Phyre 2 Results for P08394

Email	l.a.kelley@imperial.ac.uk
Description	P08394
Date	Thu Jan 5 11:01:26 GMT 2012
Unique Job ID	ec26ad5c8cd5bf72

Summary

Top model

Image coloured by rainbow N → C terminus

Model (left) based on template c1w36E_

Top template information

PDB header:recombination
Chain: E: PDB Molecule:exodeoxyribonuclease v beta chain;
PDBTitle: recbcd:dna complex

Confidence and coverage

Confidence:

100.0%

Coverage:

98%

1158 residues ( 98% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M S D V A E T L D P L R L P L Q G E R L I E A S A G T G K T F T I A A L Y L R L L L G L G G S A A F P R P L T V E E L L

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ?
?
? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence V V T F T E A A T A E L R G R I R S N I H E L R I A C L R E T T D N P L Y E R L L E E I D D K A Q A A Q W L L L A E R Q

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence M D E A A V F T I H G F C Q R M L N L N A F E S G M L F E Q Q L I E D E S L L R Y Q A C A D F W R R H C Y P L P R E I A

Secondary structure

SS confidence

Disorder
?

Disorder confidence

. . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240

Sequence Q V V F E T W K G P Q A L L R D I N R Y L Q G E A P V I K A P P P D D E T L A S R H A Q I V A R I D T V K Q Q W R D A V

Secondary structure

SS confidence

Disorder
? ? ? ?

Disorder confidence

. . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280 . . . . . . . . . 290 . . . . . . . . . 300

Sequence G E L D A L I E S S G I D R R K F N R S N Q A K W I D K I S A W A E E E T N S Y Q L P E S L E K F S Q R F L E D R T K A

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350 . . . . . . . . . 360

Sequence G G E T P R H P L F E A I D Q L L A E P L S I R D L V I T R A L A E I R E T V A R E K R R R G E L G F D D M L S R L D S

Secondary structure

SS confidence

Disorder
? ? ? ?

Disorder confidence

. . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence A L R S E S G E V L A A A I R T R F P V A M I D E F Q D T D P Q Q Y R I F R R I W H H Q P E T A L L L I G D P K Q A I Y

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480

Sequence A F R G A D I F T Y M K A R S E V H A H Y T L D T N W R S A P G M V N S V N K L F S Q T D D A F M F R E I P F I P V K S

Secondary structure

SS confidence

Disorder
?
? ? ? ? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 490 . . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540

Sequence A G K N Q A L R F V F K G E T Q P A M K M W L M E G E S C G V G D Y Q S T M A Q V C A A Q I R D W L Q A G Q R G E A L L

Secondary structure

SS confidence

Disorder ?
? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 550 . . . . . . . . . 560 . . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600

Sequence M N G D D A R P V R A S D I S V L V R S R Q E A A Q V R D A L T L L E I P S V Y L S N R D S V F E T L E A Q E M L W L L

Secondary structure

SS confidence

Disorder ?
?
? ? ? ?

Disorder confidence

. . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630 . . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660

Sequence Q A V M T P E R E N T L R S A L A T S M M G L N A L D I E T L N N D E H A W D V V V E E F D G Y R Q I W R K R G V M P M

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700 . . . . . . . . . 710 . . . . . . . . . 720

Sequence L R A L M S A R N I A E N L L A T A G G E R R L T D I L H I S E L L Q E A G T Q L E S E H A L V R W L S Q H I L E P D S

Secondary structure

SS confidence

Disorder
? ? ? ? ? ?
? ? ? ?

Disorder confidence

. . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770 . . . . . . . . . 780

Sequence N A S S Q Q M R L E S D K H L V Q I V T I H K S K G L E Y P L V W L P F I T N F R V Q E Q A F Y H D R H S F E A V L D L

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ?
?
?
? ? ?

Disorder confidence

. . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence N A A P E S V D L A E A E R L A E D L R L L Y V A L T R S V W H C S L G V A P L V R R R G D K K G D T D V H Q S A L G R

Secondary structure

SS confidence

Disorder
? ?
? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900

Sequence L L Q K G E P Q D A A G L R T C I E A L C D D D I A W Q T A Q T G D N Q P W Q V N D V S T A E L N A K T L Q R L P G D N

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ?
? ? ? ?
? ?
? ?

Disorder confidence

. . . . . . . . . 910 . . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960

Sequence W R V T S Y S G L Q Q R G H G I A Q D L M P R L D V D A A G V A S V V E E P T L T P H Q F P R G A S P G T F L H S L F E

Secondary structure

SS confidence

Disorder
?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 970 . . . . . . . . . 980 . . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020

Sequence D L D F T Q P V D P N W V R E K L E L G G F E S Q W E P V L T E W I T A V L Q A P L N E T G V S L S Q L S A R N K Q V E

Secondary structure

SS confidence

Disorder
?
? ? ?

Disorder confidence

. . . . . . . . . 1030 . . . . . . . . . 1040 . . . . . . . . . 1050 . . . . . . . . . 1060 . . . . . . . . . 1070 . . . . . . . . . 1080

Sequence M E F Y L P I S E P L I A S Q L D T L I R Q F D P L S A G C P P L E F M Q V R G M L K G F I D L V F R H E G R Y Y L L D

Secondary structure

SS confidence

Disorder
? ? ?
? ? ? ?
?
? ?

Disorder confidence

. . . . . . . . . 1090 . . . . . . . . . 1100 . . . . . . . . . 1110 . . . . . . . . . 1120 . . . . . . . . . 1130 . . . . . . . . . 1140

Sequence Y K S N W L G E D S S A Y T Q Q A M A A A M Q A H R Y D L Q Y Q L Y T L A L H R Y L R H R I A D Y D Y E H H F G G V I Y

Secondary structure

SS confidence

Disorder
? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 1150 . . . . . . . . . 1160 . . . . . . . . . 1170 . . . . . . . . . 1180

Sequence L F L R G V D K E H P Q Q G I Y T T R P N A G L I A L M D E M F A G M T L E E A

Secondary structure

SS confidence

Disorder
?
? ? ? ? ? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered

Alpha helix

Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 1w36 chain E

Region: 1 - 1174
Aligned: 1158
Modelled: 1158
Confidence: 100.0%
Identity: 100%
PDB header:recombination
Chain: E: PDB Molecule:exodeoxyribonuclease v beta chain;
PDBTitle: recbcd:dna complex

Phyre2

PDB 2is6 chain B

Region: 10 - 850
Aligned: 593
Modelled: 616
Confidence: 100.0%
Identity: 23%
PDB header:hydrolase/dna
Chain: B: PDB Molecule:dna helicase ii;
PDBTitle: crystal structure of uvrd-dna-adpmgf3 ternary complex

Phyre2

PDB 1w36 chain B domain 1

Region: 1 - 485
Aligned: 469
Modelled: 469
Confidence: 100.0%
Identity: 99%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: Tandem AAA-ATPase domain

Phyre2

PDB 1uaa chain B

Region: 10 - 842
Aligned: 587
Modelled: 613
Confidence: 100.0%
Identity: 21%
PDB header:hydrolase/dna
Chain: B: PDB Molecule:protein (atp-dependent dna helicase rep.);
PDBTitle: e. coli rep helicase/dna complex

Phyre2

PDB 1w36 chain B domain 3

Region: 899 - 1174
Aligned: 276
Modelled: 276
Confidence: 100.0%
Identity: 100%
Fold: Restriction endonuclease-like
Superfamily: Restriction endonuclease-like
Family: Exodeoxyribonuclease V beta chain (RecB), C-terminal domain

Phyre2

PDB 2pjr chain F

Region: 10 - 712
Aligned: 491
Modelled: 505
Confidence: 100.0%
Identity: 23%
PDB header:hydrolase/dna
Chain: F: PDB Molecule:protein (helicase pcra);
PDBTitle: helicase product complex

Phyre2

PDB 1pjr chain A

Region: 16 - 846
Aligned: 581
Modelled: 595
Confidence: 100.0%
Identity: 23%
PDB header:helicase
Chain: A: PDB Molecule:pcra;
PDBTitle: structure of dna helicase

Phyre2

PDB 3lfu chain A

Region: 16 - 841
Aligned: 578
Modelled: 599
Confidence: 100.0%
Identity: 25%
PDB header:hydrolase
Chain: A: PDB Molecule:dna helicase ii;
PDBTitle: crystal structure of e. coli uvrd

Phyre2

PDB 1w36 chain B domain 2

Region: 486 - 880
Aligned: 395
Modelled: 395
Confidence: 100.0%
Identity: 100%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: Tandem AAA-ATPase domain

Phyre2

PDB 1w36 chain F

Region: 27 - 1119
Aligned: 830
Modelled: 896
Confidence: 100.0%
Identity: 13%
PDB header:recombination
Chain: F: PDB Molecule:exodeoxyribonuclease v gamma chain;
PDBTitle: recbcd:dna complex

Phyre2

PDB 1qhh chain B

Region: 330 - 629
Aligned: 256
Modelled: 260
Confidence: 100.0%
Identity: 22%
PDB header:hydrolase
Chain: B: PDB Molecule:protein (pcra (subunit));
PDBTitle: structure of dna helicase with adpnp

Phyre2

PDB 1uaa chain A domain 1

Region: 16 - 468
Aligned: 282
Modelled: 294
Confidence: 100.0%
Identity: 27%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: Tandem AAA-ATPase domain

Phyre2

PDB 1pjr chain A domain 1

Region: 16 - 464
Aligned: 275
Modelled: 287
Confidence: 100.0%
Identity: 28%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: Tandem AAA-ATPase domain

Phyre2

PDB 1pjr chain A domain 2

Region: 513 - 846
Aligned: 283
Modelled: 284
Confidence: 100.0%
Identity: 20%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: Tandem AAA-ATPase domain

Phyre2

PDB 1uaa chain A domain 2

Region: 504 - 843
Aligned: 296
Modelled: 304
Confidence: 100.0%
Identity: 17%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: Tandem AAA-ATPase domain

Phyre2

PDB 1w36 chain C domain 2

Region: 509 - 841
Aligned: 302
Modelled: 324
Confidence: 100.0%
Identity: 14%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: Tandem AAA-ATPase domain

Phyre2

PDB 2gk7 chain A

Region: 16 - 817
Aligned: 376
Modelled: 398
Confidence: 99.9%
Identity: 27%
PDB header:hydrolase
Chain: A: PDB Molecule:regulator of nonsense transcripts 1;
PDBTitle: structural and functional insights into the human upf1 helicase core

Phyre2

PDB 2wjy chain A

Region: 16 - 817
Aligned: 373
Modelled: 386
Confidence: 99.9%
Identity: 27%
PDB header:hydrolase
Chain: A: PDB Molecule:regulator of nonsense transcripts 1;
PDBTitle: crystal structure of the complex between human nonsense2 mediated decay factors upf1 and upf2 orthorhombic form

Phyre2

PDB 2xzl chain A

Region: 16 - 817
Aligned: 371
Modelled: 393
Confidence: 99.9%
Identity: 25%
PDB header:hydrolase/rna
Chain: A: PDB Molecule:atp-dependent helicase nam7;
PDBTitle: upf1-rna complex

Phyre2

PDB 3e1s chain A

Region: 16 - 819
Aligned: 324
Modelled: 330
Confidence: 99.9%
Identity: 28%
PDB header:hydrolase
Chain: A: PDB Molecule:exodeoxyribonuclease v, subunit recd;
PDBTitle: structure of an n-terminal truncation of deinococcus radiodurans recd2

Phyre2

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Detailed template information

#	Template	Alignment Coverage	3D Model	Confidence	% i.d.	Template Information

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server

Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]

If you use the binding site predictions from 3DLigandSite, please also cite:

3DLigandSite: predicting ligand-binding sites using similar structures.

Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]

Imperial College London

Lawrence Kelley, Benjamin Jefferys

Disclaimer

Terms and Conditions

Component software

Template detection: HHpred 1.51

Secondary structure prediction: Psi-pred 2.5

Disorder prediction: Disopred 2.4

Transmembrane prediction: Memsat_SVM

Multi-template modelling and ab initio: Poing 1.0

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence	M	S	D	V	A	E	T	L	D	P	L	R	L	P	L	Q	G	E	R	L	I	E	A	S	A	G	T	G	K	T	F	T	I	A	A	L	Y	L	R	L	L	L	G	L	G	G	S	A	A	F	P	R	P	L	T	V	E	E	L	L
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?	?	?			?																																			?	?	?	?	?		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence	V	V	T	F	T	E	A	A	T	A	E	L	R	G	R	I	R	S	N	I	H	E	L	R	I	A	C	L	R	E	T	T	D	N	P	L	Y	E	R	L	L	E	E	I	D	D	K	A	Q	A	A	Q	W	L	L	L	A	E	R	Q
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence	M	D	E	A	A	V	F	T	I	H	G	F	C	Q	R	M	L	N	L	N	A	F	E	S	G	M	L	F	E	Q	Q	L	I	E	D	E	S	L	L	R	Y	Q	A	C	A	D	F	W	R	R	H	C	Y	P	L	P	R	E	I	A
Secondary structure
SS confidence
Disorder																								?
Disorder confidence

	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence	Q	V	V	F	E	T	W	K	G	P	Q	A	L	L	R	D	I	N	R	Y	L	Q	G	E	A	P	V	I	K	A	P	P	P	D	D	E	T	L	A	S	R	H	A	Q	I	V	A	R	I	D	T	V	K	Q	Q	W	R	D	A	V
Secondary structure
SS confidence
Disorder																									?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence	G	E	L	D	A	L	I	E	S	S	G	I	D	R	R	K	F	N	R	S	N	Q	A	K	W	I	D	K	I	S	A	W	A	E	E	E	T	N	S	Y	Q	L	P	E	S	L	E	K	F	S	Q	R	F	L	E	D	R	T	K	A
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence	G	G	E	T	P	R	H	P	L	F	E	A	I	D	Q	L	L	A	E	P	L	S	I	R	D	L	V	I	T	R	A	L	A	E	I	R	E	T	V	A	R	E	K	R	R	R	G	E	L	G	F	D	D	M	L	S	R	L	D	S
Secondary structure
SS confidence
Disorder																																															?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	A	L	R	S	E	S	G	E	V	L	A	A	A	I	R	T	R	F	P	V	A	M	I	D	E	F	Q	D	T	D	P	Q	Q	Y	R	I	F	R	R	I	W	H	H	Q	P	E	T	A	L	L	L	I	G	D	P	K	Q	A	I	Y
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence	A	F	R	G	A	D	I	F	T	Y	M	K	A	R	S	E	V	H	A	H	Y	T	L	D	T	N	W	R	S	A	P	G	M	V	N	S	V	N	K	L	F	S	Q	T	D	D	A	F	M	F	R	E	I	P	F	I	P	V	K	S
Secondary structure
SS confidence
Disorder																		?																											?	?	?	?	?	?	?	?								?
Disorder confidence

	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence	A	G	K	N	Q	A	L	R	F	V	F	K	G	E	T	Q	P	A	M	K	M	W	L	M	E	G	E	S	C	G	V	G	D	Y	Q	S	T	M	A	Q	V	C	A	A	Q	I	R	D	W	L	Q	A	G	Q	R	G	E	A	L	L
Secondary structure
SS confidence
Disorder	?																										?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence	M	N	G	D	D	A	R	P	V	R	A	S	D	I	S	V	L	V	R	S	R	Q	E	A	A	Q	V	R	D	A	L	T	L	L	E	I	P	S	V	Y	L	S	N	R	D	S	V	F	E	T	L	E	A	Q	E	M	L	W	L	L
Secondary structure
SS confidence
Disorder	?		?																																									?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660
Sequence	Q	A	V	M	T	P	E	R	E	N	T	L	R	S	A	L	A	T	S	M	M	G	L	N	A	L	D	I	E	T	L	N	N	D	E	H	A	W	D	V	V	V	E	E	F	D	G	Y	R	Q	I	W	R	K	R	G	V	M	P	M
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720
Sequence	L	R	A	L	M	S	A	R	N	I	A	E	N	L	L	A	T	A	G	G	E	R	R	L	T	D	I	L	H	I	S	E	L	L	Q	E	A	G	T	Q	L	E	S	E	H	A	L	V	R	W	L	S	Q	H	I	L	E	P	D	S
Secondary structure
SS confidence
Disorder																																						?	?	?	?	?	?														?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780
Sequence	N	A	S	S	Q	Q	M	R	L	E	S	D	K	H	L	V	Q	I	V	T	I	H	K	S	K	G	L	E	Y	P	L	V	W	L	P	F	I	T	N	F	R	V	Q	E	Q	A	F	Y	H	D	R	H	S	F	E	A	V	L	D	L
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?	?	?	?	?	?	?	?																											?		?										?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	N	A	A	P	E	S	V	D	L	A	E	A	E	R	L	A	E	D	L	R	L	L	Y	V	A	L	T	R	S	V	W	H	C	S	L	G	V	A	P	L	V	R	R	R	G	D	K	K	G	D	T	D	V	H	Q	S	A	L	G	R
Secondary structure
SS confidence
Disorder			?	?																																				?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900
Sequence	L	L	Q	K	G	E	P	Q	D	A	A	G	L	R	T	C	I	E	A	L	C	D	D	D	I	A	W	Q	T	A	Q	T	G	D	N	Q	P	W	Q	V	N	D	V	S	T	A	E	L	N	A	K	T	L	Q	R	L	P	G	D	N
Secondary structure
SS confidence
Disorder																																?	?	?	?	?	?	?	?	?			?	?	?	?				?	?							?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960
Sequence	W	R	V	T	S	Y	S	G	L	Q	Q	R	G	H	G	I	A	Q	D	L	M	P	R	L	D	V	D	A	A	G	V	A	S	V	V	E	E	P	T	L	T	P	H	Q	F	P	R	G	A	S	P	G	T	F	L	H	S	L	F	E
Secondary structure
SS confidence
Disorder			?								?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020
Sequence	D	L	D	F	T	Q	P	V	D	P	N	W	V	R	E	K	L	E	L	G	G	F	E	S	Q	W	E	P	V	L	T	E	W	I	T	A	V	L	Q	A	P	L	N	E	T	G	V	S	L	S	Q	L	S	A	R	N	K	Q	V	E
Secondary structure
SS confidence
Disorder																																													?								?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080
Sequence	M	E	F	Y	L	P	I	S	E	P	L	I	A	S	Q	L	D	T	L	I	R	Q	F	D	P	L	S	A	G	C	P	P	L	E	F	M	Q	V	R	G	M	L	K	G	F	I	D	L	V	F	R	H	E	G	R	Y	Y	L	L	D
Secondary structure
SS confidence
Disorder									?	?	?															?	?	?	?			?					?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140
Sequence	Y	K	S	N	W	L	G	E	D	S	S	A	Y	T	Q	Q	A	M	A	A	A	M	Q	A	H	R	Y	D	L	Q	Y	Q	L	Y	T	L	A	L	H	R	Y	L	R	H	R	I	A	D	Y	D	Y	E	H	H	F	G	G	V	I	Y
Secondary structure
SS confidence
Disorder									?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.	.	.	.	.	1180
Sequence	L	F	L	R	G	V	D	K	E	H	P	Q	Q	G	I	Y	T	T	R	P	N	A	G	L	I	A	L	M	D	E	M	F	A	G	M	T	L	E	E	A
Secondary structure
SS confidence
Disorder								?																										?	?	?	?	?	?	?
Disorder confidence