PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c1dvpA_

Fold library id	PDB Header	Molecule	Title
c1dvpA_	PDB header: transferase	Chain: A: PDB Molecule: hepatocyte growth factor-regulated tyrosine	PDBTitle: crystal structure of the vhs and fyve tandem domains of hrs,2 a protein involved in membrane trafficking and signal3 transduction

Links to external resources
Added to library: Tue Mar 16 13:09:48 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence M F R S S F C K N L E N A T S H L R L E P D W P S I L L I C D E I N Q K D V T P K N A F A A I K K K M N S P N P H S S C Y S L L V L E S I V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T T
S S
T T S S
T
S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence K N C G A P V H E E V F T K E N C E M F S S F L E S T P H E N V R Q K M L E L V Q T W A Y A F R S S D K Y Q A I K D T M T I L K A K G H T F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S S
S
T T T
S S
T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence P E L R E M F T A D T A P N W A D G R V C H R C R V E F T F T N R K H H C R N C G Q V F C G Q C T A K Q C P L P K Y G I E K E V R V C D G C

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S B
T T T
B
S S S
T T T
S T T S
G G G T

. . . . . . .

Sequence F A A L Q R G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	M	F	R	S	S	F	C	K	N	L	E	N	A	T	S	H	L	R	L	E	P	D	W	P	S	I	L	L	I	C	D	E	I	N	Q	K	D	V	T	P	K	N	A	F	A	A	I	K	K	K	M	N	S	P	N	P	H	S	S	C	Y	S	L	L	V	L	E	S	I	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S												T	T		S	S															T	T	S	S														T		S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	K	N	C	G	A	P	V	H	E	E	V	F	T	K	E	N	C	E	M	F	S	S	F	L	E	S	T	P	H	E	N	V	R	Q	K	M	L	E	L	V	Q	T	W	A	Y	A	F	R	S	S	D	K	Y	Q	A	I	K	D	T	M	T	I	L	K	A	K	G	H	T	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S									S	S															S																			T	T	T		S	S														T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	P	E	L	R	E	M	F	T	A	D	T	A	P	N	W	A	D	G	R	V	C	H	R	C	R	V	E	F	T	F	T	N	R	K	H	H	C	R	N	C	G	Q	V	F	C	G	Q	C	T	A	K	Q	C	P	L	P	K	Y	G	I	E	K	E	V	R	V	C	D	G	C
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										S									S	B		T	T	T			B			S	S	S						T	T	T						S	T	T	S							G	G	G	T
	.	.	.	.	.	.	.
Sequence	F	A	A	L	Q	R	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)