Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionA0PJM3
DateTue Apr 3 14:51:25 BST 2012
Unique Job IDc4985a30697b406b

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1wlja_
Top template information
Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
Confidence and coverage
Confidence: 99.9% Coverage: 27%
156 residues ( 27% of your sequence) have been modelled with 99.9% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
277 residues ( 48%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MLRATAPCWFPPGYPEAKKVAEEAALEAPEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQ
Secondary structure 
















































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Disorder  ????????



?
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   .........70.........80.........90.........100.........110.........120
Sequence  AEPQNRGPAVPPAWPKMVTESCYFPAQRGSACRLPAAPRLTERPSGVRISAPRKRKTIAH
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Disorder  ????????????????????????????????????????????????????????????
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   .........130.........140.........150.........160.........170.........180
Sequence  SSSPCLVTGYTDAKRTRVASSSQRSRGSKVGRQPGKTRNRSGMACKTTATTSSKRIVRRA
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Disorder  ????????????????????????????????????????????????????????????
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   .........190.........200.........210.........220.........230.........240
Sequence  SLPSLSLKKPIILRSSGCQVPTVLRRGYLQLFTEECLKFCASKQEAEEKALNEEKVAYDC
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Disorder  ??????????????????
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?
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   .........250.........260.........270.........280.........290.........300
Sequence  SPNKNRYLNVVLNTLKRLKGLTPSSMPGLSRAALYSRLQEFLLTQDQLKENGYPFPHPER
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   .........310.........320.........330.........340.........350.........360
Sequence  PGGAVLFTGQGKGPGDSSCRVCCRCGTEYLVSSSGRCVRDQLCYYHWGRVRSSQVAGGRV
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Disorder  ?





????????????



??????????????
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?

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   .........370.........380.........390.........400.........410.........420
Sequence  SQYTCCAAAPGSVGCQVAKQHVRDGRKESLDGFVETFKKELSRDAYPGIYALDCEMCYTT
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Disorder 





???????







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   .........430.........440.........450.........460.........470.........480
Sequence  HGLELTRVTVVDADMRVVYDTFVKPDNEIVDYNTRFSGVTEADVAKTSITLPQVQAILLS
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   .........490.........500.........510.........520.........530.........540
Sequence  FFSAQTILIGHSLESDLLALKLIHSTVVDTAVLFPHYLGFPYKRSLRNLAADYLAQIIQD
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??????















?
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   .........550.........560.........570.........580...
Sequence  SQDGHNSSEDANACLQLVMWKVRQRAQIQPRHRSASPAALACP
Secondary structure 
















SS confidence 










































Disorder  ????




















??????????????????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1wlj chain A

3D model

Region: 409 - 567
Aligned: 156
Modelled: 159
Confidence: 99.9%
Identity: 35%
Fold: Ribonuclease H-like motif
Superfamily: Ribonuclease H-like
Family: DnaQ-like 3'-5' exonuclease

Phyre2

PDB 2gui chain A domain 1

3D model

Region: 408 - 561
Aligned: 149
Modelled: 154
Confidence: 99.7%
Identity: 19%
Fold: Ribonuclease H-like motif
Superfamily: Ribonuclease H-like
Family: DnaQ-like 3'-5' exonuclease

Phyre2

PDB 2igi chain A domain 1

3D model

Region: 408 - 568
Aligned: 147
Modelled: 148
Confidence: 99.6%
Identity: 19%
Fold: Ribonuclease H-like motif
Superfamily: Ribonuclease H-like
Family: DnaQ-like 3'-5' exonuclease

Phyre2

PDB 1j9a chain A

3D model

Region: 400 - 569
Aligned: 158
Modelled: 170
Confidence: 99.6%
Identity: 16%
Fold: Ribonuclease H-like motif
Superfamily: Ribonuclease H-like
Family: DnaQ-like 3'-5' exonuclease

Phyre2

PDB 2p1j chain B

3D model

Region: 410 - 573
Aligned: 156
Modelled: 161
Confidence: 99.5%
Identity: 21%
PDB header:transferase
Chain: B: PDB Molecule:dna polymerase iii polc-type;
PDBTitle: crystal structure of a polc-type dna polymerase iii2 exonuclease domain from thermotoga maritima

Phyre2

PDB 2gbz chain A

3D model

Region: 406 - 563
Aligned: 144
Modelled: 158
Confidence: 99.5%
Identity: 17%
PDB header:hydrolase
Chain: A: PDB Molecule:oligoribonuclease;
PDBTitle: the crystal structure of xc847 from xanthomonas campestris: a 3-52 oligoribonuclease of dnaq fold family with a novel opposingly-shifted3 helix

Phyre2

PDB 3tr8 chain A

3D model

Region: 408 - 568
Aligned: 148
Modelled: 161
Confidence: 99.5%
Identity: 20%
PDB header:hydrolase
Chain: A: PDB Molecule:oligoribonuclease;
PDBTitle: structure of an oligoribonuclease (orn) from coxiella burnetii

Phyre2

PDB 3cm6 chain A

3D model

Region: 408 - 568
Aligned: 156
Modelled: 161
Confidence: 99.5%
Identity: 14%
PDB header:hydrolase, apoptosis
Chain: A: PDB Molecule:cell death-related nuclease 4;
PDBTitle: crystal structure of cell-death related nuclease 4 (crn-4)2 bound with er

Phyre2

PDB 1w0h chain A

3D model

Region: 408 - 573
Aligned: 162
Modelled: 166
Confidence: 99.5%
Identity: 15%
Fold: Ribonuclease H-like motif
Superfamily: Ribonuclease H-like
Family: DnaQ-like 3'-5' exonuclease

Phyre2

PDB 1zbh chain A

3D model

Region: 409 - 570
Aligned: 158
Modelled: 162
Confidence: 99.5%
Identity: 16%
PDB header:hydrolase/rna
Chain: A: PDB Molecule:3'-5' exonuclease eri1;
PDBTitle: 3'-end specific recognition of histone mrna stem-loop by 3'-2 exonuclease

Phyre2

PDB 2xri chain A

3D model

Region: 402 - 569
Aligned: 163
Modelled: 168
Confidence: 99.4%
Identity: 17%
PDB header:hydrolase
Chain: A: PDB Molecule:eri1 exoribonuclease 3;
PDBTitle: crystal structure of human eri1 exoribonuclease 3

Phyre2

PDB 1y97 chain A domain 1

3D model

Region: 401 - 564
Aligned: 157
Modelled: 164
Confidence: 99.4%
Identity: 15%
Fold: Ribonuclease H-like motif
Superfamily: Ribonuclease H-like
Family: DnaQ-like 3'-5' exonuclease

Phyre2

PDB 2f96 chain A domain 1

3D model

Region: 409 - 564
Aligned: 151
Modelled: 155
Confidence: 99.3%
Identity: 19%
Fold: Ribonuclease H-like motif
Superfamily: Ribonuclease H-like
Family: DnaQ-like 3'-5' exonuclease

Phyre2

PDB 3u6f chain A

3D model

Region: 402 - 564
Aligned: 160
Modelled: 163
Confidence: 99.3%
Identity: 20%
PDB header:hydrolase/dna
Chain: A: PDB Molecule:three prime repair exonuclease 1;
PDBTitle: mouse trex1 d200n mutant

Phyre2

PDB 3b6o chain A domain 1

3D model

Region: 409 - 564
Aligned: 152
Modelled: 155
Confidence: 99.3%
Identity: 20%
Fold: Ribonuclease H-like motif
Superfamily: Ribonuclease H-like
Family: DnaQ-like 3'-5' exonuclease

Phyre2

PDB 1zbu chain B

3D model

Region: 409 - 570
Aligned: 158
Modelled: 162
Confidence: 99.3%
Identity: 16%
PDB header:hydrolase
Chain: B: PDB Molecule:3'-5' exonuclease eri1;
PDBTitle: crystal structure of full-length 3'-exonuclease

Phyre2

PDB 2qxf chain A domain 1

3D model

Region: 407 - 568
Aligned: 155
Modelled: 162
Confidence: 99.2%
Identity: 15%
Fold: Ribonuclease H-like motif
Superfamily: Ribonuclease H-like
Family: DnaQ-like 3'-5' exonuclease

Phyre2

PDB 2is3 chain B

3D model

Region: 410 - 575
Aligned: 147
Modelled: 165
Confidence: 98.6%
Identity: 16%
PDB header:hydrolase
Chain: B: PDB Molecule:ribonuclease t;
PDBTitle: crystal structure of escherichia coli rnase t

Phyre2

PDB 1kfs chain A domain 1

3D model

Region: 408 - 564
Aligned: 141
Modelled: 141
Confidence: 98.3%
Identity: 18%
Fold: Ribonuclease H-like motif
Superfamily: Ribonuclease H-like
Family: DnaQ-like 3'-5' exonuclease

Phyre2

PDB 2e6m chain A

3D model

Region: 408 - 566
Aligned: 132
Modelled: 133
Confidence: 98.3%
Identity: 16%
PDB header:hydrolase
Chain: A: PDB Molecule:werner syndrome atp-dependent helicase homolog;
PDBTitle: structure of mouse werner exonuclease domain

Phyre2

PDB 2xcm chain E

3D model

Region: 320 - 380
Aligned: 53
Modelled: 53
Confidence: 97.5%
Identity: 21%
PDB header:chaperone/protein binding
Chain: E: PDB Molecule:rar1;
PDBTitle: complex of hsp90 n-terminal, sgt1 cs and rar1 chord2 domain

Phyre2

PDB 2yrt chain A

3D model

Region: 317 - 380
Aligned: 56
Modelled: 56
Confidence: 97.2%
Identity: 27%
PDB header:transcription
Chain: A: PDB Molecule:chord containing protein-1;
PDBTitle: solution structure of the chord domain of human chord-2 containing protein 1

Phyre2

PDB 2k0n chain A

3D model

Region: 195 - 259
Aligned: 65
Modelled: 65
Confidence: 95.3%
Identity: 11%
PDB header:transcription
Chain: A: PDB Molecule:mediator of rna polymerase ii transcription
PDBTitle: solution structure of yeast gal11p kix domain

Phyre2

PDB 2e6i chain A

3D model

Region: 345 - 407
Aligned: 47
Modelled: 47
Confidence: 84.2%
Identity: 15%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase itk/tsk;
PDBTitle: solution structure of the btk motif of tyrosine-protein2 kinase itk from human

Phyre2

PDB 1i6v chain D

3D model

Region: 282 - 348
Aligned: 42
Modelled: 42
Confidence: 78.7%
Identity: 31%
PDB header:transcription
Chain: D: PDB Molecule:dna-directed rna polymerase;
PDBTitle: thermus aquaticus core rna polymerase-rifampicin complex

Phyre2

PDB 1i6v chain D

3D model

Region: 282 - 348
Aligned: 42
Modelled: 42
Confidence: 78.7%
Identity: 31%
Fold: beta and beta-prime subunits of DNA dependent RNA-polymerase
Superfamily: beta and beta-prime subunits of DNA dependent RNA-polymerase
Family: RNA-polymerase beta-prime

Phyre2

PDB 1ynj chain D domain 1

3D model

Region: 282 - 348
Aligned: 59
Modelled: 59
Confidence: 76.4%
Identity: 29%
Fold: beta and beta-prime subunits of DNA dependent RNA-polymerase
Superfamily: beta and beta-prime subunits of DNA dependent RNA-polymerase
Family: RNA-polymerase beta-prime

Phyre2
1

d1wlja_
2

d2guia1
3

d2igia1
4

d1j9aa_
5

c2p1jB_
6

c2gbzA_
7

c3tr8A_
8

c3cm6A_
9

d1w0ha_
10

c1zbhA_
11

c2xriA_
12

d1y97a1
13

d2f96a1
14

c3u6fA_
15

d3b6oa1
16

c1zbuB_
17

d2qxfa1
18

c2is3B_
19

d1kfsa1
20

c2e6mA_
21



22



23



24

c2xcmE_
25



26



27



28



29

c2yrtA_
30



31



32



33



34



35



36



37



38

c2k0nA_
39



40



41



42



43



44



45



46



47



48



49



50



51



52



53



54



55



56

c2e6iA_
57



58



59



60

c1i6vD_
61

d1i6vd_
62

d1ynjd1
63



64



65



66



67



68



69



70



71



72



73



74



75



76



77



78



79



80



81



82



83



84



85



86



87



88



89



90



91



92



93



94



95



96



97



98



99



100



101



102



103



104



105



106



107



108



109



110



111



112






Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1wlja_



99.9 35 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
2d2guia1



99.7 19 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
3d2igia1



99.6 19 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
4d1j9aa_



99.6 16 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
5c2p1jB_



99.5 21 PDB header:transferase
Chain: B: PDB Molecule:dna polymerase iii polc-type;
PDBTitle: crystal structure of a polc-type dna polymerase iii2 exonuclease domain from thermotoga maritima
6c2gbzA_



99.5 17 PDB header:hydrolase
Chain: A: PDB Molecule:oligoribonuclease;
PDBTitle: the crystal structure of xc847 from xanthomonas campestris: a 3-52 oligoribonuclease of dnaq fold family with a novel opposingly-shifted3 helix
7c3tr8A_



99.5 20 PDB header:hydrolase
Chain: A: PDB Molecule:oligoribonuclease;
PDBTitle: structure of an oligoribonuclease (orn) from coxiella burnetii
8c3cm6A_



99.5 14 PDB header:hydrolase, apoptosis
Chain: A: PDB Molecule:cell death-related nuclease 4;
PDBTitle: crystal structure of cell-death related nuclease 4 (crn-4)2 bound with er
9d1w0ha_



99.5 15 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
10c1zbhA_



99.5 16 PDB header:hydrolase/rna
Chain: A: PDB Molecule:3'-5' exonuclease eri1;
PDBTitle: 3'-end specific recognition of histone mrna stem-loop by 3'-2 exonuclease
11c2xriA_



99.4 17 PDB header:hydrolase
Chain: A: PDB Molecule:eri1 exoribonuclease 3;
PDBTitle: crystal structure of human eri1 exoribonuclease 3
12d1y97a1



99.4 15 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
13d2f96a1



99.3 19 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
14c3u6fA_



99.3 20 PDB header:hydrolase/dna
Chain: A: PDB Molecule:three prime repair exonuclease 1;
PDBTitle: mouse trex1 d200n mutant
15d3b6oa1



99.3 20 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
16c1zbuB_



99.3 16 PDB header:hydrolase
Chain: B: PDB Molecule:3'-5' exonuclease eri1;
PDBTitle: crystal structure of full-length 3'-exonuclease
17d2qxfa1



99.2 15 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
18c2is3B_



98.6 16 PDB header:hydrolase
Chain: B: PDB Molecule:ribonuclease t;
PDBTitle: crystal structure of escherichia coli rnase t
19d1kfsa1



98.3 18 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
20c2e6mA_



98.3 16 PDB header:hydrolase
Chain: A: PDB Molecule:werner syndrome atp-dependent helicase homolog;
PDBTitle: structure of mouse werner exonuclease domain
21c1yt3A_



not modelled 98.2 19 PDB header:hydrolase,translation
Chain: A: PDB Molecule:ribonuclease d;
PDBTitle: crystal structure of escherichia coli rnase d, an2 exoribonuclease involved in structured rna processing
22c2kzzA_



not modelled 98.2 18 PDB header:transferase/dna
Chain: A: PDB Molecule:protein (dna polymerase i);
PDBTitle: klenow fragment with normal substrate and zinc only
23d1yt3a3



not modelled 97.9 20 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
24c2xcmE_



97.5 21 PDB header:chaperone/protein binding
Chain: E: PDB Molecule:rar1;
PDBTitle: complex of hsp90 n-terminal, sgt1 cs and rar1 chord2 domain
25d2hbka2



not modelled 97.5 21 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
26c3cymA_



not modelled 97.5 18 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein bad_0989;
PDBTitle: crystal structure of protein bad_0989 from bifidobacterium2 adolescentis
27c2hbkA_



not modelled 97.4 22 PDB header:hydrolase, gene regulation
Chain: A: PDB Molecule:exosome complex exonuclease rrp6;
PDBTitle: structure of the yeast nuclear exosome component, rrp6p,2 reveals an interplay between the active site and the hrdc3 domain; protein in complex with mn
28d1uoca_



not modelled 97.3 19 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:CAF1-like ribonuclease
29c2yrtA_



97.2 27 PDB header:transcription
Chain: A: PDB Molecule:chord containing protein-1;
PDBTitle: solution structure of the chord domain of human chord-2 containing protein 1
30c1njzA_



not modelled 97.1 16 PDB header:transferase/dna
Chain: A: PDB Molecule:dna polymerase i;
PDBTitle: cytosine-thymine mismatch at the polymerase active site
31c3sahA_



not modelled 97.1 21 PDB header:hydrolase
Chain: A: PDB Molecule:exosome component 10;
PDBTitle: crystal structure of the human rrp6 catalytic domain with y436a2 mutation in the catalytic site
32d1vk0a_



not modelled 97.1 20 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
33d2d5ra1



not modelled 97.0 16 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:CAF1-like ribonuclease
34c2p51A_



not modelled 97.0 17 PDB header:hydrolase, gene regulation
Chain: A: PDB Molecule:spcc18.06c protein;
PDBTitle: crystal structure of the s. pombe pop2p deadenylation2 subunit
35d2hhva1



not modelled 96.8 16 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
36d1wn7a1



not modelled 96.4 17 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
37d1tgoa1



not modelled 95.9 15 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
38c2k0nA_



95.3 11 PDB header:transcription
Chain: A: PDB Molecule:mediator of rna polymerase ii transcription
PDBTitle: solution structure of yeast gal11p kix domain
39d1qhta1



not modelled 95.0 17 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
40c4ktqA_



not modelled 94.8 17 PDB header:transferase/dna
Chain: A: PDB Molecule:protein (large fragment of dna polymerase i);
PDBTitle: binary complex of the large fragment of dna polymerase i2 from t. aquaticus bound to a primer/template dna
41d1d5aa1



not modelled 94.5 16 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
42c1q8iA_



not modelled 94.3 19 PDB header:transferase
Chain: A: PDB Molecule:dna polymerase ii;
PDBTitle: crystal structure of escherichia coli dna polymerase ii
43d1q8ia1



not modelled 94.0 20 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
44c2dtuA_



not modelled 93.7 19 PDB header:transferase/dna
Chain: A: PDB Molecule:dna polymerase;
PDBTitle: crystal structure of the beta hairpin loop deletion variant2 of rb69 gp43 in complex with dna containing an abasic site3 analog
45c1s5jA_



not modelled 93.1 18 PDB header:transferase
Chain: A: PDB Molecule:dna polymerase i;
PDBTitle: insight in dna replication: the crystal structure of dna2 polymerase b1 from the archaeon sulfolobus solfataricus
46d1ih7a1



not modelled 92.3 17 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
47c3iayA_



not modelled 91.4 21 PDB header:transferase/dna
Chain: A: PDB Molecule:dna polymerase delta catalytic subunit;
PDBTitle: ternary complex of dna polymerase delta
48c1tk0A_



not modelled 91.0 15 PDB header:transferase/electron transport/dna
Chain: A: PDB Molecule:dna polymerase;
PDBTitle: t7 dna polymerase ternary complex with 8 oxo guanosine and2 ddctp at the insertion site
49c2a1sC_



not modelled 89.5 17 PDB header:hydrolase
Chain: C: PDB Molecule:poly(a)-specific ribonuclease parn;
PDBTitle: crystal structure of native parn nuclease domain
50d1s5ja1



not modelled 89.3 16 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
51c1d5aA_



not modelled 88.9 19 PDB header:transferase
Chain: A: PDB Molecule:protein (dna polymerase);
PDBTitle: crystal structure of an archaebacterial dna polymerase2 d.tok. deposition of second native structure at 2.43 angstrom
52c3d45B_



not modelled 86.4 15 PDB header:hydrolase
Chain: B: PDB Molecule:poly(a)-specific ribonuclease parn;
PDBTitle: crystal structure of mouse parn in complex with m7gpppg
53d1noya_



not modelled 86.3 14 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
54c2ys2A_



not modelled 84.9 25 PDB header:transferase
Chain: A: PDB Molecule:cytoplasmic tyrosine-protein kinase bmx;
PDBTitle: solution structure of the btk motif of human cytoplasmic2 tyrosine-protein kinase bmx
55d1x9ma1



not modelled 84.4 18 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:DnaQ-like 3'-5' exonuclease
56c2e6iA_



84.2 15 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase itk/tsk;
PDBTitle: solution structure of the btk motif of tyrosine-protein2 kinase itk from human
57d1btka_



not modelled 82.5 34 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Pleckstrin-homology domain (PH domain)
58c2vwkA_



not modelled 82.0 18 PDB header:dna replication
Chain: A: PDB Molecule:dna polymerase;
PDBTitle: uracil recognition in archaeal dna polymerases captured by2 x-ray crystallography. v93q polymerase variant
59c2gv9B_



not modelled 81.9 13 PDB header:transferase
Chain: B: PDB Molecule:dna polymerase;
PDBTitle: crystal structure of the herpes simplex virus type 1 dna polymerase
60c1i6vD_



78.7 31 PDB header:transcription
Chain: D: PDB Molecule:dna-directed rna polymerase;
PDBTitle: thermus aquaticus core rna polymerase-rifampicin complex
61d1i6vd_



78.7 31 Fold:beta and beta-prime subunits of DNA dependent RNA-polymerase
Superfamily:beta and beta-prime subunits of DNA dependent RNA-polymerase
Family:RNA-polymerase beta-prime
62d1ynjd1



76.4 29 Fold:beta and beta-prime subunits of DNA dependent RNA-polymerase
Superfamily:beta and beta-prime subunits of DNA dependent RNA-polymerase
Family:RNA-polymerase beta-prime
63c1cmwA_



not modelled 74.5 18 PDB header:transferase
Chain: A: PDB Molecule:protein (dna polymerase i);
PDBTitle: crystal structure of taq dna-polymerase shows a new orientation for2 the structure-specific nuclease domain
64c2gutA_



not modelled 74.3 12 PDB header:transcription
Chain: A: PDB Molecule:arc/mediator, positive cofactor 2 glutamine/q-
PDBTitle: solution structure of the trans-activation domain of the2 human co-activator arc105
65c3bdvB_



not modelled 60.2 35 PDB header:hydrolase
Chain: B: PDB Molecule:uncharacterized protein duf1234;
PDBTitle: crystal structure of a putative yden-like hydrolase (eca3091) from2 pectobacterium atrosepticum scri1043 at 1.66 a resolution
66d3bzka5



not modelled 56.7 27 Fold:Ribonuclease H-like motif
Superfamily:Ribonuclease H-like
Family:Tex RuvX-like domain-like
67c3ho6B_



not modelled 53.1 16 PDB header:toxin
Chain: B: PDB Molecule:toxin a;
PDBTitle: structure-function analysis of inositol hexakisphosphate-2 induced autoprocessing in clostridium difficile toxin a
68c3qqcA_



not modelled 51.2 18 PDB header:transcription
Chain: A: PDB Molecule:dna-directed rna polymerase subunit b, dna-directed rna
PDBTitle: crystal structure of archaeal spt4/5 bound to the rnap clamp domain
69c3zyqA_



not modelled 48.2 14 PDB header:signaling
Chain: A: PDB Molecule:hepatocyte growth factor-regulated tyrosine kinase
PDBTitle: crystal structure of the tandem vhs and fyve domains of hepatocyte2 growth factor-regulated tyrosine kinase substrate (hgs-hrs) at 1.483 a resolution
70d1wiga2



not modelled 45.8 21 Fold:Glucocorticoid receptor-like (DNA-binding domain)
Superfamily:Glucocorticoid receptor-like (DNA-binding domain)
Family:LIM domain
71c1dvpA_



not modelled 42.4 18 PDB header:transferase
Chain: A: PDB Molecule:hepatocyte growth factor-regulated tyrosine
PDBTitle: crystal structure of the vhs and fyve tandem domains of hrs,2 a protein involved in membrane trafficking and signal3 transduction
72c1pqvS_



not modelled 40.0 15 PDB header:transferase/transcription
Chain: S: PDB Molecule:transcription elongation factor s-ii;
PDBTitle: rna polymerase ii-tfiis complex
73c1y1yS_



not modelled 40.0 15 PDB header:transferase/transcription/dna-rna hybrid
Chain: S: PDB Molecule:transcription elongation factor s-ii;
PDBTitle: rna polymerase ii-tfiis-dna/rna complex
74d1wfla_



not modelled 38.8 26 Fold:AN1-like Zinc finger
Superfamily:AN1-like Zinc finger
Family:AN1-like Zinc finger
75c2kvfA_



not modelled 37.8 30 PDB header:transcription
Chain: A: PDB Molecule:zinc finger and btb domain-containing protein 32;
PDBTitle: structure of the three-cys2his2 domain of mouse testis zinc2 finger protein
76d1sb0a_



not modelled 34.5 11 Fold:Kix domain of CBP (creb binding protein)
Superfamily:Kix domain of CBP (creb binding protein)
Family:Kix domain of CBP (creb binding protein)
77c3hz6A_



not modelled 33.1 16 PDB header:transferase
Chain: A: PDB Molecule:xylulokinase;
PDBTitle: crystal structure of xylulokinase from chromobacterium violaceum
78c2e72A_



not modelled 32.8 31 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:pogo transposable element with znf domain;
PDBTitle: solution structure of the zinc finger domain of human2 kiaa0461
79d1ibia1



not modelled 32.4 25 Fold:Glucocorticoid receptor-like (DNA-binding domain)
Superfamily:Glucocorticoid receptor-like (DNA-binding domain)
Family:LIM domain
80c2cftA_



not modelled 32.2 15 PDB header:phosphatase
Chain: A: PDB Molecule:pyridoxal phosphate phosphatase;
PDBTitle: crystal structure of human pyridoxal 5'-phosphate2 phosphatase with its substrate
81d1g47a1



not modelled 31.5 32 Fold:Glucocorticoid receptor-like (DNA-binding domain)
Superfamily:Glucocorticoid receptor-like (DNA-binding domain)
Family:LIM domain
82d1gpla2



not modelled 31.4 34 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Pancreatic lipase, N-terminal domain
83d1x6ha1



not modelled 30.2 44 Fold:beta-beta-alpha zinc fingers
Superfamily:beta-beta-alpha zinc fingers
Family:Classic zinc finger, C2H2
84c3psfA_



not modelled 29.8 18 PDB header:transcription
Chain: A: PDB Molecule:transcription elongation factor spt6;
PDBTitle: crystal structure of the spt6 core domain from saccharomyces2 cerevisiae, form spt6(236-1259)
85c2elrA_



not modelled 28.7 19 PDB header:transcription
Chain: A: PDB Molecule:zinc finger protein 406;
PDBTitle: solution structure of the 15th c2h2 zinc finger of human2 zinc finger protein 406
86c2aklA_



not modelled 27.5 28 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:phna-like protein pa0128;
PDBTitle: solution structure for phn-a like protein pa0128 from2 pseudomonas aeruginosa
87c2jr7A_



not modelled 27.1 16 PDB header:metal binding protein
Chain: A: PDB Molecule:dph3 homolog;
PDBTitle: solution structure of human desr1
88d2k4xa1



not modelled 27.1 21 Fold:Rubredoxin-like
Superfamily:Zn-binding ribosomal proteins
Family:Ribosomal protein S27a
89c2lo3A_



not modelled 26.2 23 PDB header:transcription
Chain: A: PDB Molecule:saga-associated factor 73;
PDBTitle: solution structure of sgf73(59-102) zinc finger domain
90c2zkr4_



not modelled 25.8 23 PDB header:ribosomal protein/rna
Chain: 4: PDB Molecule:60s ribosomal protein l44e;
PDBTitle: structure of a mammalian ribosomal 60s subunit within an2 80s complex obtained by docking homology models of the rna3 and proteins into an 8.7 a cryo-em map
91c2f9yB_



not modelled 25.7 16 PDB header:ligase
Chain: B: PDB Molecule:acetyl-coenzyme a carboxylase carboxyl transferase subunit
PDBTitle: the crystal structure of the carboxyltransferase subunit of acc from2 escherichia coli
92d2f9yb1



not modelled 25.7 16 Fold:ClpP/crotonase
Superfamily:ClpP/crotonase
Family:Biotin dependent carboxylase carboxyltransferase domain
93d1ubdc2



not modelled 24.2 40 Fold:beta-beta-alpha zinc fingers
Superfamily:beta-beta-alpha zinc fingers
Family:Classic zinc finger, C2H2
94d1b8ta3



not modelled 23.8 17 Fold:Glucocorticoid receptor-like (DNA-binding domain)
Superfamily:Glucocorticoid receptor-like (DNA-binding domain)
Family:LIM domain
95c3lp5A_



not modelled 23.2 12 PDB header:hydrolase
Chain: A: PDB Molecule:putative cell surface hydrolase;
PDBTitle: the crystal structure of the putative cell surface hydrolase from2 lactobacillus plantarum wcfs1
96d1pjaa_



not modelled 23.1 8 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Thioesterases
97c1pjaA_



not modelled 23.1 8 PDB header:hydrolase
Chain: A: PDB Molecule:palmitoyl-protein thioesterase 2 precursor;
PDBTitle: the crystal structure of palmitoyl protein thioesterase-2 reveals the2 basis for divergent substrate specificities of the two lysosomal3 thioesterases (ppt1 and ppt2)
98d2b4jc1



not modelled 22.9 15 Fold:N-cbl like
Superfamily:HIV integrase-binding domain
Family:HIV integrase-binding domain
99d1jvna1



not modelled 22.8 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
100d1uxoa_



not modelled 22.5 22 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:YdeN-like
101c2gb5B_



not modelled 22.4 23 PDB header:hydrolase
Chain: B: PDB Molecule:nadh pyrophosphatase;
PDBTitle: crystal structure of nadh pyrophosphatase (ec 3.6.1.22) (1790429) from2 escherichia coli k12 at 2.30 a resolution
102d2b0la1



not modelled 22.2 25 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:CodY HTH domain
103c1t39A_



not modelled 21.9 22 PDB header:transferase/dna
Chain: A: PDB Molecule:methylated-dna--protein-cysteine
PDBTitle: human o6-alkylguanine-dna alkyltransferase covalently2 crosslinked to dna
104c2co8A_



not modelled 21.6 23 PDB header:metal binding protein
Chain: A: PDB Molecule:nedd9 interacting protein with calponin homology
PDBTitle: solution structures of the lim domain of human nedd92 interacting protein with calponin homology and lim domains
105d1ywsa1



not modelled 21.3 16 Fold:Rubredoxin-like
Superfamily:CSL zinc finger
Family:CSL zinc finger
106c2zyiB_



not modelled 21.2 28 PDB header:hydrolase
Chain: B: PDB Molecule:lipase, putative;
PDBTitle: a. fulgidus lipase with fatty acid fragment and calcium
107d1xpaa2



not modelled 20.8 44 Fold:Glucocorticoid receptor-like (DNA-binding domain)
Superfamily:Glucocorticoid receptor-like (DNA-binding domain)
Family:DNA repair factor XPA DNA- and RPA-binding domain, N-terminal subdomain
108d1ydfa1



not modelled 20.6 11 Fold:HAD-like
Superfamily:HAD-like
Family:NagD-like
109d2yt9a1



not modelled 20.4 33 Fold:beta-beta-alpha zinc fingers
Superfamily:beta-beta-alpha zinc fingers
Family:Classic zinc finger, C2H2
110c2k42A_



not modelled 20.2 21 PDB header:signaling protein
Chain: A: PDB Molecule:wiskott-aldrich syndrome protein;
PDBTitle: solution structure of the gtpase binding domain of wasp in2 complex with espfu, an ehec effector
111c1b8tA_



not modelled 20.1 16 PDB header:contractile
Chain: A: PDB Molecule:protein (crp1);
PDBTitle: solution structure of the chicken crp1
112d1wgea1



not modelled 20.1 16 Fold:Rubredoxin-like
Superfamily:CSL zinc finger
Family:CSL zinc finger

Binding site prediction 

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