PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2hdxB_

Fold library id	PDB Header	Molecule	Title
c2hdxB_	PDB header: signaling protein	Chain: B: PDB Molecule: sh2-b ph domain containing signaling mediator 1	PDBTitle: crystal structure of the src homology-2 domain of sh2-b in2 complex with jak2 ptyr813 phosphopeptide

Links to external resources
Added to library: Wed Jan 9 22:53:00 2013

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence Q P L S G Y P W F H G M L S R L K A A Q L V L E G G T G S H G V F L V R Q S E T R R G E C V L T F N F Q G K A K H L R L S L N A A G Q C R V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G S T T B
S
T T G G G G T T
S S S T T T T
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . .

Sequence Q H L H F Q S I F D M L E H F R V H P I P L E S S D V V L V S Y V P S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S S S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	Q	P	L	S	G	Y	P	W	F	H	G	M	L	S	R	L	K	A	A	Q	L	V	L	E	G	G	T	G	S	H	G	V	F	L	V	R	Q	S	E	T	R	R	G	E	C	V	L	T	F	N	F	Q	G	K	A	K	H	L	R	L	S	L	N	A	A	G	Q	C	R	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			G	G	G	S	T	T	B			S												T	T	G	G	G	G	T	T								S	S	S	T	T									T	T											T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.
Sequence	Q	H	L	H	F	Q	S	I	F	D	M	L	E	H	F	R	V	H	P	I	P	L	E	S	S	D	V	V	L	V	S	Y	V	P	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T				S	S											S