Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	E	S	K	R	L	D	N	A	A	L	A	A	G	I	S	P	N	Y	I	N	A	H	G	K	P	Q	S	I	S	A	E	T	K	R	R	L	L	D	A	M	H	Q	R	T	A	T	K	V	A	V	T	P	V	P	N	V	M	V	Y
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	S	G	K	K	M	P	M	V	V	E	G	S	G	E	Y	S	W	L	L	T	T	E	E	G	T	Q	Y	K	G	H	V	T	G	G	K	A	F	N	L	P	T	K	L	P	E	G	Y	H	T	L	T	L	T	Q	D	D	Q	R	A
Secondary structure
SS confidence
Disorder																																																									?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		H	C	R	V	I	V	A	P	K	R	C	Y	E	P	Q	A	L	L	N	K	Q	K	L	W	G	A	C	V	Q	L	Y	T	L	R	S	E	K	N	W	G	I	G	D	F	G	D	L	K	A	M	L	V	D	V	A	K	R	G	G	S
Secondary structure
SS confidence
Disorder										?	?	?	?		?	?	?	?	?	?														?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		F	I	G	L	N	P	I	H	A	L	Y	P	A	N	P	E	S	A	S	P	Y	S	P	S	S	R	R	W	L	N	V	I	Y	I	D	V	N	A	V	E	D	F	H	L	S	E	E	A	Q	A	W	W	Q	L	P	T	T	Q	Q	T
Secondary structure
SS confidence
Disorder														?																																					?	?	?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		L	Q	Q	A	R	D	A	D	W	V	D	Y	S	T	V	T	A	L	K	M	T	A	L	R	M	A	W	K	G	F	A	Q	R	D	D	E	Q	M	A	A	F	R	Q	F	V	A	E	Q	G	D	S	L	F	W	Q	A	A	F	D	A
Secondary structure
SS confidence
Disorder			?	?	?		?																										?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		L	H	A	Q	Q	V	K	E	D	E	M	R	W	G	W	P	A	W	P	E	M	Y	Q	N	V	D	S	P	E	V	R	Q	F	C	E	E	H	R	D	D	V	D	F	Y	L	W	L	Q	W	L	A	Y	S	Q	F	A	A	C	W	E
Secondary structure
SS confidence
Disorder								?	?	?	?	?	?		?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		I	S	Q	G	Y	E	M	P	I	G	L	Y	R	D	L	A	V	G	V	A	E	G	G	A	E	T	W	C	D	R	E	L	Y	C	L	K	A	S	V	G	A	P	P	D	I	L	G	P	L	G	Q	N	W	G	L	P	P	M	D	P
Secondary structure
SS confidence
Disorder						?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		H	I	I	T	A	R	A	Y	E	P	F	I	E	L	L	R	A	N	M	Q	N	C	G	A	L	R	I	D	H	V	M	S	M	L	R	L	W	W	I	P	Y	G	E	T	A	D	Q	G	A	Y	V	H	Y	P	V	D	D	L	L	S
Secondary structure
SS confidence
Disorder							?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		I	L	A	L	E	S	K	R	H	R	C	M	V	I	G	E	D	L	G	T	V	P	V	E	I	V	G	K	L	R	S	S	G	V	Y	S	Y	K	V	L	Y	F	E	N	D	H	E	K	T	F	R	A	P	K	A	Y	P	E	Q	S
Secondary structure
SS confidence
Disorder																																																?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence		M	A	V	A	A	T	H	D	L	P	T	L	R	G	Y	W	E	C	G	D	L	T	L	G	K	T	L	G	L	Y	P	D	E	V	V	L	R	G	L	Y	Q	D	R	E	L	A	K	Q	G	L	L	D	A	L	H	K	Y	G	C	L
Secondary structure
SS confidence
Disorder																																			?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660
Sequence		P	K	R	A	G	H	K	A	S	L	M	S	M	T	P	T	L	N	R	G	L	Q	R	Y	I	A	D	S	N	S	A	L	L	G	L	Q	P	E	D	W	L	D	M	A	E	P	V	N	I	P	G	T	S	Y	Q	Y	K	N	W	R
Secondary structure
SS confidence
Disorder																																														?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.
Sequence		R	K	L	S	A	T	L	E	S	M	F	A	D	D	G	V	N	K	L	L	K	D	L	D	R	R	R	R	A	A	A	K	K	K
Secondary structure
SS confidence
Disorder																										?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1x1n chain A domain 1 Region: 132 - 688 Aligned: 495 Modelled: 519 Confidence: 100.0% Identity: 23% Fold: TIM beta/alpha-barrel Superfamily: (Trans)glycosidases Family: Amylase, catalytic domain Phyre2 PDB 1esw chain A Region: 141 - 688 Aligned: 482 Modelled: 507 Confidence: 100.0% Identity: 25% Fold: TIM beta/alpha-barrel Superfamily: (Trans)glycosidases Family: Amylase, catalytic domain Phyre2 PDB 1tz7 chain A domain 1 Region: 142 - 682 Aligned: 469 Modelled: 486 Confidence: 100.0% Identity: 26% Fold: TIM beta/alpha-barrel Superfamily: (Trans)glycosidases Family: Amylase, catalytic domain Phyre2 PDB 3zt5 chain D Region: 155 - 689 Aligned: 309 Modelled: 325 Confidence: 98.6% Identity: 19% PDB header:hydrolase Chain: D: PDB Molecule:putative glucanohydrolase pep1a; PDBTitle: glge isoform 1 from streptomyces coelicolor with maltose2 bound Phyre2 PDB 3amk chain A Region: 155 - 689 Aligned: 343 Modelled: 363 Confidence: 98.4% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:os06g0726400 protein; PDBTitle: structure of the starch branching enzyme i (bei) from oryza sativa l Phyre2 PDB 3aml chain A Region: 150 - 689 Aligned: 353 Modelled: 369 Confidence: 98.3% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:os06g0726400 protein; PDBTitle: structure of the starch branching enzyme i (bei) from oryza sativa l Phyre2 PDB 1m53 chain A Region: 148 - 567 Aligned: 276 Modelled: 280 Confidence: 98.2% Identity: 18% PDB header:isomerase Chain: A: PDB Molecule:isomaltulose synthase; PDBTitle: crystal structure of isomaltulose synthase (pali) from2 klebsiella sp. lx3 Phyre2 PDB 1uok chain A domain 2 Region: 148 - 570 Aligned: 281 Modelled: 287 Confidence: 98.2% Identity: 19% Fold: TIM beta/alpha-barrel Superfamily: (Trans)glycosidases Family: Amylase, catalytic domain Phyre2 PDB 1j0h chain A domain 3 Region: 162 - 689 Aligned: 298 Modelled: 320 Confidence: 98.2% Identity: 16% Fold: TIM beta/alpha-barrel Superfamily: (Trans)glycosidases Family: Amylase, catalytic domain Phyre2 PDB 1uok chain A Region: 148 - 570 Aligned: 278 Modelled: 283 Confidence: 98.1% Identity: 21% PDB header:glucosidase Chain: A: PDB Molecule:oligo-1,6-glucosidase; PDBTitle: crystal structure of b. cereus oligo-1,6-glucosidase Phyre2 PDB 1bf2 chain A domain 3 Region: 148 - 694 Aligned: 381 Modelled: 400 Confidence: 98.1% Identity: 14% Fold: TIM beta/alpha-barrel Superfamily: (Trans)glycosidases Family: Amylase, catalytic domain Phyre2 PDB 1zja chain B Region: 148 - 567 Aligned: 272 Modelled: 280 Confidence: 98.1% Identity: 22% PDB header:isomerase Chain: B: PDB Molecule:trehalulose synthase; PDBTitle: crystal structure of the trehalulose synthase mutb from2 pseudomonas mesoacidophila mx-45 (triclinic form) Phyre2 PDB 1m53 chain A domain 2 Region: 148 - 567 Aligned: 276 Modelled: 280 Confidence: 98.0% Identity: 17% Fold: TIM beta/alpha-barrel Superfamily: (Trans)glycosidases Family: Amylase, catalytic domain Phyre2 PDB 1ua7 chain A domain 2 Region: 145 - 569 Aligned: 259 Modelled: 264 Confidence: 98.0% Identity: 20% Fold: TIM beta/alpha-barrel Superfamily: (Trans)glycosidases Family: Amylase, catalytic domain Phyre2 PDB 1gvi chain A domain 3 Region: 155 - 506 Aligned: 188 Modelled: 199 Confidence: 97.9% Identity: 20% Fold: TIM beta/alpha-barrel Superfamily: (Trans)glycosidases Family: Amylase, catalytic domain Phyre2 PDB 1wpc chain A Region: 145 - 550 Aligned: 248 Modelled: 259 Confidence: 97.9% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:glucan 1,4-alpha-maltohexaosidase; PDBTitle: crystal structure of maltohexaose-producing amylase complexed with2 pseudo-maltononaose Phyre2 PDB 3a47 chain A Region: 148 - 523 Aligned: 225 Modelled: 240 Confidence: 97.9% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:oligo-1,6-glucosidase; PDBTitle: crystal structure of isomaltase from saccharomyces cerevisiae Phyre2 PDB 1tcm chain B Region: 162 - 550 Aligned: 229 Modelled: 233 Confidence: 97.9% Identity: 21% PDB header:glycosyltransferase Chain: B: PDB Molecule:cyclodextrin glycosyltransferase; PDBTitle: cyclodextrin glycosyltransferase w616a mutant from bacillus2 circulans strain 251 Phyre2 PDB 1m7x chain A domain 3 Region: 154 - 503 Aligned: 182 Modelled: 201 Confidence: 97.9% Identity: 21% Fold: TIM beta/alpha-barrel Superfamily: (Trans)glycosidases Family: Amylase, catalytic domain Phyre2 PDB 1lwh chain A domain 2 Region: 148 - 507 Aligned: 197 Modelled: 206 Confidence: 97.9% Identity: 21% Fold: TIM beta/alpha-barrel Superfamily: (Trans)glycosidases Family: Amylase, catalytic domain Phyre2 PDB 2bno chain A Region: 5 - 46 Aligned: 42 Modelled: 42 Confidence: 75.9% Identity: 12% PDB header:oxidoreductase Chain: A: PDB Molecule:epoxidase; PDBTitle: the structure of hydroxypropylphosphonic acid epoxidase2 from s. wedmorenis. Phyre2 PDB 1j0h chain A domain 2 Region: 57 - 108 Aligned: 48 Modelled: 48 Confidence: 63.2% Identity: 21% Fold: Glycosyl hydrolase domain Superfamily: Glycosyl hydrolase domain Family: alpha-Amylases, C-terminal beta-sheet domain Phyre2 1 d1x1na1 2 d1eswa_ 3 d1tz7a1 4 c3zt5D_ 5 c3amkA_ 6 c3amlA_ 7 c1m53A_ 8 d1uoka2 9 d1j0ha3 10 c1uokA_ 11 d1bf2a3 12 c1zjaB_ 13 d1m53a2 14 d1ua7a2 15 d1gvia3 16 c1wpcA_ 17 c3a47A_ 18 c1tcmB_ 19 d1m7xa3 20 d1lwha2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 c2bnoA_ 107 108 109 110 d1j0ha2 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179