Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP30855
DateThu Jan 5 11:46:34 GMT 2012
Unique Job ID75512627412270e3

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2c2aA_
Top template information
PDB header:transferase
Chain: A: PDB Molecule:sensor histidine kinase;
PDBTitle: structure of the entire cytoplasmic portion of a sensor2 histidine kinase protein
Confidence and coverage
Confidence:100.0% Coverage: 20%
235 residues ( 20% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
851 residues ( 71%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MKFLPYIFLLCCGLWSTISFADEDYIEYRGISSNNRVTLDPLRLSNKELRWLASKKNLVI
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   .........70.........80.........90.........100.........110.........120
Sequence  AVHKSQTATLLHTDSQQRVRGINADYLNLLKRALNIKLTLREYADHQKAMDALAEGEVDI
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   .........130.........140.........150.........160.........170.........180
Sequence  VLSHLVTSPPLNNDIAATKPLIITFPALVTTLHDSMRPLTSPKPVNIARVANYPPDEVIH
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   .........190.........200.........210.........220.........230.........240
Sequence  QSFPKATIISFTNLYQALASVSAGHNDYFIGSNIITSSMISRYFTHSLNVVKYYNSPRQY
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   .........250.........260.........270.........280.........290.........300
Sequence  NFFLTRKESVILNEVLNRFVDALTNEVRYEVSQNWLDTGNLAFLNKPLELTEHEKQWIKQ
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   .........310.........320.........330.........340.........350.........360
Sequence  HPNLKVLENPYSPPYSMTDENGSVRGVMGDILNIITLQTGLNFSPITVSHNIHAGTQLSP
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   .........370.........380.........390.........400.........410.........420
Sequence  GGWDIIPGAIYSEDRENNVLFAEAFITTPYVFVMQKAPDSEQTLKKGMKVAIPYYYELHS
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   .........430.........440.........450.........460.........470.........480
Sequence  QLKEMYPEVEWIQVDNASAAFHKVKEGELDALVATQLNSRYMIDHYYPNELYHFLIPGVP
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   .........490.........500.........510.........520.........530.........540
Sequence  NASLSFAFPRGEPELKDIINKALNAIPPSEVLRLTEKWIKMPNVTIDTWDLYSEQFYIVT
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   .........550.........560.........570.........580.........590.........600
Sequence  TLSVLLVGSSLLWGFYLLRSVRRRKVIQGDLENQISFRKALSDSLPNPTYVVNWQGNVIS
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   .........610.........620.........630.........640.........650.........660
Sequence  HNSAFEHYFTADYYKNAMLPLENSDSPFKDVFSNAHEVTAETKENRTIYTQVFEIDNGIE
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   .........670.........680.........690.........700.........710.........720
Sequence  KRCINHWHTLCNLPASDNAVYICGWQDITETRDLINALEVEKNKAIKATVAKSQFLATMS
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   .........730.........740.........750.........760.........770.........780
Sequence  HEIRTPISSIMGFLELLSGSGLSKEQRVEAISLAYATGQSLLGLIGEILDVDKIESGNYQ
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   .........790.........800.........810.........820.........830.........840
Sequence  LQPQWVDIPTLVQNTCHSFGAIAASKSIALSCSSTFPEHYLVKIDPQAFKQVLSNLLSNA
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   .........850.........860.........870.........880.........890.........900
Sequence  LKFTTEGAVKITTSLGHIDDNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQTSAGRQQTGS
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   .........910.........920.........930.........940.........950.........960
Sequence  GLGLMICKELIKNMQGDLSLESHPGIGTTFTITIPVEISQQVATVEAKAEQPITLPEKLS
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   .........970.........980.........990.........1000.........1010.........1020
Sequence  ILIADDHPTNRLLLKRQLNLLGYDVDEATDGVQALHKVSMQHYDLLITDVNMPNMDGFEL
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   .........1030.........1040.........1050.........1060.........1070.........1080
Sequence  TRKLREQNSSLPIWGLTANAQANEREKGLSCGMNLCLFKPLTLDVLKTHLSQLHQVAHIA
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   .........1090.........1100.........1110.........1120.........1130.........1140
Sequence  PQYRHLDIEALKNNTANDLQLMQEILMTFQHETHKDLPAAFQALEAGDNRTFHQCIHRIH
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   .........1150.........1160.........1170.........1180.........1190.......
Sequence  GAANILNLQKLINISHQLEITPVSDDSKPEILQLLNSVKEHIAELDQEIAVFCQKND
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2c2a chain A

3D model

Region: 685 - 935
Aligned: 235
Modelled: 251
Confidence: 100.0%
Identity: 27%
PDB header:transferase
Chain: A: PDB Molecule:sensor histidine kinase;
PDBTitle: structure of the entire cytoplasmic portion of a sensor2 histidine kinase protein

Phyre2

PDB 3a0r chain A

3D model

Region: 577 - 941
Aligned: 333
Modelled: 365
Confidence: 100.0%
Identity: 20%
PDB header:transferase
Chain: A: PDB Molecule:sensor protein;
PDBTitle: crystal structure of histidine kinase thka (tm1359) in complex with2 response regulator protein trra (tm1360)

Phyre2

PDB 3d36 chain B

3D model

Region: 707 - 937
Aligned: 217
Modelled: 231
Confidence: 100.0%
Identity: 23%
PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:sporulation kinase b;
PDBTitle: how to switch off a histidine kinase: crystal structure of2 geobacillus stearothermophilus kinb with the inhibitor sda

Phyre2

PDB 3d2r chain B

3D model

Region: 690 - 946
Aligned: 252
Modelled: 257
Confidence: 100.0%
Identity: 17%
PDB header:transferase
Chain: B: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 4;
PDBTitle: crystal structure of pyruvate dehydrogenase kinase isoform 4 in2 complex with adp

Phyre2

PDB 2q8f chain A

3D model

Region: 690 - 946
Aligned: 248
Modelled: 253
Confidence: 100.0%
Identity: 17%
PDB header:transferase
Chain: A: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 1;
PDBTitle: structure of pyruvate dehydrogenase kinase isoform 1

Phyre2

PDB 2bu8 chain A

3D model

Region: 691 - 947
Aligned: 248
Modelled: 257
Confidence: 100.0%
Identity: 17%
PDB header:transferase
Chain: A: PDB Molecule:pyruvate dehydrogenase kinase isoenzyme 2;
PDBTitle: crystal structures of human pyruvate dehydrogenase kinase 22 containing physiological and synthetic ligands

Phyre2

PDB 1y8o chain A

3D model

Region: 692 - 946
Aligned: 243
Modelled: 255
Confidence: 100.0%
Identity: 17%
PDB header:transferase
Chain: A: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 3;
PDBTitle: crystal structure of the pdk3-l2 complex

Phyre2

PDB 1gjv chain A

3D model

Region: 707 - 942
Aligned: 225
Modelled: 236
Confidence: 100.0%
Identity: 16%
PDB header:transferase
Chain: A: PDB Molecule:[3-methyl-2-oxobutanoate dehydrogenase
PDBTitle: branched-chain alpha-ketoacid dehydrogenase kinase (bck)2 complxed with atp-gamma-s

Phyre2

PDB 3mpl chain A

3D model

Region: 44 - 275
Aligned: 228
Modelled: 232
Confidence: 100.0%
Identity: 20%
PDB header:signaling protein
Chain: A: PDB Molecule:virulence sensor protein bvgs;
PDBTitle: crystal structure of bordetella pertussis bvgs vft2 domain (double2 mutant f375e/q461e)

Phyre2

PDB 3hv1 chain A

3D model

Region: 41 - 277
Aligned: 235
Modelled: 237
Confidence: 100.0%
Identity: 13%
PDB header:transport protein
Chain: A: PDB Molecule:polar amino acid abc uptake transporter substrate
PDBTitle: crystal structure of a polar amino acid abc uptake2 transporter substrate binding protein from streptococcus3 thermophilus

Phyre2

PDB 3kzg chain B

3D model

Region: 57 - 276
Aligned: 218
Modelled: 220
Confidence: 100.0%
Identity: 12%
PDB header:transport protein
Chain: B: PDB Molecule:arginine 3rd transport system periplasmic binding
PDBTitle: crystal structure of an arginine 3rd transport system2 periplasmic binding protein from legionella pneumophila

Phyre2

PDB 2ayx chain A

3D model

Region: 871 - 1074
Aligned: 204
Modelled: 204
Confidence: 100.0%
Identity: 33%
PDB header:transferase
Chain: A: PDB Molecule:sensor kinase protein rcsc;
PDBTitle: solution structure of the e.coli rcsc c-terminus (residues2 700-949) containing linker region and phosphoreceiver3 domain

Phyre2

PDB 3k4u chain A

3D model

Region: 55 - 280
Aligned: 223
Modelled: 219
Confidence: 100.0%
Identity: 15%
PDB header:transport protein
Chain: A: PDB Molecule:binding component of abc transporter;
PDBTitle: crystal structure of putative binding component of abc transporter2 from wolinella succinogenes dsm 1740 complexed with lysine

Phyre2

PDB 2yln chain A

3D model

Region: 50 - 277
Aligned: 224
Modelled: 226
Confidence: 100.0%
Identity: 12%
PDB header:transport protein
Chain: A: PDB Molecule:putative abc transporter, periplasmic binding protein,
PDBTitle: crystal structure of the l-cystine solute receptor of2 neisseria gonorrhoeae in the closed conformation

Phyre2

PDB 2a5s chain A domain 1

3D model

Region: 52 - 279
Aligned: 226
Modelled: 228
Confidence: 100.0%
Identity: 15%
Fold: Periplasmic binding protein-like II
Superfamily: Periplasmic binding protein-like II
Family: Phosphate binding protein-like

Phyre2

PDB 3g41 chain A

3D model

Region: 54 - 278
Aligned: 223
Modelled: 225
Confidence: 100.0%
Identity: 14%
PDB header:transport protein
Chain: A: PDB Molecule:amino acid abc transporter, periplasmic amino acid-binding
PDBTitle: the structure of cpn0482, the arginine binding protein from the2 periplasm of chlamydia pneumoniae

Phyre2

PDB 3r39 chain A

3D model

Region: 52 - 279
Aligned: 223
Modelled: 226
Confidence: 100.0%
Identity: 15%
PDB header:transport protein
Chain: A: PDB Molecule:putative periplasmic binding protein;
PDBTitle: crystal structure of periplasmic d-alanine abc transporter from2 salmonella enterica

Phyre2

PDB 2vha chain B

3D model

Region: 43 - 316
Aligned: 263
Modelled: 267
Confidence: 100.0%
Identity: 15%
PDB header:transport protein
Chain: B: PDB Molecule:periplasmic binding transport protein;
PDBTitle: debp

Phyre2

PDB 3i6v chain A

3D model

Region: 57 - 278
Aligned: 212
Modelled: 221
Confidence: 100.0%
Identity: 11%
PDB header:transport protein
Chain: A: PDB Molecule:periplasmic his/glu/gln/arg/opine family-binding protein;
PDBTitle: crystal structure of a periplasmic his/glu/gln/arg/opine family-2 binding protein from silicibacter pomeroyi in complex with lysine

Phyre2

PDB 2c2a chain A domain 2

3D model

Region: 780 - 938
Aligned: 151
Modelled: 159
Confidence: 100.0%
Identity: 26%
Fold: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family: Histidine kinase

Phyre2

PDB 1s8n chain A

3D model

Region: 958 - 1144
Aligned: 186
Modelled: 186
Confidence: 99.9%
Identity: 23%
Fold: Flavodoxin-like
Superfamily: CheY-like
Family: CheY-related

Phyre2

PDB 3myf chain B

3D model

Region: 1082 - 1195
Aligned: 114
Modelled: 111
Confidence: 99.5%
Identity: 12%
PDB header:transferase
Chain: B: PDB Molecule:sensor protein;
PDBTitle: the crystal structure of the hpt domain from the hpt sensor hybrid2 histidine kinase from shewanella to 1.80a

Phyre2

PDB 1yvi chain A domain 1

3D model

Region: 1092 - 1196
Aligned: 104
Modelled: 104
Confidence: 99.3%
Identity: 14%
Fold: Four-helical up-and-down bundle
Superfamily: Histidine-containing phosphotransfer domain, HPT domain
Family: Phosphorelay protein-like

Phyre2
1

c2c2aA_
2

c3a0rA_
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c3d36B_
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c3d2rB_
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c2q8fA_
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c2bu8A_
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c1y8oA_
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c1gjvA_
9

c3mplA_
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c3hv1A_
11

c3kzgB_
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c2ayxA_
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c3k4uA_
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c2ylnA_
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d2a5sa1
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c3g41A_
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c3r39A_
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c2vhaB_
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c3i6vA_
20

d2c2aa2
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d1s8na_
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c3myfB_
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d1yvia1
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2c2aA_



100.0 27 PDB header:transferase
Chain: A: PDB Molecule:sensor histidine kinase;
PDBTitle: structure of the entire cytoplasmic portion of a sensor2 histidine kinase protein
2c3a0rA_



100.0 20 PDB header:transferase
Chain: A: PDB Molecule:sensor protein;
PDBTitle: crystal structure of histidine kinase thka (tm1359) in complex with2 response regulator protein trra (tm1360)
3c3d36B_



100.0 23 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:sporulation kinase b;
PDBTitle: how to switch off a histidine kinase: crystal structure of2 geobacillus stearothermophilus kinb with the inhibitor sda
4c3d2rB_



100.0 17 PDB header:transferase
Chain: B: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 4;
PDBTitle: crystal structure of pyruvate dehydrogenase kinase isoform 4 in2 complex with adp
5c2q8fA_



100.0 17 PDB header:transferase
Chain: A: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 1;
PDBTitle: structure of pyruvate dehydrogenase kinase isoform 1
6c2bu8A_



100.0 17 PDB header:transferase
Chain: A: PDB Molecule:pyruvate dehydrogenase kinase isoenzyme 2;
PDBTitle: crystal structures of human pyruvate dehydrogenase kinase 22 containing physiological and synthetic ligands
7c1y8oA_



100.0 17 PDB header:transferase
Chain: A: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 3;
PDBTitle: crystal structure of the pdk3-l2 complex
8c1gjvA_



100.0 16 PDB header:transferase
Chain: A: PDB Molecule:[3-methyl-2-oxobutanoate dehydrogenase
PDBTitle: branched-chain alpha-ketoacid dehydrogenase kinase (bck)2 complxed with atp-gamma-s
9c3mplA_



100.0 20 PDB header:signaling protein
Chain: A: PDB Molecule:virulence sensor protein bvgs;
PDBTitle: crystal structure of bordetella pertussis bvgs vft2 domain (double2 mutant f375e/q461e)
10c3hv1A_



100.0 13 PDB header:transport protein
Chain: A: PDB Molecule:polar amino acid abc uptake transporter substrate
PDBTitle: crystal structure of a polar amino acid abc uptake2 transporter substrate binding protein from streptococcus3 thermophilus
11c3kzgB_



100.0 12 PDB header:transport protein
Chain: B: PDB Molecule:arginine 3rd transport system periplasmic binding
PDBTitle: crystal structure of an arginine 3rd transport system2 periplasmic binding protein from legionella pneumophila
12c2ayxA_



100.0 33 PDB header:transferase
Chain: A: PDB Molecule:sensor kinase protein rcsc;
PDBTitle: solution structure of the e.coli rcsc c-terminus (residues2 700-949) containing linker region and phosphoreceiver3 domain
13c3k4uA_



100.0 15 PDB header:transport protein
Chain: A: PDB Molecule:binding component of abc transporter;
PDBTitle: crystal structure of putative binding component of abc transporter2 from wolinella succinogenes dsm 1740 complexed with lysine
14c2ylnA_



100.0 12 PDB header:transport protein
Chain: A: PDB Molecule:putative abc transporter, periplasmic binding protein,
PDBTitle: crystal structure of the l-cystine solute receptor of2 neisseria gonorrhoeae in the closed conformation
15d2a5sa1



100.0 15 Fold:Periplasmic binding protein-like II
Superfamily:Periplasmic binding protein-like II
Family:Phosphate binding protein-like
16c3g41A_



100.0 14 PDB header:transport protein
Chain: A: PDB Molecule:amino acid abc transporter, periplasmic amino acid-binding
PDBTitle: the structure of cpn0482, the arginine binding protein from the2 periplasm of chlamydia pneumoniae
17c3r39A_



100.0 15 PDB header:transport protein
Chain: A: PDB Molecule:putative periplasmic binding protein;
PDBTitle: crystal structure of periplasmic d-alanine abc transporter from2 salmonella enterica
18c2vhaB_



100.0 15 PDB header:transport protein
Chain: B: PDB Molecule:periplasmic binding transport protein;
PDBTitle: debp
19c3i6vA_



100.0 11 PDB header:transport protein
Chain: A: PDB Molecule:periplasmic his/glu/gln/arg/opine family-binding protein;
PDBTitle: crystal structure of a periplasmic his/glu/gln/arg/opine family-2 binding protein from silicibacter pomeroyi in complex with lysine
20d2c2aa2



100.0 26 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family:Histidine kinase
21c1b3qA_



not modelled 100.0 17 PDB header:transferase
Chain: A: PDB Molecule:protein (chemotaxis protein chea);
PDBTitle: crystal structure of chea-289, a signal transducing histidine kinase
22c3h7mA_



not modelled 100.0 16 PDB header:transferase
Chain: A: PDB Molecule:sensor protein;
PDBTitle: crystal structure of a histidine kinase sensor domain with2 similarity to periplasmic binding proteins
23c2o1mB_



not modelled 100.0 15 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:probable amino-acid abc transporter
PDBTitle: crystal structure of the probable amino-acid abc2 transporter extracellular-binding protein ytmk from3 bacillus subtilis. northeast structural genomics4 consortium target sr572
24c2y7iB_



not modelled 100.0 11 PDB header:arginine-binding protein
Chain: B: PDB Molecule:stm4351;
PDBTitle: structural basis for high arginine specificity in salmonella2 typhimurium periplasmic binding protein stm4351.
25d1hsla_



not modelled 100.0 17 Fold:Periplasmic binding protein-like II
Superfamily:Periplasmic binding protein-like II
Family:Phosphate binding protein-like
26c2q2aD_



not modelled 100.0 14 PDB header:transport protein
Chain: D: PDB Molecule:artj;
PDBTitle: crystal structures of the arginine-, lysine-, histidine-2 binding protein artj from the thermophilic bacterium3 geobacillus stearothermophilus
27c3a0tA_



not modelled 100.0 22 PDB header:transferase
Chain: A: PDB Molecule:sensor protein;
PDBTitle: catalytic domain of histidine kinase thka (tm1359) in2 complex with adp and mg ion (trigonal)
28c2q89A_



not modelled 100.0 13 PDB header:transport protein
Chain: A: PDB Molecule:putative abc transporter amino acid-binding protein;
PDBTitle: crystal structure of ehub in complex with hydroxyectoine
29c2v25B_



not modelled 100.0 18 PDB header:receptor
Chain: B: PDB Molecule:major cell-binding factor;
PDBTitle: structure of the campylobacter jejuni antigen peb1a, an2 aspartate and glutamate receptor with bound aspartate
30c3kbrA_



not modelled 100.0 12 PDB header:lyase
Chain: A: PDB Molecule:cyclohexadienyl dehydratase;
PDBTitle: the crystal structure of cyclohexadienyl dehydratase precursor from2 pseudomonas aeruginosa pa01
31c2ieeB_



not modelled 100.0 14 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:probable abc transporter extracellular-binding
PDBTitle: crystal structure of yckb_bacsu from bacillus subtilis.2 northeast structural genomics consortium target sr574.
32d1lsta_



not modelled 100.0 14 Fold:Periplasmic binding protein-like II
Superfamily:Periplasmic binding protein-like II
Family:Phosphate binding protein-like
33c3delC_



not modelled 100.0 15 PDB header:protein binding, transport protein
Chain: C: PDB Molecule:arginine binding protein;
PDBTitle: the structure of ct381, the arginine binding protein from the2 periplasm chlamydia trachomatis
34d1gkza2



not modelled 100.0 20 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family:alpha-ketoacid dehydrogenase kinase, C-terminal domain
35d1wdna_



not modelled 99.9 14 Fold:Periplasmic binding protein-like II
Superfamily:Periplasmic binding protein-like II
Family:Phosphate binding protein-like
36d1bxda_



not modelled 99.9 20 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family:Histidine kinase
37d1id0a_



not modelled 99.9 20 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family:Histidine kinase
38d1jm6a2



not modelled 99.9 22 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family:alpha-ketoacid dehydrogenase kinase, C-terminal domain
39d1pb7a_



not modelled 99.9 15 Fold:Periplasmic binding protein-like II
Superfamily:Periplasmic binding protein-like II
Family:Phosphate binding protein-like
40c2rc9A_



not modelled 99.9 13 PDB header:membrane protein
Chain: A: PDB Molecule:glutamate [nmda] receptor subunit 3a;
PDBTitle: crystal structure of the nr3a ligand binding core complex with acpc at2 1.96 angstrom resolution
41c1xt8B_



not modelled 99.9 11 PDB header:transport protein
Chain: B: PDB Molecule:putative amino-acid transporter periplasmic solute-binding
PDBTitle: crystal structure of cysteine-binding protein from campylobacter2 jejuni at 2.0 a resolution
42c3jz3B_



not modelled 99.9 18 PDB header:transferase
Chain: B: PDB Molecule:sensor protein qsec;
PDBTitle: structure of the cytoplasmic segment of histidine kinase qsec
43c2yjpB_



not modelled 99.9 13 PDB header:transport protein
Chain: B: PDB Molecule:putative abc transporter, periplasmic binding protein,
PDBTitle: crystal structure of the solute receptors for l-cysteine of2 neisseria gonorrhoeae
44d1xt8a1



not modelled 99.9 11 Fold:Periplasmic binding protein-like II
Superfamily:Periplasmic binding protein-like II
Family:Phosphate binding protein-like
45c2ch4A_



not modelled 99.9 22 PDB header:transferase/chemotaxis
Chain: A: PDB Molecule:chemotaxis protein chea;
PDBTitle: complex between bacterial chemotaxis histidine kinase chea2 domains p4 and p5 and receptor-adaptor protein chew
46d1ysra1



not modelled 99.9 24 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family:Histidine kinase
47d1mqia_



not modelled 99.9 15 Fold:Periplasmic binding protein-like II
Superfamily:Periplasmic binding protein-like II
Family:Phosphate binding protein-like
48d1i58a_



not modelled 99.9 22 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family:Histidine kinase
49c1w25B_



not modelled 99.9 33 PDB header:signaling protein
Chain: B: PDB Molecule:stalked-cell differentiation controlling protein;
PDBTitle: response regulator pled in complex with c-digmp
50c3eq2A_



not modelled 99.9 30 PDB header:signaling protein
Chain: A: PDB Molecule:probable two-component response regulator;
PDBTitle: structure of hexagonal crystal form of pseudomonas2 aeruginosa rssb
51c3breA_



not modelled 99.9 21 PDB header:signaling protein
Chain: A: PDB Molecule:probable two-component response regulator;
PDBTitle: crystal structure of p.aeruginosa pa3702
52d1ii5a_



not modelled 99.9 16 Fold:Periplasmic binding protein-like II
Superfamily:Periplasmic binding protein-like II
Family:Phosphate binding protein-like
53c2pyyB_



not modelled 99.9 11 PDB header:transport protein
Chain: B: PDB Molecule:ionotropic glutamate receptor bacterial homologue;
PDBTitle: crystal structure of the glur0 ligand-binding core from nostoc2 punctiforme in complex with (l)-glutamate
54c2xx7B_



not modelled 99.9 15 PDB header:transport protein
Chain: B: PDB Molecule:glutamate receptor 2;
PDBTitle: crystal structure of 1-(4-(1-pyrrolidinylcarbonyl)phenyl)-3-2 (trifluoromethyl)-4,5,6,7-tetrahydro-1h-indazole in complex with3 the ligand binding domain of the rat glua2 receptor and glutamate4 at 2.2a resolution.
55d2ayxa1



not modelled 99.9 47 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
56c3i5aA_



not modelled 99.9 21 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator/ggdef domain protein;
PDBTitle: crystal structure of full-length wpsr from pseudomonas syringae
57c3n0rA_



not modelled 99.9 18 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator;
PDBTitle: structure of the phyr stress response regulator at 1.25 angstrom2 resolution
58d1peya_



not modelled 99.9 26 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
59d2pl1a1



not modelled 99.9 29 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
60d1jbea_



not modelled 99.9 35 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
61c1ny5A_



not modelled 99.9 21 PDB header:transcription
Chain: A: PDB Molecule:transcriptional regulator (ntrc family);
PDBTitle: crystal structure of sigm54 activator (aaa+ atpase) in the inactive2 state
62d1u0sy_



not modelled 99.9 25 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
63c3gt7A_



not modelled 99.9 31 PDB header:hydrolase
Chain: A: PDB Molecule:sensor protein;
PDBTitle: crystal structure of signal receiver domain of signal2 transduction histidine kinase from syntrophus3 aciditrophicus
64d1mvoa_



not modelled 99.9 32 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
65d1ny5a1



not modelled 99.9 21 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
66d1k66a_



not modelled 99.9 20 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
67c2zwmA_



not modelled 99.9 29 PDB header:transcription
Chain: A: PDB Molecule:transcriptional regulatory protein yycf;
PDBTitle: crystal structure of yycf receiver domain from bacillus2 subtilis
68d1qkka_



not modelled 99.9 25 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
69c3t6kB_



not modelled 99.9 31 PDB header:signaling protein
Chain: B: PDB Molecule:response regulator receiver;
PDBTitle: crystal structure of a hypothetical response regulator (caur_3799)2 from chloroflexus aurantiacus j-10-fl at 1.86 a resolution
70d1w25a1



not modelled 99.9 33 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
71d1s8na_



99.9 23 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
72c3cfyA_



not modelled 99.9 21 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative luxo repressor protein;
PDBTitle: crystal structure of signal receiver domain of putative luxo2 repressor protein from vibrio parahaemolyticus
73c2zayA_



not modelled 99.9 23 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator receiver protein;
PDBTitle: crystal structure of response regulator from desulfuromonas2 acetoxidans
74d1ys7a2



not modelled 99.9 30 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
75d2a9pa1



not modelled 99.9 29 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
76c3lteH_



not modelled 99.9 24 PDB header:transcription
Chain: H: PDB Molecule:response regulator;
PDBTitle: crystal structure of response regulator (signal receiver domain) from2 bermanella marisrubri
77d1dbwa_



not modelled 99.9 21 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
78c3r0jA_



not modelled 99.9 29 PDB header:dna binding protein
Chain: A: PDB Molecule:possible two component system response transcriptional
PDBTitle: structure of phop from mycobacterium tuberculosis
79c2rjnA_



not modelled 99.9 19 PDB header:hydrolase
Chain: A: PDB Molecule:response regulator receiver:metal-dependent
PDBTitle: crystal structure of an uncharacterized protein q2bku2 from2 neptuniibacter caesariensis
80c3gl9B_



not modelled 99.9 31 PDB header:signaling protein
Chain: B: PDB Molecule:response regulator;
PDBTitle: the structure of a histidine kinase-response regulator2 complex sheds light into two-component signaling and3 reveals a novel cis autophosphorylation mechanism
81d2r25b1



not modelled 99.9 35 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
82d1mb3a_



not modelled 99.9 23 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
83d1zh2a1



not modelled 99.9 29 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
84d1s50a1



not modelled 99.9 12 Fold:Periplasmic binding protein-like II
Superfamily:Periplasmic binding protein-like II
Family:Phosphate binding protein-like
85c3jteA_



not modelled 99.9 23 PDB header:protein binding
Chain: A: PDB Molecule:response regulator receiver protein;
PDBTitle: crystal structure of response regulator receiver domain2 protein from clostridium thermocellum
86d1yioa2



not modelled 99.9 24 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
87d1heya_



not modelled 99.9 33 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
88c3hv2B_



not modelled 99.9 27 PDB header:signaling protein
Chain: B: PDB Molecule:response regulator/hd domain protein;
PDBTitle: crystal structure of signal receiver domain of hd domain-2 containing protein from pseudomonas fluorescens pf-5
89d1kgsa2



not modelled 99.9 26 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
90c3nhzA_



not modelled 99.9 30 PDB header:dna binding protein
Chain: A: PDB Molecule:two component system transcriptional regulator mtra;
PDBTitle: structure of n-terminal domain of mtra
91d2hkja3



not modelled 99.9 20 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family:DNA gyrase/MutL, N-terminal domain
92c2qzjC_



not modelled 99.9 26 PDB header:transcription
Chain: C: PDB Molecule:two-component response regulator;
PDBTitle: crystal structure of a two-component response regulator from2 clostridium difficile
93c3h1gA_



not modelled 99.9 38 PDB header:signaling protein
Chain: A: PDB Molecule:chemotaxis protein chey homolog;
PDBTitle: crystal structure of chey mutant t84a of helicobacter pylori
94d1zgza1



not modelled 99.9 29 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
95c3cnbC_



not modelled 99.9 22 PDB header:dna binding protein
Chain: C: PDB Molecule:dna-binding response regulator, merr family;
PDBTitle: crystal structure of signal receiver domain of dna binding response2 regulator protein (merr) from colwellia psychrerythraea 34h
96d1p6qa_



not modelled 99.9 33 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
97c2qr3A_



not modelled 99.9 19 PDB header:transcription
Chain: A: PDB Molecule:two-component system response regulator;
PDBTitle: crystal structure of the n-terminal signal receiver domain of two-2 component system response regulator from bacteroides fragilis
98c3b2nA_



not modelled 99.9 19 PDB header:transcription
Chain: A: PDB Molecule:uncharacterized protein q99uf4;
PDBTitle: crystal structure of dna-binding response regulator, luxr family, from2 staphylococcus aureus
99d1zesa1



not modelled 99.9 23 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
100c3mmnA_



not modelled 99.9 28 PDB header:transferase
Chain: A: PDB Molecule:histidine kinase homolog;
PDBTitle: crystal structure of the receiver domain of the histidine kinase cki12 from arabidopsis thaliana complexed with mg2+
101d1krwa_



not modelled 99.9 23 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
102c3lufB_



not modelled 99.9 27 PDB header:signaling protein
Chain: B: PDB Molecule:two-component system response regulator/ggdef
PDBTitle: structure of probable two-component system response2 regulator/ggdef domain protein
103c3hdgE_



not modelled 99.9 23 PDB header:structural genomics, unknown function
Chain: E: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of the n-terminal domain of an2 uncharacterized protein (ws1339) from wolinella3 succinogenes
104c3dzdA_



not modelled 99.9 18 PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator (ntrc family);
PDBTitle: crystal structure of sigma54 activator ntrc4 in the inactive2 state
105c3c3mA_



not modelled 99.9 22 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator receiver protein;
PDBTitle: crystal structure of the n-terminal domain of response regulator2 receiver protein from methanoculleus marisnigri jr1
106c2jrlA_



not modelled 99.9 21 PDB header:transcription
Chain: A: PDB Molecule:transcriptional regulator (ntrc family);
PDBTitle: solution structure of the beryllofluoride-activated ntrc4 receiver2 domain dimer
107d1xhfa1



not modelled 99.9 31 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
108c3khtA_



not modelled 99.9 24 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator;
PDBTitle: crystal structure of response regulator from hahella chejuensis
109d1dcfa_



not modelled 99.9 24 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:Receiver domain of the ethylene receptor
110d1r62a_



not modelled 99.9 23 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Family:Histidine kinase
111c1ys7B_



not modelled 99.9 28 PDB header:transcription regulator
Chain: B: PDB Molecule:transcriptional regulatory protein prra;
PDBTitle: crystal structure of the response regulator protein prra comlexed with2 mg2+
112c3crnA_



not modelled 99.9 22 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator receiver domain protein, chey-like;
PDBTitle: crystal structure of response regulator receiver domain protein (chey-2 like) from methanospirillum hungatei jf-1
113c3cg4A_



not modelled 99.9 21 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:response regulator receiver domain protein (chey-like);
PDBTitle: crystal structure of response regulator receiver domain protein (chey-2 like) from methanospirillum hungatei jf-1
114c3eulB_



not modelled 99.9 27 PDB header:transcription
Chain: B: PDB Molecule:possible nitrate/nitrite response transcriptional
PDBTitle: structure of the signal receiver domain of the putative2 response regulator narl from mycobacterium tuberculosis
115d1a04a2



not modelled 99.9 29 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
116c3cu5B_



not modelled 99.9 25 PDB header:transcription regulator
Chain: B: PDB Molecule:two component transcriptional regulator, arac family;
PDBTitle: crystal structure of a two component transcriptional regulator arac2 from clostridium phytofermentans isdg
117c2qvgA_



not modelled 99.9 24 PDB header:transferase
Chain: A: PDB Molecule:two component response regulator;
PDBTitle: the crystal structure of a two-component response regulator2 from legionella pneumophila
118c3hdvB_



not modelled 99.9 23 PDB header:transcription regulator
Chain: B: PDB Molecule:response regulator;
PDBTitle: crystal structure of response regulator receiver protein from2 pseudomonas putida
119c2gwrA_



not modelled 99.9 28 PDB header:signaling protein
Chain: A: PDB Molecule:dna-binding response regulator mtra;
PDBTitle: crystal structure of the response regulator protein mtra from2 mycobacterium tuberculosis
120c2qxyB_



not modelled 99.9 21 PDB header:transcription
Chain: B: PDB Molecule:response regulator;
PDBTitle: crystal structure of a response regulator from thermotoga2 maritima

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0