Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	I	K	K	I	G	V	L	T	S	G	G	D	A	P	G	M	N	A	A	I	R	G	V	V	R	S	A	L	T	E	G	L	E	V	M	G	I	Y	D	G	Y	L	G	L	Y	E	D	R	M	V	Q	L	D	R	Y	S	V	S	D
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		M	I	N	R	G	G	T	F	L	G	S	A	R	F	P	E	F	R	D	E	N	I	R	A	V	A	I	E	N	L	K	K	R	G	I	D	A	L	V	V	I	G	G	D	G	S	Y	M	G	A	M	R	L	T	E	M	G	F	P	C
Secondary structure
SS confidence
Disorder															?			?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		I	G	L	P	G	T	I	D	N	D	I	K	G	T	D	Y	T	I	G	F	F	T	A	L	S	T	V	V	E	A	I	D	R	L	R	D	T	S	S	S	H	Q	R	I	S	V	V	E	V	M	G	R	Y	C	G	D	L	T	L	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	A	I	A	G	G	C	E	F	V	V	V	P	E	V	E	F	S	R	E	D	L	V	N	E	I	K	A	G	I	A	K	G	K	K	H	A	I	V	A	I	T	E	H	M	C	D	V	D	E	L	A	H	F	I	E	K	E	T	G
Secondary structure
SS confidence
Disorder																																	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		R	E	T	R	A	T	V	L	G	H	I	Q	R	G	G	S	P	V	P	Y	D	R	I	L	A	S	R	M	G	A	Y	A	I	D	L	L	L	A	G	Y	G	G	R	C	V	G	I	Q	N	E	Q	L	V	H	H	D	I	I	D	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320
Sequence		I	E	N	M	K	R	P	F	K	G	D	W	L	D	C	A	K	K	L	Y
Secondary structure
SS confidence
Disorder			?																	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1pfk chain A Region: 1 - 320 Aligned: 320 Modelled: 320 Confidence: 100.0% Identity: 100% Fold: Phosphofructokinase Superfamily: Phosphofructokinase Family: Phosphofructokinase Phyre2 PDB 4pfk chain A Region: 2 - 319 Aligned: 317 Modelled: 318 Confidence: 100.0% Identity: 55% Fold: Phosphofructokinase Superfamily: Phosphofructokinase Family: Phosphofructokinase Phyre2 PDB 1zxx chain A Region: 2 - 319 Aligned: 317 Modelled: 318 Confidence: 100.0% Identity: 49% PDB header:transferase Chain: A: PDB Molecule:6-phosphofructokinase; PDBTitle: the crystal structure of phosphofructokinase from lactobacillus2 delbrueckii Phyre2 PDB 3o8o chain C Region: 3 - 305 Aligned: 303 Modelled: 303 Confidence: 100.0% Identity: 39% PDB header:transferase Chain: C: PDB Molecule:6-phosphofructokinase subunit alpha; PDBTitle: structure of phosphofructokinase from saccharomyces cerevisiae Phyre2 PDB 3opy chain H Region: 2 - 305 Aligned: 303 Modelled: 304 Confidence: 100.0% Identity: 39% PDB header:transferase Chain: H: PDB Molecule:6-phosphofructo-1-kinase beta-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state Phyre2 PDB 3o8o chain B Region: 2 - 305 Aligned: 304 Modelled: 304 Confidence: 100.0% Identity: 38% PDB header:transferase Chain: B: PDB Molecule:6-phosphofructokinase subunit beta; PDBTitle: structure of phosphofructokinase from saccharomyces cerevisiae Phyre2 PDB 3opy chain B Region: 2 - 305 Aligned: 303 Modelled: 304 Confidence: 100.0% Identity: 39% PDB header:transferase Chain: B: PDB Molecule:6-phosphofructo-1-kinase beta-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state Phyre2 PDB 3opy chain G Region: 2 - 305 Aligned: 304 Modelled: 304 Confidence: 100.0% Identity: 40% PDB header:transferase Chain: G: PDB Molecule:6-phosphofructo-1-kinase alpha-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state Phyre2 PDB 3o8n chain A Region: 3 - 305 Aligned: 303 Modelled: 303 Confidence: 100.0% Identity: 42% PDB header:transferase Chain: A: PDB Molecule:6-phosphofructokinase, muscle type; PDBTitle: structure of phosphofructokinase from rabbit skeletal muscle Phyre2 PDB 3opy chain E Region: 2 - 305 Aligned: 304 Modelled: 304 Confidence: 100.0% Identity: 42% PDB header:transferase Chain: E: PDB Molecule:6-phosphofructo-1-kinase alpha-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state Phyre2 PDB 3k2q chain A Region: 2 - 314 Aligned: 306 Modelled: 313 Confidence: 100.0% Identity: 24% PDB header:transferase Chain: A: PDB Molecule:pyrophosphate-dependent phosphofructokinase; PDBTitle: crystal structure of pyrophosphate-dependent2 phosphofructokinase from marinobacter aquaeolei, northeast3 structural genomics consortium target mqr88 Phyre2 PDB 2hig chain A Region: 4 - 319 Aligned: 310 Modelled: 316 Confidence: 100.0% Identity: 26% PDB header:transferase Chain: A: PDB Molecule:6-phospho-1-fructokinase; PDBTitle: crystal structure of phosphofructokinase apoenzyme from trypanosoma2 brucei. Phyre2 PDB 2f48 chain A domain 1 Region: 2 - 306 Aligned: 304 Modelled: 305 Confidence: 100.0% Identity: 26% Fold: Phosphofructokinase Superfamily: Phosphofructokinase Family: Phosphofructokinase Phyre2 PDB 3h5o chain B Region: 3 - 278 Aligned: 233 Modelled: 239 Confidence: 97.5% Identity: 14% PDB header:transcription regulator Chain: B: PDB Molecule:transcriptional regulator gntr; PDBTitle: the crystal structure of transcription regulator gntr from2 chromobacterium violaceum Phyre2 PDB 2an1 chain D Region: 54 - 169 Aligned: 97 Modelled: 116 Confidence: 96.1% Identity: 20% PDB header:transferase Chain: D: PDB Molecule:putative kinase; PDBTitle: structural genomics, the crystal structure of a putative kinase from2 salmonella typhimurim lt2 Phyre2 PDB 1u0t chain A Region: 81 - 149 Aligned: 68 Modelled: 69 Confidence: 96.0% Identity: 19% Fold: NAD kinase/diacylglycerol kinase-like Superfamily: NAD kinase/diacylglycerol kinase-like Family: NAD kinase-like Phyre2 PDB 2nzu chain G domain 1 Region: 2 - 278 Aligned: 235 Modelled: 235 Confidence: 96.0% Identity: 14% Fold: Periplasmic binding protein-like I Superfamily: Periplasmic binding protein-like I Family: L-arabinose binding protein-like Phyre2 PDB 1yt5 chain A Region: 94 - 169 Aligned: 66 Modelled: 66 Confidence: 95.6% Identity: 27% PDB header:transferase Chain: A: PDB Molecule:inorganic polyphosphate/atp-nad kinase; PDBTitle: crystal structure of nad kinase from thermotoga maritima Phyre2 PDB 1z0s chain A domain 1 Region: 78 - 123 Aligned: 46 Modelled: 46 Confidence: 95.6% Identity: 24% Fold: NAD kinase/diacylglycerol kinase-like Superfamily: NAD kinase/diacylglycerol kinase-like Family: NAD kinase-like Phyre2 PDB 1z0z chain C Region: 78 - 123 Aligned: 46 Modelled: 46 Confidence: 95.5% Identity: 24% PDB header:transferase Chain: C: PDB Molecule:probable inorganic polyphosphate/atp-nad kinase; PDBTitle: crystal structure of a nad kinase from archaeoglobus2 fulgidus in complex with nad Phyre2 1 d1pfka_ 2 d4pfka_ 3 c1zxxA_ 4 c3o8oC_ 5 c3opyH_ 6 c3o8oB_ 7 c3opyB_ 8 c3opyG_ 9 c3o8nA_ 10 c3opyE_ 11 c3k2qA_ 12 c2higA_ 13 d2f48a1 14 c3h5oB_ 15 c2an1D_ 16 d1u0ta_ 17 d2nzug1 18 c1yt5A_ 19 d1z0sa1 20 c1z0zC_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1pfka_ 100.0 100 Fold:Phosphofructokinase Superfamily:Phosphofructokinase Family:Phosphofructokinase 2 d4pfka_ 100.0 55 Fold:Phosphofructokinase Superfamily:Phosphofructokinase Family:Phosphofructokinase 3 c1zxxA_ 100.0 49 PDB header:transferase Chain: A: PDB Molecule:6-phosphofructokinase; PDBTitle: the crystal structure of phosphofructokinase from lactobacillus2 delbrueckii 4 c3o8oC_ 100.0 39 PDB header:transferase Chain: C: PDB Molecule:6-phosphofructokinase subunit alpha; PDBTitle: structure of phosphofructokinase from saccharomyces cerevisiae 5 c3opyH_ 100.0 39 PDB header:transferase Chain: H: PDB Molecule:6-phosphofructo-1-kinase beta-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state 6 c3o8oB_ 100.0 38 PDB header:transferase Chain: B: PDB Molecule:6-phosphofructokinase subunit beta; PDBTitle: structure of phosphofructokinase from saccharomyces cerevisiae 7 c3opyB_ 100.0 39 PDB header:transferase Chain: B: PDB Molecule:6-phosphofructo-1-kinase beta-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state 8 c3opyG_ 100.0 40 PDB header:transferase Chain: G: PDB Molecule:6-phosphofructo-1-kinase alpha-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state 9 c3o8nA_ 100.0 42 PDB header:transferase Chain: A: PDB Molecule:6-phosphofructokinase, muscle type; PDBTitle: structure of phosphofructokinase from rabbit skeletal muscle 10 c3opyE_ 100.0 42 PDB header:transferase Chain: E: PDB Molecule:6-phosphofructo-1-kinase alpha-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state 11 c3k2qA_ 100.0 24 PDB header:transferase Chain: A: PDB Molecule:pyrophosphate-dependent phosphofructokinase; PDBTitle: crystal structure of pyrophosphate-dependent2 phosphofructokinase from marinobacter aquaeolei, northeast3 structural genomics consortium target mqr88 12 c2higA_ 100.0 26 PDB header:transferase Chain: A: PDB Molecule:6-phospho-1-fructokinase; PDBTitle: crystal structure of phosphofructokinase apoenzyme from trypanosoma2 brucei. 13 d2f48a1 100.0 26 Fold:Phosphofructokinase Superfamily:Phosphofructokinase Family:Phosphofructokinase 14 c3h5oB_ 97.5 14 PDB header:transcription regulator Chain: B: PDB Molecule:transcriptional regulator gntr; PDBTitle: the crystal structure of transcription regulator gntr from2 chromobacterium violaceum 15 c2an1D_ 96.1 20 PDB header:transferase Chain: D: PDB Molecule:putative kinase; PDBTitle: structural genomics, the crystal structure of a putative kinase from2 salmonella typhimurim lt2 16 d1u0ta_ 96.0 19 Fold:NAD kinase/diacylglycerol kinase-like Superfamily:NAD kinase/diacylglycerol kinase-like Family:NAD kinase-like 17 d2nzug1 96.0 14 Fold:Periplasmic binding protein-like I Superfamily:Periplasmic binding protein-like I Family:L-arabinose binding protein-like 18 c1yt5A_ 95.6 27 PDB header:transferase Chain: A: PDB Molecule:inorganic polyphosphate/atp-nad kinase; PDBTitle: crystal structure of nad kinase from thermotoga maritima 19 d1z0sa1 95.6 24 Fold:NAD kinase/diacylglycerol kinase-like Superfamily:NAD kinase/diacylglycerol kinase-like Family:NAD kinase-like 20 c1z0zC_ 95.5 24 PDB header:transferase Chain: C: PDB Molecule:probable inorganic polyphosphate/atp-nad kinase; PDBTitle: crystal structure of a nad kinase from archaeoglobus2 fulgidus in complex with nad 21 c3pfnB_ not modelled 95.4 19 PDB header:transferase Chain: B: PDB Molecule:nad kinase; PDBTitle: crystal structure of human nad kinase 22 c2rgyA_ not modelled 95.1 14 PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator, laci family; PDBTitle: crystal structure of transcriptional regulator of laci family from2 burkhoderia phymatum 23 c1xahA_ not modelled 94.8 21 PDB header:lyase Chain: A: PDB Molecule:3-dehydroquinate synthase; PDBTitle: crystal structure of staphlyococcus aureus 3-dehydroquinate2 synthase (dhqs) in complex with zn2+ and nad+ 24 c3hl0B_ not modelled 94.7 19 PDB header:oxidoreductase Chain: B: PDB Molecule:maleylacetate reductase; PDBTitle: crystal structure of maleylacetate reductase from agrobacterium2 tumefaciens 25 d1dbqa_ not modelled 94.7 13 Fold:Periplasmic binding protein-like I Superfamily:Periplasmic binding protein-like I Family:L-arabinose binding protein-like 26 c2gpwC_ not modelled 94.5 19 PDB header:ligase Chain: C: PDB Molecule:biotin carboxylase; PDBTitle: crystal structure of the biotin carboxylase subunit, f363a2 mutant, of acetyl-coa carboxylase from escherichia coli. 27 c3okfA_ not modelled 94.4 14 PDB header:lyase Chain: A: PDB Molecule:3-dehydroquinate synthase; PDBTitle: 2.5 angstrom resolution crystal structure of 3-dehydroquinate synthase2 (arob) from vibrio cholerae 28 c2qh8A_ not modelled 94.3 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of conserved domain protein from vibrio2 cholerae o1 biovar eltor str. n16961 29 c3clhA_ not modelled 94.2 14 PDB header:lyase Chain: A: PDB Molecule:3-dehydroquinate synthase; PDBTitle: crystal structure of 3-dehydroquinate synthase (dhqs)from2 helicobacter pylori 30 c2i2aA_ not modelled 94.1 20 PDB header:transferase Chain: A: PDB Molecule:probable inorganic polyphosphate/atp-nad kinase 1; PDBTitle: crystal structure of lmnadk1 from listeria monocytogenes 31 d1vlja_ not modelled 94.1 14 Fold:Dehydroquinate synthase-like Superfamily:Dehydroquinate synthase-like Family:Iron-containing alcohol dehydrogenase 32 c3jzdA_ not modelled 94.1 21 PDB header:oxidoreductase Chain: A: PDB Molecule:iron-containing alcohol dehydrogenase; PDBTitle: crystal structure of putative alcohol dehedrogenase (yp_298327.1) from2 ralstonia eutropha jmp134 at 2.10 a resolution 33 d1rrma_ not modelled 93.9 14 Fold:Dehydroquinate synthase-like Superfamily:Dehydroquinate synthase-like Family:Iron-containing alcohol dehydrogenase 34 d2bona1 not modelled 93.9 23 Fold:NAD kinase/diacylglycerol kinase-like Superfamily:NAD kinase/diacylglycerol kinase-like Family:Diacylglycerol kinase-like 35 c3iv7B_ not modelled 93.8 21 PDB header:oxidoreductase Chain: B: PDB Molecule:alcohol dehydrogenase iv; PDBTitle: crystal structure of iron-containing alcohol dehydrogenase2 (np_602249.1) from corynebacterium glutamicum atcc 13032 kitasato at3 2.07 a resolution 36 d1jq5a_ not modelled 93.8 12 Fold:Dehydroquinate synthase-like Superfamily:Dehydroquinate synthase-like Family:Iron-containing alcohol dehydrogenase 37 c3uhjE_ not modelled 93.7 17 PDB header:oxidoreductase Chain: E: PDB Molecule:probable glycerol dehydrogenase; PDBTitle: crystal structure of a probable glycerol dehydrogenase from2 sinorhizobium meliloti 1021 38 d2jgra1 not modelled 93.7 23 Fold:NAD kinase/diacylglycerol kinase-like Superfamily:NAD kinase/diacylglycerol kinase-like Family:Diacylglycerol kinase-like 39 c3qk7C_ not modelled 93.6 17 PDB header:transcription regulator Chain: C: PDB Molecule:transcriptional regulators; PDBTitle: crystal structure of putative transcriptional regulator from yersinia2 pestis biovar microtus str. 91001 40 c3ox4D_ not modelled 93.4 14 PDB header:oxidoreductase Chain: D: PDB Molecule:alcohol dehydrogenase 2; PDBTitle: structures of iron-dependent alcohol dehydrogenase 2 from zymomonas2 mobilis zm4 complexed with nad cofactor 41 c3hcwB_ not modelled 93.4 13 PDB header:rna binding protein Chain: B: PDB Molecule:maltose operon transcriptional repressor; PDBTitle: crystal structure of probable maltose operon transcriptional repressor2 malr from staphylococcus areus 42 d1o2da_ not modelled 93.4 21 Fold:Dehydroquinate synthase-like Superfamily:Dehydroquinate synthase-like Family:Iron-containing alcohol dehydrogenase 43 d1oj7a_ not modelled 93.3 12 Fold:Dehydroquinate synthase-like Superfamily:Dehydroquinate synthase-like Family:Iron-containing alcohol dehydrogenase 44 c2dlnA_ not modelled 93.3 24 PDB header:ligase(peptidoglycan synthesis) Chain: A: PDB Molecule:d-alanine--d-alanine ligase; PDBTitle: vancomycin resistance: structure of d-alanine:d-alanine2 ligase at 2.3 angstroms resolution 45 c3afoB_ not modelled 93.3 31 PDB header:transferase Chain: B: PDB Molecule:nadh kinase pos5; PDBTitle: crystal structure of yeast nadh kinase complexed with nadh 46 d1tlfa_ not modelled 93.2 14 Fold:Periplasmic binding protein-like I Superfamily:Periplasmic binding protein-like I Family:L-arabinose binding protein-like 47 c2gruB_ not modelled 93.0 27 PDB header:lyase Chain: B: PDB Molecule:2-deoxy-scyllo-inosose synthase; PDBTitle: crystal structure of 2-deoxy-scyllo-inosose synthase2 complexed with carbaglucose-6-phosphate, nad+ and co2+ 48 c2qk4A_ not modelled 92.8 17 PDB header:ligase Chain: A: PDB Molecule:trifunctional purine biosynthetic protein adenosine-3; PDBTitle: human glycinamide ribonucleotide synthetase 49 c3bfjK_ not modelled 92.8 14 PDB header:oxidoreductase Chain: K: PDB Molecule:1,3-propanediol oxidoreductase; PDBTitle: crystal structure analysis of 1,3-propanediol oxidoreductase 50 c3g85A_ not modelled 92.8 10 PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator (laci family); PDBTitle: crystal structure of laci family transcription regulator from2 clostridium acetobutylicum 51 d2p1ra1 not modelled 92.7 18 Fold:NAD kinase/diacylglycerol kinase-like Superfamily:NAD kinase/diacylglycerol kinase-like Family:Diacylglycerol kinase-like 52 d1ujna_ not modelled 92.3 20 Fold:Dehydroquinate synthase-like Superfamily:Dehydroquinate synthase-like Family:Dehydroquinate synthase, DHQS 53 c3g8cB_ not modelled 92.3 19 PDB header:ligase Chain: B: PDB Molecule:biotin carboxylase; PDBTitle: crystal stucture of biotin carboxylase in complex with2 biotin, bicarbonate, adp and mg ion 54 c1ta9A_ not modelled 92.0 15 PDB header:oxidoreductase Chain: A: PDB Molecule:glycerol dehydrogenase; PDBTitle: crystal structure of glycerol dehydrogenase from schizosaccharomyces2 pombe 55 c3rotA_ not modelled 91.8 12 PDB header:transport protein Chain: A: PDB Molecule:abc sugar transporter, periplasmic sugar binding protein; PDBTitle: crystal structure of abc sugar transporter (periplasmic sugar binding2 protein) from legionella pneumophila 56 c2bonB_ not modelled 91.7 24 PDB header:transferase Chain: B: PDB Molecule:lipid kinase; PDBTitle: structure of an escherichia coli lipid kinase (yegs) 57 c1m6vE_ not modelled 91.1 24 PDB header:ligase Chain: E: PDB Molecule:carbamoyl phosphate synthetase large chain; PDBTitle: crystal structure of the g359f (small subunit) point mutant of2 carbamoyl phosphate synthetase 58 c2qv7A_ not modelled 90.9 16 PDB header:transferase Chain: A: PDB Molecule:diacylglycerol kinase dgkb; PDBTitle: crystal structure of diacylglycerol kinase dgkb in complex with adp2 and mg 59 c1ulzA_ not modelled 90.7 23 PDB header:ligase Chain: A: PDB Molecule:pyruvate carboxylase n-terminal domain; PDBTitle: crystal structure of the biotin carboxylase subunit of pyruvate2 carboxylase 60 d1sg6a_ not modelled 90.6 14 Fold:Dehydroquinate synthase-like Superfamily:Dehydroquinate synthase-like Family:Dehydroquinate synthase, DHQS 61 c3ma0A_ not modelled 90.3 15 PDB header:sugar binding protein Chain: A: PDB Molecule:d-xylose-binding periplasmic protein; PDBTitle: closed liganded crystal structure of xylose binding protein from2 escherichia coli 62 c3ouzA_ not modelled 90.3 16 PDB header:ligase Chain: A: PDB Molecule:biotin carboxylase; PDBTitle: crystal structure of biotin carboxylase-adp complex from campylobacter2 jejuni 63 d2qv7a1 not modelled 89.7 16 Fold:NAD kinase/diacylglycerol kinase-like Superfamily:NAD kinase/diacylglycerol kinase-like Family:Diacylglycerol kinase-like 64 c3rf7A_ not modelled 89.5 12 PDB header:oxidoreductase Chain: A: PDB Molecule:iron-containing alcohol dehydrogenase; PDBTitle: crystal structure of an iron-containing alcohol dehydrogenase2 (sden_2133) from shewanella denitrificans os-217 at 2.12 a resolution 65 c3s40C_ not modelled 88.9 20 PDB header:transferase Chain: C: PDB Molecule:diacylglycerol kinase; PDBTitle: the crystal structure of a diacylglycerol kinases from bacillus2 anthracis str. sterne 66 d4pgaa_ not modelled 88.8 16 Fold:Glutaminase/Asparaginase Superfamily:Glutaminase/Asparaginase Family:Glutaminase/Asparaginase 67 c3brsA_ not modelled 87.9 13 PDB header:transport protein Chain: A: PDB Molecule:periplasmic binding protein/laci transcriptional regulator; PDBTitle: crystal structure of sugar transporter from clostridium2 phytofermentans 68 c3mizB_ not modelled 87.7 17 PDB header:transcription regulator Chain: B: PDB Molecule:putative transcriptional regulator protein, laci PDBTitle: crystal structure of a putative transcriptional regulator2 protein, lacl family from rhizobium etli 69 c3bblA_ not modelled 87.7 15 PDB header:regulatory protein Chain: A: PDB Molecule:regulatory protein of laci family; PDBTitle: crystal structure of a regulatory protein of laci family from2 chloroflexus aggregans 70 c3ksmA_ not modelled 86.5 12 PDB header:transport protein Chain: A: PDB Molecule:abc-type sugar transport system, periplasmic component; PDBTitle: crystal structure of abc-type sugar transport system, periplasmic2 component from hahella chejuensis 71 d1tjya_ not modelled 83.5 13 Fold:Periplasmic binding protein-like I Superfamily:Periplasmic binding protein-like I Family:L-arabinose binding protein-like 72 c3ce9A_ not modelled 82.5 16 PDB header:oxidoreductase Chain: A: PDB Molecule:glycerol dehydrogenase; PDBTitle: crystal structure of glycerol dehydrogenase (np_348253.1) from2 clostridium acetobutylicum at 2.37 a resolution 73 c3lftA_ not modelled 82.5 24 PDB header:structure genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: the crystal structure of the abc domain in complex with l-trp from2 streptococcus pneumonia to 1.35a 74 d1a9xa3 not modelled 82.5 24 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 75 c3n8hA_ not modelled 82.1 20 PDB header:ligase Chain: A: PDB Molecule:pantothenate synthetase; PDBTitle: crystal structure of pantoate-beta-alanine ligase from francisella2 tularensis 76 d1y81a1 not modelled 81.9 18 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 77 c3l6uA_ not modelled 81.4 14 PDB header:transport protein Chain: A: PDB Molecule:abc-type sugar transport system periplasmic PDBTitle: crystal structure of abc-type sugar transport system,2 periplasmic component from exiguobacterium sibiricum 78 c3lp6D_ not modelled 79.2 19 PDB header:lyase Chain: D: PDB Molecule:phosphoribosylaminoimidazole carboxylase catalytic subunit; PDBTitle: crystal structure of rv3275c-e60a from mycobacterium tuberculosis at2 1.7a resolution 79 d1qcza_ not modelled 79.2 15 Fold:Flavodoxin-like Superfamily:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) Family:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) 80 c2h31A_ not modelled 77.8 16 PDB header:ligase, lyase Chain: A: PDB Molecule:multifunctional protein ade2; PDBTitle: crystal structure of human paics, a bifunctional carboxylase and2 synthetase in purine biosynthesis 81 d1u11a_ not modelled 77.7 19 Fold:Flavodoxin-like Superfamily:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) Family:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) 82 d8abpa_ not modelled 77.3 15 Fold:Periplasmic binding protein-like I Superfamily:Periplasmic binding protein-like I Family:L-arabinose binding protein-like 83 d1o4va_ not modelled 77.0 23 Fold:Flavodoxin-like Superfamily:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) Family:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) 84 c3gv0A_ not modelled 75.9 11 PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator, laci family; PDBTitle: crystal structure of laci family transcription regulator from2 agrobacterium tumefaciens 85 c2dzdB_ not modelled 74.8 27 PDB header:ligase Chain: B: PDB Molecule:pyruvate carboxylase; PDBTitle: crystal structure of the biotin carboxylase domain of2 pyruvate carboxylase 86 d1a9xa4 not modelled 74.5 18 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 87 c3k4hA_ not modelled 73.7 21 PDB header:transcription regulator Chain: A: PDB Molecule:putative transcriptional regulator; PDBTitle: crystal structure of putative transcriptional regulator laci from2 bacillus cereus subsp. cytotoxis nvh 391-98 88 c3o74A_ not modelled 73.7 15 PDB header:transcription Chain: A: PDB Molecule:fructose transport system repressor frur; PDBTitle: crystal structure of cra transcriptional dual regulator from2 pseudomonas putida 89 c3brqA_ not modelled 73.3 12 PDB header:transcription regulator Chain: A: PDB Molecule:hth-type transcriptional regulator ascg; PDBTitle: crystal structure of the escherichia coli transcriptional repressor2 ascg 90 c3jy6B_ not modelled 72.5 15 PDB header:transcription regulator Chain: B: PDB Molecule:transcriptional regulator, laci family; PDBTitle: crystal structure of laci transcriptional regulator from lactobacillus2 brevis 91 c3orsD_ not modelled 71.3 22 PDB header:isomerase,biosynthetic protein Chain: D: PDB Molecule:n5-carboxyaminoimidazole ribonucleotide mutase; PDBTitle: crystal structure of n5-carboxyaminoimidazole ribonucleotide mutase2 from staphylococcus aureus 92 c2vpqA_ not modelled 71.2 15 PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase; PDBTitle: crystal structure of biotin carboxylase from s. aureus2 complexed with amppnp 93 c3d8uA_ not modelled 69.6 8 PDB header:transcription regulator Chain: A: PDB Molecule:purr transcriptional regulator; PDBTitle: the crystal structure of a purr family transcriptional regulator from2 vibrio parahaemolyticus rimd 2210633 94 c3trhI_ not modelled 69.5 18 PDB header:lyase Chain: I: PDB Molecule:phosphoribosylaminoimidazole carboxylase PDBTitle: structure of a phosphoribosylaminoimidazole carboxylase catalytic2 subunit (pure) from coxiella burnetii 95 c3rggD_ not modelled 69.2 9 PDB header:lyase Chain: D: PDB Molecule:phosphoribosylaminoimidazole carboxylase, pure protein; PDBTitle: crystal structure of treponema denticola pure bound to air 96 c2h0aA_ not modelled 69.2 15 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator; PDBTitle: crystal structure of probable transcription regulator from2 thermus thermophilus 97 c2i80B_ not modelled 69.1 20 PDB header:ligase Chain: B: PDB Molecule:d-alanine-d-alanine ligase; PDBTitle: allosteric inhibition of staphylococcus aureus d-alanine:d-alanine2 ligase revealed by crystallographic studies 98 d1kq3a_ not modelled 67.7 18 Fold:Dehydroquinate synthase-like Superfamily:Dehydroquinate synthase-like Family:Iron-containing alcohol dehydrogenase 99 c3g1wB_ not modelled 67.6 11 PDB header:transport protein Chain: B: PDB Molecule:sugar abc transporter; PDBTitle: crystal structure of sugar abc transporter (sugar-binding protein)2 from bacillus halodurans 100 c3l49D_ not modelled 67.3 15 PDB header:transport protein Chain: D: PDB Molecule:abc sugar (ribose) transporter, periplasmic PDBTitle: crystal structure of abc sugar transporter subunit from2 rhodobacter sphaeroides 2.4.1 101 d1u0ma1 not modelled 65.4 24 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 102 c1kjjA_ not modelled 64.8 16 PDB header:transferase Chain: A: PDB Molecule:phosphoribosylglycinamide formyltransferase 2; PDBTitle: crystal structure of glycniamide ribonucleotide2 transformylase in complex with mg-atp-gamma-s 103 d2a84a1 not modelled 63.5 26 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) 104 c3d02A_ not modelled 63.3 15 PDB header:sugar binding protein Chain: A: PDB Molecule:putative laci-type transcriptional regulator; PDBTitle: crystal structure of periplasmic sugar-binding protein2 (yp_001338366.1) from klebsiella pneumoniae subsp. pneumoniae mgh3 78578 at 1.30 a resolution 105 d1zq1c2 not modelled 63.1 15 Fold:DCoH-like Superfamily:GAD domain-like Family:GAD domain 106 d1ihoa_ not modelled 61.4 21 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) 107 c2dwcB_ not modelled 59.9 17 PDB header:transferase Chain: B: PDB Molecule:433aa long hypothetical phosphoribosylglycinamide formyl PDBTitle: crystal structure of probable phosphoribosylglycinamide formyl2 transferase from pyrococcus horikoshii ot3 complexed with adp 108 c2ejcA_ not modelled 59.6 23 PDB header:ligase Chain: A: PDB Molecule:pantoate--beta-alanine ligase; PDBTitle: crystal structure of pantoate--beta-alanine ligase (panc)2 from thermotoga maritima 109 c2ioyB_ not modelled 58.8 18 PDB header:sugar binding protein Chain: B: PDB Molecule:periplasmic sugar-binding protein; PDBTitle: crystal structure of thermoanaerobacter tengcongensis2 ribose binding protein 110 d2fvya1 not modelled 58.7 14 Fold:Periplasmic binding protein-like I Superfamily:Periplasmic binding protein-like I Family:L-arabinose binding protein-like 111 d1guda_ not modelled 58.6 16 Fold:Periplasmic binding protein-like I Superfamily:Periplasmic binding protein-like I Family:L-arabinose binding protein-like 112 d1ybha2 not modelled 58.5 18 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase Pyr module 113 c3innB_ not modelled 57.9 21 PDB header:ligase Chain: B: PDB Molecule:pantothenate synthetase; PDBTitle: crystal structure of pantoate-beta-alanine-ligase in complex2 with atp at low occupancy at 2.1 a resolution 114 d1byka_ not modelled 57.1 22 Fold:Periplasmic binding protein-like I Superfamily:Periplasmic binding protein-like I Family:L-arabinose binding protein-like 115 c1hyuA_ not modelled 57.0 15 PDB header:oxidoreductase Chain: A: PDB Molecule:alkyl hydroperoxide reductase subunit f; PDBTitle: crystal structure of intact ahpf 116 d2dria_ not modelled 56.8 11 Fold:Periplasmic binding protein-like I Superfamily:Periplasmic binding protein-like I Family:L-arabinose binding protein-like 117 c1gsoA_ not modelled 56.1 23 PDB header:ligase Chain: A: PDB Molecule:protein (glycinamide ribonucleotide synthetase); PDBTitle: glycinamide ribonucleotide synthetase (gar-syn) from e.2 coli. 118 d1ozha2 not modelled 55.7 15 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase Pyr module 119 c3uk2B_ not modelled 53.9 24 PDB header:ligase Chain: B: PDB Molecule:pantothenate synthetase; PDBTitle: the structure of pantothenate synthetase from burkholderia2 thailandensis 120 d1xmpa_ not modelled 53.8 19 Fold:Flavodoxin-like Superfamily:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) Family:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0