1 c3ohmB_
100.0
38
PDB header: signaling protein / hydrolaseChain: B: PDB Molecule: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterasePDBTitle: crystal structure of activated g alpha q bound to its effector2 phospholipase c beta 3
2 c3qr0A_
100.0
35
PDB header: hydrolaseChain: A: PDB Molecule: phospholipase c-beta (plc-beta);PDBTitle: crystal structure of s. officinalis plc21
3 c2fjuB_
100.0
36
PDB header: signaling protein,apoptosis/hydrolaseChain: B: PDB Molecule: 1-phosphatidylinositol-4,5-bisphosphatePDBTitle: activated rac1 bound to its effector phospholipase c beta 2
4 c1djyB_
100.0
45
PDB header: lipid degradationChain: B: PDB Molecule: phosphoinositide-specific phospholipase c,PDBTitle: phosphoinositide-specific phospholipase c-delta1 from rat2 complexed with inositol-2,4,5-trisphosphate
5 d2zkmx4
100.0
59
Fold: TIM beta/alpha-barrelSuperfamily: PLC-like phosphodiesterasesFamily: Mammalian PLC6 d1qasa3
100.0
65
Fold: TIM beta/alpha-barrelSuperfamily: PLC-like phosphodiesterasesFamily: Mammalian PLC7 c2lqnA_
100.0
19
PDB header: signaling proteinChain: A: PDB Molecule: crk-like protein;PDBTitle: solution structure of crkl
8 c2eyzA_
100.0
18
PDB header: signaling proteinChain: A: PDB Molecule: v-crk sarcoma virus ct10 oncogene homologPDBTitle: ct10-regulated kinase isoform ii
9 c3gqiB_
100.0
48
PDB header: transferase/transferase inhibitorChain: B: PDB Molecule: phospholipase c-gamma-1;PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates
10 d2zkmx2
100.0
26
Fold: C2 domain-likeSuperfamily: C2 domain (Calcium/lipid-binding domain, CaLB)Family: PLC-like (P variant)11 c2shpA_
100.0
31
PDB header: tyrosine phosphataseChain: A: PDB Molecule: shp-2;PDBTitle: tyrosine phosphatase shp-2
12 c2b3oA_
100.0
30
PDB header: hydrolaseChain: A: PDB Molecule: tyrosine-protein phosphatase, non-receptor typePDBTitle: crystal structure of human tyrosine phosphatase shp-1
13 c3ps5A_
100.0
30
PDB header: hydrolase, signaling proteinChain: A: PDB Molecule: tyrosine-protein phosphatase non-receptor type 6;PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1
14 d1qasa2
100.0
32
Fold: C2 domain-likeSuperfamily: C2 domain (Calcium/lipid-binding domain, CaLB)Family: PLC-like (P variant)15 c2eyyA_
99.9
28
PDB header: signaling proteinChain: A: PDB Molecule: v-crk sarcoma virus ct10 oncogene homologPDBTitle: ct10-regulated kinase isoform i
16 c2oq1A_
99.9
26
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase zap-70;PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide
17 c2dvjA_
99.9
29
PDB header: signaling proteinChain: A: PDB Molecule: v-crk sarcoma virus ct10 oncogene homolog,PDBTitle: phosphorylated crk-ii
18 c4fl2A_
99.9
25
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase syk;PDBTitle: structural and biophysical characterization of the syk activation2 switch
19 c3qwyA_
99.9
26
PDB header: signaling proteinChain: A: PDB Molecule: cell death abnormality protein 2;PDBTitle: ced-2
20 c2ozoA_
99.9
25
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase zap-70;PDBTitle: autoinhibited intact human zap-70
21 c3qwxX_
not modelled
99.9
26
PDB header: signaling proteinChain: X: PDB Molecule: cell death abnormality protein 2;PDBTitle: ced-2 1-174
22 d2zkmx3
not modelled
99.9
20
Fold: PH domain-like barrelSuperfamily: PH domain-likeFamily: Pleckstrin-homology domain (PH domain)23 c1a81E_
not modelled
99.9
25
PDB header: complex (transferase/peptide)Chain: E: PDB Molecule: syk kinase;PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam
24 d1djxb1
not modelled
99.8
21
Fold: EF Hand-likeSuperfamily: EF-handFamily: EF-hand modules in multidomain proteins25 d2zkmx1
not modelled
99.8
16
Fold: EF Hand-likeSuperfamily: EF-handFamily: EF-hand modules in multidomain proteins26 c3h4wA_
not modelled
99.8
23
PDB header: hydrolaseChain: A: PDB Molecule: phosphatidylinositol-specific phospholipase c1;PDBTitle: structure of a ca+2 dependent phosphatidylinositol-specific2 phospholipase c (pi-plc) enzyme from streptomyces antibioticus
27 d1qasa1
not modelled
99.7
21
Fold: EF Hand-likeSuperfamily: EF-handFamily: EF-hand modules in multidomain proteins28 d1maia_
not modelled
99.7
19
Fold: PH domain-like barrelSuperfamily: PH domain-likeFamily: Pleckstrin-homology domain (PH domain)29 c2vszA_
not modelled
99.6
18
PDB header: apoptosisChain: A: PDB Molecule: engulfment and cell motility protein 1;PDBTitle: crystal structure of the elmo1 ph domain
30 c2fjlA_
not modelled
99.6
35
PDB header: hydrolaseChain: A: PDB Molecule: 1-phosphatidylinositol-4,5-bisphosphatePDBTitle: solution structure of the split ph domain in phospholipase2 c-gamma1
31 c2xp1A_
not modelled
99.5
15
PDB header: transcriptionChain: A: PDB Molecule: spt6;PDBTitle: structure of the tandem sh2 domains from antonospora locustae2 transcription elongation factor spt6
32 c2hdxB_
not modelled
99.5
28
PDB header: signaling proteinChain: B: PDB Molecule: sh2-b ph domain containing signaling mediator 1PDBTitle: crystal structure of the src homology-2 domain of sh2-b in2 complex with jak2 ptyr813 phosphopeptide
33 c3or8A_
not modelled
99.5
16
PDB header: transcriptionChain: A: PDB Molecule: transcription elongation factor spt6;PDBTitle: a tandem sh2 domain in transcription elongation factor spt6
34 c2gsbA_
not modelled
99.5
32
PDB header: signaling proteinChain: A: PDB Molecule: ras gtpase-activating protein 1;PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1
35 c2y3aB_
not modelled
99.5
26
PDB header: transferaseChain: B: PDB Molecule: phosphatidylinositol 3-kinase regulatory subunit beta;PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
36 c2dx0B_
not modelled
99.5
54
PDB header: hydrolaseChain: B: PDB Molecule: phospholipase c, gamma 2;PDBTitle: crystal structure of the n-terminal sh2 domain of mouse2 phospholipase c-gamma 2
37 c1griA_
not modelled
99.5
30
PDB header: signal transduction adaptorChain: A: PDB Molecule: growth factor bound protein 2;PDBTitle: grb2
38 c3hizB_
not modelled
99.4
29
PDB header: transferase/oncoproteinChain: B: PDB Molecule: phosphatidylinositol 3-kinase regulatory subunitPDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha
39 d3c7ia1
not modelled
99.4
35
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain40 d1gmia_
not modelled
99.4
18
Fold: C2 domain-likeSuperfamily: C2 domain (Calcium/lipid-binding domain, CaLB)Family: PLC-like (P variant)41 c2fo0A_
not modelled
99.4
19
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase abl1 (1b isoform);PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
42 d2oq1a1
not modelled
99.4
24
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain43 d2oq1a2
not modelled
99.4
30
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain44 d2eyva1
not modelled
99.4
38
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain45 c2q3xA_
not modelled
99.4
16
PDB header: transport proteinChain: A: PDB Molecule: regulating synaptic membrane exocytosis protein 1;PDBTitle: the rim1alpha c2b domain
46 c2dlzA_
not modelled
99.4
28
PDB header: signaling proteinChain: A: PDB Molecule: protein vav-2;PDBTitle: solution structure of the sh2 domain of human protein vav-2
47 d2qmsa1
not modelled
99.4
25
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain48 d1fhsa_
not modelled
99.4
33
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain49 c2eo3A_
not modelled
99.4
32
PDB header: signaling proteinChain: A: PDB Molecule: crk-like protein;PDBTitle: solution structure of the sh2 domain from human crk-like2 protein
50 d1csya_
not modelled
99.4
26
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain51 d2shpa2
not modelled
99.4
32
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain52 d1a81e2
not modelled
99.4
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain53 d2izva2
not modelled
99.4
25
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain54 c3m7fB_
not modelled
99.4
24
PDB header: signaling protein/ligaseChain: B: PDB Molecule: e3 ubiquitin-protein ligase nedd4;PDBTitle: crystal structure of the nedd4 c2/grb10 sh2 complex
55 d1a81a1
not modelled
99.4
25
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain56 d2nq3a1
not modelled
99.4
18
Fold: C2 domain-likeSuperfamily: C2 domain (Calcium/lipid-binding domain, CaLB)Family: PLC-like (P variant)57 c2nq3A_
not modelled
99.4
18
PDB header: ligaseChain: A: PDB Molecule: itchy homolog e3 ubiquitin protein ligase;PDBTitle: crystal structure of the c2 domain of human itchy homolog2 e3 ubiquitin protein ligase
58 d1nrva_
not modelled
99.4
24
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain59 d1a81a2
not modelled
99.4
26
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain60 d2r83a1
not modelled
99.4
21
Fold: C2 domain-likeSuperfamily: C2 domain (Calcium/lipid-binding domain, CaLB)Family: Synaptotagmin-like (S variant)61 c2crhA_
not modelled
99.4
25
PDB header: signaling proteinChain: A: PDB Molecule: vav proto-oncogene;PDBTitle: solution structure of the sh2 domain of human proto-2 oncogene protein vav1
62 c1oplA_
not modelled
99.4
20
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase;PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
63 d1rjaa_
not modelled
99.4
30
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain64 d1a81e1
not modelled
99.4
25
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain65 c2l3sA_
not modelled
99.4
11
PDB header: structural proteinChain: A: PDB Molecule: autoinhibited crk protein;PDBTitle: structure of the autoinhibited crk
66 c2dlyA_
not modelled
99.4
31
PDB header: transferaseChain: A: PDB Molecule: fyn-related kinase;PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase
67 c2augB_
not modelled
99.4
27
PDB header: signaling proteinChain: B: PDB Molecule: growth factor receptor-bound protein 14;PDBTitle: crystal structure of the grb14 sh2 domain
68 c3l9bA_
not modelled
99.4
14
PDB header: membrane proteinChain: A: PDB Molecule: otoferlin;PDBTitle: crystal structure of rat otoferlin c2a
69 c2dmhA_
not modelled
99.3
23
PDB header: lipid binding proteinChain: A: PDB Molecule: myoferlin;PDBTitle: solution structure of the first c2 domain of human myoferlin
70 c3kwtA_
not modelled
99.3
22
PDB header: metal binding proteinChain: A: PDB Molecule: munc13-1;PDBTitle: munc13-1 c2b-domain, calcium-free
71 c2ci8A_
not modelled
99.3
24
PDB header: translationChain: A: PDB Molecule: cytoplasmic protein nck1;PDBTitle: sh2 domain of human nck1 adaptor protein - uncomplexed
72 c2eo6A_
not modelled
99.3
26
PDB header: signaling proteinChain: A: PDB Molecule: b-cell linker protein;PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk
73 d1blja_
not modelled
99.3
28
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain74 c2chdA_
not modelled
99.3
24
PDB header: protein transportChain: A: PDB Molecule: rabphilin-3a;PDBTitle: crystal structure of the c2a domain of rabphilin-3a
75 d1pica_
not modelled
99.3
28
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain76 c3a98B_
not modelled
99.3
18
PDB header: signaling proteinChain: B: PDB Molecule: engulfment and cell motility protein 1;PDBTitle: crystal structure of the complex of the interacting regions of dock22 and elmo1
77 d1rlwa_
not modelled
99.3
17
Fold: C2 domain-likeSuperfamily: C2 domain (Calcium/lipid-binding domain, CaLB)Family: PLC-like (P variant)78 d2cs0a1
not modelled
99.3
29
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain79 c1y57A_
not modelled
99.3
29
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase src;PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
80 c2cr4A_
not modelled
99.3
23
PDB header: signaling proteinChain: A: PDB Molecule: sh3 domain-binding protein 2;PDBTitle: solution structure of the sh2 domain of human sh3bp2 protein
81 c2kk6A_
not modelled
99.3
34
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase fer;PDBTitle: solution structure of sh2 domain of proto-oncogene tyrosine-2 protein kinase fer from homo sapiens, northeast structural3 genomics consortium (nesg) target hr3461d
82 d1qcfa2
not modelled
99.3
25
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain83 d1opka2
not modelled
99.3
30
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain84 d1jyra_
not modelled
99.3
36
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain85 c1ka6A_
not modelled
99.3
23
PDB header: immune systemChain: A: PDB Molecule: sh2 domain protein 1a;PDBTitle: sap/sh2d1a bound to peptide n-py
86 d1rpya_
not modelled
99.3
26
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain87 d2fcia1
not modelled
99.3
30
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain88 c3nsjA_
not modelled
99.3
18
PDB header: immune systemChain: A: PDB Molecule: perforin-1;PDBTitle: the x-ray crystal structure of lymphocyte perforin
89 c2dcrA_
not modelled
99.3
30
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase fes/fps;PDBTitle: fully automated solution structure determination of the fes2 sh2 domain
90 d2shpa3
not modelled
99.3
34
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain91 c2ysxA_
not modelled
99.3
31
PDB header: signaling proteinChain: A: PDB Molecule: signaling inositol polyphosphate phosphatasePDBTitle: solution structure of the human ship sh2 domain
92 c3fbkB_
not modelled
99.3
13
PDB header: signaling proteinChain: B: PDB Molecule: regulator of g-protein signaling 3;PDBTitle: crystal structure of the c2 domain of the human regulator2 of g-protein signaling 3 isoform 6 (rgp3), northeast3 structural genomics consortium target hr5550a
93 d1ayaa_
not modelled
99.2
34
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain94 c2lctA_
not modelled
99.2
25
PDB header: signaling proteinChain: A: PDB Molecule: proto-oncogene vav;PDBTitle: solution structure of the vav1 sh2 domain complexed with a syk-derived2 doubly phosphorylated peptide
95 d1r1qa_
not modelled
99.2
28
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain96 c1x6cA_
not modelled
99.2
26
PDB header: signaling proteinChain: A: PDB Molecule: tyrosine-protein phosphatase, non-receptor typePDBTitle: solution structures of the sh2 domain of human protein-2 tyrosine phosphatase shp-1
97 c1x27F_
not modelled
99.2
25
PDB header: signaling proteinChain: F: PDB Molecule: proto-oncogene tyrosine-protein kinase lck;PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas
98 d1bkla_
not modelled
99.2
32
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain99 c2ablA_
not modelled
99.2
31
PDB header: transferaseChain: A: PDB Molecule: abl tyrosine kinase;PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase
100 d1dsya_
not modelled
99.2
20
Fold: C2 domain-likeSuperfamily: C2 domain (Calcium/lipid-binding domain, CaLB)Family: Synaptotagmin-like (S variant)101 c1mv3A_
not modelled
99.2
12
PDB header: endocytosis/exocytosisChain: A: PDB Molecule: myc box dependent interacting protein 1;PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc
102 d1d4ta_
not modelled
99.2
24
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain103 c2nsqA_
not modelled
99.2
23
PDB header: ligaseChain: A: PDB Molecule: e3 ubiquitin-protein ligase nedd4-like protein;PDBTitle: crystal structure of the c2 domain of the human e3 ubiquitin-protein2 ligase nedd4-like protein
104 c2fk9A_
not modelled
99.2
19
PDB header: transferaseChain: A: PDB Molecule: protein kinase c, eta type;PDBTitle: human protein kinase c, eta
105 c2z0uB_
not modelled
99.2
20
PDB header: lipid binding proteinChain: B: PDB Molecule: ww domain-containing protein 1;PDBTitle: crystal structure of c2 domain of kibra protein
106 c1rqqC_
not modelled
99.2
29
PDB header: transferase/signaling proteinChain: C: PDB Molecule: adaptor protein aps;PDBTitle: crystal structure of the insulin receptor kinase in complex2 with the sh2 domain of aps
107 d1xa6a2
not modelled
99.2
29
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain108 d1f2fa_
not modelled
99.2
32
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain109 d1lkka_
not modelled
99.2
26
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain110 d1a25a_
not modelled
99.2
17
Fold: C2 domain-likeSuperfamily: C2 domain (Calcium/lipid-binding domain, CaLB)Family: Synaptotagmin-like (S variant)111 c3jzyA_
not modelled
99.2
20
PDB header: endocytosisChain: A: PDB Molecule: intersectin 2;PDBTitle: crystal structure of human intersectin 2 c2 domain
112 c1k9aB_
not modelled
99.2
30
PDB header: transferaseChain: B: PDB Molecule: carboxyl-terminal src kinase;PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
113 c2h8hA_
not modelled
99.2
29
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase src;PDBTitle: src kinase in complex with a quinazoline inhibitor
114 c2ge9A_
not modelled
99.2
30
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase btk;PDBTitle: solution structures of the sh2 domain of bruton's tyrosine2 kinase
115 d1i3za_
not modelled
99.2
26
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain116 c3nhnA_
not modelled
99.2
25
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase hck;PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region
117 c2c0iA_
not modelled
99.2
25
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase hck;PDBTitle: src family kinase hck with bound inhibitor a-420983
118 c2el8A_
not modelled
99.2
21
PDB header: signaling proteinChain: A: PDB Molecule: signal-transducing adaptor protein 2;PDBTitle: solution structure of the human stap2 sh2 domain
119 c2hmhA_
not modelled
99.2
17
PDB header: cytokine regulatorChain: A: PDB Molecule: suppressor of cytokine signaling 3;PDBTitle: crystal structure of socs3 in complex with gp130(ptyr757)2 phosphopeptide.
120 d1k9aa2
not modelled
99.2
33
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
