Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	E	P	L	L	I	A	R	T	P	D	T	E	L	F	L	L	P	G	M	A	N	R	H	G	L	I	T	G	A	T	G	T	G	K	T	V	T	L	Q	K	L	A	E	S	L	S	E	I	G	V	P	V	F	M	A	D	V	K
Secondary structure
SS confidence
Disorder		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	D	L	T	G	V	A	Q	A	G	T	V	S	E	K	L	L	A	R	L	K	N	I	G	V	N	D	W	Q	P	H	A	N	P	V	V	V	W	D	I	F	G	E	K	G	H	P	V	R	A	T	V	S	D	L	G	P	L	L	L
Secondary structure
SS confidence
Disorder											?	?	?	?																								?								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	R	L	L	N	L	N	D	V	Q	S	G	V	L	N	I	I	F	R	I	A	D	D	Q	G	L	L	L	L	D	F	K	D	L	R	A	I	T	Q	Y	I	G	D	N	A	K	S	F	Q	N	Q	Y	G	N	I	S	S	A	S	V
Secondary structure
SS confidence
Disorder							?		?																																														?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		G	A	I	Q	R	G	L	L	S	L	E	Q	Q	G	A	A	H	F	F	G	E	P	M	L	D	I	K	D	W	M	R	T	D	A	N	G	K	G	V	I	N	I	L	S	A	E	K	L	Y	Q	M	P	K	L	Y	A	A	S	L	L
Secondary structure
SS confidence
Disorder														?	?	?	?	?																		?											?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		W	M	L	S	E	L	Y	E	Q	L	P	E	A	G	D	L	E	K	P	K	L	V	F	F	F	D	E	A	H	L	L	F	N	D	A	P	Q	V	L	L	D	K	I	E	Q	V	I	R	L	I	R	S	K	G	V	G	V	W	F	V
Secondary structure
SS confidence
Disorder													?	?	?	?																					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		S	Q	N	P	S	D	I	P	D	N	V	L	G	Q	L	G	N	R	V	Q	H	A	L	R	A	F	T	P	K	D	Q	K	A	V	K	A	A	A	Q	T	M	R	A	N	P	A	F	D	T	E	K	A	I	Q	E	L	G	T	G	E
Secondary structure
SS confidence
Disorder								?																																		?	?	?	?	?	?	?						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		A	L	I	S	F	L	D	A	K	G	S	P	S	V	V	E	R	A	M	V	I	A	P	C	S	R	M	G	P	V	T	E	D	E	R	N	G	L	I	N	H	S	P	V	Y	G	K	Y	E	D	E	V	D	R	E	S	A	Y	E	M
Secondary structure
SS confidence
Disorder								?	?	?	?	?						?	?	?	?	?	?	?	?	?	?	?	?	?	?										?		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		L	Q	K	G	F	Q	A	S	T	E	Q	Q	N	N	P	P	A	K	G	K	E	V	A	V	D	D	G	I	L	G	G	L	K	D	I	L	F	G	T	T	G	P	R	G	G	K	K	D	G	V	V	Q	T	M	A	K	S	A	A	R
Secondary structure
SS confidence
Disorder			?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500
Sequence		Q	V	T	N	Q	I	V	R	G	M	L	G	S	L	L	G	G	R	R	R
Secondary structure
SS confidence
Disorder													?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2iut chain A Region: 1 - 410 Aligned: 273 Modelled: 285 Confidence: 100.0% Identity: 21% PDB header:membrane protein Chain: A: PDB Molecule:dna translocase ftsk; PDBTitle: p. aeruginosa ftsk motor domain, dimeric Phyre2 PDB 2iuu chain E Region: 1 - 410 Aligned: 273 Modelled: 285 Confidence: 100.0% Identity: 21% PDB header:membrane protein Chain: E: PDB Molecule:dna translocase ftsk; PDBTitle: p. aeruginosa ftsk motor domain, hexamer Phyre2 PDB 1e9r chain A Region: 2 - 390 Aligned: 357 Modelled: 368 Confidence: 100.0% Identity: 16% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: RecA protein-like (ATPase-domain) Phyre2 PDB 2ius chain B Region: 4 - 411 Aligned: 263 Modelled: 275 Confidence: 100.0% Identity: 20% PDB header:membrane protein Chain: B: PDB Molecule:dna translocase ftsk; PDBTitle: e. coli ftsk motor domain Phyre2 PDB 2ve8 chain A domain 1 Region: 444 - 500 Aligned: 57 Modelled: 57 Confidence: 99.4% Identity: 12% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: FtsK C-terminal domain-like Phyre2 PDB 2j5p chain A domain 1 Region: 441 - 500 Aligned: 60 Modelled: 60 Confidence: 99.4% Identity: 10% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: FtsK C-terminal domain-like Phyre2 PDB 2r2a chain B Region: 262 - 322 Aligned: 61 Modelled: 61 Confidence: 98.4% Identity: 16% PDB header:toxin Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of n-terminal domain of zonular occludens toxin from2 neisseria meningitidis Phyre2 PDB 3b9p chain A Region: 16 - 336 Aligned: 142 Modelled: 147 Confidence: 97.9% Identity: 24% PDB header:hydrolase Chain: A: PDB Molecule:cg5977-pa, isoform a; PDBTitle: spastin Phyre2 PDB 3l9o chain A Region: 23 - 367 Aligned: 199 Modelled: 207 Confidence: 97.8% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:atp-dependent rna helicase dob1; PDBTitle: crystal structure of mtr4, a co-factor of the nuclear exosome Phyre2 PDB 2w0m chain A Region: 26 - 312 Aligned: 147 Modelled: 153 Confidence: 97.5% Identity: 24% PDB header:unknown function Chain: A: PDB Molecule:sso2452; PDBTitle: crystal structure of sso2452 from sulfolobus solfataricus2 p2 Phyre2 PDB 1byi chain A Region: 23 - 59 Aligned: 37 Modelled: 37 Confidence: 97.4% Identity: 24% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nitrogenase iron protein-like Phyre2 PDB 2i3b chain A domain 1 Region: 23 - 60 Aligned: 38 Modelled: 38 Confidence: 97.4% Identity: 39% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: RecA protein-like (ATPase-domain) Phyre2 PDB 3hu2 chain C Region: 23 - 337 Aligned: 136 Modelled: 141 Confidence: 97.3% Identity: 28% PDB header:transport protein Chain: C: PDB Molecule:transitional endoplasmic reticulum atpase; PDBTitle: structure of p97 n-d1 r86a mutant in complex with atpgs Phyre2 PDB 1xwi chain A Region: 23 - 336 Aligned: 136 Modelled: 140 Confidence: 97.3% Identity: 22% PDB header:protein transport Chain: A: PDB Molecule:skd1 protein; PDBTitle: crystal structure of vps4b Phyre2 PDB 1vma chain A domain 2 Region: 26 - 58 Aligned: 33 Modelled: 33 Confidence: 97.3% Identity: 36% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nitrogenase iron protein-like Phyre2 PDB 1cr2 chain A Region: 26 - 320 Aligned: 160 Modelled: 173 Confidence: 97.2% Identity: 18% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: RecA protein-like (ATPase-domain) Phyre2 PDB 2d3w chain B Region: 23 - 320 Aligned: 189 Modelled: 197 Confidence: 97.1% Identity: 20% PDB header:biosynthetic protein Chain: B: PDB Molecule:probable atp-dependent transporter sufc; PDBTitle: crystal structure of escherichia coli sufc, an atpase2 compenent of the suf iron-sulfur cluster assembly machinery Phyre2 PDB 2qy9 chain A domain 2 Region: 23 - 58 Aligned: 36 Modelled: 36 Confidence: 97.1% Identity: 36% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nitrogenase iron protein-like Phyre2 PDB 3of5 chain A Region: 24 - 59 Aligned: 36 Modelled: 36 Confidence: 97.1% Identity: 25% PDB header:ligase Chain: A: PDB Molecule:dethiobiotin synthetase; PDBTitle: crystal structure of a dethiobiotin synthetase from francisella2 tularensis subsp. tularensis schu s4 Phyre2 PDB 1g6o chain A Region: 23 - 63 Aligned: 40 Modelled: 41 Confidence: 97.1% Identity: 18% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: RecA protein-like (ATPase-domain) Phyre2 1 c2iutA_ 2 c2iuuE_ 3 d1e9ra_ 4 c2iusB_ 5 d2ve8a1 6 d2j5pa1 7 c2r2aB_ 8 c3b9pA_ 9 c3l9oA_ 10 c2w0mA_ 11 d1byia_ 12 d2i3ba1 13 c3hu2C_ 14 c1xwiA_ 15 d1vmaa2 16 d1cr2a_ 17 c2d3wB_ 18 d2qy9a2 19 c3of5A_ 20 d1g6oa_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499