PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c1pjaA_

Fold library id	PDB Header	Molecule	Title
c1pjaA_	PDB header: hydrolase	Chain: A: PDB Molecule: palmitoyl-protein thioesterase 2 precursor;	PDBTitle: the crystal structure of palmitoyl protein thioesterase-22 reveals the basis for divergent substrate specificities of3 the two lysosomal thioesterases (ppt1 and ppt2)

Links to external resources
Added to library: Tue Mar 16 12:08:37 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence S Y K P V I V V H G L F D S S Y S F R H L L E Y I N E T H P G T V V T V L D L F D G R E S L R P L W E Q V Q G F R E A V V P I M A K A P Q G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
G G G G S T T
S S
S G G G G S
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence V H L I C Y S Q G G L V C R A L L S V M D D H N V D S F I S L S S P Q M G Q Y G D T D Y L K W L F P T S M R S N L Y R I C Y S P W G Q E F S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T T
S
T T
B
S
T T
T S T T G G G S T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence I C N Y W H D P H H D D L Y L N A S S F L A L I N G E R D H P N A T V W R K N F L R V G H L V L I G G P D D G V I T P W Q S S F F G F Y D A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G G G B
T T
S S T T S S
T T T T
S
T T
S S S S S G G G G G T
T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . .

Sequence N E T V L E M E E Q L V Y L R D S F G L K T L L A R G A I V R C P M A G I S H T A W H S N R T L Y E T C I E P W L S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
G G G S T T T T S T T
S S
T T T T T S
T G G G

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	S	Y	K	P	V	I	V	V	H	G	L	F	D	S	S	Y	S	F	R	H	L	L	E	Y	I	N	E	T	H	P	G	T	V	V	T	V	L	D	L	F	D	G	R	E	S	L	R	P	L	W	E	Q	V	Q	G	F	R	E	A	V	V	P	I	M	A	K	A	P	Q	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											T	T			G	G	G	G											S	T	T								S	S		S	G	G	G	G	S																					T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	V	H	L	I	C	Y	S	Q	G	G	L	V	C	R	A	L	L	S	V	M	D	D	H	N	V	D	S	F	I	S	L	S	S	P	Q	M	G	Q	Y	G	D	T	D	Y	L	K	W	L	F	P	T	S	M	R	S	N	L	Y	R	I	C	Y	S	P	W	G	Q	E	F	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							T														T	T										S			T	T		B		S										T	T											T	S	T	T	G	G	G	S	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	I	C	N	Y	W	H	D	P	H	H	D	D	L	Y	L	N	A	S	S	F	L	A	L	I	N	G	E	R	D	H	P	N	A	T	V	W	R	K	N	F	L	R	V	G	H	L	V	L	I	G	G	P	D	D	G	V	I	T	P	W	Q	S	S	F	F	G	F	Y	D	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G	G	G	G	B			T	T										S	S					T	T	S	S			T	T									T	T		S								T	T		S	S	S	S	S	G	G	G	G	G	T					T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.
Sequence	N	E	T	V	L	E	M	E	E	Q	L	V	Y	L	R	D	S	F	G	L	K	T	L	L	A	R	G	A	I	V	R	C	P	M	A	G	I	S	H	T	A	W	H	S	N	R	T	L	Y	E	T	C	I	E	P	W	L	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T						G	G	G	S					T	T	T	T	S							T	T								S	S			T	T	T	T	T	S									T	G	G	G