Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	K	A	P	K	R	A	F	V	C	N	E	C	G	A	D	Y	P	R	W	Q	G	Q	C	S	A	C	H	A	W	N	T	I	T	E	V	R	L	A	A	S	P	M	V	A	R	N	E	R	L	S	G	Y	A	G	S	A	G	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																								?								?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	K	V	Q	K	L	S	D	I	S	L	E	E	L	P	R	F	S	T	G	F	K	E	F	D	R	V	L	G	G	G	V	V	P	G	S	A	I	L	I	G	G	N	P	G	A	G	K	S	T	L	L	L	Q	T	L	C	K	L	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		Q	Q	M	K	T	L	Y	V	T	G	E	E	S	L	Q	Q	V	A	M	R	A	H	R	L	G	L	P	T	D	N	L	N	M	L	S	E	T	S	I	E	Q	I	C	L	I	A	E	E	E	Q	P	K	L	M	V	I	D	S	I	Q
Secondary structure
SS confidence
Disorder																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		V	M	H	M	A	D	V	Q	S	S	P	G	S	V	A	Q	V	R	E	T	A	A	Y	L	T	R	F	A	K	T	R	G	V	A	I	V	M	V	G	H	V	T	K	D	G	S	L	A	G	P	K	V	L	E	H	C	I	D	C	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?																														?		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		V	L	L	D	G	D	A	D	S	R	F	R	T	L	R	S	H	K	N	R	F	G	A	V	N	E	L	G	V	F	A	M	T	E	Q	G	L	R	E	V	S	N	P	S	A	I	F	L	S	R	G	D	E	V	T	S	G	S	S	V
Secondary structure
SS confidence
Disorder									?	?															?	?																									?	?	?	?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		M	V	V	W	E	G	T	R	P	L	L	V	E	I	Q	A	L	V	D	H	S	M	M	A	N	P	R	R	V	A	V	G	L	E	Q	N	R	L	A	I	L	L	A	V	L	H	R	H	G	G	L	Q	M	A	D	Q	D	V	F	V
Secondary structure
SS confidence
Disorder																	?	?	?	?	?	?	?	?	?	?	?	?	?	?			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		N	V	V	G	G	V	K	V	T	E	T	S	A	D	L	A	L	L	L	A	M	V	S	S	L	R	D	R	P	L	P	Q	D	L	V	V	F	G	E	V	G	L	A	G	E	I	R	P	V	P	S	G	Q	E	R	I	S	E	A	A
Secondary structure
SS confidence
Disorder									?																																									?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460
Sequence		K	H	G	F	R	R	A	I	V	P	A	A	N	V	P	K	K	A	P	E	G	M	Q	I	F	G	V	K	K	L	S	D	A	L	S	V	F	D	D	L
Secondary structure
SS confidence
Disorder																?	?	?	?																					?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3m6a chain C Region: 91 - 457 Aligned: 349 Modelled: 363 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: C: PDB Molecule:atp-dependent protease la 1; PDBTitle: crystal structure of bacillus subtilis lon c-terminal domain Phyre2 PDB 3k1j chain A Region: 98 - 459 Aligned: 362 Modelled: 362 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:atp-dependent protease lon; PDBTitle: crystal structure of lon protease from thermococcus onnurineus na1 Phyre2 PDB 2zro chain A Region: 59 - 276 Aligned: 216 Modelled: 218 Confidence: 100.0% Identity: 24% PDB header:hydrolase Chain: A: PDB Molecule:protein reca; PDBTitle: msreca adp form iv Phyre2 PDB 1xhk chain A Region: 293 - 460 Aligned: 168 Modelled: 168 Confidence: 100.0% Identity: 24% Fold: Ribosomal protein S5 domain 2-like Superfamily: Ribosomal protein S5 domain 2-like Family: ATP-dependent protease Lon (La), catalytic domain Phyre2 PDB 1z0e chain F Region: 292 - 460 Aligned: 169 Modelled: 169 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: F: PDB Molecule:putative protease la homolog type; PDBTitle: crystal structure of a. fulgidus lon proteolytic domain Phyre2 PDB 2x36 chain F Region: 294 - 457 Aligned: 159 Modelled: 164 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: F: PDB Molecule:lon protease homolog, mitochondrial; PDBTitle: structure of the proteolytic domain of the human2 mitochondrial lon protease Phyre2 PDB 2rec chain B Region: 59 - 272 Aligned: 211 Modelled: 214 Confidence: 100.0% Identity: 20% PDB header:helicase PDB COMPND: Phyre2 PDB 1rre chain A Region: 295 - 459 Aligned: 162 Modelled: 165 Confidence: 99.9% Identity: 23% Fold: Ribosomal protein S5 domain 2-like Superfamily: Ribosomal protein S5 domain 2-like Family: ATP-dependent protease Lon (La), catalytic domain Phyre2 PDB 1mo6 chain A domain 1 Region: 59 - 277 Aligned: 212 Modelled: 219 Confidence: 99.9% Identity: 23% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: RecA protein-like (ATPase-domain) Phyre2 PDB 1xp8 chain A domain 1 Region: 59 - 278 Aligned: 210 Modelled: 220 Confidence: 99.9% Identity: 22% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: RecA protein-like (ATPase-domain) Phyre2 PDB 2cvh chain B Region: 77 - 281 Aligned: 204 Modelled: 205 Confidence: 99.9% Identity: 23% PDB header:dna binding protein Chain: B: PDB Molecule:dna repair and recombination protein radb; PDBTitle: crystal structure of the radb recombinase Phyre2 PDB 3lda chain A Region: 72 - 279 Aligned: 194 Modelled: 208 Confidence: 99.9% Identity: 25% PDB header:dna binding protein Chain: A: PDB Molecule:dna repair protein rad51; PDBTitle: yeast rad51 h352y filament interface mutant Phyre2 PDB 1u94 chain A domain 1 Region: 59 - 277 Aligned: 211 Modelled: 219 Confidence: 99.9% Identity: 23% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: RecA protein-like (ATPase-domain) Phyre2 PDB 1tf7 chain A domain 1 Region: 70 - 289 Aligned: 214 Modelled: 220 Confidence: 99.9% Identity: 26% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: RecA protein-like (ATPase-domain) Phyre2 PDB 1xp8 chain A Region: 59 - 276 Aligned: 208 Modelled: 218 Confidence: 99.9% Identity: 22% PDB header:dna binding protein Chain: A: PDB Molecule:reca protein; PDBTitle: "deinococcus radiodurans reca in complex with atp-gamma-s" Phyre2 PDB 1tf7 chain A domain 2 Region: 70 - 296 Aligned: 220 Modelled: 227 Confidence: 99.9% Identity: 19% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: RecA protein-like (ATPase-domain) Phyre2 PDB 2q6t chain B Region: 66 - 270 Aligned: 198 Modelled: 205 Confidence: 99.9% Identity: 22% PDB header:hydrolase Chain: B: PDB Molecule:dnab replication fork helicase; PDBTitle: crystal structure of the thermus aquaticus dnab monomer Phyre2 PDB 1n0w chain A Region: 73 - 282 Aligned: 190 Modelled: 189 Confidence: 99.9% Identity: 24% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: RecA protein-like (ATPase-domain) Phyre2 PDB 2i1q chain A domain 2 Region: 70 - 279 Aligned: 208 Modelled: 210 Confidence: 99.9% Identity: 23% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: RecA protein-like (ATPase-domain) Phyre2 PDB 1szp chain A domain 2 Region: 72 - 279 Aligned: 199 Modelled: 203 Confidence: 99.9% Identity: 25% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: RecA protein-like (ATPase-domain) Phyre2 PDB 3cmw chain A Region: 59 - 222 Aligned: 162 Modelled: 162 Confidence: 99.6% Identity: 22% PDB header:recombination/dna Chain: A: PDB Molecule:protein reca; PDBTitle: mechanism of homologous recombination from the reca-2 ssdna/dsdna structures Phyre2 1 c3m6aC_ 2 c3k1jA_ 3 c2zroA_ 4 d1xhka_ 5 c1z0eF_ 6 c2x36F_ 7 c2recB_ 8 d1rrea_ 9 d1mo6a1 10 d1xp8a1 11 c2cvhB_ 12 c3ldaA_ 13 d1u94a1 14 d1tf7a1 15 c1xp8A_ 16 d1tf7a2 17 c2q6tB_ 18 d1n0wa_ 19 d2i1qa2 20 d1szpa2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 c3cmwA_ 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499