PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2xx7B_

Fold library id	PDB Header	Molecule	Title
c2xx7B_	PDB header: transport protein	Chain: B: PDB Molecule: glutamate receptor 2;	PDBTitle: crystal structure of 1-(4-(1-pyrrolidinylcarbonyl)phenyl)-3-2 (trifluoromethyl)-4,5,6,7-tetrahydro-1h-indazole in complex with3 the ligand binding domain of the rat glua2 receptor and glutamate4 at 2.2a resolution.

Links to external resources
Added to library: Sat Apr 9 09:04:25 2011

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence G A N K T V V V T T I L E S P Y V M M K K N H E M L E G N E R Y E G Y C V D L A A E I A K H C G F K Y K L T I V G D G K Y G A R D A D T K I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
B T T T B
T T
T T
S G G G S T
T T
B
T T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence W N G M V G E L V Y G K A D I A I A P L T I T L V R E E V I D F S K P F M S L G I S I M I K K G T P I E S A E D L S K Q T E I A Y G T L D S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) B
T T S
S
S S
B
T T
S
S
T T
S
S T
S S S B T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence G S T K E F F R R S K I A V F D K M W T Y M R S A E P S V F V R T T A E G V A R V R K S K G K Y A Y L L E S T M N E Y I E Q R K P C D T M K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S
S S
B S S T T T S T S T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . .

Sequence V G G N L D S K G Y G I A T P K G S S L G N A V N L A V L K L S E Q G L L D K L K N K W W Y D K G E C G E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S
T T
T T T T T T T
S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	G	A	N	K	T	V	V	V	T	T	I	L	E	S	P	Y	V	M	M	K	K	N	H	E	M	L	E	G	N	E	R	Y	E	G	Y	C	V	D	L	A	A	E	I	A	K	H	C	G	F	K	Y	K	L	T	I	V	G	D	G	K	Y	G	A	R	D	A	D	T	K	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)													B	T	T	T	B				T	T		T	T			S	G	G	G			S														T									T	T						B		T	T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	W	N	G	M	V	G	E	L	V	Y	G	K	A	D	I	A	I	A	P	L	T	I	T	L	V	R	E	E	V	I	D	F	S	K	P	F	M	S	L	G	I	S	I	M	I	K	K	G	T	P	I	E	S	A	E	D	L	S	K	Q	T	E	I	A	Y	G	T	L	D	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	B									T	T	S		S				S	S		B							T	T					S		S											T	T		S			S						T		S	S	S					B	T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	G	S	T	K	E	F	F	R	R	S	K	I	A	V	F	D	K	M	W	T	Y	M	R	S	A	E	P	S	V	F	V	R	T	T	A	E	G	V	A	R	V	R	K	S	K	G	K	Y	A	Y	L	L	E	S	T	M	N	E	Y	I	E	Q	R	K	P	C	D	T	M	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S											S														S	S				B	S	S											T	T	T	S															T	S	T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.
Sequence	V	G	G	N	L	D	S	K	G	Y	G	I	A	T	P	K	G	S	S	L	G	N	A	V	N	L	A	V	L	K	L	S	E	Q	G	L	L	D	K	L	K	N	K	W	W	Y	D	K	G	E	C	G	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S			S											T	T		T															T	T										T	T	T	T		S