PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3ewbX_

Fold library id	PDB Header	Molecule	Title
c3ewbX_	PDB header: transferase	Chain: X: PDB Molecule: 2-isopropylmalate synthase;	PDBTitle: crystal structure of n-terminal domain of putative 2-2 isopropylmalate synthase from listeria monocytogenes

Links to external resources
Added to library: Tue Mar 16 12:25:33 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence S L K K I Q F F D T T L R D G E N F D V K E K I Q I A L Q L E K L G I D V I E A G F P I S S P G D F E C V K A I A K A I K H C S V T G L A R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T
T
S
G G G
S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence C V E G D I D R A E E A L K D A V S P Q I H I F L A T S D V H X E Y K L K X S R A E V L A S I K H H I S Y A R Q K F D V V Q F S P E D A T R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S T T
S S
S T T
T T
S
T G G G

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence S D R A F L I E A V Q T A I D A G A T V I N I P D T V G Y T N P T E F G Q L F Q D L R R E I K Q F D D I I F A S H C H D D L G X A T A N A L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T
S S S
T T G G G S
B
T T S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 .

Sequence A A I E N G A R R V E G T I N G I G E R A G N T A L E E V A V A L H I R K D F Y Q A E T N I V L N Q F K N S S D L I S R L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
B G G G
T T T
B
B T
G G G

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	S	L	K	K	I	Q	F	F	D	T	T	L	R	D	G	E	N	F	D	V	K	E	K	I	Q	I	A	L	Q	L	E	K	L	G	I	D	V	I	E	A	G	F	P	I	S	S	P	G	D	F	E	C	V	K	A	I	A	K	A	I	K	H	C	S	V	T	G	L	A	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											T	T	T																					T		S							G	G	G																	S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	C	V	E	G	D	I	D	R	A	E	E	A	L	K	D	A	V	S	P	Q	I	H	I	F	L	A	T	S	D	V	H	X	E	Y	K	L	K	X	S	R	A	E	V	L	A	S	I	K	H	H	I	S	Y	A	R	Q	K	F	D	V	V	Q	F	S	P	E	D	A	T	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S												T	T		S	S										S							T	T																				T	T		S								T	G	G	G
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	S	D	R	A	F	L	I	E	A	V	Q	T	A	I	D	A	G	A	T	V	I	N	I	P	D	T	V	G	Y	T	N	P	T	E	F	G	Q	L	F	Q	D	L	R	R	E	I	K	Q	F	D	D	I	I	F	A	S	H	C	H	D	D	L	G	X	A	T	A	N	A	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S															T	T									S	S	S																			T	T	G	G	G	S							B		T	T	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.
Sequence	A	A	I	E	N	G	A	R	R	V	E	G	T	I	N	G	I	G	E	R	A	G	N	T	A	L	E	E	V	A	V	A	L	H	I	R	K	D	F	Y	Q	A	E	T	N	I	V	L	N	Q	F	K	N	S	S	D	L	I	S	R	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					T	T							B	G	G	G			T	T	T		B		B											T												G	G	G