PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2px6A_

Fold library id	PDB Header	Molecule	Title
c2px6A_	PDB header: transferase	Chain: A: PDB Molecule: thioesterase domain;	PDBTitle: crystal structure of the thioesterase domain of human fatty2 acid synthase inhibited by orlistat

Links to external resources
Added to library: Tue Mar 16 14:09:31 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence S L L V N P E G P T L M R L N S V Q S S E R P L F L V H P I E G S T T V F H S L A S R L S I P T Y G L Q C T R A A P L D S I H S L A A Y Y I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S
S S
S S
T T
S G G G
S S
T T S
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence D C I R Q V Q P E G P Y R V A G Y S Y G A C V A F E M C S Q L Q A Q Q P T H N S L F L F D G S P T Y A E A E T E A I C F F V Q Q F T D M E H

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T
S S
T
S
S S
S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence N R V L E A L L P L K G L E E R V A A A V D L I I K S H Q G L D R Q E L S F A A R S F Y Y K L R A A E Q Y T P K A K Y H G N V M L L R A K T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
S
T T S
T
S
B
S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . .

Sequence G A D Y N L S Q V C D G K V S V H V I E G D H R T L L E G S G L E S I I S I I H S S L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T T T T T T B
S
S S
T T G G G S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	S	L	L	V	N	P	E	G	P	T	L	M	R	L	N	S	V	Q	S	S	E	R	P	L	F	L	V	H	P	I	E	G	S	T	T	V	F	H	S	L	A	S	R	L	S	I	P	T	Y	G	L	Q	C	T	R	A	A	P	L	D	S	I	H	S	L	A	A	Y	Y	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T	T	S		S				S						S	S									T	T			S	G	G	G								S	S									T	T	S		T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	D	C	I	R	Q	V	Q	P	E	G	P	Y	R	V	A	G	Y	S	Y	G	A	C	V	A	F	E	M	C	S	Q	L	Q	A	Q	Q	P	T	H	N	S	L	F	L	F	D	G	S	P	T	Y	A	E	A	E	T	E	A	I	C	F	F	V	Q	Q	F	T	D	M	E	H
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	T	T		S	S									T																											S		S	S																		S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	N	R	V	L	E	A	L	L	P	L	K	G	L	E	E	R	V	A	A	A	V	D	L	I	I	K	S	H	Q	G	L	D	R	Q	E	L	S	F	A	A	R	S	F	Y	Y	K	L	R	A	A	E	Q	Y	T	P	K	A	K	Y	H	G	N	V	M	L	L	R	A	K	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T	T	S		S																	T	T	S																					T					S		B		S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.
Sequence	G	A	D	Y	N	L	S	Q	V	C	D	G	K	V	S	V	H	V	I	E	G	D	H	R	T	L	L	E	G	S	G	L	E	S	I	I	S	I	I	H	S	S	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T	T	T	T	T	T	T	B		S								S	S		T	T	G	G	G	S