Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP25772
DateThu Jan 5 11:42:38 GMT 2012
Unique Job ID7a27e3b50d8888f8

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2owoA_
Top template information
PDB header:ligase/dna
Chain: A: PDB Molecule:dna ligase;
PDBTitle: last stop on the road to repair: structure of e.coli dna ligase bound2 to nicked dna-adenylate
Confidence and coverage
Confidence:100.0% Coverage: 95%
532 residues ( 95% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MKVWMAILIGILCWQSSVWAVCPAWSPARAQEEISRLQQQIKQWDDDYWKEGKSEVEDGV
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Disorder  ???










????????


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?


?

?


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   .........70.........80.........90.........100.........110.........120
Sequence  YDQLSARLTQWQRCFGSEPRDVMMPPLNGAVMHPVAHTGVRKMVDKNALSLWMRERSDLW
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???????????????


























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   .........130.........140.........150.........160.........170.........180
Sequence  VQPKVDGVAVTLVYRDGKLNKAISRGNGLKGEDWTQKVSLISAVPQTVSGPLANSTLQGE
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   .........190.........200.........210.........220.........230.........240
Sequence  IFLQREGHIQQQMGGINARAKVAGLMMRQDDSDTLNSLGVFVWAWPDGPQLMSDRLKELA
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???














??

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   .........250.........260.........270.........280.........290.........300
Sequence  TAGFTLTQTYTRAVKNADEVARVRNEWWKAELPFVTDGVVVRAAKEPESRHWLPGQAEWL
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??????
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   .........310.........320.........330.........340.........350.........360
Sequence  VAWKYQPVAQVAEVKAIQFAVGKSGKISVVASLAPVMLDDKKVQRVNIGSVRRWQEWDIA
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   .........370.........380.........390.........400.........410.........420
Sequence  PGDQILVSLAGQGIPRIDDVVWRGAERTKPTPPENRFNSLTCYFASDVCQEQFISRLVWL
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   .........430.........440.........450.........460.........470.........480
Sequence  GAKQVLGLDGIGEAGWRALHQTHRFEHIFSWLLLTPEQLQNTPGIAKSKSAQLWHQFNLA
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   .........490.........500.........510.........520.........530.........540
Sequence  RKQPFTRWVMAMGIPLTRAALNASDERSWSQLLFSTEQFWQQLPGTGSGRARQVIEWKEN
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   .........550.........560
Sequence  AQIKKLGSWLAAQQITGFEP
Secondary structure 







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Disorder 












???????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2owo chain A

3D model

Region: 28 - 560
Aligned: 532
Modelled: 533
Confidence: 100.0%
Identity: 23%
PDB header:ligase/dna
Chain: A: PDB Molecule:dna ligase;
PDBTitle: last stop on the road to repair: structure of e.coli dna ligase bound2 to nicked dna-adenylate

Phyre2

PDB 1v9p chain B

3D model

Region: 25 - 557
Aligned: 532
Modelled: 533
Confidence: 100.0%
Identity: 23%
PDB header:ligase
Chain: B: PDB Molecule:dna ligase;
PDBTitle: crystal structure of nad+-dependent dna ligase

Phyre2

PDB 1dgs chain B

3D model

Region: 25 - 557
Aligned: 529
Modelled: 532
Confidence: 100.0%
Identity: 22%
PDB header:ligase
Chain: B: PDB Molecule:dna ligase;
PDBTitle: crystal structure of nad+-dependent dna ligase from t.2 filiformis

Phyre2

PDB 3pn1 chain A

3D model

Region: 29 - 307
Aligned: 278
Modelled: 279
Confidence: 100.0%
Identity: 25%
PDB header:ligase/ligase inhibitor
Chain: A: PDB Molecule:dna ligase;
PDBTitle: novel bacterial nad+-dependent dna ligase inhibitors with broad2 spectrum potency and antibacterial efficacy in vivo

Phyre2

PDB 1b04 chain A

3D model

Region: 26 - 308
Aligned: 281
Modelled: 283
Confidence: 100.0%
Identity: 25%
Fold: ATP-grasp
Superfamily: DNA ligase/mRNA capping enzyme, catalytic domain
Family: Adenylation domain of NAD+-dependent DNA ligase

Phyre2

PDB 1ta8 chain A

3D model

Region: 25 - 306
Aligned: 280
Modelled: 282
Confidence: 100.0%
Identity: 24%
Fold: ATP-grasp
Superfamily: DNA ligase/mRNA capping enzyme, catalytic domain
Family: Adenylation domain of NAD+-dependent DNA ligase

Phyre2

PDB 3jsl chain A

3D model

Region: 29 - 306
Aligned: 276
Modelled: 278
Confidence: 100.0%
Identity: 26%
PDB header:ligase
Chain: A: PDB Molecule:dna ligase;
PDBTitle: crystal structure of the adenylation domain of nad+-2 dependent dna ligase from staphylococcus aureus

Phyre2

PDB 1v9p chain A domain 3

3D model

Region: 25 - 306
Aligned: 281
Modelled: 282
Confidence: 100.0%
Identity: 25%
Fold: ATP-grasp
Superfamily: DNA ligase/mRNA capping enzyme, catalytic domain
Family: Adenylation domain of NAD+-dependent DNA ligase

Phyre2

PDB 1zau chain A

3D model

Region: 25 - 308
Aligned: 283
Modelled: 284
Confidence: 100.0%
Identity: 23%
PDB header:ligase
Chain: A: PDB Molecule:dna ligase;
PDBTitle: adenylation domain of nad+ dependent dna ligase from2 m.tuberculosis

Phyre2

PDB 1dgs chain A domain 3

3D model

Region: 25 - 306
Aligned: 278
Modelled: 282
Confidence: 100.0%
Identity: 24%
Fold: ATP-grasp
Superfamily: DNA ligase/mRNA capping enzyme, catalytic domain
Family: Adenylation domain of NAD+-dependent DNA ligase

Phyre2

PDB 3bac chain A

3D model

Region: 89 - 312
Aligned: 223
Modelled: 223
Confidence: 100.0%
Identity: 24%
PDB header:ligase
Chain: A: PDB Molecule:dna ligase;
PDBTitle: structural basis for the inhibition of bacterial nad+2 dependent dna ligase

Phyre2

PDB 1dgs chain A domain 1

3D model

Region: 392 - 559
Aligned: 168
Modelled: 168
Confidence: 100.0%
Identity: 15%
Fold: SAM domain-like
Superfamily: RuvA domain 2-like
Family: NAD+-dependent DNA ligase, domain 3

Phyre2

PDB 1dgs chain A domain 2

3D model

Region: 307 - 389
Aligned: 83
Modelled: 83
Confidence: 100.0%
Identity: 28%
Fold: OB-fold
Superfamily: Nucleic acid-binding proteins
Family: DNA ligase/mRNA capping enzyme postcatalytic domain

Phyre2

PDB 1x9n chain A domain 3

3D model

Region: 96 - 308
Aligned: 195
Modelled: 212
Confidence: 99.6%
Identity: 15%
Fold: ATP-grasp
Superfamily: DNA ligase/mRNA capping enzyme, catalytic domain
Family: ATP-dependent DNA ligase catalytic domain

Phyre2

PDB 2a1j chain B domain 1

3D model

Region: 475 - 544
Aligned: 70
Modelled: 70
Confidence: 99.0%
Identity: 14%
Fold: SAM domain-like
Superfamily: RuvA domain 2-like
Family: Hef domain-like

Phyre2

PDB 2hiv chain A

3D model

Region: 90 - 357
Aligned: 247
Modelled: 268
Confidence: 98.9%
Identity: 18%
PDB header:ligase
Chain: A: PDB Molecule:thermostable dna ligase;
PDBTitle: atp-dependent dna ligase from s. solfataricus

Phyre2

PDB 3gde chain A

3D model

Region: 96 - 335
Aligned: 214
Modelled: 237
Confidence: 98.9%
Identity: 20%
PDB header:ligase
Chain: A: PDB Molecule:dna ligase;
PDBTitle: the closed conformation of atp-dependent dna ligase from2 archaeoglobus fulgidus

Phyre2

PDB 2vug chain B

3D model

Region: 115 - 282
Aligned: 142
Modelled: 150
Confidence: 98.8%
Identity: 23%
PDB header:ligase
Chain: B: PDB Molecule:pab1020;
PDBTitle: the structure of an archaeal homodimeric rna ligase

Phyre2

PDB 3l2p chain A

3D model

Region: 96 - 375
Aligned: 252
Modelled: 280
Confidence: 98.8%
Identity: 13%
PDB header:ligase/dna
Chain: A: PDB Molecule:dna ligase 3;
PDBTitle: human dna ligase iii recognizes dna ends by dynamic switching between2 two dna bound states

Phyre2

PDB 1x2i chain A domain 1

3D model

Region: 486 - 541
Aligned: 56
Modelled: 56
Confidence: 98.7%
Identity: 14%
Fold: SAM domain-like
Superfamily: RuvA domain 2-like
Family: Hef domain-like

Phyre2
1

c2owoA_
2

c1v9pB_
3

c1dgsB_
4

c3pn1A_
5

d1b04a_
6

d1ta8a_
7

c3jslA_
8

d1v9pa3
9

c1zauA_
10

d1dgsa3
11

c3bacA_
12

d1dgsa1
13

d1dgsa2
14

d1x9na3
15

d2a1jb1
16

c2hivA_
17

c3gdeA_
18

c2vugB_
19

c3l2pA_
20

d1x2ia1
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2owoA_



100.0 23 PDB header:ligase/dna
Chain: A: PDB Molecule:dna ligase;
PDBTitle: last stop on the road to repair: structure of e.coli dna ligase bound2 to nicked dna-adenylate
2c1v9pB_



100.0 23 PDB header:ligase
Chain: B: PDB Molecule:dna ligase;
PDBTitle: crystal structure of nad+-dependent dna ligase
3c1dgsB_



100.0 22 PDB header:ligase
Chain: B: PDB Molecule:dna ligase;
PDBTitle: crystal structure of nad+-dependent dna ligase from t.2 filiformis
4c3pn1A_



100.0 25 PDB header:ligase/ligase inhibitor
Chain: A: PDB Molecule:dna ligase;
PDBTitle: novel bacterial nad+-dependent dna ligase inhibitors with broad2 spectrum potency and antibacterial efficacy in vivo
5d1b04a_



100.0 25 Fold:ATP-grasp
Superfamily:DNA ligase/mRNA capping enzyme, catalytic domain
Family:Adenylation domain of NAD+-dependent DNA ligase
6d1ta8a_



100.0 24 Fold:ATP-grasp
Superfamily:DNA ligase/mRNA capping enzyme, catalytic domain
Family:Adenylation domain of NAD+-dependent DNA ligase
7c3jslA_



100.0 26 PDB header:ligase
Chain: A: PDB Molecule:dna ligase;
PDBTitle: crystal structure of the adenylation domain of nad+-2 dependent dna ligase from staphylococcus aureus
8d1v9pa3



100.0 25 Fold:ATP-grasp
Superfamily:DNA ligase/mRNA capping enzyme, catalytic domain
Family:Adenylation domain of NAD+-dependent DNA ligase
9c1zauA_



100.0 23 PDB header:ligase
Chain: A: PDB Molecule:dna ligase;
PDBTitle: adenylation domain of nad+ dependent dna ligase from2 m.tuberculosis
10d1dgsa3



100.0 24 Fold:ATP-grasp
Superfamily:DNA ligase/mRNA capping enzyme, catalytic domain
Family:Adenylation domain of NAD+-dependent DNA ligase
11c3bacA_



100.0 24 PDB header:ligase
Chain: A: PDB Molecule:dna ligase;
PDBTitle: structural basis for the inhibition of bacterial nad+2 dependent dna ligase
12d1dgsa1



100.0 15 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:NAD+-dependent DNA ligase, domain 3
13d1dgsa2



100.0 28 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:DNA ligase/mRNA capping enzyme postcatalytic domain
14d1x9na3



99.6 15 Fold:ATP-grasp
Superfamily:DNA ligase/mRNA capping enzyme, catalytic domain
Family:ATP-dependent DNA ligase catalytic domain
15d2a1jb1



99.0 14 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:Hef domain-like
16c2hivA_



98.9 18 PDB header:ligase
Chain: A: PDB Molecule:thermostable dna ligase;
PDBTitle: atp-dependent dna ligase from s. solfataricus
17c3gdeA_



98.9 20 PDB header:ligase
Chain: A: PDB Molecule:dna ligase;
PDBTitle: the closed conformation of atp-dependent dna ligase from2 archaeoglobus fulgidus
18c2vugB_



98.8 23 PDB header:ligase
Chain: B: PDB Molecule:pab1020;
PDBTitle: the structure of an archaeal homodimeric rna ligase
19c3l2pA_



98.8 13 PDB header:ligase/dna
Chain: A: PDB Molecule:dna ligase 3;
PDBTitle: human dna ligase iii recognizes dna ends by dynamic switching between2 two dna bound states
20d1x2ia1



98.7 14 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:Hef domain-like
21c2cfmA_



not modelled 98.6 14 PDB header:ligase
Chain: A: PDB Molecule:thermostable dna ligase;
PDBTitle: atp-dependent dna ligase from pyrococcus furiosus
22c1x9nA_



not modelled 98.6 16 PDB header:ligase/dna
Chain: A: PDB Molecule:dna ligase i;
PDBTitle: crystal structure of human dna ligase i bound to 5'-adenylated, nicked2 dna
23d2bgwa1



not modelled 98.6 16 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:Hef domain-like
24c3qwuA_



not modelled 98.3 13 PDB header:ligase
Chain: A: PDB Molecule:dna ligase;
PDBTitle: putative atp-dependent dna ligase from aquifex aeolicus.
25c1p8lA_



not modelled 98.3 15 PDB header:ligase
Chain: A: PDB Molecule:pbcv-1 dna ligase;
PDBTitle: new crystal structure of chlorella virus dna ligase-adenylate
26c1a0iA_



not modelled 98.1 16 PDB header:ligase
Chain: A: PDB Molecule:dna ligase;
PDBTitle: atp-dependent dna ligase from bacteriophage t7 complex with2 atp
27d1kfta_



not modelled 98.1 15 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:Excinuclease UvrC C-terminal domain
28c1kftA_



not modelled 98.1 15 PDB header:dna binding protein
Chain: A: PDB Molecule:excinuclease abc subunit c;
PDBTitle: solution structure of the c-terminal domain of uvrc from e-2 coli
29d1fvia2



not modelled 98.0 14 Fold:ATP-grasp
Superfamily:DNA ligase/mRNA capping enzyme, catalytic domain
Family:ATP-dependent DNA ligase catalytic domain
30c1vs0A_



not modelled 97.8 22 PDB header:ligase
Chain: A: PDB Molecule:putative dna ligase-like protein rv0938/mt0965;
PDBTitle: crystal structure of the ligase domain from m. tuberculosis ligd at2 2.4a
31c2nrzB_



not modelled 97.7 16 PDB header:hydrolase
Chain: B: PDB Molecule:uvrabc system protein c;
PDBTitle: crystal structure of the c-terminal half of uvrc bound to2 its catalytic divalent cation
32c3c1zA_



not modelled 97.7 15 PDB header:dna binding protein
Chain: A: PDB Molecule:dna integrity scanning protein disa;
PDBTitle: structure of the ligand-free form of a bacterial dna damage2 sensor protein
33d2i1qa1



not modelled 97.6 17 Fold:SAM domain-like
Superfamily:Rad51 N-terminal domain-like
Family:DNA repair protein Rad51, N-terminal domain
34d1szpa1



not modelled 97.6 19 Fold:SAM domain-like
Superfamily:Rad51 N-terminal domain-like
Family:DNA repair protein Rad51, N-terminal domain
35c2bhnD_



not modelled 97.6 18 PDB header:hydrolase
Chain: D: PDB Molecule:xpf endonuclease;
PDBTitle: xpf from aeropyrum pernix
36d1a0ia2



not modelled 97.6 14 Fold:ATP-grasp
Superfamily:DNA ligase/mRNA capping enzyme, catalytic domain
Family:ATP-dependent DNA ligase catalytic domain
37d1pzna1



not modelled 97.5 17 Fold:SAM domain-like
Superfamily:Rad51 N-terminal domain-like
Family:DNA repair protein Rad51, N-terminal domain
38c1b22A_



not modelled 97.5 20 PDB header:dna binding protein
Chain: A: PDB Molecule:dna repair protein rad51;
PDBTitle: rad51 (n-terminal domain)
39d1b22a_



not modelled 97.5 20 Fold:SAM domain-like
Superfamily:Rad51 N-terminal domain-like
Family:DNA repair protein Rad51, N-terminal domain
40d1ckma2



not modelled 97.3 14 Fold:ATP-grasp
Superfamily:DNA ligase/mRNA capping enzyme, catalytic domain
Family:mRNA capping enzyme
41d2aq0a1



not modelled 97.3 10 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:Hef domain-like
42c3kyhC_



not modelled 97.1 19 PDB header:protein binding
Chain: C: PDB Molecule:mrna-capping enzyme subunit alpha;
PDBTitle: saccharomyces cerevisiae cet1-ceg1 capping apparatus
43c1p16A_



not modelled 96.9 17 PDB header:transferase
Chain: A: PDB Molecule:mrna capping enzyme alpha subunit;
PDBTitle: structure of an mrna capping enzyme bound to the2 phosphorylated carboxyl-terminal domain of rna polymerase3 ii
44c1cknA_



not modelled 96.9 16 PDB header:capping enzyme
Chain: A: PDB Molecule:mrna capping enzyme;
PDBTitle: structure of guanylylated mrna capping enzyme complexed2 with gtp
45d1szpb1



not modelled 96.8 19 Fold:SAM domain-like
Superfamily:Rad51 N-terminal domain-like
Family:DNA repair protein Rad51, N-terminal domain
46c3s24F_



not modelled 96.5 16 PDB header:hydrolase, transferase
Chain: F: PDB Molecule:mrna-capping enzyme;
PDBTitle: crystal structure of human mrna guanylyltransferase
47d1p16a2



not modelled 96.5 18 Fold:ATP-grasp
Superfamily:DNA ligase/mRNA capping enzyme, catalytic domain
Family:mRNA capping enzyme
48c2w9mB_



not modelled 96.5 16 PDB header:dna replication
Chain: B: PDB Molecule:polymerase x;
PDBTitle: structure of family x dna polymerase from deinococcus2 radiodurans
49c2csdB_



not modelled 96.1 16 PDB header:isomerase
Chain: B: PDB Molecule:topoisomerase v;
PDBTitle: crystal structure of topoisomerase v (61 kda fragment)
50d1pu6a_



not modelled 96.0 18 Fold:DNA-glycosylase
Superfamily:DNA-glycosylase
Family:3-Methyladenine DNA glycosylase III (MagIII)
51d1doqa_



not modelled 95.6 20 Fold:SAM domain-like
Superfamily:C-terminal domain of RNA polymerase alpha subunit
Family:C-terminal domain of RNA polymerase alpha subunit
52d1lb2b_



not modelled 95.6 14 Fold:SAM domain-like
Superfamily:C-terminal domain of RNA polymerase alpha subunit
Family:C-terminal domain of RNA polymerase alpha subunit
53d1z3eb1



not modelled 95.3 6 Fold:SAM domain-like
Superfamily:C-terminal domain of RNA polymerase alpha subunit
Family:C-terminal domain of RNA polymerase alpha subunit
54d1cooa_



not modelled 95.2 14 Fold:SAM domain-like
Superfamily:C-terminal domain of RNA polymerase alpha subunit
Family:C-terminal domain of RNA polymerase alpha subunit
55d2p6ra2



not modelled 94.8 10 Fold:Sec63 N-terminal domain-like
Superfamily:Sec63 N-terminal domain-like
Family:Achaeal helicase C-terminal domain
56c3f10A_



not modelled 94.8 14 PDB header:hydrolase, lyase
Chain: A: PDB Molecule:8-oxoguanine-dna-glycosylase;
PDBTitle: crystal structure of clostridium acetobutylicum 8-2 oxoguanine dna glycosylase in complex with 8-oxoguanosine
57c2h5xA_



not modelled 94.8 13 PDB header:dna binding protein
Chain: A: PDB Molecule:holliday junction atp-dependent dna helicase ruva;
PDBTitle: ruva from mycobacterium tuberculosis
58d1cuka2



not modelled 94.4 15 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:DNA helicase RuvA subunit, middle domain
59c2hvsA_



not modelled 94.3 15 PDB header:ligase/dna/rna
Chain: A: PDB Molecule:t4 rna ligase 2;
PDBTitle: structure of t4 rna ligase 2 with nicked 5'-adenylated2 nucleic acid duplex containing a 2'-deoxyribonucleotide at3 the nick
60c1ixrA_



not modelled 94.2 13 PDB header:hydrolase
Chain: A: PDB Molecule:holliday junction dna helicase ruva;
PDBTitle: ruva-ruvb complex
61c1s5lu_



not modelled 93.4 11 PDB header:photosynthesis
Chain: U: PDB Molecule:photosystem ii 12 kda extrinsic protein;
PDBTitle: architecture of the photosynthetic oxygen evolving center
62d1ixra1



not modelled 93.3 13 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:DNA helicase RuvA subunit, middle domain
63d3bzka1



not modelled 93.2 12 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:Tex HhH-containing domain-like
64d1s68a_



not modelled 93.0 15 Fold:ATP-grasp
Superfamily:DNA ligase/mRNA capping enzyme, catalytic domain
Family:RNA ligase
65d1keaa_



not modelled 92.9 14 Fold:DNA-glycosylase
Superfamily:DNA-glycosylase
Family:Mismatch glycosylase
66c1rrqA_



not modelled 92.6 13 PDB header:hydrolase/dna
Chain: A: PDB Molecule:muty;
PDBTitle: muty adenine glycosylase in complex with dna containing an2 a:oxog pair
67c1d8lA_



not modelled 92.5 17 PDB header:gene regulation
Chain: A: PDB Molecule:protein (holliday junction dna helicase ruva);
PDBTitle: e. coli holliday junction binding protein ruva nh2 region2 lacking domain iii
68d2abka_



not modelled 92.4 14 Fold:DNA-glycosylase
Superfamily:DNA-glycosylase
Family:Endonuclease III
69d2axtu1



not modelled 92.2 11 Fold:SAM domain-like
Superfamily:PsbU/PolX domain-like
Family:PsbU-like
70c2ihmA_



not modelled 92.2 11 PDB header:transferase/dna
Chain: A: PDB Molecule:dna polymerase mu;
PDBTitle: polymerase mu in ternary complex with gapped 11mer dna2 duplex and bound incoming nucleotide
71c1ko9A_



not modelled 91.6 15 PDB header:hydrolase
Chain: A: PDB Molecule:8-oxoguanine dna glycosylase;
PDBTitle: native structure of the human 8-oxoguanine dna glycosylase2 hogg1
72d2noha1



not modelled 91.4 19 Fold:DNA-glycosylase
Superfamily:DNA-glycosylase
Family:DNA repair glycosylase, 2 C-terminal domains
73d2edua1



not modelled 91.1 17 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:ComEA-like
74c1kdhA_



not modelled 90.5 9 PDB header:transferase/dna
Chain: A: PDB Molecule:terminal deoxynucleotidyltransferase short
PDBTitle: binary complex of murine terminal deoxynucleotidyl2 transferase with a primer single stranded dna
75c2p6uA_



not modelled 90.2 11 PDB header:dna binding protein
Chain: A: PDB Molecule:afuhel308 helicase;
PDBTitle: apo structure of the hel308 superfamily 2 helicase
76c1hjpA_



not modelled 90.2 17 PDB header:dna recombination
Chain: A: PDB Molecule:ruva;
PDBTitle: holliday junction binding protein ruva from e. coli
77c2yg8B_



not modelled 90.2 22 PDB header:hydrolase
Chain: B: PDB Molecule:dna-3-methyladenine glycosidase ii, putative;
PDBTitle: structure of an unusual 3-methyladenine dna glycosylase ii (2 alka) from deinococcus radiodurans
78c1nomA_



not modelled 90.1 13 PDB header:nucleotidyltransferase
Chain: A: PDB Molecule:dna polymerase beta;
PDBTitle: dna polymerase beta (pol b) (e.c.2.7.7.7), 31-kd domain; soaked in the2 presence of mncl2 (5 millimolar)
79d1rrqa1



not modelled 89.8 13 Fold:DNA-glycosylase
Superfamily:DNA-glycosylase
Family:Mismatch glycosylase
80d1kg2a_



not modelled 89.7 14 Fold:DNA-glycosylase
Superfamily:DNA-glycosylase
Family:Mismatch glycosylase
81c3s6iA_



not modelled 89.6 13 PDB header:hydrolase/dna
Chain: A: PDB Molecule:dna-3-methyladenine glycosylase 1;
PDBTitle: schizosaccaromyces pombe 3-methyladenine dna glycosylase (mag1) in2 complex with abasic-dna.
82c1wcnA_



not modelled 89.2 16 PDB header:rna-binding protein
Chain: A: PDB Molecule:transcription elongation protein nusa;
PDBTitle: nmr structure of the carboxyterminal domains of escherichia2 coli nusa
83c8iczA_



not modelled 89.1 7 PDB header:transferase/dna
Chain: A: PDB Molecule:protein (dna polymerase beta (e.c.2.7.7.7));
PDBTitle: dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with2 seven base pairs of dna; soaked in the presence of of datp3 (1 millimolar), mncl2 (5 millimolar), and lithium sulfate4 (75 millimolar)
84d1bvsa2



not modelled 89.0 13 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:DNA helicase RuvA subunit, middle domain
85d2q0zx1



not modelled 88.5 12 Fold:Sec63 N-terminal domain-like
Superfamily:Sec63 N-terminal domain-like
Family:Sec63 N-terminal domain
86d1u9la_



not modelled 88.4 10 Fold:SAM domain-like
Superfamily:Rad51 N-terminal domain-like
Family:NusA extra C-terminal domains
87d2duya1



not modelled 88.2 30 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:ComEA-like
88c2va8A_



not modelled 87.9 13 PDB header:hydrolase
Chain: A: PDB Molecule:ski2-type helicase;
PDBTitle: dna repair helicase hel308
89d1orna_



not modelled 87.5 14 Fold:DNA-glycosylase
Superfamily:DNA-glycosylase
Family:Endonuclease III
90d1ngna_



not modelled 86.3 13 Fold:DNA-glycosylase
Superfamily:DNA-glycosylase
Family:Mismatch glycosylase
91c2bcuA_



not modelled 85.9 11 PDB header:transferase, lyase/dna
Chain: A: PDB Molecule:dna polymerase lambda;
PDBTitle: dna polymerase lambda in complex with a dna duplex2 containing an unpaired damp and a t:t mismatch
92d2a1ja1



not modelled 85.3 11 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:Hef domain-like
93c3n5nX_



not modelled 85.0 21 PDB header:hydrolase
Chain: X: PDB Molecule:a/g-specific adenine dna glycosylase;
PDBTitle: crystal structure analysis of the catalytic domain and interdomain2 connector of human muty homologue
94c1yqmA_



not modelled 84.9 19 PDB header:hydrolase/dna
Chain: A: PDB Molecule:n-glycosylase/dna lyase;
PDBTitle: catalytically inactive human 8-oxoguanine glycosylase2 crosslinked to 7-deazaguanine containing dna
95c3gqcB_



not modelled 84.5 17 PDB header:transferase/dna
Chain: B: PDB Molecule:dna repair protein rev1;
PDBTitle: structure of human rev1-dna-dntp ternary complex
96d1mpga1



not modelled 84.4 22 Fold:DNA-glycosylase
Superfamily:DNA-glycosylase
Family:DNA repair glycosylase, 2 C-terminal domains
97c1t3nB_



not modelled 83.8 15 PDB header:replication/dna
Chain: B: PDB Molecule:polymerase (dna directed) iota;
PDBTitle: structure of the catalytic core of dna polymerase iota in2 complex with dna and dttp
98d1jx4a2



not modelled 83.3 20 Fold:DNA/RNA polymerases
Superfamily:DNA/RNA polymerases
Family:Lesion bypass DNA polymerase (Y-family), catalytic domain
99c2ziuA_



not modelled 81.9 15 PDB header:hydrolase
Chain: A: PDB Molecule:mus81 protein;
PDBTitle: crystal structure of the mus81-eme1 complex
100c3n0uB_



not modelled 81.4 11 PDB header:hydrolase, lyase
Chain: B: PDB Molecule:probable n-glycosylase/dna lyase;
PDBTitle: crystal structure of tm1821, the 8-oxoguanine dna glycosylase of2 thermotoga maritima
101c1t4gA_



not modelled 80.8 17 PDB header:recombination
Chain: A: PDB Molecule:dna repair and recombination protein rada;
PDBTitle: atpase in complex with amp-pnp
102d2bcqa1



not modelled 80.8 31 Fold:SAM domain-like
Superfamily:DNA polymerase beta, N-terminal domain-like
Family:DNA polymerase beta, N-terminal domain-like
103d1k1sa2



not modelled 80.4 22 Fold:DNA/RNA polymerases
Superfamily:DNA/RNA polymerases
Family:Lesion bypass DNA polymerase (Y-family), catalytic domain
104c1k1qA_



not modelled 80.4 22 PDB header:transcription
Chain: A: PDB Molecule:dbh protein;
PDBTitle: crystal structure of a dinb family error prone dna2 polymerase from sulfolobus solfataricus
105d2fmpa1



not modelled 80.2 25 Fold:SAM domain-like
Superfamily:DNA polymerase beta, N-terminal domain-like
Family:DNA polymerase beta, N-terminal domain-like
106c3senD_



not modelled 79.7 12 PDB header:signaling protein
Chain: D: PDB Molecule:caskin-1;
PDBTitle: structure of caskin1 tandem sams
107d1nzpa_



not modelled 79.1 31 Fold:SAM domain-like
Superfamily:DNA polymerase beta, N-terminal domain-like
Family:DNA polymerase beta, N-terminal domain-like
108c2c5uA_



not modelled 79.1 18 PDB header:ligase
Chain: A: PDB Molecule:rna ligase;
PDBTitle: t4 rna ligase (rnl1) crystal structure
109d1t94a2



not modelled 78.8 13 Fold:DNA/RNA polymerases
Superfamily:DNA/RNA polymerases
Family:Lesion bypass DNA polymerase (Y-family), catalytic domain
110d1coka_



not modelled 78.1 15 Fold:SAM domain-like
Superfamily:SAM/Pointed domain
Family:SAM (sterile alpha motif) domain
111c2fllA_



not modelled 77.7 15 PDB header:replication/dna
Chain: A: PDB Molecule:dna polymerase iota;
PDBTitle: ternary complex of human dna polymerase iota with dna and dttp
112c1szpC_



not modelled 75.4 18 PDB header:dna binding protein
Chain: C: PDB Molecule:dna repair protein rad51;
PDBTitle: a crystal structure of the rad51 filament
113c1mpgB_



not modelled 75.2 20 PDB header:hydrolase
Chain: B: PDB Molecule:3-methyladenine dna glycosylase ii;
PDBTitle: 3-methyladenine dna glycosylase ii from escherichia coli
114d2bcqa2



not modelled 74.9 17 Fold:SAM domain-like
Superfamily:PsbU/PolX domain-like
Family:DNA polymerase beta-like, second domain
115d1dk2a_



not modelled 74.5 23 Fold:SAM domain-like
Superfamily:DNA polymerase beta, N-terminal domain-like
Family:DNA polymerase beta, N-terminal domain-like
116d2fmpa2



not modelled 74.4 15 Fold:SAM domain-like
Superfamily:PsbU/PolX domain-like
Family:DNA polymerase beta-like, second domain
117d1jmsa1



not modelled 74.0 9 Fold:SAM domain-like
Superfamily:DNA polymerase beta, N-terminal domain-like
Family:DNA polymerase beta, N-terminal domain-like
118c2kp7A_



not modelled 73.9 16 PDB header:hydrolase
Chain: A: PDB Molecule:crossover junction endonuclease mus81;
PDBTitle: solution nmr structure of the mus81 n-terminal hhh.2 northeast structural genomics consortium target mmt1a
119c1s97D_



not modelled 73.5 19 PDB header:transferase/dna
Chain: D: PDB Molecule:dna polymerase iv;
PDBTitle: dpo4 with gt mismatch
120c1vddC_



not modelled 73.4 19 PDB header:recombination
Chain: C: PDB Molecule:recombination protein recr;
PDBTitle: crystal structure of recombinational repair protein recr

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0