Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	M	N	D	G	K	Q	Q	S	T	F	L	F	H	D	Y	E	T	F	G	T	H	P	A	L	D	R	P	A	Q	F	A	A	I	R	T	D	S	E	F	N	V	I	G	E	P	E	V	F	Y	C	K	P	A	D	D	Y	L	P	Q
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																																	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	G	A	V	L	I	T	G	I	T	P	Q	E	A	R	A	K	G	E	N	E	A	A	F	A	A	R	I	H	S	L	F	T	V	P	K	T	C	I	L	G	Y	N	N	V	R	F	D	D	E	V	T	R	N	I	F	Y	R	N	F
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		Y	D	P	Y	A	W	S	W	Q	H	D	N	S	R	W	D	L	L	D	V	M	R	A	C	Y	A	L	R	P	E	G	I	N	W	P	E	N	D	D	G	L	P	S	F	R	L	E	H	L	T	K	A	N	G	I	E	H	S	N	A
Secondary structure
SS confidence
Disorder																																							?	?	?	?															?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		H	D	A	M	A	D	V	Y	A	T	I	A	M	A	K	L	V	K	T	R	Q	P	R	L	F	D	Y	L	F	T	H	R	N	K	H	K	L	M	A	L	I	D	V	P	Q	M	K	P	L	V	H	V	S	G	M	F	G	A	W	R
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		G	N	T	S	W	V	A	P	L	A	W	H	P	E	N	R	N	A	V	I	M	V	D	L	A	G	D	I	S	P	L	L	E	L	D	S	D	T	L	R	E	R	L	Y	T	A	K	T	D	L	G	D	N	A	A	V	P	V	K	L
Secondary structure
SS confidence
Disorder																																														?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		V	H	I	N	K	C	P	V	L	A	Q	A	N	T	L	R	P	E	D	A	D	R	L	G	I	N	R	Q	H	C	L	D	N	L	K	I	L	R	E	N	P	Q	V	R	E	K	V	V	A	I	F	A	E	A	E	P	F	T	P	S
Secondary structure
SS confidence
Disorder												?						?			?																			?															?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		D	N	V	D	A	Q	L	Y	N	G	F	F	S	D	A	D	R	A	A	M	K	I	V	L	E	T	E	P	R	N	L	P	A	L	D	I	T	F	V	D	K	R	I	E	K	L	L	F	N	Y	R	A	R	N	F	P	G	T	L	D
Secondary structure
SS confidence
Disorder		?	?							?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.
Sequence		Y	A	E	Q	Q	R	W	L	E	H	R	R	Q	V	F	T	P	E	F	L	Q	G	Y	A	D	E	L	Q	M	L	V	Q	Q	Y	A	D	D	K	E	K	V	A	L	L	K	A	L
Secondary structure
SS confidence
Disorder																																				?	?	?									?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2qxf chain A domain 1 Region: 8 - 467 Aligned: 425 Modelled: 441 Confidence: 100.0% Identity: 100% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: DnaQ-like 3'-5' exonuclease Phyre2 PDB 1y97 chain A domain 1 Region: 7 - 204 Aligned: 175 Modelled: 198 Confidence: 100.0% Identity: 16% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: DnaQ-like 3'-5' exonuclease Phyre2 PDB 1j9a chain A Region: 3 - 204 Aligned: 173 Modelled: 177 Confidence: 100.0% Identity: 18% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: DnaQ-like 3'-5' exonuclease Phyre2 PDB 2f96 chain A domain 1 Region: 6 - 204 Aligned: 179 Modelled: 179 Confidence: 100.0% Identity: 20% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: DnaQ-like 3'-5' exonuclease Phyre2 PDB 3b6o chain A domain 1 Region: 9 - 206 Aligned: 177 Modelled: 198 Confidence: 100.0% Identity: 18% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: DnaQ-like 3'-5' exonuclease Phyre2 PDB 3u6f chain A Region: 5 - 207 Aligned: 183 Modelled: 203 Confidence: 100.0% Identity: 17% PDB header:hydrolase/dna Chain: A: PDB Molecule:three prime repair exonuclease 1; PDBTitle: mouse trex1 d200n mutant Phyre2 PDB 3tr8 chain A Region: 5 - 204 Aligned: 171 Modelled: 178 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:oligoribonuclease; PDBTitle: structure of an oligoribonuclease (orn) from coxiella burnetii Phyre2 PDB 2igi chain A domain 1 Region: 5 - 204 Aligned: 171 Modelled: 177 Confidence: 100.0% Identity: 18% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: DnaQ-like 3'-5' exonuclease Phyre2 PDB 1w0h chain A Region: 9 - 204 Aligned: 179 Modelled: 196 Confidence: 100.0% Identity: 11% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: DnaQ-like 3'-5' exonuclease Phyre2 PDB 2gbz chain A Region: 8 - 199 Aligned: 163 Modelled: 172 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:oligoribonuclease; PDBTitle: the crystal structure of xc847 from xanthomonas campestris: a 3-52 oligoribonuclease of dnaq fold family with a novel opposingly-shifted3 helix Phyre2 PDB 3cm6 chain A Region: 9 - 200 Aligned: 178 Modelled: 192 Confidence: 100.0% Identity: 16% PDB header:hydrolase, apoptosis Chain: A: PDB Molecule:cell death-related nuclease 4; PDBTitle: crystal structure of cell-death related nuclease 4 (crn-4)2 bound with er Phyre2 PDB 2p1j chain B Region: 10 - 203 Aligned: 166 Modelled: 194 Confidence: 100.0% Identity: 20% PDB header:transferase Chain: B: PDB Molecule:dna polymerase iii polc-type; PDBTitle: crystal structure of a polc-type dna polymerase iii2 exonuclease domain from thermotoga maritima Phyre2 PDB 2xri chain A Region: 1 - 201 Aligned: 182 Modelled: 201 Confidence: 100.0% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:eri1 exoribonuclease 3; PDBTitle: crystal structure of human eri1 exoribonuclease 3 Phyre2 PDB 2gui chain A domain 1 Region: 11 - 198 Aligned: 165 Modelled: 188 Confidence: 100.0% Identity: 21% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: DnaQ-like 3'-5' exonuclease Phyre2 PDB 1zbh chain A Region: 9 - 200 Aligned: 172 Modelled: 192 Confidence: 100.0% Identity: 13% PDB header:hydrolase/rna Chain: A: PDB Molecule:3'-5' exonuclease eri1; PDBTitle: 3'-end specific recognition of histone mrna stem-loop by 3'-2 exonuclease Phyre2 PDB 1zbu chain B Region: 9 - 200 Aligned: 174 Modelled: 188 Confidence: 99.9% Identity: 11% PDB header:hydrolase Chain: B: PDB Molecule:3'-5' exonuclease eri1; PDBTitle: crystal structure of full-length 3'-exonuclease Phyre2 PDB 2is3 chain B Region: 2 - 200 Aligned: 156 Modelled: 189 Confidence: 99.9% Identity: 15% PDB header:hydrolase Chain: B: PDB Molecule:ribonuclease t; PDBTitle: crystal structure of escherichia coli rnase t Phyre2 PDB 1wlj chain A Region: 11 - 203 Aligned: 156 Modelled: 166 Confidence: 99.9% Identity: 16% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: DnaQ-like 3'-5' exonuclease Phyre2 PDB 1uoc chain A Region: 7 - 199 Aligned: 175 Modelled: 193 Confidence: 99.7% Identity: 14% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: CAF1-like ribonuclease Phyre2 PDB 2d5r chain A domain 1 Region: 10 - 202 Aligned: 179 Modelled: 193 Confidence: 99.5% Identity: 13% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: CAF1-like ribonuclease Phyre2 1 d2qxfa1 2 d1y97a1 3 d1j9aa_ 4 d2f96a1 5 d3b6oa1 6 c3u6fA_ 7 c3tr8A_ 8 d2igia1 9 d1w0ha_ 10 c2gbzA_ 11 c3cm6A_ 12 c2p1jB_ 13 c2xriA_ 14 d2guia1 15 c1zbhA_ 16 c1zbuB_ 17 c2is3B_ 18 d1wlja_ 19 d1uoca_ 20 d2d5ra1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d2qxfa1 100.0 100 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:DnaQ-like 3'-5' exonuclease 2 d1y97a1 100.0 16 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:DnaQ-like 3'-5' exonuclease 3 d1j9aa_ 100.0 18 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:DnaQ-like 3'-5' exonuclease 4 d2f96a1 100.0 20 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:DnaQ-like 3'-5' exonuclease 5 d3b6oa1 100.0 18 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:DnaQ-like 3'-5' exonuclease 6 c3u6fA_ 100.0 17 PDB header:hydrolase/dna Chain: A: PDB Molecule:three prime repair exonuclease 1; PDBTitle: mouse trex1 d200n mutant 7 c3tr8A_ 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:oligoribonuclease; PDBTitle: structure of an oligoribonuclease (orn) from coxiella burnetii 8 d2igia1 100.0 18 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:DnaQ-like 3'-5' exonuclease 9 d1w0ha_ 100.0 11 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:DnaQ-like 3'-5' exonuclease 10 c2gbzA_ 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:oligoribonuclease; PDBTitle: the crystal structure of xc847 from xanthomonas campestris: a 3-52 oligoribonuclease of dnaq fold family with a novel opposingly-shifted3 helix 11 c3cm6A_ 100.0 16 PDB header:hydrolase, apoptosis Chain: A: PDB Molecule:cell death-related nuclease 4; PDBTitle: crystal structure of cell-death related nuclease 4 (crn-4)2 bound with er 12 c2p1jB_ 100.0 20 PDB header:transferase Chain: B: PDB Molecule:dna polymerase iii polc-type; PDBTitle: crystal structure of a polc-type dna polymerase iii2 exonuclease domain from thermotoga maritima 13 c2xriA_ 100.0 14 PDB header:hydrolase Chain: A: PDB Molecule:eri1 exoribonuclease 3; PDBTitle: crystal structure of human eri1 exoribonuclease 3 14 d2guia1 100.0 21 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:DnaQ-like 3'-5' exonuclease 15 c1zbhA_ 100.0 13 PDB header:hydrolase/rna Chain: A: PDB Molecule:3'-5' exonuclease eri1; PDBTitle: 3'-end specific recognition of histone mrna stem-loop by 3'-2 exonuclease 16 c1zbuB_ 99.9 11 PDB header:hydrolase Chain: B: PDB Molecule:3'-5' exonuclease eri1; PDBTitle: crystal structure of full-length 3'-exonuclease 17 c2is3B_ 99.9 15 PDB header:hydrolase Chain: B: PDB Molecule:ribonuclease t; PDBTitle: crystal structure of escherichia coli rnase t 18 d1wlja_ 99.9 16 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:DnaQ-like 3'-5' exonuclease 19 d1uoca_ 99.7 14 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:CAF1-like ribonuclease 20 d2d5ra1 99.5 13 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:CAF1-like ribonuclease 21 c2p51A_ not modelled 99.4 17 PDB header:hydrolase, gene regulation Chain: A: PDB Molecule:spcc18.06c protein; PDBTitle: crystal structure of the s. pombe pop2p deadenylation2 subunit 22 d1x9ma1 not modelled 99.3 16 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:DnaQ-like 3'-5' exonuclease 23 d1kfsa1 not modelled 99.1 20 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:DnaQ-like 3'-5' exonuclease 24 c2kzzA_ not modelled 99.0 15 PDB header:transferase/dna Chain: A: PDB Molecule:protein (dna polymerase i); PDBTitle: klenow fragment with normal substrate and zinc only 25 d1qhta1 not modelled 99.0 16 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:DnaQ-like 3'-5' exonuclease 26 c1tk0A_ not modelled 98.9 15 PDB header:transferase/electron transport/dna Chain: A: PDB Molecule:dna polymerase; PDBTitle: t7 dna polymerase ternary complex with 8 oxo guanosine and2 ddctp at the insertion site 27 d1wn7a1 not modelled 98.9 19 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:DnaQ-like 3'-5' exonuclease 28 c2gv9B_ not modelled 98.9 15 PDB header:transferase Chain: B: PDB Molecule:dna polymerase; PDBTitle: crystal structure of the herpes simplex virus type 1 dna polymerase 29 d1tgoa1 not modelled 98.9 19 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:DnaQ-like 3'-5' exonuclease 30 c2a1sC_ not modelled 98.8 23 PDB header:hydrolase Chain: C: PDB Molecule:poly(a)-specific ribonuclease parn; PDBTitle: crystal structure of native parn nuclease domain 31 c3d45B_ not modelled 98.8 20 PDB header:hydrolase Chain: B: PDB Molecule:poly(a)-specific ribonuclease parn; PDBTitle: crystal structure of mouse parn in complex with m7gpppg 32 c3iayA_ not modelled 98.7 21 PDB header:transferase/dna Chain: A: PDB Molecule:dna polymerase delta catalytic subunit; PDBTitle: ternary complex of dna polymerase delta 33 d1d5aa1 not modelled 98.7 18 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:DnaQ-like 3'-5' exonuclease 34 d2hhva1 not modelled 98.7 12 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:DnaQ-like 3'-5' exonuclease 35 c1njzA_ not modelled 98.6 17 PDB header:transferase/dna Chain: A: PDB Molecule:dna polymerase i; PDBTitle: cytosine-thymine mismatch at the polymerase active site 36 c2vwkA_ not modelled 98.5 18 PDB header:dna replication Chain: A: PDB Molecule:dna polymerase; PDBTitle: uracil recognition in archaeal dna polymerases captured by2 x-ray crystallography. v93q polymerase variant 37 c1d5aA_ not modelled 98.4 20 PDB header:transferase Chain: A: PDB Molecule:protein (dna polymerase); PDBTitle: crystal structure of an archaebacterial dna polymerase2 d.tok. deposition of second native structure at 2.43 angstrom 38 d1ih7a1 not modelled 98.4 14 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:DnaQ-like 3'-5' exonuclease 39 d1s5ja1 not modelled 98.4 12 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:DnaQ-like 3'-5' exonuclease 40 d1noya_ not modelled 98.3 18 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:DnaQ-like 3'-5' exonuclease 41 c1s5jA_ not modelled 98.1 12 PDB header:transferase Chain: A: PDB Molecule:dna polymerase i; PDBTitle: insight in dna replication: the crystal structure of dna2 polymerase b1 from the archaeon sulfolobus solfataricus 42 d1q8ia1 not modelled 98.1 15 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:DnaQ-like 3'-5' exonuclease 43 c2dtuA_ not modelled 98.1 13 PDB header:transferase/dna Chain: A: PDB Molecule:dna polymerase; PDBTitle: crystal structure of the beta hairpin loop deletion variant2 of rb69 gp43 in complex with dna containing an abasic site3 analog 44 c4ktqA_ not modelled 98.1 18 PDB header:transferase/dna Chain: A: PDB Molecule:protein (large fragment of dna polymerase i); PDBTitle: binary complex of the large fragment of dna polymerase i2 from t. aquaticus bound to a primer/template dna 45 c1q8iA_ not modelled 97.9 18 PDB header:transferase Chain: A: PDB Molecule:dna polymerase ii; PDBTitle: crystal structure of escherichia coli dna polymerase ii 46 c1yt3A_ not modelled 97.4 18 PDB header:hydrolase,translation Chain: A: PDB Molecule:ribonuclease d; PDBTitle: crystal structure of escherichia coli rnase d, an2 exoribonuclease involved in structured rna processing 47 d1yt3a3 not modelled 97.2 16 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:DnaQ-like 3'-5' exonuclease 48 d2hbka2 not modelled 97.1 19 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:DnaQ-like 3'-5' exonuclease 49 c2e6mA_ not modelled 96.9 14 PDB header:hydrolase Chain: A: PDB Molecule:werner syndrome atp-dependent helicase homolog; PDBTitle: structure of mouse werner exonuclease domain 50 c2hbkA_ not modelled 93.2 19 PDB header:hydrolase, gene regulation Chain: A: PDB Molecule:exosome complex exonuclease rrp6; PDBTitle: structure of the yeast nuclear exosome component, rrp6p,2 reveals an interplay between the active site and the hrdc3 domain; protein in complex with mn 51 c3cymA_ not modelled 92.5 24 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein bad_0989; PDBTitle: crystal structure of protein bad_0989 from bifidobacterium2 adolescentis 52 c1cmwA_ not modelled 76.5 19 PDB header:transferase Chain: A: PDB Molecule:protein (dna polymerase i); PDBTitle: crystal structure of taq dna-polymerase shows a new2 orientation for the structure-specific nuclease domain 53 c3ikmD_ not modelled 72.1 29 PDB header:transferase Chain: D: PDB Molecule:dna polymerase subunit gamma-1; PDBTitle: crystal structure of human mitochondrial dna polymerase2 holoenzyme 54 d1vk0a_ not modelled 70.2 12 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:DnaQ-like 3'-5' exonuclease 55 c3sahA_ not modelled 60.9 22 PDB header:hydrolase Chain: A: PDB Molecule:exosome component 10; PDBTitle: crystal structure of the human rrp6 catalytic domain with y436a2 mutation in the catalytic site 56 c3iykA_ not modelled 52.2 19 PDB header:virus Chain: A: PDB Molecule:vp5; PDBTitle: bluetongue virus structure reveals a sialic acid binding domain,2 amphipathic helices and a central coiled coil in the outer capsid3 proteins 57 d2py5a1 not modelled 49.9 17 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:DnaQ-like 3'-5' exonuclease 58 d1bh9b_ not modelled 34.2 14 Fold:Histone-fold Superfamily:Histone-fold Family:TBP-associated factors, TAFs 59 c3nrwA_ not modelled 30.7 19 PDB header:recombination Chain: A: PDB Molecule:phage integrase/site-specific recombinase; PDBTitle: crystal structure of the n-terminal domain of phage integrase/site-2 specific recombinase (tnp) from haloarcula marismortui, northeast3 structural genomics consortium target hmr208a 60 c3fleB_ not modelled 28.6 20 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:se_1780 protein; PDBTitle: se_1780 protein of unknown function from staphylococcus epidermidis. 61 c3fp5A_ not modelled 26.4 20 PDB header:lipid binding protein Chain: A: PDB Molecule:acyl-coa binding protein; PDBTitle: crystal structure of acbp from moniliophthora perniciosa 62 d1xkla_ not modelled 23.5 23 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Hydroxynitrile lyase-like 63 c3p2mA_ not modelled 14.4 19 PDB header:hydrolase Chain: A: PDB Molecule:possible hydrolase; PDBTitle: crystal structure of a novel esterase rv0045c from mycobacterium2 tuberculosis 64 c3lp5A_ not modelled 13.1 16 PDB header:hydrolase Chain: A: PDB Molecule:putative cell surface hydrolase; PDBTitle: the crystal structure of the putative cell surface hydrolase from2 lactobacillus plantarum wcfs1 65 c2ex3I_ not modelled 13.0 17 PDB header:transferase/replication Chain: I: PDB Molecule:dna polymerase; PDBTitle: bacteriophage phi29 dna polymerase bound to terminal protein 66 c1pjaA_ not modelled 13.0 25 PDB header:hydrolase Chain: A: PDB Molecule:palmitoyl-protein thioesterase 2 precursor; PDBTitle: the crystal structure of palmitoyl protein thioesterase-2 reveals the2 basis for divergent substrate specificities of the two lysosomal3 thioesterases (ppt1 and ppt2) 67 d1pjaa_ not modelled 13.0 25 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Thioesterases 68 c3e3aA_ not modelled 10.2 26 PDB header:oxidoreductase Chain: A: PDB Molecule:possible peroxidase bpoc; PDBTitle: the structure of rv0554 from mycobacterium tuberculosis 69 d1q0ra_ not modelled 10.0 22 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Aclacinomycin methylesterase RdmC 70 d2rhwa1 not modelled 9.8 13 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carbon-carbon bond hydrolase 71 d1m0da_ not modelled 9.6 29 Fold:Restriction endonuclease-like Superfamily:Restriction endonuclease-like Family:Endonuclease I (Holliday junction resolvase) 72 c3ds8A_ not modelled 9.1 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:lin2722 protein; PDBTitle: the crysatl structure of the gene lin2722 products from listeria2 innocua 73 c2y6vB_ not modelled 8.9 15 PDB header:hydrolase Chain: B: PDB Molecule:peroxisomal membrane protein lpx1; PDBTitle: peroxisomal alpha-beta-hydrolase lpx1 (yor084w) from2 saccharomyces cerevisiae (crystal form i) 74 c3nwoA_ not modelled 8.7 32 PDB header:hydrolase Chain: A: PDB Molecule:proline iminopeptidase; PDBTitle: crystal structure of proline iminopeptidase mycobacterium smegmatis 75 c3fsgC_ not modelled 8.6 19 PDB header:hydrolase Chain: C: PDB Molecule:alpha/beta superfamily hydrolase; PDBTitle: crystal structure of alpha/beta superfamily hydrolase from oenococcus2 oeni psu-1 76 d1brta_ not modelled 7.2 24 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloperoxidase 77 d1tqha_ not modelled 7.1 10 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase/lipase 78 c2k9qB_ not modelled 7.0 22 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: solution nmr structure of hth_xre family transcriptional2 regulator bt_p548217 from bacteroides thetaiotaomicron.3 northeast structural genomics consortium target btr244. 79 d1s2da_ not modelled 6.9 33 Fold:Flavodoxin-like Superfamily:N-(deoxy)ribosyltransferase-like Family:N-deoxyribosyltransferase 80 c2d3wB_ not modelled 6.9 13 PDB header:biosynthetic protein Chain: B: PDB Molecule:probable atp-dependent transporter sufc; PDBTitle: crystal structure of escherichia coli sufc, an atpase2 compenent of the suf iron-sulfur cluster assembly machinery 81 c3tovB_ not modelled 6.8 17 PDB header:transferase Chain: B: PDB Molecule:glycosyl transferase family 9; PDBTitle: the crystal structure of the glycosyl transferase family 9 from2 veillonella parvula dsm 2008 82 c2px6A_ not modelled 6.7 19 PDB header:transferase Chain: A: PDB Molecule:thioesterase domain; PDBTitle: crystal structure of the thioesterase domain of human fatty2 acid synthase inhibited by orlistat 83 d1mj5a_ not modelled 6.6 20 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloalkane dehalogenase 84 c2voyD_ not modelled 6.5 57 PDB header:hydrolase Chain: D: PDB Molecule:sarcoplasmic/endoplasmic reticulum calcium PDBTitle: cryoem model of copa, the copper transporting atpase from2 archaeoglobus fulgidus 85 c2r6fA_ not modelled 6.4 23 PDB header:hydrolase Chain: A: PDB Molecule:excinuclease abc subunit a; PDBTitle: crystal structure of bacillus stearothermophilus uvra 86 c2h1fB_ not modelled 6.4 21 PDB header:transferase Chain: B: PDB Molecule:lipopolysaccharide heptosyltransferase-1; PDBTitle: e. coli heptosyltransferase waac with adp 87 c2zyiB_ not modelled 6.3 20 PDB header:hydrolase Chain: B: PDB Molecule:lipase, putative; PDBTitle: a. fulgidus lipase with fatty acid fragment and calcium 88 c3hhjA_ not modelled 6.0 11 PDB header:hydrolase Chain: A: PDB Molecule:mutator mutt protein; PDBTitle: crystal structure of mutator mutt from bartonella henselae 89 d1z67a1 not modelled 6.0 21 Fold:YidB-like Superfamily:YidB-like Family:YidB-like 90 d1j6ua3 not modelled 5.9 9 Fold:Ribokinase-like Superfamily:MurD-like peptide ligases, catalytic domain Family:MurCDEF 91 c2pseA_ not modelled 5.8 15 PDB header:oxidoreductase Chain: A: PDB Molecule:renilla-luciferin 2-monooxygenase; PDBTitle: crystal structures of the luciferase and green fluorescent2 protein from renilla reniformis 92 c3r0vA_ not modelled 5.6 23 PDB header:hydrolase Chain: A: PDB Molecule:alpha/beta hydrolase fold protein; PDBTitle: the crystal structure of an alpha/beta hydrolase from sphaerobacter2 thermophilus dsm 20745. 93 c3r03B_ not modelled 5.5 9 PDB header:hydrolase Chain: B: PDB Molecule:nudix hydrolase; PDBTitle: the crystal structure of nudix hydrolase from rhodospirillum rubrum 94 d1gm5a1 not modelled 5.5 21 Fold:Four-helical up-and-down bundle Superfamily:RecG, N-terminal domain Family:RecG, N-terminal domain 95 d1zd3a2 not modelled 5.5 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Epoxide hydrolase 96 c2qvbA_ not modelled 5.2 17 PDB header:hydrolase Chain: A: PDB Molecule:haloalkane dehalogenase 3; PDBTitle: crystal structure of haloalkane dehalogenase rv2579 from mycobacterium2 tuberculosis 97 c3bf7B_ not modelled 5.2 28 PDB header:hydrolase Chain: B: PDB Molecule:esterase ybff; PDBTitle: 1.1 resolution structure of ybff, a new esterase from2 escherichia coli: a unique substrate-binding crevice3 generated by domain arrangement 98 d1pswa_ not modelled 5.1 14 Fold:UDP-Glycosyltransferase/glycogen phosphorylase Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase Family:ADP-heptose LPS heptosyltransferase II 99 d1uk8a_ not modelled 5.1 20 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carbon-carbon bond hydrolase

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0