal structure of the n-terminal domain of a putative2 aldolase (bvu_2661) from bacteroides vulgatus 62 c1gjuA_ not modelled 48.4 16 PDB header:transferase Chain: A: PDB Molecule:maltodextrin glycosyltransferase; PDBTitle: maltosyltransferase from thermotoga maritima 63 c2qpuB_ not modelled 47.9 17 PDB header:hydrolase Chain: B: PDB Molecule:alpha-amylase type a isozyme; PDBTitle: sugar tongs mutant s378p in complex with acarbose 64 d1ea9c3 not modelled 47.8 17 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 65 c1jibA_ not modelled 46.8 16 PDB header:hydrolase Chain: A: PDB Molecule:neopullulanase; PDBTitle: complex of alpha-amylase ii (tva ii) from thermoactinomyces2 vulgaris r-47 with maltotetraose based on a crystal soaked3 with maltohexaose. 66 c2z1kA_ not modelled 46.4 19 PDB header:hydrolase Chain: A: PDB Molecule:(neo)pullulanase; PDBTitle: crystal structure of ttha1563 from thermus thermophilus hb8 67 d1yhta1 not modelled 45.8 20 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-N-acetylhexosaminidase catalytic domain 68 c2zq0B_ not modelled 45.7 17 PDB header:hydrolase Chain: B: PDB Molecule:alpha-glucosidase (alpha-glucosidase susb); PDBTitle: crystal structure of susb complexed with acarbose 69 d2gjpa2 not modelled 44.5 13 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 70 c2jvfA_ not modelled 44.1 12 PDB header:de novo protein Chain: A: PDB Molecule:de novo protein m7; PDBTitle: solution structure of m7, a computationally-designed2 artificial protein 71 c3czkA_ not modelled 43.4 16 PDB header:hydrolase Chain: A: PDB Molecule:sucrose hydrolase; PDBTitle: crystal structure analysis of sucrose hydrolase(suh) e322q-2 sucrose complex 72 d1u7pa_ not modelled 42.9 8 Fold:HAD-like Superfamily:HAD-like Family:Magnesium-dependent phosphatase-1, Mdp1 73 c1zjaB_ not modelled 42.8 14 PDB header:isomerase Chain: B: PDB Molecule:trehalulose synthase; PDBTitle: crystal structure of the trehalulose synthase mutb from2 pseudomonas mesoacidophila mx-45 (triclinic form) 74 c1qysA_ not modelled 42.3 9 PDB header:de novo protein Chain: A: PDB Molecule:top7; PDBTitle: crystal structure of top7: a computationally designed2 protein with a novel fold 75 d1ua7a2 not modelled 42.1 9 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 76 c3dhuC_ not modelled 41.9 16 PDB header:hydrolase Chain: C: PDB Molecule:alpha-amylase; PDBTitle: crystal structure of an alpha-amylase from lactobacillus2 plantarum 77 c1ehaA_ not modelled 41.5 10 PDB header:hydrolase Chain: A: PDB Molecule:glycosyltrehalose trehalohydrolase; PDBTitle: crystal structure of glycosyltrehalose trehalohydrolase2 from sulfolobus solfataricus 78 c1gviA_ not modelled 40.9 15 PDB header:hydrolase Chain: A: PDB Molecule:maltogenic amylase; PDBTitle: thermus maltogenic amylase in complex with beta-cd 79 d1j0ha3 not modelled 40.8 15 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 80 c2taaA_ not modelled 39.2 11 PDB header:hydrolase (o-glycosyl) Chain: A: PDB Molecule:taka-amylase a; PDBTitle: structure and possible catalytic residues of taka-amylase a 81 d1cyga4 not modelled 39.2 8 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 82 c2dh3A_ not modelled 38.1 11 PDB header:transport protein, signaling protein Chain: A: PDB Molecule:4f2 cell-surface antigen heavy chain; PDBTitle: crystal structure of human ed-4f2hc 83 c3k8kB_ not modelled 38.1 19 PDB header:membrane protein Chain: B: PDB Molecule:alpha-amylase, susg; PDBTitle: crystal structure of susg 84 d1ud2a2 not modelled 37.4 16 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 85 c1bagA_ not modelled 36.7 17 PDB header:alpha-amylase Chain: A: PDB Molecule:alpha-1,4-glucan-4-glucanohydrolase; PDBTitle: alpha-amylase from bacillus subtilis complexed with2 maltopentaose 86 c1jgiA_ not modelled 36.0 12 PDB header:transferase Chain: A: PDB Molecule:amylosucrase; PDBTitle: crystal structure of the active site mutant glu328gln of2 amylosucrase from neisseria polysaccharea in complex with3 the natural substrate sucrose 87 c1cygA_ not modelled 35.9 10 PDB header:glycosyltransferase Chain: A: PDB Molecule:cyclodextrin glucanotransferase; PDBTitle: cyclodextrin glucanotransferase (e.c.2.4.1.19) (cgtase) 88 c3gh7A_ not modelled 35.7 25 PDB header:hydrolase Chain: A: PDB Molecule:beta-hexosaminidase; PDBTitle: crystal structure of beta-hexosaminidase from paenibacillus2 sp. ts12 in complex with galnac 89 d1jaka1 not modelled 34.8 30 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-N-acetylhexosaminidase catalytic domain 90 d1mzha_ not modelled 34.6 11 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 91 d1z6ma1 not modelled 33.8 18 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:DsbA-like 92 c2yl8A_ not modelled 33.7 18 PDB header:hydrolase Chain: A: PDB Molecule:beta-n-acetylhexosaminidase; PDBTitle: inhibition of the pneumococcal virulence factor strh and2 molecular insights into n-glycan recognition and3 hydrolysis 93 d1ht6a2 not modelled 33.7 17 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 94 c3os4A_ not modelled 32.8 12 PDB header:transferase Chain: A: PDB Molecule:nicotinate phosphoribosyltransferase; PDBTitle: the crystal structure of nicotinate phosphoribosyltransferase from2 yersinia pestis 95 c3na8A_ not modelled 32.1 17 PDB header:lyase Chain: A: PDB Molecule:putative dihydrodipicolinate synthetase; PDBTitle: crystal structure of a putative dihydrodipicolinate synthetase from2 pseudomonas aeruginosa 96 c2rfgB_ not modelled 31.8 18 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from hahella2 chejuensis at 1.5a resolution 97 d1pkla2 not modelled 31.7 9 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 98 c3bmwA_ not modelled 31.5 13 PDB header:transferase Chain: A: PDB Molecule:cyclomaltodextrin glucanotransferase; PDBTitle: cyclodextrin glycosyl transferase from thermoanerobacterium2 thermosulfurigenes em1 mutant s77p complexed with a maltoheptaose3 inhibitor 99 c3zt5D_ not modelled 31.4 18 PDB header:hydrolase Chain: D: PDB Molecule:putative glucanohydrolase pep1a; PDBTitle: glge isoform 1 from streptomyces coelicolor with maltose2 bound 100 d1yx1a1 not modelled 30.2 17 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:KguE-like 101 c3ngjC_ not modelled 30.0 10 PDB header:lyase Chain: C: PDB Molecule:deoxyribose-phosphate aldolase; PDBTitle: crystal structure of a putative deoxyribose-phosphate aldolase from2 entamoeba histolytica 102 c2ya1A_ not modelled 29.7 14 PDB header:hydrolase Chain: A: PDB Molecule:putative alkaline amylopullulanase; PDBTitle: product complex of a multi-modular glycogen-degrading2 pneumococcal virulence factor spua 103 d1o0ya_ not modelled 29.5 9 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 104 d1mxga2 not modelled 28.5 15 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 105 d1avaa2 not modelled 27.7 17 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 106 c1bplA_ not modelled 27.3 13 PDB header:glycosyltransferase Chain: A: PDB Molecule:alpha-1,4-glucan-4-glucanohydrolase; PDBTitle: glycosyltransferase 107 d1wzla3 not modelled 27.3 16 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 108 c3faxA_ not modelled 27.0 14 PDB header:hydrolase Chain: A: PDB Molecule:reticulocyte binding protein; PDBTitle: the crystal structure of gbs pullulanase sap in complex with2 maltotetraose 109 d1yira1 not modelled 26.7 14 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:Monomeric nicotinate phosphoribosyltransferase C-terminal domain 110 c2kl5A_ not modelled 25.9 55 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein yutd; PDBTitle: solution nmr structure of protein yutd from b.subtilis, northeast2 structural genomics consortium target sr232 111 d1d3ga_ not modelled 25.5 24 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 112 d1nowa1 not modelled 25.0 18 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-N-acetylhexosaminidase catalytic domain 113 d1mioa_ not modelled 24.8 8 Fold:Chelatase-like Superfamily:"Helical backbone" metal receptor Family:Nitrogenase iron-molybdenum protein 114 c3n2xB_ not modelled 24.7 19 PDB header:lyase Chain: B: PDB Molecule:uncharacterized protein yage; PDBTitle: crystal structure of yage, a prophage protein belonging to the2 dihydrodipicolinic acid synthase family from e. coli k12 in complex3 with pyruvate 115 c2epoB_ not modelled 24.6 11 PDB header:hydrolase Chain: B: PDB Molecule:n-acetyl-beta-d-glucosaminidase; PDBTitle: n-acetyl-b-d-glucosaminidase (gcna) from streptococcus gordonii 116 c1e40A_ not modelled 24.3 11 PDB header:hydrolase Chain: A: PDB Molecule:alpha-amylase; PDBTitle: tris/maltotriose complex of chimaeric amylase from b.2 amyloliquefaciens and b. licheniformis at 2.2a 117 d1pbya1 not modelled 23.6 13 Fold:Cytochrome c Superfamily:Cytochrome c Family:Quinohemoprotein amine dehydrogenase A chain, domains 1 and 2 118 d2bhua3 not modelled 23.5 10 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 119 c1tcmB_ not modelled 23.4 10 PDB header:glycosyltransferase Chain: B: PDB Molecule:cyclodextrin glycosyltransferase; PDBTitle: cyclodextrin glycosyltransferase w616a mutant from bacillus2 circulans strain 251 120 c1ud8A_ not modelled 22.8 13 PDB header:hydrolase Chain: A: PDB Molecule:amylase; PDBTitle: crystal structure of amyk38 with lithium ion

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0