Phyre 2 Results for P47768

Email	l.a.kelley@imperial.ac.uk
Description	P47768
Date	Tue Jul 17 17:05:10 BST 2012
Unique Job ID	a484637e4f5d2acd

Summary

Top model

Image coloured by rainbow N → C terminus

Model (left) based on template d1smyc_

Top template information

Fold:beta and beta-prime subunits of DNA dependent RNA-polymerase
Superfamily:beta and beta-prime subunits of DNA dependent RNA-polymerase
Family:RNA-polymerase beta

Confidence and coverage

Confidence:

100.0%

Coverage:

89%

1048 residues ( 89% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M A G Q V V Q Y G R H R K R R N Y A R I S E V L E L P N L I E I Q T K S Y E W F L R E G L I E M F R D I S P I E D F T G

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ?
?
? ?
?
?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence N L S L E F V D Y R L G E P K Y D L E E S K N R D A T Y A A P L R V K V R L I I K E T G E V K E Q E V F M G D F P L M T

Secondary structure

SS confidence

Disorder
?
?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence D T G T F V I N G A E R V I V S Q L V R S P S V Y F N E K I D K N G R E N Y D A T I I P N R G A W L E Y E T D A K D V V

Secondary structure

SS confidence

Disorder
?
?

Disorder confidence

. . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240

Sequence Y V R I D R T R K L P L T V L L R A L G F S S D Q E I V D L L G D N E Y L R N T L E K D G T E N T E Q A L L E I Y E R L

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280 . . . . . . . . . 290 . . . . . . . . . 300

Sequence R P G E P P T V E N A K S L L Y S R F F D P K R Y D L A S V G R Y K T N K K L H L K H R L F N Q K L A E P I V N T E T G

Secondary structure

SS confidence

Disorder
? ?
?
?
?
? ?

Disorder confidence

. . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350 . . . . . . . . . 360

Sequence E I V V E E G T V L D R R K I D E I M D V L E S N A N S E V F E L H G S V I D E P V E I Q S I K V Y V P N D D E G R T T

Secondary structure

SS confidence

Disorder
?
?
?
? ?

Disorder confidence

. . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence T V I G N A F P D S E V K C I T P A D I I A S M S Y F F N L L S G I G Y T D D I D H L G N R R L R S V G E L L Q N Q F R

Secondary structure

SS confidence

Disorder
?
?
? ?
? ?
? ?

Disorder confidence

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480

Sequence I G L S R M E R V V R E R M S I Q D T E S I T P Q Q L I N I R P V I A S I K E F F G S S Q L S Q F M D Q A N P L A E L T

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 490 . . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540

Sequence H K R R L S A L G P G G L T R E R A Q M E V R D V H Y S H Y G R M C P I E T P E G P N I G L I N S L S S Y A R V N E F G

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
?
? ? ?

Disorder confidence

. . . . . . . . . 550 . . . . . . . . . 560 . . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600

Sequence F I E T P Y R K V D L D T H A I T D Q I D Y L T A D E E D S Y V V A Q A N S K L D E N G R F M D D E V V C R F R G N N T

Secondary structure

SS confidence

Disorder ? ?
? ? ?
?
?

Disorder confidence

. . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630 . . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660

Sequence V M A K E K M D Y M D V S P K Q V V S A A T A C I P F L E N D D S N R A L M G A N M Q R Q A V P L M N P E A P F V G T G

Secondary structure

SS confidence

Disorder ?

Disorder confidence

. . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700 . . . . . . . . . 710 . . . . . . . . . 720

Sequence M E H V A A R D S G A A I T A K H R G R V E H V E S N E I L V R R L V E E N G V E H E G E L D R Y P L A K F K R S N S G

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ?
?
?

Disorder confidence

. . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770 . . . . . . . . . 780

Sequence T C Y N Q R P I V A V G D V V E Y N E I L A D G P S M E L G E M A L G R N V V V G F M T W D G Y N Y E D A V I M S E R L

Secondary structure

SS confidence

Disorder
? ?
?

Disorder confidence

. . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence V K D D V Y T S I H I E E Y E S E A R D T K L G P E E I T R D I P N V S E S A L K N L D D R G I V Y I G A E V K D G D I

Secondary structure

SS confidence

Disorder
?
? ? ? ? ? ? ? ?
?
? ?

Disorder confidence

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900

Sequence L V G K V T P K G V T E L T A E E R L L H A I F G E K A R E V R D T S L R V P H G A G G I V L D V K V F N R E E G D D T

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ?
? ?
? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 910 . . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960

Sequence L S P G V N Q L V R V Y I V Q K R K I H V G D K M C G R H G N K G V I S K I V P E E D M P Y L P D G R P I D I M L N P L

Secondary structure

SS confidence

Disorder ? ?
?

Disorder confidence

. . . . . . . . . 970 . . . . . . . . . 980 . . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020

Sequence G V P S R M N I G Q V L E L H L G M A A K N L G I H V A S P V F D G A N D D D V W S T I E E A G M A R D G K T V L Y D G

Secondary structure

SS confidence

Disorder
?
?

Disorder confidence

. . . . . . . . . 1030 . . . . . . . . . 1040 . . . . . . . . . 1050 . . . . . . . . . 1060 . . . . . . . . . 1070 . . . . . . . . . 1080

Sequence R T G E P F D N R I S V G V M Y M L K L A H M V D D K L H A R S T G P Y S L V T Q Q P L G G K A Q F G G Q R F G E M E V

Secondary structure

SS confidence

Disorder
? ?
? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 1090 . . . . . . . . . 1100 . . . . . . . . . 1110 . . . . . . . . . 1120 . . . . . . . . . 1130 . . . . . . . . . 1140

Sequence W A L E A Y G A A Y T L Q E I L T Y K S D D T V G R V K T Y E A I V K G E N I S R P S V P E S F R V L M K E L Q S L G L

Secondary structure

SS confidence

Disorder
? ?

Disorder confidence

. . . . . . . . . 1150 . . . . . . . . . 1160 . . . . . . . . . 1170 . . . . . . . . . 1180 . . .

Sequence D V K V M D E Q D N E I E M T D V D D D D V V E R K V D L Q Q N D A P E T Q K E V T D

Secondary structure

SS confidence

Disorder
?
?
? ?
? ? ? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered

Alpha helix

Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 1smy chain C

Region: 15 - 1156
Aligned: 1048
Modelled: 1060
Confidence: 100.0%
Identity: 54%
Fold: beta and beta-prime subunits of DNA dependent RNA-polymerase
Superfamily: beta and beta-prime subunits of DNA dependent RNA-polymerase
Family: RNA-polymerase beta

Phyre2

PDB 3iyd chain C

Region: 12 - 1147
Aligned: 1036
Modelled: 1036
Confidence: 100.0%
Identity: 58%
PDB header:transcription/dna
Chain: C: PDB Molecule:dna-directed rna polymerase subunit beta;
PDBTitle: three-dimensional em structure of an intact activator-dependent2 transcription initiation complex

Phyre2

PDB 1ynj chain C domain 1

Region: 15 - 1156
Aligned: 1046
Modelled: 1048
Confidence: 100.0%
Identity: 55%
Fold: beta and beta-prime subunits of DNA dependent RNA-polymerase
Superfamily: beta and beta-prime subunits of DNA dependent RNA-polymerase
Family: RNA-polymerase beta

Phyre2

PDB 2pmz chain B

Region: 12 - 1148
Aligned: 998
Modelled: 1011
Confidence: 100.0%
Identity: 29%
PDB header:translation, transferase
Chain: B: PDB Molecule:dna-directed rna polymerase subunit b;
PDBTitle: archaeal rna polymerase from sulfolobus solfataricus

Phyre2

PDB 3h0g chain N

Region: 15 - 1150
Aligned: 998
Modelled: 985
Confidence: 100.0%
Identity: 26%
PDB header:transcription
Chain: N: PDB Molecule:dna-directed rna polymerase ii subunit rpb2;
PDBTitle: rna polymerase ii from schizosaccharomyces pombe

Phyre2

PDB 1twf chain B

Region: 14 - 1151
Aligned: 968
Modelled: 1010
Confidence: 100.0%
Identity: 25%
Fold: beta and beta-prime subunits of DNA dependent RNA-polymerase
Superfamily: beta and beta-prime subunits of DNA dependent RNA-polymerase
Family: RNA-polymerase beta

Phyre2

PDB 3mlq chain D

Region: 26 - 468
Aligned: 173
Modelled: 174
Confidence: 100.0%
Identity: 62%
PDB header:transferase/transcription
Chain: D: PDB Molecule:dna-directed rna polymerase subunit beta;
PDBTitle: crystal structure of the thermus thermophilus transcription-repair2 coupling factor rna polymerase interacting domain with the thermus3 aquaticus rna polymerase beta1 domain

Phyre2

PDB 3mlq chain B

Region: 29 - 467
Aligned: 169
Modelled: 170
Confidence: 100.0%
Identity: 63%
PDB header:transferase/transcription
Chain: B: PDB Molecule:dna-directed rna polymerase subunit beta;
PDBTitle: crystal structure of the thermus thermophilus transcription-repair2 coupling factor rna polymerase interacting domain with the thermus3 aquaticus rna polymerase beta1 domain

Phyre2

PDB 3tbi chain B

Region: 789 - 986
Aligned: 196
Modelled: 198
Confidence: 99.9%
Identity: 44%
PDB header:transcription
Chain: B: PDB Molecule:dna-directed rna polymerase subunit beta;
PDBTitle: crystal structure of t4 gp33 bound to e. coli rnap beta-flap domain

Phyre2

PDB 3lti chain A

Region: 141 - 398
Aligned: 161
Modelled: 172
Confidence: 99.9%
Identity: 60%
PDB header:transferase
Chain: A: PDB Molecule:dna-directed rna polymerase subunit beta;
PDBTitle: crystal structure of the escherichia coli rna polymerase beta subunit2 beta2-betai4 domains

Phyre2

PDB 3qqc chain A

Region: 1077 - 1148
Aligned: 63
Modelled: 72
Confidence: 99.2%
Identity: 24%
PDB header:transcription
Chain: A: PDB Molecule:dna-directed rna polymerase subunit b, dna-directed rna
PDBTitle: crystal structure of archaeal spt4/5 bound to the rnap clamp domain

Phyre2

PDB 1r46 chain A domain 1

Region: 938 - 962
Aligned: 25
Modelled: 25
Confidence: 47.4%
Identity: 16%
Fold: Glycosyl hydrolase domain
Superfamily: Glycosyl hydrolase domain
Family: alpha-Amylases, C-terminal beta-sheet domain

Phyre2

PDB 1zq1 chain C domain 1

Region: 1131 - 1142
Aligned: 12
Modelled: 12
Confidence: 36.0%
Identity: 42%
Fold: GatB/YqeY motif
Superfamily: GatB/YqeY motif
Family: GatB/GatE C-terminal domain-like

Phyre2

PDB 1n26 chain A domain 2

Region: 927 - 962
Aligned: 36
Modelled: 36
Confidence: 31.4%
Identity: 19%
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Fibronectin type III
Family: Fibronectin type III

Phyre2

PDB 1d02 chain A

Region: 940 - 957
Aligned: 18
Modelled: 18
Confidence: 30.3%
Identity: 17%
Fold: Restriction endonuclease-like
Superfamily: Restriction endonuclease-like
Family: Restriction endonuclease MunI

Phyre2

PDB 1nbw chain A domain 1

Region: 748 - 785
Aligned: 37
Modelled: 38
Confidence: 27.4%
Identity: 14%
Fold: The "swivelling" beta/beta/alpha domain
Superfamily: Swiveling domain of dehydratase reactivase alpha subunit
Family: Swiveling domain of dehydratase reactivase alpha subunit

Phyre2

PDB 1uj4 chain A domain 2

Region: 1124 - 1152
Aligned: 29
Modelled: 29
Confidence: 27.3%
Identity: 24%
Fold: Ferredoxin-like
Superfamily: D-ribose-5-phosphate isomerase (RpiA), lid domain
Family: D-ribose-5-phosphate isomerase (RpiA), lid domain

Phyre2

PDB 2gti chain A

Region: 1021 - 1084
Aligned: 63
Modelled: 62
Confidence: 26.9%
Identity: 16%
PDB header:viral protein
Chain: A: PDB Molecule:replicase polyprotein 1ab;
PDBTitle: mutation of mhv coronavirus non-structural protein nsp15 (f307l)

Phyre2

PDB 1gm5 chain A domain 4

Region: 926 - 945
Aligned: 20
Modelled: 20
Confidence: 23.9%
Identity: 20%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: Tandem AAA-ATPase domain

Phyre2

PDB 1uj6 chain A

Region: 1087 - 1152
Aligned: 65
Modelled: 65
Confidence: 23.2%
Identity: 15%
PDB header:isomerase
Chain: A: PDB Molecule:ribose 5-phosphate isomerase;
PDBTitle: crystal structure of thermus thermophilus ribose-5-phosphate isomerase2 complexed with arabinose-5-phosphate

Phyre2

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence	M	A	G	Q	V	V	Q	Y	G	R	H	R	K	R	R	N	Y	A	R	I	S	E	V	L	E	L	P	N	L	I	E	I	Q	T	K	S	Y	E	W	F	L	R	E	G	L	I	E	M	F	R	D	I	S	P	I	E	D	F	T	G
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?	?	?			?		?	?																																										?		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence	N	L	S	L	E	F	V	D	Y	R	L	G	E	P	K	Y	D	L	E	E	S	K	N	R	D	A	T	Y	A	A	P	L	R	V	K	V	R	L	I	I	K	E	T	G	E	V	K	E	Q	E	V	F	M	G	D	F	P	L	M	T
Secondary structure
SS confidence
Disorder															?																												?
Disorder confidence

	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence	D	T	G	T	F	V	I	N	G	A	E	R	V	I	V	S	Q	L	V	R	S	P	S	V	Y	F	N	E	K	I	D	K	N	G	R	E	N	Y	D	A	T	I	I	P	N	R	G	A	W	L	E	Y	E	T	D	A	K	D	V	V
Secondary structure
SS confidence
Disorder																?														?
Disorder confidence

	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence	Y	V	R	I	D	R	T	R	K	L	P	L	T	V	L	L	R	A	L	G	F	S	S	D	Q	E	I	V	D	L	L	G	D	N	E	Y	L	R	N	T	L	E	K	D	G	T	E	N	T	E	Q	A	L	L	E	I	Y	E	R	L
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence	R	P	G	E	P	P	T	V	E	N	A	K	S	L	L	Y	S	R	F	F	D	P	K	R	Y	D	L	A	S	V	G	R	Y	K	T	N	K	K	L	H	L	K	H	R	L	F	N	Q	K	L	A	E	P	I	V	N	T	E	T	G
Secondary structure
SS confidence
Disorder		?	?		?		?																											?							?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence	E	I	V	V	E	E	G	T	V	L	D	R	R	K	I	D	E	I	M	D	V	L	E	S	N	A	N	S	E	V	F	E	L	H	G	S	V	I	D	E	P	V	E	I	Q	S	I	K	V	Y	V	P	N	D	D	E	G	R	T	T
Secondary structure
SS confidence
Disorder																												?					?				?																		?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	T	V	I	G	N	A	F	P	D	S	E	V	K	C	I	T	P	A	D	I	I	A	S	M	S	Y	F	F	N	L	L	S	G	I	G	Y	T	D	D	I	D	H	L	G	N	R	R	L	R	S	V	G	E	L	L	Q	N	Q	F	R
Secondary structure
SS confidence
Disorder						?				?																							?	?		?	?		?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence	I	G	L	S	R	M	E	R	V	V	R	E	R	M	S	I	Q	D	T	E	S	I	T	P	Q	Q	L	I	N	I	R	P	V	I	A	S	I	K	E	F	F	G	S	S	Q	L	S	Q	F	M	D	Q	A	N	P	L	A	E	L	T
Secondary structure
SS confidence
Disorder														?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence	H	K	R	R	L	S	A	L	G	P	G	G	L	T	R	E	R	A	Q	M	E	V	R	D	V	H	Y	S	H	Y	G	R	M	C	P	I	E	T	P	E	G	P	N	I	G	L	I	N	S	L	S	S	Y	A	R	V	N	E	F	G
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																														?				?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence	F	I	E	T	P	Y	R	K	V	D	L	D	T	H	A	I	T	D	Q	I	D	Y	L	T	A	D	E	E	D	S	Y	V	V	A	Q	A	N	S	K	L	D	E	N	G	R	F	M	D	D	E	V	V	C	R	F	R	G	N	N	T
Secondary structure
SS confidence
Disorder	?	?									?	?	?			?																																											?
Disorder confidence

	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660
Sequence	V	M	A	K	E	K	M	D	Y	M	D	V	S	P	K	Q	V	V	S	A	A	T	A	C	I	P	F	L	E	N	D	D	S	N	R	A	L	M	G	A	N	M	Q	R	Q	A	V	P	L	M	N	P	E	A	P	F	V	G	T	G
Secondary structure
SS confidence
Disorder	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720
Sequence	M	E	H	V	A	A	R	D	S	G	A	A	I	T	A	K	H	R	G	R	V	E	H	V	E	S	N	E	I	L	V	R	R	L	V	E	E	N	G	V	E	H	E	G	E	L	D	R	Y	P	L	A	K	F	K	R	S	N	S	G
Secondary structure
SS confidence
Disorder																																				?	?	?	?	?	?	?	?								?			?
Disorder confidence

	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780
Sequence	T	C	Y	N	Q	R	P	I	V	A	V	G	D	V	V	E	Y	N	E	I	L	A	D	G	P	S	M	E	L	G	E	M	A	L	G	R	N	V	V	V	G	F	M	T	W	D	G	Y	N	Y	E	D	A	V	I	M	S	E	R	L
Secondary structure
SS confidence
Disorder												?	?															?
Disorder confidence

	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	V	K	D	D	V	Y	T	S	I	H	I	E	E	Y	E	S	E	A	R	D	T	K	L	G	P	E	E	I	T	R	D	I	P	N	V	S	E	S	A	L	K	N	L	D	D	R	G	I	V	Y	I	G	A	E	V	K	D	G	D	I
Secondary structure
SS confidence
Disorder				?																?	?	?	?	?	?	?	?		?						?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900
Sequence	L	V	G	K	V	T	P	K	G	V	T	E	L	T	A	E	E	R	L	L	H	A	I	F	G	E	K	A	R	E	V	R	D	T	S	L	R	V	P	H	G	A	G	G	I	V	L	D	V	K	V	F	N	R	E	E	G	D	D	T
Secondary structure
SS confidence
Disorder								?	?	?	?	?	?	?	?	?	?										?	?																											?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960
Sequence	L	S	P	G	V	N	Q	L	V	R	V	Y	I	V	Q	K	R	K	I	H	V	G	D	K	M	C	G	R	H	G	N	K	G	V	I	S	K	I	V	P	E	E	D	M	P	Y	L	P	D	G	R	P	I	D	I	M	L	N	P	L
Secondary structure
SS confidence
Disorder	?	?		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020
Sequence	G	V	P	S	R	M	N	I	G	Q	V	L	E	L	H	L	G	M	A	A	K	N	L	G	I	H	V	A	S	P	V	F	D	G	A	N	D	D	D	V	W	S	T	I	E	E	A	G	M	A	R	D	G	K	T	V	L	Y	D	G
Secondary structure
SS confidence
Disorder		?		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080
Sequence	R	T	G	E	P	F	D	N	R	I	S	V	G	V	M	Y	M	L	K	L	A	H	M	V	D	D	K	L	H	A	R	S	T	G	P	Y	S	L	V	T	Q	Q	P	L	G	G	K	A	Q	F	G	G	Q	R	F	G	E	M	E	V
Secondary structure
SS confidence
Disorder																																									?	?			?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140
Sequence	W	A	L	E	A	Y	G	A	A	Y	T	L	Q	E	I	L	T	Y	K	S	D	D	T	V	G	R	V	K	T	Y	E	A	I	V	K	G	E	N	I	S	R	P	S	V	P	E	S	F	R	V	L	M	K	E	L	Q	S	L	G	L
Secondary structure
SS confidence
Disorder																																						?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.	.	.	.	.	1180	.	.	.
Sequence	D	V	K	V	M	D	E	Q	D	N	E	I	E	M	T	D	V	D	D	D	D	V	V	E	R	K	V	D	L	Q	Q	N	D	A	P	E	T	Q	K	E	V	T	D
Secondary structure
SS confidence
Disorder							?		?				?	?			?	?	?	?			?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence