Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	D	F	P	Q	Q	L	E	A	C	V	K	Q	A	N	Q	A	L	S	R	F	I	A	P	L	P	F	Q	N	T	P	V	V	E	T	M	Q	Y	G	A	L	L	G	G	K	R	L	R	P	F	L	V	Y	A	T	G	H	M	F	G
Secondary structure
SS confidence
Disorder		?	?																							?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	S	T	N	T	L	D	A	P	A	A	A	V	E	C	I	H	A	Y	S	L	I	H	D	D	L	P	A	M	D	D	D	D	L	R	R	G	L	P	T	C	H	V	K	F	G	E	A	N	A	I	L	A	G	D	A	L	Q	T	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	F	S	I	L	S	D	A	D	M	P	E	V	S	D	R	D	R	I	S	M	I	S	E	L	A	S	A	S	G	I	A	G	M	C	G	G	Q	A	L	D	L	D	A	E	G	K	H	V	P	L	D	A	L	E	R	I	H	R	H
Secondary structure
SS confidence
Disorder											?	?	?	?	?															?	?															?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		K	T	G	A	L	I	R	A	A	V	R	L	G	A	L	S	A	G	D	K	G	R	R	A	L	P	V	L	D	K	Y	A	E	S	I	G	L	A	F	Q	V	Q	D	D	I	L	D	V	V	G	D	T	A	T	L	G	K	R	Q	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.
Sequence		A	D	Q	Q	L	G	K	S	T	Y	P	A	L	L	G	L	E	Q	A	R	K	K	A	R	D	L	I	D	D	A	R	Q	S	L	K	Q	L	A	E	Q	S	L	D	T	S	A	L	E	A	L	A	D	Y	I	I	Q	R	N	K
Secondary structure
SS confidence
Disorder																																								?	?	?	?	?													?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1rqj chain A Region: 1 - 299 Aligned: 299 Modelled: 299 Confidence: 100.0% Identity: 100% Fold: Terpenoid synthases Superfamily: Terpenoid synthases Family: Isoprenyl diphosphate synthases Phyre2 PDB 2for chain B Region: 1 - 298 Aligned: 281 Modelled: 281 Confidence: 100.0% Identity: 99% PDB header:transferase Chain: B: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of the shigella flexneri farnesyl pyrophosphate2 synthase complex with an isopentenyl pyrophosphate Phyre2 PDB 3ts7 chain B Region: 2 - 299 Aligned: 284 Modelled: 298 Confidence: 100.0% Identity: 49% PDB header:transferase Chain: B: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of farnesyl diphosphate synthase (target efi-501951)2 from methylococcus capsulatus Phyre2 PDB 1wy0 chain A Region: 2 - 298 Aligned: 286 Modelled: 292 Confidence: 100.0% Identity: 35% PDB header:transferase Chain: A: PDB Molecule:geranylgeranyl pyrophosphate synthetase; PDBTitle: crystal structure of geranylgeranyl pyrophosphate synthetase from2 pyrococcus horikoshii ot3 Phyre2 PDB 3mzv chain B Region: 3 - 299 Aligned: 281 Modelled: 297 Confidence: 100.0% Identity: 33% PDB header:transferase Chain: B: PDB Molecule:decaprenyl diphosphate synthase; PDBTitle: crystal structure of a decaprenyl diphosphate synthase from2 rhodobacter capsulatus Phyre2 PDB 3aqb chain D Region: 1 - 298 Aligned: 281 Modelled: 298 Confidence: 100.0% Identity: 29% PDB header:transferase Chain: D: PDB Molecule:component b of hexaprenyl diphosphate synthase; PDBTitle: m. luteus b-p 26 heterodimeric hexaprenyl diphosphate synthase in2 complex with magnesium Phyre2 PDB 3lsn chain A Region: 3 - 296 Aligned: 279 Modelled: 294 Confidence: 100.0% Identity: 47% PDB header:transferase Chain: A: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of putative geranyltranstransferase from pseudomonas2 fluorescens pf-5 complexed with magnesium Phyre2 PDB 3m9u chain D Region: 3 - 297 Aligned: 278 Modelled: 295 Confidence: 100.0% Identity: 41% PDB header:transferase Chain: D: PDB Molecule:farnesyl-diphosphate synthase; PDBTitle: crystal structure of geranylgeranyl pyrophosphate synthase2 from lactobacillus brevis atcc 367 Phyre2 PDB 3lom chain A Region: 4 - 298 Aligned: 277 Modelled: 277 Confidence: 100.0% Identity: 35% PDB header:transferase Chain: A: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of geranyltransferase from legionella2 pneumophila Phyre2 PDB 3oyr chain B Region: 3 - 298 Aligned: 279 Modelled: 292 Confidence: 100.0% Identity: 33% PDB header:transferase Chain: B: PDB Molecule:trans-isoprenyl diphosphate synthase; PDBTitle: crystal structure of polyprenyl synthase from caulobacter crescentus2 cb15 complexed with calcium and isoprenyl diphosphate Phyre2 PDB 3nf2 chain A Region: 2 - 295 Aligned: 284 Modelled: 294 Confidence: 100.0% Identity: 33% PDB header:transferase Chain: A: PDB Molecule:putative polyprenyl synthetase; PDBTitle: crystal structure of polyprenyl synthetase from streptomyces2 coelicolor a3(2) Phyre2 PDB 2h8o chain A Region: 2 - 296 Aligned: 273 Modelled: 278 Confidence: 100.0% Identity: 43% PDB header:transferase Chain: A: PDB Molecule:geranyltranstransferase; PDBTitle: the 1.6a crystal structure of the geranyltransferase from2 agrobacterium tumefaciens Phyre2 PDB 1rtr chain A Region: 7 - 297 Aligned: 271 Modelled: 275 Confidence: 100.0% Identity: 39% Fold: Terpenoid synthases Superfamily: Terpenoid synthases Family: Isoprenyl diphosphate synthases Phyre2 PDB 2j1p chain B Region: 2 - 294 Aligned: 274 Modelled: 279 Confidence: 100.0% Identity: 43% PDB header:transferase Chain: B: PDB Molecule:geranylgeranyl pyrophosphate synthetase; PDBTitle: geranylgeranyl diphosphate synthase from sinapis alba in2 complex with ggpp Phyre2 PDB 1fps chain A Region: 3 - 299 Aligned: 287 Modelled: 292 Confidence: 100.0% Identity: 24% Fold: Terpenoid synthases Superfamily: Terpenoid synthases Family: Isoprenyl diphosphate synthases Phyre2 PDB 3llw chain A Region: 2 - 296 Aligned: 274 Modelled: 280 Confidence: 100.0% Identity: 34% PDB header:transferase Chain: A: PDB Molecule:geranyltranstransferase (ispa); PDBTitle: crystal structure of geranyltransferase from helicobacter2 pylori 26695 Phyre2 PDB 3uca chain B Region: 7 - 298 Aligned: 265 Modelled: 274 Confidence: 100.0% Identity: 38% PDB header:transferase Chain: B: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of isoprenoid synthase (target efi-501974) from2 clostridium perfringens Phyre2 PDB 1wmw chain A Region: 8 - 297 Aligned: 277 Modelled: 283 Confidence: 100.0% Identity: 26% PDB header:transferase Chain: A: PDB Molecule:geranylgeranyl diphosphate synthetase; PDBTitle: crystal structure of geranulgeranyl diphosphate synthase from thermus2 thermophilus Phyre2 PDB 3cp6 chain A Region: 4 - 294 Aligned: 280 Modelled: 286 Confidence: 100.0% Identity: 24% PDB header:transferase Chain: A: PDB Molecule:farnesyl pyrophosphate synthetase; PDBTitle: crystal structure of human farnesyl diphosphate synthase (t201a2 mutant) complexed with mg and biphosphonate inhibitor Phyre2 PDB 2ogd chain B Region: 2 - 299 Aligned: 289 Modelled: 293 Confidence: 100.0% Identity: 22% PDB header:transferase Chain: B: PDB Molecule:farnesyl pyrophosphate synthase; PDBTitle: t. brucei farnesyl diphosphate synthase complexed with bisphosphonate2 bph-527 Phyre2 1 d1rqja_ 2 c2forB_ 3 c3ts7B_ 4 c1wy0A_ 5 c3mzvB_ 6 c3aqbD_ 7 c3lsnA_ 8 c3m9uD_ 9 c3lomA_ 10 c3oyrB_ 11 c3nf2A_ 12 c2h8oA_ 13 d1rtra_ 14 c2j1pB_ 15 d1fpsa_ 16 c3llwA_ 17 c3ucaB_ 18 c1wmwA_ 19 c3cp6A_ 20 c2ogdB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1rqja_ 100.0 100 Fold:Terpenoid synthases Superfamily:Terpenoid synthases Family:Isoprenyl diphosphate synthases 2 c2forB_ 100.0 99 PDB header:transferase Chain: B: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of the shigella flexneri farnesyl pyrophosphate2 synthase complex with an isopentenyl pyrophosphate 3 c3ts7B_ 100.0 49 PDB header:transferase Chain: B: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of farnesyl diphosphate synthase (target efi-501951)2 from methylococcus capsulatus 4 c1wy0A_ 100.0 35 PDB header:transferase Chain: A: PDB Molecule:geranylgeranyl pyrophosphate synthetase; PDBTitle: crystal structure of geranylgeranyl pyrophosphate synthetase from2 pyrococcus horikoshii ot3 5 c3mzvB_ 100.0 33 PDB header:transferase Chain: B: PDB Molecule:decaprenyl diphosphate synthase; PDBTitle: crystal structure of a decaprenyl diphosphate synthase from2 rhodobacter capsulatus 6 c3aqbD_ 100.0 29 PDB header:transferase Chain: D: PDB Molecule:component b of hexaprenyl diphosphate synthase; PDBTitle: m. luteus b-p 26 heterodimeric hexaprenyl diphosphate synthase in2 complex with magnesium 7 c3lsnA_ 100.0 47 PDB header:transferase Chain: A: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of putative geranyltranstransferase from pseudomonas2 fluorescens pf-5 complexed with magnesium 8 c3m9uD_ 100.0 41 PDB header:transferase Chain: D: PDB Molecule:farnesyl-diphosphate synthase; PDBTitle: crystal structure of geranylgeranyl pyrophosphate synthase2 from lactobacillus brevis atcc 367 9 c3lomA_ 100.0 35 PDB header:transferase Chain: A: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of geranyltransferase from legionella2 pneumophila 10 c3oyrB_ 100.0 33 PDB header:transferase Chain: B: PDB Molecule:trans-isoprenyl diphosphate synthase; PDBTitle: crystal structure of polyprenyl synthase from caulobacter crescentus2 cb15 complexed with calcium and isoprenyl diphosphate 11 c3nf2A_ 100.0 33 PDB header:transferase Chain: A: PDB Molecule:putative polyprenyl synthetase; PDBTitle: crystal structure of polyprenyl synthetase from streptomyces2 coelicolor a3(2) 12 c2h8oA_ 100.0 43 PDB header:transferase Chain: A: PDB Molecule:geranyltranstransferase; PDBTitle: the 1.6a crystal structure of the geranyltransferase from2 agrobacterium tumefaciens 13 d1rtra_ 100.0 39 Fold:Terpenoid synthases Superfamily:Terpenoid synthases Family:Isoprenyl diphosphate synthases 14 c2j1pB_ 100.0 43 PDB header:transferase Chain: B: PDB Molecule:geranylgeranyl pyrophosphate synthetase; PDBTitle: geranylgeranyl diphosphate synthase from sinapis alba in2 complex with ggpp 15 d1fpsa_ 100.0 24 Fold:Terpenoid synthases Superfamily:Terpenoid synthases Family:Isoprenyl diphosphate synthases 16 c3llwA_ 100.0 34 PDB header:transferase Chain: A: PDB Molecule:geranyltranstransferase (ispa); PDBTitle: crystal structure of geranyltransferase from helicobacter2 pylori 26695 17 c3ucaB_ 100.0 38 PDB header:transferase Chain: B: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of isoprenoid synthase (target efi-501974) from2 clostridium perfringens 18 c1wmwA_ 100.0 26 PDB header:transferase Chain: A: PDB Molecule:geranylgeranyl diphosphate synthetase; PDBTitle: crystal structure of geranulgeranyl diphosphate synthase from thermus2 thermophilus 19 c3cp6A_ 100.0 24 PDB header:transferase Chain: A: PDB Molecule:farnesyl pyrophosphate synthetase; PDBTitle: crystal structure of human farnesyl diphosphate synthase (t201a2 mutant) complexed with mg and biphosphonate inhibitor 20 c2ogdB_ 100.0 22 PDB header:transferase Chain: B: PDB Molecule:farnesyl pyrophosphate synthase; PDBTitle: t. brucei farnesyl diphosphate synthase complexed with bisphosphonate2 bph-527 21 c1yhlA_ not modelled 100.0 22 PDB header:transferase Chain: A: PDB Molecule:farnesyl pyrophosphate synthase; PDBTitle: structure of the complex of trypanosoma cruzi farnesyl diphosphate2 synthase with risedronate, dmapp and mg+2 22 c3m0gB_ not modelled 100.0 46 PDB header:transferase Chain: B: PDB Molecule:farnesyl diphosphate synthase; PDBTitle: crystal structure of putative farnesyl diphosphate synthase from2 rhodobacter capsulatus 23 c2f94F_ not modelled 100.0 24 PDB header:transferase Chain: F: PDB Molecule:farnesyl diphosphate synthase; PDBTitle: crystal structure of human fpps in complex with ibandronate 24 c3p8lB_ not modelled 100.0 38 PDB header:transferase Chain: B: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of polyprenyl synthase from enterococcus faecalis2 v583 25 d1v4ea_ not modelled 100.0 28 Fold:Terpenoid synthases Superfamily:Terpenoid synthases Family:Isoprenyl diphosphate synthases 26 c3ez3A_ not modelled 100.0 21 PDB header:lyase Chain: A: PDB Molecule:farnesyl pyrophosphate synthase, putative; PDBTitle: crystal structure of plasmodium vivax geranylgeranylpyrophosphate2 synthase pvx_092040 with zoledronate and ipp bound 27 c3npkB_ not modelled 100.0 36 PDB header:transferase Chain: B: PDB Molecule:geranyltranstransferase; PDBTitle: the crystal structure of geranyltranstransferase from campylobacter2 jejuni 28 c2e8xB_ not modelled 100.0 22 PDB header:transferase Chain: B: PDB Molecule:geranylgeranyl pyrophosphate synthetase; PDBTitle: s. cerevisiae geranylgeranyl pyrophosphate synthase in2 complex with magnesium and gpp 29 d2q80a1 not modelled 100.0 25 Fold:Terpenoid synthases Superfamily:Terpenoid synthases Family:Isoprenyl diphosphate synthases 30 c2o1oB_ not modelled 100.0 21 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative farnesyl pyrophosphate synthase; PDBTitle: cryptosporidium parvum putative polyprenyl pyrophosphate2 synthase (cgd4_2550) in complex with risedronate. 31 c3n3dB_ not modelled 100.0 30 PDB header:transferase Chain: B: PDB Molecule:geranylgeranyl pyrophosphate synthase; PDBTitle: crystal structure of geranylgeranyl pyrophosphate synthase from2 lactobacillus brevis atcc 367 32 c3ipiA_ not modelled 100.0 23 PDB header:transferase Chain: A: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of a geranyltranstransferase from the2 methanosarcina mazei 33 c3p8rA_ not modelled 100.0 58 PDB header:transferase Chain: A: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of polyprenyl synthase from vibrio cholerae 34 c3aq0G_ not modelled 100.0 27 PDB header:transferase Chain: G: PDB Molecule:geranyl diphosphate synthase; PDBTitle: ligand-bound form of arabidopsis medium/long-chain length prenyl2 pyrophosphate synthase (surface polar residue mutant) 35 c2azjB_ not modelled 100.0 21 PDB header:transferase Chain: B: PDB Molecule:geranylgeranyl pyrophosphate synthetase; PDBTitle: crystal structure for the mutant d81c of sulfolobus2 solfataricus hexaprenyl pyrophosphate synthase 36 c3lk5A_ not modelled 100.0 30 PDB header:transferase Chain: A: PDB Molecule:geranylgeranyl pyrophosphate synthase; PDBTitle: crystal structure of putative geranylgeranyl pyrophosphate synthase2 from corynebacterium glutamicum 37 c2j1oA_ not modelled 100.0 43 PDB header:transferase Chain: A: PDB Molecule:geranylgeranyl pyrophosphate synthetase; PDBTitle: geranylgeranyl diphosphate synthase from sinapis alba 38 c3lmdA_ not modelled 100.0 31 PDB header:transferase Chain: A: PDB Molecule:geranylgeranyl pyrophosphate synthase; PDBTitle: crystal structure of geranylgeranyl pyrophosphate synthase2 from corynebacterium glutamicum atcc 13032 39 c3rmgB_ not modelled 100.0 27 PDB header:transferase Chain: B: PDB Molecule:octaprenyl-diphosphate synthase; PDBTitle: crystal structure of geranylgeranyl pyrophosphate synthase from2 bacteroides thetaiotaomicron 40 c3kraB_ not modelled 100.0 22 PDB header:transferase Chain: B: PDB Molecule:geranyl diphosphate synthase small subunit; PDBTitle: mint heterotetrameric geranyl pyrophosphate synthase in2 complex with magnesium 41 c3tc1A_ not modelled 100.0 28 PDB header:transferase Chain: A: PDB Molecule:octaprenyl pyrophosphate synthase; PDBTitle: crystal structure of octaprenyl pyrophosphate synthase from2 helicobacter pylori 42 c3qkcB_ not modelled 100.0 18 PDB header:transferase Chain: B: PDB Molecule:geranyl diphosphate synthase small subunit; PDBTitle: crystal structure of geranyl diphosphate synthase small subunit from2 antirrhinum majus 43 c3oyrA_ not modelled 100.0 28 PDB header:transferase Chain: A: PDB Molecule:trans-isoprenyl diphosphate synthase; PDBTitle: crystal structure of polyprenyl synthase from caulobacter crescentus2 cb15 complexed with calcium and isoprenyl diphosphate 44 c2ftzA_ not modelled 100.0 30 PDB header:transferase Chain: A: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of geranyltranstransferase (ec 2.5.1.10) (tm0161)2 from thermotoga maritima at 1.90 a resolution 45 d1ezfa_ not modelled 96.3 27 Fold:Terpenoid synthases Superfamily:Terpenoid synthases Family:Squalene synthase 46 c2zcpA_ not modelled 95.7 14 PDB header:transferase Chain: A: PDB Molecule:dehydrosqualene synthase; PDBTitle: crystal structure of the c(30) carotenoid dehydrosqualene2 synthase from staphylococcus aureus complexed with3 farnesyl thiopyrophosphate 47 d1n1ba2 not modelled 75.3 13 Fold:Terpenoid synthases Superfamily:Terpenoid synthases Family:Terpenoid cyclase C-terminal domain 48 c1hx9A_ not modelled 72.7 16 PDB header:lyase Chain: A: PDB Molecule:5-epi-aristolochene synthase; PDBTitle: crystal structure of teas w273s form 1 49 c3n0fA_ not modelled 70.3 12 PDB header:lyase Chain: A: PDB Molecule:isoprene synthase; PDBTitle: crystal structure of isoprene synthase from grey poplar leaves2 (populus x canescens) 50 c3saeA_ not modelled 67.5 15 PDB header:lyase Chain: A: PDB Molecule:alpha-bisabolene synthase; PDBTitle: structure of a three-domain sesquiterpene synthase: a prospective2 target for advanced biofuels production 51 c1n20A_ not modelled 66.9 12 PDB header:isomerase Chain: A: PDB Molecule:(+)-bornyl diphosphate synthase; PDBTitle: (+)-bornyl diphosphate synthase: complex with mg and 3-aza-2 2,3-dihydrogeranyl diphosphate 52 d5easa2 not modelled 59.7 16 Fold:Terpenoid synthases Superfamily:Terpenoid synthases Family:Terpenoid cyclase C-terminal domain 53 c2ongA_ not modelled 58.9 10 PDB header:lyase Chain: A: PDB Molecule:4s-limonene synthase; PDBTitle: crystal structure of of limonene synthase with 2-2 fluorogeranyl diphosphate (fgpp). 54 c3g4dB_ not modelled 56.3 9 PDB header:lyase Chain: B: PDB Molecule:(+)-delta-cadinene synthase isozyme xc1; PDBTitle: crystal structure of (+)-delta-cadinene synthase from gossypium2 arboreum and evolutionary divergence of metal binding motifs for3 catalysis 55 d2o3la1 not modelled 55.7 16 Fold:Left-handed superhelix Superfamily:BH3980-like Family:BH3980-like 56 c3p5rB_ not modelled 55.6 13 PDB header:lyase Chain: B: PDB Molecule:taxadiene synthase; PDBTitle: crystal structure of taxadiene synthase from pacific yew (taxus2 brevifolia) in complex with mg2+ and 2-fluorogeranylgeranyl3 diphosphate 57 c3s9vD_ not modelled 51.7 9 PDB header:lyase, isomerase Chain: D: PDB Molecule:abietadiene synthase, chloroplastic; PDBTitle: abietadiene synthase from abies grandis 58 d2hh6a1 not modelled 43.7 29 Fold:Left-handed superhelix Superfamily:BH3980-like Family:BH3980-like 59 c2j5cB_ not modelled 39.1 14 PDB header:lyase Chain: B: PDB Molecule:1,8-cineole synthase; PDBTitle: rational conversion of substrate and product specificity2 in a monoterpene synthase. structural insights into the3 molecular basis of rapid evolution. 60 d2htja1 not modelled 34.0 36 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:FaeA-like 61 c3byvA_ not modelled 28.8 24 PDB header:transferase Chain: A: PDB Molecule:rhoptry kinase; PDBTitle: crystal structure of toxoplasma gondii specific rhoptry2 antigen kinase domain 62 c3q60A_ not modelled 24.3 10 PDB header:transferase Chain: A: PDB Molecule:rop5b; PDBTitle: crystal structure of virulent allele rop5b pseudokinase domain bound2 to atp 63 d2o4ta1 not modelled 23.8 23 Fold:Left-handed superhelix Superfamily:BH3980-like Family:BH3980-like 64 c3e7eA_ not modelled 18.3 24 PDB header:transferase Chain: A: PDB Molecule:mitotic checkpoint serine/threonine-protein kinase bub1; PDBTitle: structure and substrate recruitment of the human spindle checkpoint2 kinase bub 65 c3lg5A_ not modelled 18.1 11 PDB header:lyase Chain: A: PDB Molecule:epi-isozizaene synthase; PDBTitle: f198a epi-isozizaene synthase: complex with mg, inorganic2 pyrophosphate and benzyl triethyl ammonium cation 66 c2jiiA_ not modelled 16.2 19 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase vrk3 molecule: vaccinia PDBTitle: structure of vaccinia related kinase 3 67 c2v62A_ not modelled 16.0 24 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase vrk2; PDBTitle: structure of vaccinia-related kinase 2 68 c3dzoA_ not modelled 12.8 24 PDB header:transferase Chain: A: PDB Molecule:rhoptry kinase domain; PDBTitle: crystal structure of a rhoptry kinase from toxoplasma gondii 69 c1tqmA_ not modelled 10.3 29 PDB header:ribosome Chain: A: PDB Molecule:conserved hypothetical protein; PDBTitle: crystal structure of a. fulgidus rio2 serine protein kinase bound to2 amppnp 70 c2j0kB_ not modelled 9.8 14 PDB header:transferase Chain: B: PDB Molecule:focal adhesion kinase 1; PDBTitle: crystal structure of a fragment of focal adhesion kinase2 containing the ferm and kinase domains. 71 c2wtkC_ not modelled 9.4 19 PDB header:transferase/metal-binding protein Chain: C: PDB Molecule:serine/threonine-protein kinase 11; PDBTitle: structure of the heterotrimeric lkb1-stradalpha-mo25alpha2 complex 72 c3qa8A_ not modelled 8.4 33 PDB header:immune system, signaling protein Chain: A: PDB Molecule:mgc80376 protein; PDBTitle: crystal structure of inhibitor of kappa b kinase beta 73 c2ctoA_ not modelled 8.3 30 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:novel protein; PDBTitle: solution structure of the hmg box like domain from human2 hypothetical protein flj14904 74 c3c4yA_ not modelled 8.2 24 PDB header:transferase Chain: A: PDB Molecule:rhodopsin kinase; PDBTitle: crystal structure of apo form of g protein coupled receptor kinase 12 at 7.51a 75 c3a1yF_ not modelled 8.2 36 PDB header:ribosomal protein Chain: F: PDB Molecule:50s ribosomal protein p1 (l12p); PDBTitle: the structure of protein complex 76 c2pziA_ not modelled 8.0 29 PDB header:transferase Chain: A: PDB Molecule:probable serine/threonine-protein kinase pkng; PDBTitle: crystal structure of protein kinase pkng from mycobacterium2 tuberculosis in complex with tetrahydrobenzothiophene ax20017 77 c3fbvL_ not modelled 7.8 38 PDB header:transferase, hydrolase Chain: L: PDB Molecule:serine/threonine-protein kinase/endoribonuclease ire1; PDBTitle: crystal structure of the oligomer formed by the kinase-ribonuclease2 domain of ire1 78 d1ps1a_ not modelled 7.4 15 Fold:Terpenoid synthases Superfamily:Terpenoid synthases Family:Aristolochene/pentalenene synthase 79 c2oa6B_ not modelled 7.3 14 PDB header:lyase Chain: B: PDB Molecule:aristolochene synthase; PDBTitle: aristolochene synthase from aspergillus terreus complexed with2 pyrophosphate 80 c3op5B_ not modelled 7.3 24 PDB header:transferase Chain: B: PDB Molecule:serine/threonine-protein kinase vrk1; PDBTitle: human vaccinia-related kinase 1 81 c2acxB_ not modelled 7.1 19 PDB header:transferase Chain: B: PDB Molecule:g protein-coupled receptor kinase 6; PDBTitle: crystal structure of g protein coupled receptor kinase 6 bound to2 amppnp 82 c1ym7C_ not modelled 6.9 19 PDB header:transferase Chain: C: PDB Molecule:beta-adrenergic receptor kinase 1; PDBTitle: g protein-coupled receptor kinase 2 (grk2) 83 c2ozoA_ not modelled 6.7 14 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70 84 c1u57A_ not modelled 6.6 13 PDB header:viral protein Chain: A: PDB Molecule:gag polyprotein; PDBTitle: nmr structure of the (345-392)gag sequence from hiv-1 85 c3cvjB_ not modelled 6.5 15 PDB header:isomerase Chain: B: PDB Molecule:putative phosphoheptose isomerase; PDBTitle: crystal structure of a putative phosphoheptose isomerase (bh3325) from2 bacillus halodurans c-125 at 2.00 a resolution 86 c2vwiC_ not modelled 6.5 29 PDB header:transferase Chain: C: PDB Molecule:serine/threonine-protein kinase osr1; PDBTitle: structure of the osr1 kinase, a hypertension drug target 87 c3i3aC_ not modelled 6.2 9 PDB header:transferase Chain: C: PDB Molecule:acyl-[acyl-carrier-protein]--udp-n- PDBTitle: structural basis for the sugar nucleotide and acyl chain2 selectivity of leptospira interrogans lpxa 88 d1vjja1 not modelled 6.1 67 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:Transglutaminase N-terminal domain 89 d1g0da1 not modelled 6.1 67 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:Transglutaminase N-terminal domain 90 c3t98A_ not modelled 5.9 40 PDB header:protein transport Chain: A: PDB Molecule:nuclear pore complex protein nup54; PDBTitle: molecular architecture of the transport channel of the nuclear pore2 complex: nup54/nup58 91 c3pjaK_ not modelled 5.9 2 PDB header:hydrolase Chain: K: PDB Molecule:translin-associated protein x; PDBTitle: crystal structure of human c3po complex 92 d2q3za1 not modelled 5.9 67 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:Transglutaminase N-terminal domain 93 c2c47D_ not modelled 5.8 29 PDB header:transferase Chain: D: PDB Molecule:casein kinase 1 gamma 2 isoform; PDBTitle: structure of casein kinase 1 gamma 2 94 d1sq8a_ not modelled 5.7 16 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:Phage repressors 95 c1hm4A_ not modelled 5.5 11 PDB header:lyase Chain: A: PDB Molecule:pentalenene synthase; PDBTitle: n219l pentalenene synthase 96 c2r17C_ not modelled 5.5 20 PDB header:protein transport Chain: C: PDB Molecule:vacuolar protein sorting-associated protein 35; PDBTitle: functional architecture of the retromer cargo-recognition complex 97 d1riqa1 not modelled 5.4 20 Fold:Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Superfamily:Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Family:Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 98 c2vuwA_ not modelled 5.2 29 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase haspin; PDBTitle: structure of human haspin kinase domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0