Phyre 2 Results for P30958

Email	l.a.kelley@imperial.ac.uk
Description	P30958
Date	Thu Jan 5 11:46:49 GMT 2012
Unique Job ID	3199380b60840b21

Summary

Top model

Image coloured by rainbow N → C terminus

Model (left) based on template c2eyqA_

Top template information

PDB header:hydrolase
Chain: A: PDB Molecule:transcription-repair coupling factor;
PDBTitle: crystal structure of escherichia coli transcription-repair2 coupling factor

Confidence and coverage

Confidence:

100.0%

Coverage:

100%

1146 residues (100% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M P E Q Y R Y T L P V K A G E Q R L L G E L T G A A C A T L V A E I A E R H A G P V V L I A P D M Q N A L R L H D E I S

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence Q F T D Q M V M N L A D W E T L P Y D S F S P H Q D I I S S R L S T L Y Q L P T M Q R G V L I V P V N T L M Q R V C P H

Secondary structure

SS confidence

Disorder
? ? ?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence S F L H G H A L V M K K G Q R L S R D A L R T Q L D S A G Y R H V D Q V M E H G E Y A T R G A L L D L F P M G S E L P Y

Secondary structure

SS confidence

Disorder
?

Disorder confidence

. . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240

Sequence R L D F F D D E I D S L R V F D V D S Q R T L E E V E A I N L L P A H E F P T D K A A I E L F R S Q W R D T F E V K R D

Secondary structure

SS confidence

Disorder
?

Disorder confidence

. . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280 . . . . . . . . . 290 . . . . . . . . . 300

Sequence P E H I Y Q Q V S K G T L P A G I E Y W Q P L F F S E P L P P L F S Y F P A N T L L V N T G D L E T S A E R F Q A D T L

Secondary structure

SS confidence

Disorder
?

Disorder confidence

. . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350 . . . . . . . . . 360

Sequence A R F E N R G V D P M R P L L P P Q S L W L R V D E L F S E L K N W P R V Q L K T E H L P T K A A N A N L G F Q K L P D

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ?
?
?
? ? ? ? ? ? ? ? ? ?
?
? ? ?

Disorder confidence

. . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence L A V Q A Q Q K A P L D A L R K F L E T F D G P V V F S V E S E G R R E A L G E L L A R I K I A P Q R I M R L D E A S D

Secondary structure

SS confidence

Disorder ? ? ? ? ? ?
? ? ? ? ?

Disorder confidence

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480

Sequence R G R Y L M I G A A E H G F V D T V R N L A L I C E S D L L G E R V A R R R Q D S R R T I N P D T L I R N L A E L H I G

Secondary structure

SS confidence

Disorder
? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 490 . . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540

Sequence Q P V V H L E H G V G R Y A G M T T L E A G G I T G E Y L M L T Y A N D A K L Y V P V S S L H L I S R Y A G G A E E N A

Secondary structure

SS confidence

Disorder
? ?
? ?
? ?
? ? ?

Disorder confidence

. . . . . . . . . 550 . . . . . . . . . 560 . . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600

Sequence P L H K L G G D A W S R A R Q K A A E K V R D V A A E L L D I Y A Q R A A K E G F A F K H D R E Q Y Q L F C D S F P F E

Secondary structure

SS confidence

Disorder ?
? ?
?
? ? ?
?

Disorder confidence

. . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630 . . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660

Sequence T T P D Q A Q A I N A V L S D M C Q P L A M D R L V C G D V G F G K T E V A M R A A F L A V D N H K Q V A V L V P T T L

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700 . . . . . . . . . 710 . . . . . . . . . 720

Sequence L A Q Q H Y D N F R D R F A N W P V R I E M I S R F R S A K E Q T Q I L A E V A E G K I D I L I G T H K L L Q S D V K F

Secondary structure

SS confidence

Disorder
?
? ?

Disorder confidence

. . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770 . . . . . . . . . 780

Sequence K D L G L L I V D E E H R F G V R H K E R I K A M R A N V D I L T L T A T P I P R T L N M A M S G M R D L S I I A T P P

Secondary structure

SS confidence

Disorder
?
?
? ? ? ? ? ? ?
? ?
? ?

Disorder confidence

. . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence A R R L A V K T F V R E Y D S M V V R E A I L R E I L R G G Q V Y Y L Y N D V E N I Q K A A E R L A E L V P E A R I A I

Secondary structure

SS confidence

Disorder ?

Disorder confidence

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900

Sequence G H G Q M R E R E L E R V M N D F H H Q R F N V L V C T T I I E T G I D I P T A N T I I I E R A D H F G L A Q L H Q L R

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 910 . . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960

Sequence G R V G R S H H Q A Y A W L L T P H P K A M T T D A Q K R L E A I A S L E D L G A G F A L A T H D L E I R G A G E L L G

Secondary structure

SS confidence

Disorder
? ? ? ? ?
? ?
?
?

Disorder confidence

. . . . . . . . . 970 . . . . . . . . . 980 . . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020

Sequence E E Q S G S M E T I G F S L Y M E L L E N A V D A L K A G R E P S L E D L T S Q Q T E V E L R M P S L L P D D F I P D V

Secondary structure

SS confidence

Disorder ?
? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 1030 . . . . . . . . . 1040 . . . . . . . . . 1050 . . . . . . . . . 1060 . . . . . . . . . 1070 . . . . . . . . . 1080

Sequence N T R L S F Y K R I A S A K T E N E L E E I K V E L I D R F G L L P D P A R T L L D I A R L R Q Q A Q K L G I R K L E G

Secondary structure

SS confidence

Disorder
? ?

Disorder confidence

. . . . . . . . . 1090 . . . . . . . . . 1100 . . . . . . . . . 1110 . . . . . . . . . 1120 . . . . . . . . . 1130 . . . . . . . . . 1140

Sequence N E K G G V I E F A E K N H V N P A W L I G L L Q K Q P Q H Y R L D G P T R L K F I Q D L S E R K T R I E W V R Q F M R

Secondary structure

SS confidence

Disorder ? ?
? ? ? ? ?
? ? ? ?

Disorder confidence

. . . . . . . .

Sequence E L E E N A I A

Secondary structure

SS confidence

Disorder
? ? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered

Alpha helix

Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 2eyq chain A

Region: 2 - 1147
Aligned: 1146
Modelled: 1146
Confidence: 100.0%
Identity: 100%
PDB header:hydrolase
Chain: A: PDB Molecule:transcription-repair coupling factor;
PDBTitle: crystal structure of escherichia coli transcription-repair2 coupling factor

Phyre2

PDB 3hjh chain A

Region: 5 - 450
Aligned: 446
Modelled: 446
Confidence: 100.0%
Identity: 100%
PDB header:hydrolase
Chain: A: PDB Molecule:transcription-repair-coupling factor;
PDBTitle: a rigid n-terminal clamp restrains the motor domains of the bacterial2 transcription-repair coupling factor

Phyre2

PDB 1gm5 chain A

Region: 548 - 965
Aligned: 401
Modelled: 418
Confidence: 100.0%
Identity: 37%
PDB header:helicase
Chain: A: PDB Molecule:recg;
PDBTitle: structure of recg bound to three-way dna junction

Phyre2

PDB 2eyq chain A domain 4

Region: 2 - 348
Aligned: 347
Modelled: 347
Confidence: 100.0%
Identity: 100%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: Tandem AAA-ATPase domain

Phyre2

PDB 2b2n chain A domain 1

Region: 26 - 333
Aligned: 308
Modelled: 308
Confidence: 100.0%
Identity: 100%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: Tandem AAA-ATPase domain

Phyre2

PDB 1t5l chain A domain 1

Region: 3 - 359
Aligned: 356
Modelled: 357
Confidence: 100.0%
Identity: 19%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: Tandem AAA-ATPase domain

Phyre2

PDB 2eyq chain A domain 5

Region: 779 - 989
Aligned: 211
Modelled: 211
Confidence: 100.0%
Identity: 100%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: Tandem AAA-ATPase domain

Phyre2

PDB 2eyq chain A domain 3

Region: 546 - 778
Aligned: 233
Modelled: 233
Confidence: 100.0%
Identity: 100%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: Tandem AAA-ATPase domain

Phyre2

PDB 2v1x chain B

Region: 579 - 1047
Aligned: 443
Modelled: 469
Confidence: 100.0%
Identity: 16%
PDB header:hydrolase
Chain: B: PDB Molecule:atp-dependent dna helicase q1;
PDBTitle: crystal structure of human recq-like dna helicase

Phyre2

PDB 2xgj chain A

Region: 597 - 927
Aligned: 309
Modelled: 331
Confidence: 100.0%
Identity: 22%
PDB header:hydrolase/rna
Chain: A: PDB Molecule:atp-dependent rna helicase dob1;
PDBTitle: structure of mtr4, a dexh helicase involved in nuclear rna2 processing and surveillance

Phyre2

PDB 4a4z chain A

Region: 597 - 931
Aligned: 313
Modelled: 335
Confidence: 100.0%
Identity: 23%
PDB header:hydrolase
Chain: A: PDB Molecule:antiviral helicase ski2;
PDBTitle: crystal structure of the s. cerevisiae dexh helicase ski2 bound to2 amppnp

Phyre2

PDB 1oyw chain A

Region: 586 - 951
Aligned: 343
Modelled: 366
Confidence: 100.0%
Identity: 21%
PDB header:hydrolase
Chain: A: PDB Molecule:atp-dependent dna helicase;
PDBTitle: structure of the recq catalytic core

Phyre2

PDB 3bxz chain A

Region: 547 - 922
Aligned: 358
Modelled: 376
Confidence: 100.0%
Identity: 19%
PDB header:transport protein
Chain: A: PDB Molecule:preprotein translocase subunit seca;
PDBTitle: crystal structure of the isolated dead motor domains from2 escherichia coli seca

Phyre2

PDB 3l9o chain A

Region: 597 - 945
Aligned: 320
Modelled: 345
Confidence: 100.0%
Identity: 21%
PDB header:hydrolase
Chain: A: PDB Molecule:atp-dependent rna helicase dob1;
PDBTitle: crystal structure of mtr4, a co-factor of the nuclear exosome

Phyre2

PDB 1gm5 chain A domain 3

Region: 549 - 781
Aligned: 228
Modelled: 233
Confidence: 100.0%
Identity: 35%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: Tandem AAA-ATPase domain

Phyre2

PDB 1gl9 chain B

Region: 587 - 928
Aligned: 322
Modelled: 342
Confidence: 100.0%
Identity: 17%
PDB header:topoisomerase
Chain: B: PDB Molecule:reverse gyrase;
PDBTitle: archaeoglobus fulgidus reverse gyrase complexed with adpnp

Phyre2

PDB 2vbc chain A

Region: 622 - 986
Aligned: 321
Modelled: 336
Confidence: 100.0%
Identity: 18%
PDB header:hydrolase
Chain: A: PDB Molecule:dengue 4 ns3 full-length protein;
PDBTitle: crystal structure of the ns3 protease-helicase from dengue2 virus

Phyre2

PDB 2va8 chain A

Region: 586 - 930
Aligned: 328
Modelled: 345
Confidence: 100.0%
Identity: 17%
PDB header:hydrolase
Chain: A: PDB Molecule:ski2-type helicase;
PDBTitle: dna repair helicase hel308

Phyre2

PDB 3rc8 chain A

Region: 587 - 917
Aligned: 298
Modelled: 318
Confidence: 100.0%
Identity: 15%
PDB header:hydrolase/rna
Chain: A: PDB Molecule:atp-dependent rna helicase supv3l1, mitochondrial;
PDBTitle: human mitochondrial helicase suv3 in complex with short rna fragment

Phyre2

PDB 2fsg chain A

Region: 552 - 1072
Aligned: 460
Modelled: 492
Confidence: 100.0%
Identity: 20%
PDB header:protein transport
Chain: A: PDB Molecule:preprotein translocase seca subunit;
PDBTitle: complex seca:atp from escherichia coli

Phyre2

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Detailed template information

#	Template	Alignment Coverage	3D Model	Confidence	% i.d.	Template Information

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server

Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]

If you use the binding site predictions from 3DLigandSite, please also cite:

3DLigandSite: predicting ligand-binding sites using similar structures.

Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]

Imperial College London

Lawrence Kelley, Benjamin Jefferys

Disclaimer

Terms and Conditions

Component software

Template detection: HHpred 1.51

Secondary structure prediction: Psi-pred 2.5

Disorder prediction: Disopred 2.4

Transmembrane prediction: Memsat_SVM

Multi-template modelling and ab initio: Poing 1.0

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence	M	P	E	Q	Y	R	Y	T	L	P	V	K	A	G	E	Q	R	L	L	G	E	L	T	G	A	A	C	A	T	L	V	A	E	I	A	E	R	H	A	G	P	V	V	L	I	A	P	D	M	Q	N	A	L	R	L	H	D	E	I	S
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence	Q	F	T	D	Q	M	V	M	N	L	A	D	W	E	T	L	P	Y	D	S	F	S	P	H	Q	D	I	I	S	S	R	L	S	T	L	Y	Q	L	P	T	M	Q	R	G	V	L	I	V	P	V	N	T	L	M	Q	R	V	C	P	H
Secondary structure
SS confidence
Disorder																						?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence	S	F	L	H	G	H	A	L	V	M	K	K	G	Q	R	L	S	R	D	A	L	R	T	Q	L	D	S	A	G	Y	R	H	V	D	Q	V	M	E	H	G	E	Y	A	T	R	G	A	L	L	D	L	F	P	M	G	S	E	L	P	Y
Secondary structure
SS confidence
Disorder																																				?
Disorder confidence

	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence	R	L	D	F	F	D	D	E	I	D	S	L	R	V	F	D	V	D	S	Q	R	T	L	E	E	V	E	A	I	N	L	L	P	A	H	E	F	P	T	D	K	A	A	I	E	L	F	R	S	Q	W	R	D	T	F	E	V	K	R	D
Secondary structure
SS confidence
Disorder																				?
Disorder confidence

	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence	P	E	H	I	Y	Q	Q	V	S	K	G	T	L	P	A	G	I	E	Y	W	Q	P	L	F	F	S	E	P	L	P	P	L	F	S	Y	F	P	A	N	T	L	L	V	N	T	G	D	L	E	T	S	A	E	R	F	Q	A	D	T	L
Secondary structure
SS confidence
Disorder											?
Disorder confidence

	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence	A	R	F	E	N	R	G	V	D	P	M	R	P	L	L	P	P	Q	S	L	W	L	R	V	D	E	L	F	S	E	L	K	N	W	P	R	V	Q	L	K	T	E	H	L	P	T	K	A	A	N	A	N	L	G	F	Q	K	L	P	D
Secondary structure
SS confidence
Disorder						?	?	?	?	?	?	?	?	?		?				?																						?	?	?	?	?	?	?	?	?	?			?				?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	L	A	V	Q	A	Q	Q	K	A	P	L	D	A	L	R	K	F	L	E	T	F	D	G	P	V	V	F	S	V	E	S	E	G	R	R	E	A	L	G	E	L	L	A	R	I	K	I	A	P	Q	R	I	M	R	L	D	E	A	S	D
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?																																																?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence	R	G	R	Y	L	M	I	G	A	A	E	H	G	F	V	D	T	V	R	N	L	A	L	I	C	E	S	D	L	L	G	E	R	V	A	R	R	R	Q	D	S	R	R	T	I	N	P	D	T	L	I	R	N	L	A	E	L	H	I	G
Secondary structure
SS confidence
Disorder																														?	?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence	Q	P	V	V	H	L	E	H	G	V	G	R	Y	A	G	M	T	T	L	E	A	G	G	I	T	G	E	Y	L	M	L	T	Y	A	N	D	A	K	L	Y	V	P	V	S	S	L	H	L	I	S	R	Y	A	G	G	A	E	E	N	A
Secondary structure
SS confidence
Disorder																				?	?			?	?																				?	?										?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence	P	L	H	K	L	G	G	D	A	W	S	R	A	R	Q	K	A	A	E	K	V	R	D	V	A	A	E	L	L	D	I	Y	A	Q	R	A	A	K	E	G	F	A	F	K	H	D	R	E	Q	Y	Q	L	F	C	D	S	F	P	F	E
Secondary structure
SS confidence
Disorder	?			?	?		?																														?	?	?																					?
Disorder confidence

	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660
Sequence	T	T	P	D	Q	A	Q	A	I	N	A	V	L	S	D	M	C	Q	P	L	A	M	D	R	L	V	C	G	D	V	G	F	G	K	T	E	V	A	M	R	A	A	F	L	A	V	D	N	H	K	Q	V	A	V	L	V	P	T	T	L
Secondary structure
SS confidence
Disorder																?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720
Sequence	L	A	Q	Q	H	Y	D	N	F	R	D	R	F	A	N	W	P	V	R	I	E	M	I	S	R	F	R	S	A	K	E	Q	T	Q	I	L	A	E	V	A	E	G	K	I	D	I	L	I	G	T	H	K	L	L	Q	S	D	V	K	F
Secondary structure
SS confidence
Disorder																									?		?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780
Sequence	K	D	L	G	L	L	I	V	D	E	E	H	R	F	G	V	R	H	K	E	R	I	K	A	M	R	A	N	V	D	I	L	T	L	T	A	T	P	I	P	R	T	L	N	M	A	M	S	G	M	R	D	L	S	I	I	A	T	P	P
Secondary structure
SS confidence
Disorder																?																											?			?	?	?	?	?	?	?				?	?		?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	A	R	R	L	A	V	K	T	F	V	R	E	Y	D	S	M	V	V	R	E	A	I	L	R	E	I	L	R	G	G	Q	V	Y	Y	L	Y	N	D	V	E	N	I	Q	K	A	A	E	R	L	A	E	L	V	P	E	A	R	I	A	I
Secondary structure
SS confidence
Disorder	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900
Sequence	G	H	G	Q	M	R	E	R	E	L	E	R	V	M	N	D	F	H	H	Q	R	F	N	V	L	V	C	T	T	I	I	E	T	G	I	D	I	P	T	A	N	T	I	I	I	E	R	A	D	H	F	G	L	A	Q	L	H	Q	L	R
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960
Sequence	G	R	V	G	R	S	H	H	Q	A	Y	A	W	L	L	T	P	H	P	K	A	M	T	T	D	A	Q	K	R	L	E	A	I	A	S	L	E	D	L	G	A	G	F	A	L	A	T	H	D	L	E	I	R	G	A	G	E	L	L	G
Secondary structure
SS confidence
Disorder																			?	?	?	?	?																		?	?										?						?
Disorder confidence

	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020
Sequence	E	E	Q	S	G	S	M	E	T	I	G	F	S	L	Y	M	E	L	L	E	N	A	V	D	A	L	K	A	G	R	E	P	S	L	E	D	L	T	S	Q	Q	T	E	V	E	L	R	M	P	S	L	L	P	D	D	F	I	P	D	V
Secondary structure
SS confidence
Disorder	?																											?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080
Sequence	N	T	R	L	S	F	Y	K	R	I	A	S	A	K	T	E	N	E	L	E	E	I	K	V	E	L	I	D	R	F	G	L	L	P	D	P	A	R	T	L	L	D	I	A	R	L	R	Q	Q	A	Q	K	L	G	I	R	K	L	E	G
Secondary structure
SS confidence
Disorder														?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140
Sequence	N	E	K	G	G	V	I	E	F	A	E	K	N	H	V	N	P	A	W	L	I	G	L	L	Q	K	Q	P	Q	H	Y	R	L	D	G	P	T	R	L	K	F	I	Q	D	L	S	E	R	K	T	R	I	E	W	V	R	Q	F	M	R
Secondary structure
SS confidence
Disorder	?	?										?	?	?	?	?																												?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.
Sequence	E	L	E	E	N	A	I	A
Secondary structure
SS confidence
Disorder					?	?	?	?
Disorder confidence