PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3cp6A_

Fold library id	PDB Header	Molecule	Title
c3cp6A_	PDB header: transferase	Chain: A: PDB Molecule: farnesyl pyrophosphate synthetase;	PDBTitle: crystal structure of human farnesyl diphosphate synthase2 (t201a mutant) complexed with mg and biphosphonate3 inhibitor

Links to external resources
Added to library: Tue Mar 16 14:05:08 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence A Q E K Q D F V Q H F S Q I V R V L T E H P E I G D A I A R L K E V L E Y N A I G G K Y N R G L T V V V A F R E L V E P R K Q D A D S L Q R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S S S S
S
G G G

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence A W T V G W C V E L L Q A F F L V A D D I M D S S L T R R G Q I C W Y Q K P G V G L D A I N D A N L L E A C I Y R L L K L Y C R E Q P Y Y L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
T T
G G G S T T T G G G T T S T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence N L I E L F L Q S S Y Q T E I G Q T L D L L T A P Q G N V D L V R F T E K R Y K S I V K Y K A A F Y S F Y L P I A A A M Y M A G I D G E K E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T T
S T T
S T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence H A N A K K I L L E M G E F F Q I Q D D Y L D L F G D P S V T G K I G T D I Q D N K C S W L V V Q C L Q R A T P E Q Y Q I L K E N Y G Q K E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S S
T T T T T
T T

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . .

Sequence A E K V A R V K A L Y E E L D L P A V F L Q Y E E D S Y S H I M A L I E Q Y A A P L P P A V F L G L A R K I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
T T S
T T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	A	Q	E	K	Q	D	F	V	Q	H	F	S	Q	I	V	R	V	L	T	E	H	P	E	I	G	D	A	I	A	R	L	K	E	V	L	E	Y	N	A	I	G	G	K	Y	N	R	G	L	T	V	V	V	A	F	R	E	L	V	E	P	R	K	Q	D	A	D	S	L	Q	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S																																				S	S	S	S																S		G	G	G
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	A	W	T	V	G	W	C	V	E	L	L	Q	A	F	F	L	V	A	D	D	I	M	D	S	S	L	T	R	R	G	Q	I	C	W	Y	Q	K	P	G	V	G	L	D	A	I	N	D	A	N	L	L	E	A	C	I	Y	R	L	L	K	L	Y	C	R	E	Q	P	Y	Y	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																							T	T					T	T				G	G	G	S	T	T	T	G	G	G																					T	T	S	T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	N	L	I	E	L	F	L	Q	S	S	Y	Q	T	E	I	G	Q	T	L	D	L	L	T	A	P	Q	G	N	V	D	L	V	R	F	T	E	K	R	Y	K	S	I	V	K	Y	K	A	A	F	Y	S	F	Y	L	P	I	A	A	A	M	Y	M	A	G	I	D	G	E	K	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																							T			T	T				S	T	T																			S											T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	H	A	N	A	K	K	I	L	L	E	M	G	E	F	F	Q	I	Q	D	D	Y	L	D	L	F	G	D	P	S	V	T	G	K	I	G	T	D	I	Q	D	N	K	C	S	W	L	V	V	Q	C	L	Q	R	A	T	P	E	Q	Y	Q	I	L	K	E	N	Y	G	Q	K	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																										S						S	S				T	T	T	T	T																									T	T
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.
Sequence	A	E	K	V	A	R	V	K	A	L	Y	E	E	L	D	L	P	A	V	F	L	Q	Y	E	E	D	S	Y	S	H	I	M	A	L	I	E	Q	Y	A	A	P	L	P	P	A	V	F	L	G	L	A	R	K	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														T	T																									T	T	S		T								T	T