Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP77658
DateThu Jan 5 12:31:27 GMT 2012
Unique Job IDc3f68563378f4f9d

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1c1gA_
Top template information
PDB header:contractile protein
Chain: A: PDB Molecule:tropomyosin;
PDBTitle: crystal structure of tropomyosin at 7 angstroms resolution2 in the spermine-induced crystal form
Confidence and coverage
Confidence: 99.0% Coverage: 82%
281 residues ( 82% of your sequence) have been modelled with 99.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MAEQTSRLAIIIDSTGAKNNADNLTSSLVKMTQAGETAANSAGKVTKATEDEKNALAKLK
Secondary structure 


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Disorder  ???








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   .........70.........80.........90.........100.........110.........120
Sequence  AAIDPVGAAIDTVGRRYSELKKFFDKGLIDKEEYEFLVRKLNETTEELSGVAQAQREAEK
Secondary structure 

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   .........130.........140.........150.........160.........170.........180
Sequence  AGKLAAAQQEAQAQAFQRMLDKIDPLAAALRNLEQQHDELNAAFASGKINGSQFENYSRK
Secondary structure 
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??









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   .........190.........200.........210.........220.........230.........240
Sequence  IQETRRELTGEAQAEREAAKAHDEQVVALQRLIAQLDPVGTAFNRLVEQQKQLNEAKAKG
Secondary structure 
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   .........250.........260.........270.........280.........290.........300
Sequence  MLSPEMYEELSGKLRAMRSELEVTQSQLSKTGMSAKQTAFAMRMLPAQMTDIVVGLSTGQ
Secondary structure 


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Disorder 
??




















































?

?
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   .........310.........320.........330.........340..
Sequence  SPFMVLMQQGGHSAMQETRIASLPVTAIPAGMKIPCVTAGSA
Secondary structure 












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Disorder  ?






?
???



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??????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1c1g chain A

3D model

Region: 16 - 299
Aligned: 281
Modelled: 284
Confidence: 99.0%
Identity: 6%
PDB header:contractile protein
Chain: A: PDB Molecule:tropomyosin;
PDBTitle: crystal structure of tropomyosin at 7 angstroms resolution2 in the spermine-induced crystal form

Phyre2

PDB 2ch7 chain A

3D model

Region: 15 - 320
Aligned: 304
Modelled: 306
Confidence: 98.4%
Identity: 10%
PDB header:chemotaxis
Chain: A: PDB Molecule:methyl-accepting chemotaxis protein;
PDBTitle: crystal structure of the cytoplasmic domain of a bacterial2 chemoreceptor from thermotoga maritima

Phyre2

PDB 2oev chain A

3D model

Region: 21 - 266
Aligned: 246
Modelled: 246
Confidence: 97.6%
Identity: 7%
PDB header:protein transport
Chain: A: PDB Molecule:programmed cell death 6-interacting protein;
PDBTitle: crystal structure of alix/aip1

Phyre2

PDB 2efr chain B

3D model

Region: 21 - 176
Aligned: 153
Modelled: 153
Confidence: 97.3%
Identity: 12%
PDB header:contractile protein
Chain: B: PDB Molecule:general control protein gcn4 and tropomyosin 1 alpha chain;
PDBTitle: crystal structure of the c-terminal tropomyosin fragment with n- and2 c-terminal extensions of the leucine zipper at 1.8 angstroms3 resolution

Phyre2

PDB 2oex chain B

3D model

Region: 15 - 270
Aligned: 256
Modelled: 256
Confidence: 97.1%
Identity: 8%
PDB header:protein transport
Chain: B: PDB Molecule:programmed cell death 6-interacting protein;
PDBTitle: structure of alix/aip1 v domain

Phyre2

PDB 1cii chain A

3D model

Region: 7 - 320
Aligned: 314
Modelled: 314
Confidence: 96.9%
Identity: 12%
PDB header:transmembrane protein
Chain: A: PDB Molecule:colicin ia;
PDBTitle: colicin ia

Phyre2

PDB 3oja chain B

3D model

Region: 143 - 288
Aligned: 144
Modelled: 146
Confidence: 96.3%
Identity: 10%
PDB header:protein binding
Chain: B: PDB Molecule:anopheles plasmodium-responsive leucine-rich repeat protein
PDBTitle: crystal structure of lrim1/apl1c complex

Phyre2

PDB 1yvl chain B

3D model

Region: 3 - 270
Aligned: 266
Modelled: 268
Confidence: 95.3%
Identity: 9%
PDB header:signaling protein
Chain: B: PDB Molecule:signal transducer and activator of transcription
PDBTitle: structure of unphosphorylated stat1

Phyre2

PDB 2d3e chain D

3D model

Region: 20 - 150
Aligned: 128
Modelled: 131
Confidence: 95.3%
Identity: 13%
PDB header:contractile protein
Chain: D: PDB Molecule:general control protein gcn4 and tropomyosin 1
PDBTitle: crystal structure of the c-terminal fragment of rabbit2 skeletal alpha-tropomyosin

Phyre2

PDB 3u59 chain C

3D model

Region: 224 - 320
Aligned: 97
Modelled: 97
Confidence: 94.9%
Identity: 6%
PDB header:contractile protein
Chain: C: PDB Molecule:tropomyosin beta chain;
PDBTitle: n-terminal 98-aa fragment of smooth muscle tropomyosin beta

Phyre2

PDB 2fxm chain B

3D model

Region: 217 - 322
Aligned: 106
Modelled: 106
Confidence: 94.6%
Identity: 8%
PDB header:contractile protein
Chain: B: PDB Molecule:myosin heavy chain, cardiac muscle beta isoform;
PDBTitle: structure of the human beta-myosin s2 fragment

Phyre2

PDB 2b9c chain A

3D model

Region: 17 - 150
Aligned: 131
Modelled: 134
Confidence: 94.5%
Identity: 9%
PDB header:contractile protein
Chain: A: PDB Molecule:striated-muscle alpha tropomyosin;
PDBTitle: structure of tropomyosin's mid-region: bending and binding2 sites for actin

Phyre2

PDB 1bg1 chain A

3D model

Region: 24 - 196
Aligned: 173
Modelled: 173
Confidence: 94.5%
Identity: 13%
PDB header:transcription/dna
Chain: A: PDB Molecule:protein (transcription factor stat3b);
PDBTitle: transcription factor stat3b/dna complex

Phyre2

PDB 3l9o chain A

3D model

Region: 17 - 311
Aligned: 268
Modelled: 268
Confidence: 94.2%
Identity: 8%
PDB header:hydrolase
Chain: A: PDB Molecule:atp-dependent rna helicase dob1;
PDBTitle: crystal structure of mtr4, a co-factor of the nuclear exosome

Phyre2

PDB 3g67 chain A

3D model

Region: 30 - 297
Aligned: 210
Modelled: 210
Confidence: 94.0%
Identity: 13%
PDB header:signaling protein
Chain: A: PDB Molecule:methyl-accepting chemotaxis protein;
PDBTitle: crystal structure of a soluble chemoreceptor from thermotoga2 maritima

Phyre2

PDB 3na7 chain A

3D model

Region: 6 - 166
Aligned: 161
Modelled: 161
Confidence: 93.7%
Identity: 10%
PDB header:gene regulation, chaperone
Chain: A: PDB Molecule:hp0958;
PDBTitle: 2.2 angstrom structure of the hp0958 protein from helicobacter pylori2 ccug 17874

Phyre2

PDB 1bf5 chain A

3D model

Region: 15 - 171
Aligned: 157
Modelled: 157
Confidence: 93.7%
Identity: 8%
PDB header:gene regulation/dna
Chain: A: PDB Molecule:signal transducer and activator of transcription
PDBTitle: tyrosine phosphorylated stat-1/dna complex

Phyre2

PDB 3ol1 chain A

3D model

Region: 17 - 107
Aligned: 91
Modelled: 91
Confidence: 93.7%
Identity: 8%
PDB header:structural protein
Chain: A: PDB Molecule:vimentin;
PDBTitle: crystal structure of vimentin (fragment 144-251) from homo sapiens,2 northeast structural genomics consortium target hr4796b

Phyre2

PDB 3o0z chain D

3D model

Region: 19 - 166
Aligned: 145
Modelled: 148
Confidence: 93.7%
Identity: 11%
PDB header:transferase
Chain: D: PDB Molecule:rho-associated protein kinase 1;
PDBTitle: crystal structure of a coiled-coil domain from human rock i

Phyre2

PDB 3cwg chain A

3D model

Region: 20 - 171
Aligned: 152
Modelled: 152
Confidence: 93.5%
Identity: 11%
PDB header:transcription
Chain: A: PDB Molecule:signal transducer and activator of transcription
PDBTitle: unphosphorylated mouse stat3 core fragment

Phyre2
1

c1c1gA_
2

c2ch7A_
3

c2oevA_
4

c2efrB_
5

c2oexB_
6

c1ciiA_
7

c3ojaB_
8

c1yvlB_
9

c2d3eD_
10

c3u59C_
11

c2fxmB_
12

c2b9cA_
13

c1bg1A_
14

c3l9oA_
15

c3g67A_
16

c3na7A_
17

c1bf5A_
18

c3ol1A_
19

c3o0zD_
20

c3cwgA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1c1gA_



99.0 6 PDB header:contractile protein
Chain: A: PDB Molecule:tropomyosin;
PDBTitle: crystal structure of tropomyosin at 7 angstroms resolution2 in the spermine-induced crystal form
2c2ch7A_



98.4 10 PDB header:chemotaxis
Chain: A: PDB Molecule:methyl-accepting chemotaxis protein;
PDBTitle: crystal structure of the cytoplasmic domain of a bacterial2 chemoreceptor from thermotoga maritima
3c2oevA_



97.6 7 PDB header:protein transport
Chain: A: PDB Molecule:programmed cell death 6-interacting protein;
PDBTitle: crystal structure of alix/aip1
4c2efrB_



97.3 12 PDB header:contractile protein
Chain: B: PDB Molecule:general control protein gcn4 and tropomyosin 1 alpha chain;
PDBTitle: crystal structure of the c-terminal tropomyosin fragment with n- and2 c-terminal extensions of the leucine zipper at 1.8 angstroms3 resolution
5c2oexB_



97.1 8 PDB header:protein transport
Chain: B: PDB Molecule:programmed cell death 6-interacting protein;
PDBTitle: structure of alix/aip1 v domain
6c1ciiA_



96.9 12 PDB header:transmembrane protein
Chain: A: PDB Molecule:colicin ia;
PDBTitle: colicin ia
7c3ojaB_



96.3 10 PDB header:protein binding
Chain: B: PDB Molecule:anopheles plasmodium-responsive leucine-rich repeat protein
PDBTitle: crystal structure of lrim1/apl1c complex
8c1yvlB_



95.3 9 PDB header:signaling protein
Chain: B: PDB Molecule:signal transducer and activator of transcription
PDBTitle: structure of unphosphorylated stat1
9c2d3eD_



95.3 13 PDB header:contractile protein
Chain: D: PDB Molecule:general control protein gcn4 and tropomyosin 1
PDBTitle: crystal structure of the c-terminal fragment of rabbit2 skeletal alpha-tropomyosin
10c3u59C_



94.9 6 PDB header:contractile protein
Chain: C: PDB Molecule:tropomyosin beta chain;
PDBTitle: n-terminal 98-aa fragment of smooth muscle tropomyosin beta
11c2fxmB_



94.6 8 PDB header:contractile protein
Chain: B: PDB Molecule:myosin heavy chain, cardiac muscle beta isoform;
PDBTitle: structure of the human beta-myosin s2 fragment
12c2b9cA_



94.5 9 PDB header:contractile protein
Chain: A: PDB Molecule:striated-muscle alpha tropomyosin;
PDBTitle: structure of tropomyosin's mid-region: bending and binding2 sites for actin
13c1bg1A_



94.5 13 PDB header:transcription/dna
Chain: A: PDB Molecule:protein (transcription factor stat3b);
PDBTitle: transcription factor stat3b/dna complex
14c3l9oA_



94.2 8 PDB header:hydrolase
Chain: A: PDB Molecule:atp-dependent rna helicase dob1;
PDBTitle: crystal structure of mtr4, a co-factor of the nuclear exosome
15c3g67A_



94.0 13 PDB header:signaling protein
Chain: A: PDB Molecule:methyl-accepting chemotaxis protein;
PDBTitle: crystal structure of a soluble chemoreceptor from thermotoga2 maritima
16c3na7A_



93.7 10 PDB header:gene regulation, chaperone
Chain: A: PDB Molecule:hp0958;
PDBTitle: 2.2 angstrom structure of the hp0958 protein from helicobacter pylori2 ccug 17874
17c1bf5A_



93.7 8 PDB header:gene regulation/dna
Chain: A: PDB Molecule:signal transducer and activator of transcription
PDBTitle: tyrosine phosphorylated stat-1/dna complex
18c3ol1A_



93.7 8 PDB header:structural protein
Chain: A: PDB Molecule:vimentin;
PDBTitle: crystal structure of vimentin (fragment 144-251) from homo sapiens,2 northeast structural genomics consortium target hr4796b
19c3o0zD_



93.7 11 PDB header:transferase
Chain: D: PDB Molecule:rho-associated protein kinase 1;
PDBTitle: crystal structure of a coiled-coil domain from human rock i
20c3cwgA_



93.5 11 PDB header:transcription
Chain: A: PDB Molecule:signal transducer and activator of transcription
PDBTitle: unphosphorylated mouse stat3 core fragment
21c3ghgK_



not modelled 93.4 10 PDB header:blood clotting
Chain: K: PDB Molecule:fibrinogen beta chain;
PDBTitle: crystal structure of human fibrinogen
22c4a55B_



not modelled 93.0 5 PDB header:transferase
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit alpha;
PDBTitle: crystal structure of p110alpha in complex with ish2 of p85alpha and2 the inhibitor pik-108
23c2gl2B_



not modelled 92.7 13 PDB header:cell adhesion
Chain: B: PDB Molecule:adhesion a;
PDBTitle: crystal structure of the tetra muntant (t66g,r67g,f68g,2 y69g) of bacterial adhesin fada
24c1deqO_



not modelled 92.2 12 PDB header:
PDB COMPND:
25c1qu7A_



not modelled 90.9 12 PDB header:signaling protein
Chain: A: PDB Molecule:methyl-accepting chemotaxis protein i;
PDBTitle: four helical-bundle structure of the cytoplasmic domain of a serine2 chemotaxis receptor
26c2y3aB_



not modelled 89.5 8 PDB header:transferase
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta;
PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
27c1y4cA_



not modelled 89.1 13 PDB header:de novo protein
Chain: A: PDB Molecule:maltose binding protein fused with designed
PDBTitle: designed helical protein fusion mbp
28c1ei3E_



not modelled 88.6 6 PDB header:
PDB COMPND:
29c2v66C_



not modelled 87.9 9 PDB header:structural protein
Chain: C: PDB Molecule:nuclear distribution protein nude-like 1;
PDBTitle: crystal structure of the coiled-coil domain of ndel1 (a.a.2 58 to 169)c
30c2wpqA_



not modelled 86.8 8 PDB header:membrane protein
Chain: A: PDB Molecule:trimeric autotransporter adhesin fragment;
PDBTitle: salmonella enterica sada 479-519 fused to gcn4 adaptors (2 sadak3, in-register fusion)
31c1deqF_



not modelled 85.9 11 PDB header:
PDB COMPND:
32c2dq3A_



not modelled 83.9 16 PDB header:ligase
Chain: A: PDB Molecule:seryl-trna synthetase;
PDBTitle: crystal structure of aq_298
33c1deqD_



not modelled 83.1 8 PDB header:
PDB COMPND:
34c2v1yB_



not modelled 80.9 8 PDB header:transferase
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit alpha;
PDBTitle: structure of a phosphoinositide 3-kinase alpha adaptor-2 binding domain (abd) in a complex with the ish2 domain3 from p85 alpha
35c2v71A_



not modelled 80.2 13 PDB header:nuclear protein
Chain: A: PDB Molecule:nuclear distribution protein nude-like 1;
PDBTitle: coiled-coil region of nudel
36c1hciB_



not modelled 80.0 8 PDB header:triple-helix coiled coil
Chain: B: PDB Molecule:alpha-actinin 2;
PDBTitle: crystal structure of the rod domain of alpha-actinin
37c1ei3C_



not modelled 79.0 8 PDB header:
PDB COMPND:
38c3dtpA_



not modelled 78.9 10 PDB header:contractile protein
Chain: A: PDB Molecule:myosin 2 heavy chain chimera of smooth and
PDBTitle: tarantula heavy meromyosin obtained by flexible docking to2 tarantula muscle thick filament cryo-em 3d-map
39c3u1aC_



not modelled 77.0 6 PDB header:contractile protein
Chain: C: PDB Molecule:smooth muscle tropomyosin alpha;
PDBTitle: n-terminal 81-aa fragment of smooth muscle tropomyosin alpha
40c2e7sM_



not modelled 75.8 14 PDB header:endocytosis/exocytosis
Chain: M: PDB Molecule:rab guanine nucleotide exchange factor sec2;
PDBTitle: crystal structure of the yeast sec2p gef domain
41c3ojaA_



not modelled 73.8 10 PDB header:protein binding
Chain: A: PDB Molecule:leucine-rich immune molecule 1;
PDBTitle: crystal structure of lrim1/apl1c complex
42c1jchC_



not modelled 73.6 9 PDB header:ribosome inhibitor, hydrolase
Chain: C: PDB Molecule:colicin e3;
PDBTitle: crystal structure of colicin e3 in complex with its immunity protein
43c3hnwB_



not modelled 72.6 7 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a basic coiled-coil protein of unknown function2 from eubacterium eligens atcc 27750
44c2i1jA_



not modelled 69.9 9 PDB header:cell adhesion, membrane protein
Chain: A: PDB Molecule:moesin;
PDBTitle: moesin from spodoptera frugiperda at 2.1 angstroms resolution
45c1l8dB_



not modelled 69.4 13 PDB header:replication
Chain: B: PDB Molecule:dna double-strand break repair rad50 atpase;
PDBTitle: rad50 coiled-coil zn hook
46c3a7pB_



not modelled 69.4 15 PDB header:protein transport
Chain: B: PDB Molecule:autophagy protein 16;
PDBTitle: the crystal structure of saccharomyces cerevisiae atg16
47c2qihA_



not modelled 66.3 13 PDB header:cell adhesion
Chain: A: PDB Molecule:protein uspa1;
PDBTitle: crystal structure of 527-665 fragment of uspa1 protein from2 moraxella catarrhalis
48c3hizB_



not modelled 64.6 8 PDB header:transferase/oncoprotein
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit
PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha
49c3iv1F_



not modelled 56.7 11 PDB header:hydrolase
Chain: F: PDB Molecule:tumor susceptibility gene 101 protein;
PDBTitle: coiled-coil domain of tumor susceptibility gene 101
50c3r6nA_



not modelled 56.2 7 PDB header:cell adhesion
Chain: A: PDB Molecule:desmoplakin;
PDBTitle: crystal structure of a rigid four spectrin repeat fragment of the2 human desmoplakin plakin domain
51c2rd0B_



not modelled 53.3 9 PDB header:transferase/oncoprotein
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit alpha;
PDBTitle: structure of a human p110alpha/p85alpha complex
52c3qh9A_



not modelled 49.8 16 PDB header:structural protein
Chain: A: PDB Molecule:liprin-beta-2;
PDBTitle: human liprin-beta2 coiled-coil
53c2eqbC_



not modelled 43.9 12 PDB header:endocytosis/exocytosis
Chain: C: PDB Molecule:rab guanine nucleotide exchange factor sec2;
PDBTitle: crystal structure of the rab gtpase sec4p, the sec2p gef2 domain, and phosphate complex
54c3layF_



not modelled 42.0 14 PDB header:metal binding protein
Chain: F: PDB Molecule:zinc resistance-associated protein;
PDBTitle: alpha-helical barrel formed by the decamer of the zinc resistance-2 associated protein (stm4172) from salmonella enterica subsp. enterica3 serovar typhimurium str. lt2
55c2jeeA_



not modelled 38.6 12 PDB header:cell cycle
Chain: A: PDB Molecule:yiiu;
PDBTitle: xray structure of e. coli yiiu
56c1ic2B_



not modelled 34.7 9 PDB header:contractile protein
Chain: B: PDB Molecule:tropomyosin alpha chain, skeletal muscle;
PDBTitle: deciphering the design of the tropomyosin molecule
57c2v4hA_



not modelled 32.9 18 PDB header:transcription
Chain: A: PDB Molecule:nf-kappa-b essential modulator;
PDBTitle: nemo cc2-lz domain - 1d5 darpin complex
58c2xdjF_



not modelled 32.8 10 PDB header:unknown function
Chain: F: PDB Molecule:uncharacterized protein ybgf;
PDBTitle: crystal structure of the n-terminal domain of e.coli ybgf
59c3ipkA_



not modelled 30.1 11 PDB header:cell adhesion
Chain: A: PDB Molecule:agi/ii;
PDBTitle: crystal structure of a3vp1 of agi/ii of streptococcus mutans
60c1sjjB_



not modelled 29.7 10 PDB header:contractile protein
Chain: B: PDB Molecule:actinin;
PDBTitle: cryo-em structure of chicken gizzard smooth muscle alpha-2 actinin
61c2no2A_



not modelled 29.4 10 PDB header:cell adhesion
Chain: A: PDB Molecule:huntingtin-interacting protein 1;
PDBTitle: crystal structure of the dllrkn-containing coiled-coil2 domain of huntingtin-interacting protein 1
62d1seta1



not modelled 28.2 11 Fold:Long alpha-hairpin
Superfamily:tRNA-binding arm
Family:Seryl-tRNA synthetase (SerRS)
63c3m9bK_



not modelled 24.8 5 PDB header:chaperone
Chain: K: PDB Molecule:proteasome-associated atpase;
PDBTitle: crystal structure of the amino terminal coiled coil domain and the2 inter domain of the mycobacterium tuberculosis proteasomal atpase mpa
64c3n4xB_



not modelled 22.4 8 PDB header:replication
Chain: B: PDB Molecule:monopolin complex subunit csm1;
PDBTitle: structure of csm1 full-length
65c1ci6A_



not modelled 22.0 14 PDB header:transcription
Chain: A: PDB Molecule:transcription factor atf-4;
PDBTitle: transcription factor atf4-c/ebp beta bzip heterodimer
66c3qo8A_



not modelled 21.7 14 PDB header:ligase
Chain: A: PDB Molecule:seryl-trna synthetase, cytoplasmic;
PDBTitle: crystal structure of seryl-trna synthetase from candida albicans
67c1gd2G_



not modelled 21.3 10 PDB header:transcription/dna
Chain: G: PDB Molecule:transcription factor pap1;
PDBTitle: crystal structure of bzip transcription factor pap1 bound2 to dna
68c1gk4A_



not modelled 20.4 8 PDB header:vimentin
Chain: A: PDB Molecule:vimentin;
PDBTitle: human vimentin coil 2b fragment (cys2)
69c3q0xA_



not modelled 18.8 13 PDB header:structural protein
Chain: A: PDB Molecule:centriole protein;
PDBTitle: n-terminal coiled-coil dimer domain of c. reinhardtii sas-6 homolog2 bld12p
70d2ap3a1



not modelled 17.9 7 Fold:Four-helical up-and-down bundle
Superfamily:MW0975(SA0943)-like
Family:MW0975(SA0943)-like
71c1x8yA_



not modelled 17.6 11 PDB header:structural protein
Chain: A: PDB Molecule:lamin a/c;
PDBTitle: human lamin coil 2b
72c2wt7B_



not modelled 16.7 14 PDB header:transcription
Chain: B: PDB Molecule:transcription factor mafb;
PDBTitle: crystal structure of the bzip heterodimeric complex2 mafb:cfos bound to dna
73c1wt6B_



not modelled 16.5 20 PDB header:transferase
Chain: B: PDB Molecule:myotonin-protein kinase;
PDBTitle: coiled-coil domain of dmpk
74c2zvnF_



not modelled 15.8 17 PDB header:signaling protein/transcription
Chain: F: PDB Molecule:nf-kappa-b essential modulator;
PDBTitle: nemo cozi domain incomplex with diubiquitin in p2121212 space group
75c2x7aB_



not modelled 15.5 5 PDB header:immune system
Chain: B: PDB Molecule:bone marrow stromal antigen 2;
PDBTitle: structural basis of hiv-1 tethering to membranes by the2 bst2-tetherin ectodomain
76c2bsgA_



not modelled 15.5 9 PDB header:viral protein
Chain: A: PDB Molecule:fibritin;
PDBTitle: the modeled structure of fibritin (gpwac) of bacteriophage2 t4 based on cryo-em reconstruction of the extended tail of3 bacteriophage t4
77c2pmsD_



not modelled 15.5 11 PDB header:metal transport, hydrolase
Chain: D: PDB Molecule:pneumococcal surface protein a (pspa);
PDBTitle: crystal structure of the complex of human lactoferrin n-lobe and2 lactoferrin-binding domain of pneumococcal surface protein a
78c1fosF_



not modelled 15.4 10 PDB header:transcription/dna
Chain: F: PDB Molecule:c-jun proto-oncogene protein;
PDBTitle: two human c-fos:c-jun:dna complexes
79c2ke4A_



not modelled 15.4 12 PDB header:membrane protein
Chain: A: PDB Molecule:cdc42-interacting protein 4;
PDBTitle: the nmr structure of the tc10 and cdc42 interacting domain2 of cip4
80c3batB_



not modelled 15.2 14 PDB header:contractile protein
Chain: B: PDB Molecule:myosin heavy chain, striated muscle/general
PDBTitle: crystal structure of the n-terminal region of the scallop2 myosin rod, monoclinic (p21) form
81c3cvfA_



not modelled 14.8 18 PDB header:signaling protein
Chain: A: PDB Molecule:homer protein homolog 3;
PDBTitle: crystal structure of the carboxy terminus of homer3
82c1n73C_



not modelled 14.6 6 PDB header:blood clotting
Chain: C: PDB Molecule:fibrin gamma chain;
PDBTitle: fibrin d-dimer, lamprey complexed with the peptide ligand: gly-his-2 arg-pro-amide
83c2hpcF_



not modelled 13.3 9 PDB header:blood clotting
Chain: F: PDB Molecule:fibrinogen, gamma polypeptide;
PDBTitle: crystal structure of fragment d from human fibrinogen complexed with2 gly-pro-arg-pro-amide.
84c1t2kD_



not modelled 11.4 10 PDB header:transcription/dna
Chain: D: PDB Molecule:cyclic-amp-dependent transcription factor atf-2;
PDBTitle: structure of the dna binding domains of irf3, atf-2 and jun2 bound to dna
85c2p22C_



not modelled 11.2 15 PDB header:transport protein
Chain: C: PDB Molecule:protein srn2;
PDBTitle: structure of the yeast escrt-i heterotetramer core
86c1g8xB_



not modelled 10.9 8 PDB header:structural protein
Chain: B: PDB Molecule:myosin ii heavy chain fused to alpha-actinin 3;
PDBTitle: structure of a genetically engineered molecular motor
87c3cveC_



not modelled 10.7 17 PDB header:signaling protein
Chain: C: PDB Molecule:homer protein homolog 1;
PDBTitle: crystal structure of the carboxy terminus of homer1
88c1yv0I_



not modelled 10.4 8 PDB header:contractile protein
Chain: I: PDB Molecule:troponin i, fast skeletal muscle;
PDBTitle: crystal structure of skeletal muscle troponin in the ca2+-2 free state
89c1junB_



not modelled 10.4 11 PDB header:transcription regulation
Chain: B: PDB Molecule:c-jun homodimer;
PDBTitle: nmr study of c-jun homodimer
90c3mkxC_



not modelled 9.9 13 PDB header:antiviral protein
Chain: C: PDB Molecule:bone marrow stromal antigen 2;
PDBTitle: crystal structure of bst2/tetherin
91c3m06F_



not modelled 9.6 10 PDB header:protein binding
Chain: F: PDB Molecule:tnf receptor-associated factor 2;
PDBTitle: crystal structure of traf2
92c1fosE_



not modelled 9.2 13 PDB header:transcription/dna
Chain: E: PDB Molecule:p55-c-fos proto-oncogene protein;
PDBTitle: two human c-fos:c-jun:dna complexes
93c1u4qB_



not modelled 9.1 12 PDB header:structural protein
Chain: B: PDB Molecule:spectrin alpha chain, brain;
PDBTitle: crystal structure of repeats 15, 16 and 17 of chicken brain2 alpha spectrin
94c1ru7B_



not modelled 9.0 15 PDB header:viral protein
Chain: B: PDB Molecule:hemagglutinin;
PDBTitle: 1934 human h1 hemagglutinin
95c2xgjA_



not modelled 8.8 18 PDB header:hydrolase/rna
Chain: A: PDB Molecule:atp-dependent rna helicase dob1;
PDBTitle: structure of mtr4, a dexh helicase involved in nuclear rna2 processing and surveillance
96c2e43A_



not modelled 8.7 11 PDB header:transcription/dna
Chain: A: PDB Molecule:ccaat/enhancer-binding protein beta;
PDBTitle: crystal structure of c/ebpbeta bzip homodimer k269a mutant2 bound to a high affinity dna fragment
97c3lssA_



not modelled 8.6 9 PDB header:ligase
Chain: A: PDB Molecule:seryl-trna synthetase;
PDBTitle: trypanosoma brucei seryl-trna synthetase in complex with atp
98c1ik9B_



not modelled 8.0 8 PDB header:gene regulation/ligase
Chain: B: PDB Molecule:dna repair protein xrcc4;
PDBTitle: crystal structure of a xrcc4-dna ligase iv complex
99c2w6aB_



not modelled 7.9 11 PDB header:signaling protein
Chain: B: PDB Molecule:arf gtpase-activating protein git1;
PDBTitle: x-ray structure of the dimeric git1 coiled-coil domain

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0