PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3eegB_

Fold library id	PDB Header	Molecule	Title
c3eegB_	PDB header: transferase	Chain: B: PDB Molecule: 2-isopropylmalate synthase;	PDBTitle: crystal structure of a 2-isopropylmalate synthase from2 cytophaga hutchinsonii

Links to external resources
Added to library: Tue Mar 16 13:15:43 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence G K R I F V F D T T L R D G E Q L N T E E K I I V A K A L D E L G V D V I E A G F P V S S P G D F N S V V E I T K A V T R P T I C A L T R A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T T T
S
T T T
T T
S S
S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence K E A D I N I A G E A L R F A K R S R I H T G I G S S D I H I E H K L R S T R E N I L E X A V A A V K Q A K K V V H E V E F F C E D A G R A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
S S
S T S T T
T T T T
S S S T T T S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence D Q A F L A R X V E A V I E A G A D V V N I P D T T G Y X L P W Q Y G E R I K Y L X D N V S N I D K A I L S A H C H N D L G L A T A N S L A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T
S
S S S
T T G G G S
B
S S S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . .

Sequence A L Q N G A R Q V E C T I N G I G E R A G N T A L E E V V X A X E C H K E T L G L E T G I N H K K L V P I S H L V S T L X R X

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T
B G G G
S T T
B
B T T
S
G G G T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	G	K	R	I	F	V	F	D	T	T	L	R	D	G	E	Q	L	N	T	E	E	K	I	I	V	A	K	A	L	D	E	L	G	V	D	V	I	E	A	G	F	P	V	S	S	P	G	D	F	N	S	V	V	E	I	T	K	A	V	T	R	P	T	I	C	A	L	T	R	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														S																	T	T	T		S							T	T	T													T	T			S	S								S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	K	E	A	D	I	N	I	A	G	E	A	L	R	F	A	K	R	S	R	I	H	T	G	I	G	S	S	D	I	H	I	E	H	K	L	R	S	T	R	E	N	I	L	E	X	A	V	A	A	V	K	Q	A	K	K	V	V	H	E	V	E	F	F	C	E	D	A	G	R	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)													T	T		S	S										S							T	S	T	T			T	T	T	T														S	S								S	T	T	T	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	D	Q	A	F	L	A	R	X	V	E	A	V	I	E	A	G	A	D	V	V	N	I	P	D	T	T	G	Y	X	L	P	W	Q	Y	G	E	R	I	K	Y	L	X	D	N	V	S	N	I	D	K	A	I	L	S	A	H	C	H	N	D	L	G	L	A	T	A	N	S	L	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														T	T	T		S							S	S	S																			T	T	G	G	G	S							B		S	S	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.
Sequence	A	L	Q	N	G	A	R	Q	V	E	C	T	I	N	G	I	G	E	R	A	G	N	T	A	L	E	E	V	V	X	A	X	E	C	H	K	E	T	L	G	L	E	T	G	I	N	H	K	K	L	V	P	I	S	H	L	V	S	T	L	X	R	X
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T	T							B	G	G	G			S	T	T		B		B										T	T									S			G	G	G												T	T