Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP15042
DateThu Jan 5 11:34:23 GMT 2012
Unique Job ID1a930323ea46bc05

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2owoA_
Top template information
PDB header:ligase/dna
Chain: A: PDB Molecule:dna ligase;
PDBTitle: last stop on the road to repair: structure of e.coli dna ligase bound2 to nicked dna-adenylate
Confidence and coverage
Confidence:100.0% Coverage: 87%
586 residues ( 87% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
667 residues ( 99%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MESIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRELETKHPELITPDSPTQ
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Disorder  ?





















?


?

?

























??
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   .........70.........80.........90.........100.........110.........120
Sequence  RVGAAPLAAFSQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKNNEKVTWCCELKLDGLA
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Disorder  ?


????



















































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   .........130.........140.........150.........160.........170.........180
Sequence  VSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLHGENIPARLEVRGEVFLPQAG
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   .........190.........200.........210.........220.........230.........240
Sequence  FEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGVLEGGELPDTHL
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Disorder 









?????












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   .........250.........260.........270.........280.........290.........300
Sequence  GRLLQFKKWGLPVSDRVTLCESAEEVLAFYHKVEEDRPTLGFDIDGVVIKVNSLAQQEQL
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?





















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   .........310.........320.........330.........340.........350.........360
Sequence  GFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVHVAGVLVSNATLHN
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Disorder  ???
























































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   .........370.........380.........390.........400.........410.........420
Sequence  ADEIERLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEDTREVVFPTHCPVCGSDVERVEG
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?
?
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   .........430.........440.........450.........460.........470.........480
Sequence  EAVARCTGGLICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEKEYVHTPADLFKLTAG
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?















































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   .........490.........500.........510.........520.........530.........540
Sequence  KLTGLERMGPKSAQNVVNALEKAKETTFARFLYALGIREVGEATAAGLAAYFGTLEALEA
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?














??


































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   .........550.........560.........570.........580.........590.........600
Sequence  ASIEELQKVPDVGIVVASHVHNFFAEESNRNVISELLAEGVHWPAPIVINAEEIDSPFAG
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?






??????
??????
????




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   .........610.........620.........630.........640.........650.........660
Sequence  KTVVLTGSLSQMSRDDAKARLVELGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVI
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   .........670.
Sequence  DEAEMLRLLGS
Secondary structure 

SS confidence 










Disorder 








??
Disorder confidence 










 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2owo chain A

3D model

Region: 1 - 586
Aligned: 586
Modelled: 586
Confidence: 100.0%
Identity: 100%
PDB header:ligase/dna
Chain: A: PDB Molecule:dna ligase;
PDBTitle: last stop on the road to repair: structure of e.coli dna ligase bound2 to nicked dna-adenylate

Phyre2

PDB 1v9p chain B

3D model

Region: 2 - 586
Aligned: 580
Modelled: 585
Confidence: 100.0%
Identity: 46%
PDB header:ligase
Chain: B: PDB Molecule:dna ligase;
PDBTitle: crystal structure of nad+-dependent dna ligase

Phyre2

PDB 1dgs chain B

3D model

Region: 2 - 586
Aligned: 575
Modelled: 584
Confidence: 100.0%
Identity: 45%
PDB header:ligase
Chain: B: PDB Molecule:dna ligase;
PDBTitle: crystal structure of nad+-dependent dna ligase from t.2 filiformis

Phyre2

PDB 3pn1 chain A

3D model

Region: 1 - 317
Aligned: 317
Modelled: 317
Confidence: 100.0%
Identity: 62%
PDB header:ligase/ligase inhibitor
Chain: A: PDB Molecule:dna ligase;
PDBTitle: novel bacterial nad+-dependent dna ligase inhibitors with broad2 spectrum potency and antibacterial efficacy in vivo

Phyre2

PDB 1ta8 chain A

3D model

Region: 1 - 316
Aligned: 310
Modelled: 316
Confidence: 100.0%
Identity: 47%
Fold: ATP-grasp
Superfamily: DNA ligase/mRNA capping enzyme, catalytic domain
Family: Adenylation domain of NAD+-dependent DNA ligase

Phyre2

PDB 3jsl chain A

3D model

Region: 3 - 316
Aligned: 307
Modelled: 314
Confidence: 100.0%
Identity: 45%
PDB header:ligase
Chain: A: PDB Molecule:dna ligase;
PDBTitle: crystal structure of the adenylation domain of nad+-2 dependent dna ligase from staphylococcus aureus

Phyre2

PDB 1b04 chain A

3D model

Region: 2 - 318
Aligned: 308
Modelled: 314
Confidence: 100.0%
Identity: 50%
Fold: ATP-grasp
Superfamily: DNA ligase/mRNA capping enzyme, catalytic domain
Family: Adenylation domain of NAD+-dependent DNA ligase

Phyre2

PDB 1v9p chain A domain 3

3D model

Region: 2 - 316
Aligned: 313
Modelled: 315
Confidence: 100.0%
Identity: 48%
Fold: ATP-grasp
Superfamily: DNA ligase/mRNA capping enzyme, catalytic domain
Family: Adenylation domain of NAD+-dependent DNA ligase

Phyre2

PDB 1zau chain A

3D model

Region: 2 - 318
Aligned: 314
Modelled: 317
Confidence: 100.0%
Identity: 45%
PDB header:ligase
Chain: A: PDB Molecule:dna ligase;
PDBTitle: adenylation domain of nad+ dependent dna ligase from2 m.tuberculosis

Phyre2

PDB 1dgs chain A domain 3

3D model

Region: 2 - 316
Aligned: 308
Modelled: 315
Confidence: 100.0%
Identity: 46%
Fold: ATP-grasp
Superfamily: DNA ligase/mRNA capping enzyme, catalytic domain
Family: Adenylation domain of NAD+-dependent DNA ligase

Phyre2

PDB 3bac chain A

3D model

Region: 69 - 322
Aligned: 254
Modelled: 254
Confidence: 100.0%
Identity: 62%
PDB header:ligase
Chain: A: PDB Molecule:dna ligase;
PDBTitle: structural basis for the inhibition of bacterial nad+2 dependent dna ligase

Phyre2

PDB 1dgs chain A domain 1

3D model

Region: 403 - 586
Aligned: 181
Modelled: 184
Confidence: 100.0%
Identity: 40%
Fold: SAM domain-like
Superfamily: RuvA domain 2-like
Family: NAD+-dependent DNA ligase, domain 3

Phyre2

PDB 1dgs chain A domain 2

3D model

Region: 317 - 402
Aligned: 86
Modelled: 86
Confidence: 100.0%
Identity: 50%
Fold: OB-fold
Superfamily: Nucleic acid-binding proteins
Family: DNA ligase/mRNA capping enzyme postcatalytic domain

Phyre2

PDB 1x9n chain A domain 3

3D model

Region: 78 - 318
Aligned: 201
Modelled: 240
Confidence: 99.7%
Identity: 18%
Fold: ATP-grasp
Superfamily: DNA ligase/mRNA capping enzyme, catalytic domain
Family: ATP-dependent DNA ligase catalytic domain

Phyre2

PDB 2ebu chain A

3D model

Region: 589 - 669
Aligned: 81
Modelled: 81
Confidence: 99.7%
Identity: 38%
PDB header:replication
Chain: A: PDB Molecule:replication factor c subunit 1;
PDBTitle: solution structure of the brct domain from human2 replication factor c large subunit 1

Phyre2

PDB 1l7b chain A

3D model

Region: 592 - 669
Aligned: 77
Modelled: 78
Confidence: 99.6%
Identity: 48%
Fold: BRCT domain
Superfamily: BRCT domain
Family: DNA ligase

Phyre2

PDB 2cok chain A

3D model

Region: 589 - 671
Aligned: 82
Modelled: 83
Confidence: 99.3%
Identity: 24%
PDB header:transferase
Chain: A: PDB Molecule:poly [adp-ribose] polymerase-1;
PDBTitle: solution structure of brct domain of poly(adp-ribose)2 polymerase-1

Phyre2

PDB 2a1j chain B domain 1

3D model

Region: 498 - 567
Aligned: 70
Modelled: 70
Confidence: 99.2%
Identity: 30%
Fold: SAM domain-like
Superfamily: RuvA domain 2-like
Family: Hef domain-like

Phyre2

PDB 3gde chain A

3D model

Region: 78 - 345
Aligned: 220
Modelled: 247
Confidence: 99.2%
Identity: 23%
PDB header:ligase
Chain: A: PDB Molecule:dna ligase;
PDBTitle: the closed conformation of atp-dependent dna ligase from2 archaeoglobus fulgidus

Phyre2

PDB 2hiv chain A

3D model

Region: 78 - 367
Aligned: 239
Modelled: 254
Confidence: 99.2%
Identity: 19%
PDB header:ligase
Chain: A: PDB Molecule:thermostable dna ligase;
PDBTitle: atp-dependent dna ligase from s. solfataricus

Phyre2
1

c2owoA_
2

c1v9pB_
3

c1dgsB_
4

c3pn1A_
5

d1ta8a_
6

c3jslA_
7

d1b04a_
8

d1v9pa3
9

c1zauA_
10

d1dgsa3
11

c3bacA_
12

d1dgsa1
13

d1dgsa2
14

d1x9na3
15

c2ebuA_
16

d1l7ba_
17

c2cokA_
18

d2a1jb1
19

c3gdeA_
20

c2hivA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2owoA_



100.0 100 PDB header:ligase/dna
Chain: A: PDB Molecule:dna ligase;
PDBTitle: last stop on the road to repair: structure of e.coli dna ligase bound2 to nicked dna-adenylate
2c1v9pB_



100.0 46 PDB header:ligase
Chain: B: PDB Molecule:dna ligase;
PDBTitle: crystal structure of nad+-dependent dna ligase
3c1dgsB_



100.0 45 PDB header:ligase
Chain: B: PDB Molecule:dna ligase;
PDBTitle: crystal structure of nad+-dependent dna ligase from t.2 filiformis
4c3pn1A_



100.0 62 PDB header:ligase/ligase inhibitor
Chain: A: PDB Molecule:dna ligase;
PDBTitle: novel bacterial nad+-dependent dna ligase inhibitors with broad2 spectrum potency and antibacterial efficacy in vivo
5d1ta8a_



100.0 47 Fold:ATP-grasp
Superfamily:DNA ligase/mRNA capping enzyme, catalytic domain
Family:Adenylation domain of NAD+-dependent DNA ligase
6c3jslA_



100.0 45 PDB header:ligase
Chain: A: PDB Molecule:dna ligase;
PDBTitle: crystal structure of the adenylation domain of nad+-2 dependent dna ligase from staphylococcus aureus
7d1b04a_



100.0 50 Fold:ATP-grasp
Superfamily:DNA ligase/mRNA capping enzyme, catalytic domain
Family:Adenylation domain of NAD+-dependent DNA ligase
8d1v9pa3



100.0 48 Fold:ATP-grasp
Superfamily:DNA ligase/mRNA capping enzyme, catalytic domain
Family:Adenylation domain of NAD+-dependent DNA ligase
9c1zauA_



100.0 45 PDB header:ligase
Chain: A: PDB Molecule:dna ligase;
PDBTitle: adenylation domain of nad+ dependent dna ligase from2 m.tuberculosis
10d1dgsa3



100.0 46 Fold:ATP-grasp
Superfamily:DNA ligase/mRNA capping enzyme, catalytic domain
Family:Adenylation domain of NAD+-dependent DNA ligase
11c3bacA_



100.0 62 PDB header:ligase
Chain: A: PDB Molecule:dna ligase;
PDBTitle: structural basis for the inhibition of bacterial nad+2 dependent dna ligase
12d1dgsa1



100.0 40 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:NAD+-dependent DNA ligase, domain 3
13d1dgsa2



100.0 50 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:DNA ligase/mRNA capping enzyme postcatalytic domain
14d1x9na3



99.7 18 Fold:ATP-grasp
Superfamily:DNA ligase/mRNA capping enzyme, catalytic domain
Family:ATP-dependent DNA ligase catalytic domain
15c2ebuA_



99.7 38 PDB header:replication
Chain: A: PDB Molecule:replication factor c subunit 1;
PDBTitle: solution structure of the brct domain from human2 replication factor c large subunit 1
16d1l7ba_



99.6 48 Fold:BRCT domain
Superfamily:BRCT domain
Family:DNA ligase
17c2cokA_



99.3 24 PDB header:transferase
Chain: A: PDB Molecule:poly [adp-ribose] polymerase-1;
PDBTitle: solution structure of brct domain of poly(adp-ribose)2 polymerase-1
18d2a1jb1



99.2 30 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:Hef domain-like
19c3gdeA_



99.2 23 PDB header:ligase
Chain: A: PDB Molecule:dna ligase;
PDBTitle: the closed conformation of atp-dependent dna ligase from2 archaeoglobus fulgidus
20c2hivA_



99.2 19 PDB header:ligase
Chain: A: PDB Molecule:thermostable dna ligase;
PDBTitle: atp-dependent dna ligase from s. solfataricus
21c3l2pA_



not modelled 99.0 17 PDB header:ligase/dna
Chain: A: PDB Molecule:dna ligase 3;
PDBTitle: human dna ligase iii recognizes dna ends by dynamic switching between2 two dna bound states
22d1x2ia1



not modelled 99.0 27 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:Hef domain-like
23d2bgwa1



not modelled 98.9 29 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:Hef domain-like
24c2cfmA_



not modelled 98.9 20 PDB header:ligase
Chain: A: PDB Molecule:thermostable dna ligase;
PDBTitle: atp-dependent dna ligase from pyrococcus furiosus
25c2vugB_



not modelled 98.9 19 PDB header:ligase
Chain: B: PDB Molecule:pab1020;
PDBTitle: the structure of an archaeal homodimeric rna ligase
26c1x9nA_



not modelled 98.8 19 PDB header:ligase/dna
Chain: A: PDB Molecule:dna ligase i;
PDBTitle: crystal structure of human dna ligase i bound to 5'-adenylated, nicked2 dna
27c2d8mA_



not modelled 98.7 24 PDB header:dna binding protein
Chain: A: PDB Molecule:dna-repair protein xrcc1;
PDBTitle: solution structure of the first brct domain of dna-repair2 protein xrcc1
28c1kftA_



not modelled 98.6 32 PDB header:dna binding protein
Chain: A: PDB Molecule:excinuclease abc subunit c;
PDBTitle: solution structure of the c-terminal domain of uvrc from e-2 coli
29d1kfta_



not modelled 98.6 32 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:Excinuclease UvrC C-terminal domain
30c3ef0A_



not modelled 98.6 21 PDB header:hydrolase
Chain: A: PDB Molecule:rna polymerase ii subunit a c-terminal domain
PDBTitle: the structure of fcp1, an essential rna polymerase ii ctd2 phosphatase
31c3qwuA_



not modelled 98.5 18 PDB header:ligase
Chain: A: PDB Molecule:dna ligase;
PDBTitle: putative atp-dependent dna ligase from aquifex aeolicus.
32c3l3eA_



not modelled 98.5 19 PDB header:cell cycle
Chain: A: PDB Molecule:dna topoisomerase 2-binding protein 1;
PDBTitle: crystal structure of the sixth brct domain of human topbp1
33c2xnkA_



not modelled 98.5 17 PDB header:isomerase
Chain: A: PDB Molecule:dna topoisomerase 2-binding protein 1;
PDBTitle: structure and function of the rad9-binding region of the dna damage2 checkpoint adaptor topbp1
34d1fvia2



not modelled 98.4 16 Fold:ATP-grasp
Superfamily:DNA ligase/mRNA capping enzyme, catalytic domain
Family:ATP-dependent DNA ligase catalytic domain
35c1p8lA_



not modelled 98.4 15 PDB header:ligase
Chain: A: PDB Molecule:pbcv-1 dna ligase;
PDBTitle: new crystal structure of chlorella virus dna ligase-adenylate
36c2couA_



not modelled 98.4 11 PDB header:cell cycle
Chain: A: PDB Molecule:ect2 protein;
PDBTitle: solution structure of the second brct domain of epithelial2 cell transforming 2
37c2nrzB_



not modelled 98.4 27 PDB header:hydrolase
Chain: B: PDB Molecule:uvrabc system protein c;
PDBTitle: crystal structure of the c-terminal half of uvrc bound to2 its catalytic divalent cation
38c3ef1A_



not modelled 98.3 23 PDB header:hydrolase
Chain: A: PDB Molecule:rna polymerase ii subunit a c-terminal domain
PDBTitle: the structure of fcp1, an essential rna polymerase ii ctd2 phosphatase
39c3c1zA_



not modelled 98.3 25 PDB header:dna binding protein
Chain: A: PDB Molecule:dna integrity scanning protein disa;
PDBTitle: structure of the ligand-free form of a bacterial dna damage2 sensor protein
40d1cdza_



not modelled 98.3 14 Fold:BRCT domain
Superfamily:BRCT domain
Family:DNA-repair protein XRCC1
41c2e2wA_



not modelled 98.3 17 PDB header:ligase
Chain: A: PDB Molecule:dna ligase 4;
PDBTitle: solution structure of the first brct domain of human dna2 ligase iv
42d1wf6a_



not modelled 98.2 14 Fold:BRCT domain
Superfamily:BRCT domain
Family:DNA topoisomerase II binding protein 1, TopBP1
43c3ktfB_



not modelled 98.2 19 PDB header:cell cycle
Chain: B: PDB Molecule:microcephalin;
PDBTitle: structure of the n-terminal brct domain of human2 microcephalin (mcph1).
44c2bhnD_



not modelled 98.2 26 PDB header:hydrolase
Chain: D: PDB Molecule:xpf endonuclease;
PDBTitle: xpf from aeropyrum pernix
45c3ii6Y_



not modelled 98.1 19 PDB header:ligase/dna binding protein
Chain: Y: PDB Molecule:dna ligase 4;
PDBTitle: structure of human xrcc4 in complex with the tandem brct2 domains of dna ligaseiv.
46d1kzyc1



not modelled 98.1 14 Fold:BRCT domain
Superfamily:BRCT domain
Family:53BP1
47d2i1qa1



not modelled 98.1 18 Fold:SAM domain-like
Superfamily:Rad51 N-terminal domain-like
Family:DNA repair protein Rad51, N-terminal domain
48d2aq0a1



not modelled 98.1 19 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:Hef domain-like
49d1t15a2



not modelled 98.0 21 Fold:BRCT domain
Superfamily:BRCT domain
Family:BRCT domain
50c1a0iA_



not modelled 98.0 16 PDB header:ligase
Chain: A: PDB Molecule:dna ligase;
PDBTitle: atp-dependent dna ligase from bacteriophage t7 complex with2 atp
51d1a0ia2



not modelled 98.0 16 Fold:ATP-grasp
Superfamily:DNA ligase/mRNA capping enzyme, catalytic domain
Family:ATP-dependent DNA ligase catalytic domain
52c1vs0A_



not modelled 98.0 18 PDB header:ligase
Chain: A: PDB Molecule:putative dna ligase-like protein rv0938/mt0965;
PDBTitle: crystal structure of the ligase domain from m. tuberculosis ligd at2 2.4a
53c1kzyD_



not modelled 97.9 14 PDB header:dna binding protein, protein binding
Chain: D: PDB Molecule:tumor suppressor p53-binding protein 1;
PDBTitle: crystal structure of the 53bp1 brct region complexed to2 tumor suppressor p53
54c2ebwA_



not modelled 97.9 19 PDB header:transferase
Chain: A: PDB Molecule:dna repair protein rev1;
PDBTitle: solution structure of the brct domain from human dna repair2 protein rev1
55d1pzna1



not modelled 97.9 32 Fold:SAM domain-like
Superfamily:Rad51 N-terminal domain-like
Family:DNA repair protein Rad51, N-terminal domain
56c2vxcA_



not modelled 97.8 15 PDB header:cell cycle
Chain: A: PDB Molecule:dna repair protein rhp9;
PDBTitle: structure of the crb2-brct2 domain complex with2 phosphopeptide.
57d1l0ba1



not modelled 97.8 13 Fold:BRCT domain
Superfamily:BRCT domain
Family:BRCT domain
58c3l40A_



not modelled 97.7 19 PDB header:cell cycle
Chain: A: PDB Molecule:brct-containing protein 1;
PDBTitle: crystal structure of s. pombe brc1 brct5-brct6 domains
59d1szpa1



not modelled 97.7 21 Fold:SAM domain-like
Superfamily:Rad51 N-terminal domain-like
Family:DNA repair protein Rad51, N-terminal domain
60c2r1zB_



not modelled 97.6 19 PDB header:antitumor protein
Chain: B: PDB Molecule:brca1-associated ring domain protein 1;
PDBTitle: crystal structure of the bard1 brct repeat
61c3al3A_



not modelled 97.6 18 PDB header:dna binding protein/protein binding
Chain: A: PDB Molecule:dna topoisomerase 2-binding protein 1;
PDBTitle: crystal structure of topbp1 brct7/8-bach1 peptide complex
62c1b22A_



not modelled 97.5 15 PDB header:dna binding protein
Chain: A: PDB Molecule:dna repair protein rad51;
PDBTitle: rad51 (n-terminal domain)
63d1b22a_



not modelled 97.5 15 Fold:SAM domain-like
Superfamily:Rad51 N-terminal domain-like
Family:DNA repair protein Rad51, N-terminal domain
64c1y98A_



not modelled 97.5 12 PDB header:antitumor protein
Chain: A: PDB Molecule:breast cancer type 1 susceptibility protein;
PDBTitle: structure of the brct repeats of brca1 bound to a ctip2 phosphopeptide.
65c1l0bA_



not modelled 97.4 13 PDB header:unknown function
Chain: A: PDB Molecule:brca1;
PDBTitle: crystal structure of rat brca1 tandem-brct region
66c2azmB_



not modelled 97.4 11 PDB header:cell cycle
Chain: B: PDB Molecule:mediator of dna damage checkpoint protein 1;
PDBTitle: crystal structure of the mdc1 brct repeat in complex with2 the histone tail of gamma-h2ax
67d1t15a1



not modelled 97.4 12 Fold:BRCT domain
Superfamily:BRCT domain
Family:BRCT domain
68c1ixrA_



not modelled 97.3 16 PDB header:hydrolase
Chain: A: PDB Molecule:holliday junction dna helicase ruva;
PDBTitle: ruva-ruvb complex
69c2coeA_



not modelled 97.2 16 PDB header:transferase
Chain: A: PDB Molecule:deoxynucleotidyltransferase, terminal variant;
PDBTitle: solution structure of brct domain of terminal2 deoxynucleotidyltransferase
70c1z56C_



not modelled 97.2 16 PDB header:ligase
Chain: C: PDB Molecule:dna ligase iv;
PDBTitle: co-crystal structure of lif1p-lig4p
71c2w9mB_



not modelled 97.1 24 PDB header:dna replication
Chain: B: PDB Molecule:polymerase x;
PDBTitle: structure of family x dna polymerase from deinococcus2 radiodurans
72c1hjpA_



not modelled 97.1 21 PDB header:dna recombination
Chain: A: PDB Molecule:ruva;
PDBTitle: holliday junction binding protein ruva from e. coli
73c3kyhC_



not modelled 97.1 16 PDB header:protein binding
Chain: C: PDB Molecule:mrna-capping enzyme subunit alpha;
PDBTitle: saccharomyces cerevisiae cet1-ceg1 capping apparatus
74c3s24F_



not modelled 97.0 16 PDB header:hydrolase, transferase
Chain: F: PDB Molecule:mrna-capping enzyme;
PDBTitle: crystal structure of human mrna guanylyltransferase
75d1ckma2



not modelled 97.0 16 Fold:ATP-grasp
Superfamily:DNA ligase/mRNA capping enzyme, catalytic domain
Family:mRNA capping enzyme
76c2ihmA_



not modelled 97.0 22 PDB header:transferase/dna
Chain: A: PDB Molecule:dna polymerase mu;
PDBTitle: polymerase mu in ternary complex with gapped 11mer dna2 duplex and bound incoming nucleotide
77c2jw5A_



not modelled 97.0 13 PDB header:protein binding
Chain: A: PDB Molecule:dna polymerase lambda;
PDBTitle: polymerase lambda brct domain
78d1szpb1



not modelled 96.9 16 Fold:SAM domain-like
Superfamily:Rad51 N-terminal domain-like
Family:DNA repair protein Rad51, N-terminal domain
79c3t1nA_



not modelled 96.9 19 PDB header:cell cycle/peptide
Chain: A: PDB Molecule:microcephalin;
PDBTitle: structure of human microcephalin (mcph1) tandem brct domains in2 complex with a cdc27 phosphopeptide
80c2h5xA_



not modelled 96.9 18 PDB header:dna binding protein
Chain: A: PDB Molecule:holliday junction atp-dependent dna helicase ruva;
PDBTitle: ruva from mycobacterium tuberculosis
81c1cknA_



not modelled 96.9 16 PDB header:capping enzyme
Chain: A: PDB Molecule:mrna capping enzyme;
PDBTitle: structure of guanylylated mrna capping enzyme complexed2 with gtp
82d1ixra1



not modelled 96.8 21 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:DNA helicase RuvA subunit, middle domain
83d1p16a2



not modelled 96.7 20 Fold:ATP-grasp
Superfamily:DNA ligase/mRNA capping enzyme, catalytic domain
Family:mRNA capping enzyme
84c2hvsA_



not modelled 96.7 17 PDB header:ligase/dna/rna
Chain: A: PDB Molecule:t4 rna ligase 2;
PDBTitle: structure of t4 rna ligase 2 with nicked 5'-adenylated2 nucleic acid duplex containing a 2'-deoxyribonucleotide at3 the nick
85d1cuka2



not modelled 96.6 19 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:DNA helicase RuvA subunit, middle domain
86c1p16A_



not modelled 96.4 19 PDB header:transferase
Chain: A: PDB Molecule:mrna capping enzyme alpha subunit;
PDBTitle: structure of an mrna capping enzyme bound to the2 phosphorylated carboxyl-terminal domain of rna polymerase3 ii
87c1d8lA_



not modelled 96.1 20 PDB header:gene regulation
Chain: A: PDB Molecule:protein (holliday junction dna helicase ruva);
PDBTitle: e. coli holliday junction binding protein ruva nh2 region2 lacking domain iii
88d1pu6a_



not modelled 95.9 17 Fold:DNA-glycosylase
Superfamily:DNA-glycosylase
Family:3-Methyladenine DNA glycosylase III (MagIII)
89d1bvsa2



not modelled 95.8 26 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:DNA helicase RuvA subunit, middle domain
90c1kdhA_



not modelled 95.7 15 PDB header:transferase/dna
Chain: A: PDB Molecule:terminal deoxynucleotidyltransferase short
PDBTitle: binary complex of murine terminal deoxynucleotidyl2 transferase with a primer single stranded dna
91c2csdB_



not modelled 95.6 25 PDB header:isomerase
Chain: B: PDB Molecule:topoisomerase v;
PDBTitle: crystal structure of topoisomerase v (61 kda fragment)
92c2ep8A_



not modelled 95.6 12 PDB header:cell cycle
Chain: A: PDB Molecule:pescadillo homolog 1;
PDBTitle: solution structure of the brct domain from human pescadillo2 homolog 1
93c2dunA_



not modelled 95.4 15 PDB header:transferase
Chain: A: PDB Molecule:dna polymerase mu;
PDBTitle: solution structure of brct domain of dna polymerase mu
94d1lb2b_



not modelled 95.3 22 Fold:SAM domain-like
Superfamily:C-terminal domain of RNA polymerase alpha subunit
Family:C-terminal domain of RNA polymerase alpha subunit
95d1doqa_



not modelled 95.2 24 Fold:SAM domain-like
Superfamily:C-terminal domain of RNA polymerase alpha subunit
Family:C-terminal domain of RNA polymerase alpha subunit
96c8iczA_



not modelled 95.2 22 PDB header:transferase/dna
Chain: A: PDB Molecule:protein (dna polymerase beta (e.c.2.7.7.7));
PDBTitle: dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with2 seven base pairs of dna; soaked in the presence of of datp3 (1 millimolar), mncl2 (5 millimolar), and lithium sulfate4 (75 millimolar)
97c2bcuA_



not modelled 95.2 16 PDB header:transferase, lyase/dna
Chain: A: PDB Molecule:dna polymerase lambda;
PDBTitle: dna polymerase lambda in complex with a dna duplex2 containing an unpaired damp and a t:t mismatch
98d1z3eb1



not modelled 95.0 19 Fold:SAM domain-like
Superfamily:C-terminal domain of RNA polymerase alpha subunit
Family:C-terminal domain of RNA polymerase alpha subunit
99c2ziuA_



not modelled 94.9 14 PDB header:hydrolase
Chain: A: PDB Molecule:mus81 protein;
PDBTitle: crystal structure of the mus81-eme1 complex
100d2p6ra2



not modelled 94.7 20 Fold:Sec63 N-terminal domain-like
Superfamily:Sec63 N-terminal domain-like
Family:Achaeal helicase C-terminal domain
101d1cooa_



not modelled 94.6 21 Fold:SAM domain-like
Superfamily:C-terminal domain of RNA polymerase alpha subunit
Family:C-terminal domain of RNA polymerase alpha subunit
102d1kzyc2



not modelled 94.5 24 Fold:BRCT domain
Superfamily:BRCT domain
Family:53BP1
103d1l0ba2



not modelled 94.5 21 Fold:BRCT domain
Superfamily:BRCT domain
Family:BRCT domain
104d2a1ja1



not modelled 94.3 22 Fold:SAM domain-like
Superfamily:RuvA domain 2-like
Family:Hef domain-like
105c3f10A_



not modelled 94.2 30 PDB header:hydrolase, lyase
Chain: A: PDB Molecule:8-oxoguanine-dna-glycosylase;
PDBTitle: crystal structure of clostridium acetobutylicum 8-2 oxoguanine dna glycosylase in complex with 8-oxoguanosine
106d1s68a_



not modelled 93.9 20 Fold:ATP-grasp
Superfamily:DNA ligase/mRNA capping enzyme, catalytic domain
Family:RNA ligase
107c1s5lu_



not modelled 93.6 10 PDB header:photosynthesis
Chain: U: PDB Molecule:photosystem ii 12 kda extrinsic protein;
PDBTitle: architecture of the photosynthetic oxygen evolving center
108c2va8A_



not modelled 93.2 18 PDB header:hydrolase
Chain: A: PDB Molecule:ski2-type helicase;
PDBTitle: dna repair helicase hel308
109d2axtu1



not modelled 92.8 10 Fold:SAM domain-like
Superfamily:PsbU/PolX domain-like
Family:PsbU-like
110c2p6uA_



not modelled 92.7 15 PDB header:dna binding protein
Chain: A: PDB Molecule:afuhel308 helicase;
PDBTitle: apo structure of the hel308 superfamily 2 helicase
111d2noha1



not modelled 92.3 29 Fold:DNA-glycosylase
Superfamily:DNA-glycosylase
Family:DNA repair glycosylase, 2 C-terminal domains
112d1keaa_



not modelled 92.3 21 Fold:DNA-glycosylase
Superfamily:DNA-glycosylase
Family:Mismatch glycosylase
113d1kg2a_



not modelled 92.1 31 Fold:DNA-glycosylase
Superfamily:DNA-glycosylase
Family:Mismatch glycosylase
114d1in1a_



not modelled 91.7 11 Fold:BRCT domain
Superfamily:BRCT domain
Family:DNA ligase
115c1ut8B_



not modelled 91.5 15 PDB header:hydrolase
Chain: B: PDB Molecule:exodeoxyribonuclease;
PDBTitle: divalent metal ions (zinc) bound to t5 5'-exonuclease
116d1xo1a1



not modelled 91.3 15 Fold:SAM domain-like
Superfamily:5' to 3' exonuclease, C-terminal subdomain
Family:5' to 3' exonuclease, C-terminal subdomain
117c3n5nX_



not modelled 91.0 40 PDB header:hydrolase
Chain: X: PDB Molecule:a/g-specific adenine dna glycosylase;
PDBTitle: crystal structure analysis of the catalytic domain and interdomain2 connector of human muty homologue
118d1ul1x1



not modelled 91.0 23 Fold:SAM domain-like
Superfamily:5' to 3' exonuclease, C-terminal subdomain
Family:5' to 3' exonuclease, C-terminal subdomain
119d1rrqa1



not modelled 90.9 33 Fold:DNA-glycosylase
Superfamily:DNA-glycosylase
Family:Mismatch glycosylase
120d2abka_



not modelled 90.9 24 Fold:DNA-glycosylase
Superfamily:DNA-glycosylase
Family:Endonuclease III

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0