Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP76066
DateThu Jan 5 12:18:06 GMT 2012
Unique Job ID52fc389102ffcd0e

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1mkma1
Top template information
Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Transcriptional regulator IclR, N-terminal domain
Confidence and coverage
Confidence: 94.5% Coverage: 28%
57 residues ( 28% of your sequence) have been modelled with 94.5% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSSSQELRSNFYREKNLMETVFDALKAMGKATSIELAARLDISREEVLNELWELKKAGFV
Secondary structure 











SS confidence 



























































Disorder  ????






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   .........70.........80.........90.........100.........110.........120
Sequence  DKSAYTWRVADNNVQQEQPAQAELPEEITTATVAKISECDLTATIEQRGPQTADELATLF
Secondary structure 




























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Disorder 










??????????????




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?
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   .........130.........140.........150.........160.........170.........180
Sequence  GTTSRKVASTLAMAISKGRLIRVNQGGKFRYCIPGDNLPAEPKAASVSPLWLSASSSACH
Secondary structure 






























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Disorder 
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   .........190.........200...
Sequence  GVLIITVITPSPTKNSATKMPEN
Secondary structure 













SS confidence 






















Disorder 







???????????????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1mkm chain A domain 1

3D model

Region: 92 - 150
Aligned: 57
Modelled: 59
Confidence: 94.5%
Identity: 18%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: Transcriptional regulator IclR, N-terminal domain

Phyre2

PDB 2xro chain E

3D model

Region: 92 - 150
Aligned: 58
Modelled: 59
Confidence: 94.2%
Identity: 16%
PDB header:dna-binding protein/dna
Chain: E: PDB Molecule:hth-type transcriptional regulator ttgv;
PDBTitle: crystal structure of ttgv in complex with its dna operator

Phyre2

PDB 1mkm chain A

3D model

Region: 92 - 150
Aligned: 57
Modelled: 59
Confidence: 93.1%
Identity: 18%
PDB header:transcription
Chain: A: PDB Molecule:iclr transcriptional regulator;
PDBTitle: crystal structure of the thermotoga maritima iclr

Phyre2

PDB 1z05 chain A domain 1

3D model

Region: 101 - 144
Aligned: 44
Modelled: 44
Confidence: 92.5%
Identity: 14%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: ROK associated domain

Phyre2

PDB 1qzz chain A domain 1

3D model

Region: 109 - 151
Aligned: 43
Modelled: 43
Confidence: 92.2%
Identity: 21%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: Plant O-methyltransferase, N-terminal domain

Phyre2

PDB 1z6r chain A domain 1

3D model

Region: 98 - 144
Aligned: 47
Modelled: 47
Confidence: 91.5%
Identity: 13%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: ROK associated domain

Phyre2

PDB 3jth chain A

3D model

Region: 86 - 152
Aligned: 64
Modelled: 67
Confidence: 91.1%
Identity: 14%
PDB header:transcription
Chain: A: PDB Molecule:transcription activator hlyu;
PDBTitle: crystal structure of a transcriptional regulator hlyu from2 vibrio vulnificus cmcp6

Phyre2

PDB 2o0y chain B

3D model

Region: 91 - 150
Aligned: 58
Modelled: 60
Confidence: 90.9%
Identity: 14%
PDB header:transcription
Chain: B: PDB Molecule:transcriptional regulator;
PDBTitle: crystal structure of putative transcriptional regulator rha1_ro069532 (iclr-family) from rhodococcus sp.

Phyre2

PDB 1lva chain A domain 3

3D model

Region: 110 - 146
Aligned: 37
Modelled: 37
Confidence: 90.8%
Identity: 22%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: C-terminal fragment of elongation factor SelB

Phyre2

PDB 2d1h chain A domain 1

3D model

Region: 99 - 153
Aligned: 54
Modelled: 0
Confidence: 90.5%
Identity: 30%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: TrmB-like

Phyre2

PDB 1jhf chain A domain 1

3D model

Region: 89 - 142
Aligned: 53
Modelled: 54
Confidence: 90.2%
Identity: 25%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: LexA repressor, N-terminal DNA-binding domain

Phyre2

PDB 1wi9 chain A

3D model

Region: 99 - 156
Aligned: 58
Modelled: 58
Confidence: 90.0%
Identity: 19%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: PCI domain (PINT motif)

Phyre2

PDB 3gwz chain B

3D model

Region: 109 - 151
Aligned: 43
Modelled: 43
Confidence: 89.5%
Identity: 23%
PDB header:transferase
Chain: B: PDB Molecule:mmcr;
PDBTitle: structure of the mitomycin 7-o-methyltransferase mmcr

Phyre2

PDB 2zkz chain C

3D model

Region: 86 - 152
Aligned: 64
Modelled: 67
Confidence: 89.5%
Identity: 9%
PDB header:transcription
Chain: C: PDB Molecule:transcriptional repressor pagr;
PDBTitle: crystal structure of the transcriptional repressor pagr of bacillus2 anthracis

Phyre2

PDB 2quf chain B

3D model

Region: 21 - 147
Aligned: 124
Modelled: 127
Confidence: 88.9%
Identity: 15%
PDB header:transcription
Chain: B: PDB Molecule:transcription factor pf0095;
PDBTitle: crystal structure of transcription factor axxa-pf0095 from pyrococcus2 furiosus

Phyre2

PDB 2zme chain B

3D model

Region: 101 - 151
Aligned: 51
Modelled: 51
Confidence: 88.8%
Identity: 25%
PDB header:protein transport
Chain: B: PDB Molecule:vacuolar protein-sorting-associated protein 36;
PDBTitle: integrated structural and functional model of the human escrt-ii2 complex

Phyre2

PDB 3cuo chain B

3D model

Region: 86 - 158
Aligned: 72
Modelled: 73
Confidence: 88.5%
Identity: 14%
PDB header:transcription regulator
Chain: B: PDB Molecule:uncharacterized hth-type transcriptional regulator ygav;
PDBTitle: crystal structure of the predicted dna-binding transcriptional2 regulator from e. coli

Phyre2

PDB 2r3s chain A

3D model

Region: 85 - 147
Aligned: 62
Modelled: 63
Confidence: 87.9%
Identity: 18%
PDB header:transferase
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a putative o-methyltransferase (npun_r0239) from2 nostoc punctiforme pcc 73102 at 2.15 a resolution

Phyre2

PDB 3bwg chain A domain 1

3D model

Region: 90 - 149
Aligned: 60
Modelled: 60
Confidence: 87.6%
Identity: 17%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: GntR-like transcriptional regulators

Phyre2

PDB 1z6r chain C

3D model

Region: 98 - 153
Aligned: 56
Modelled: 56
Confidence: 87.5%
Identity: 11%
PDB header:transcription
Chain: C: PDB Molecule:mlc protein;
PDBTitle: crystal structure of mlc from escherichia coli

Phyre2

PDB 1tw3 chain A

3D model

Region: 108 - 165
Aligned: 57
Modelled: 57
Confidence: 86.8%
Identity: 23%
PDB header:transferase
Chain: A: PDB Molecule:carminomycin 4-o-methyltransferase;
PDBTitle: crystal structure of carminomycin-4-o-methyltransferase2 (dnrk) in complex with s-adenosyl-l-homocystein (sah) and3 4-methoxy-e-rhodomycin t (m-et)

Phyre2

PDB 2l4a chain A

3D model

Region: 1 - 61
Aligned: 59
Modelled: 59
Confidence: 80.7%
Identity: 20%
PDB header:dna binding protein
Chain: A: PDB Molecule:leucine responsive regulatory protein;
PDBTitle: nmr structure of the dna-binding domain of e.coli lrp

Phyre2
1

d1mkma1
2

c2xroE_
3

c1mkmA_
4

d1z05a1
5

d1qzza1
6

d1z6ra1
7

c3jthA_
8

c2o0yB_
9

d1lvaa3
10

d2d1ha1
11

d1jhfa1
12

d1wi9a_
13

c3gwzB_
14

c2zkzC_
15

c2qufB_
16

c2zmeB_
17

c3cuoB_
18

c2r3sA_
19

d3bwga1
20

c1z6rC_
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c1tw3A_
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c2l4aA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1mkma1



94.5 18 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Transcriptional regulator IclR, N-terminal domain
2c2xroE_



94.2 16 PDB header:dna-binding protein/dna
Chain: E: PDB Molecule:hth-type transcriptional regulator ttgv;
PDBTitle: crystal structure of ttgv in complex with its dna operator
3c1mkmA_



93.1 18 PDB header:transcription
Chain: A: PDB Molecule:iclr transcriptional regulator;
PDBTitle: crystal structure of the thermotoga maritima iclr
4d1z05a1



92.5 14 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:ROK associated domain
5d1qzza1



92.2 21 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Plant O-methyltransferase, N-terminal domain
6d1z6ra1



91.5 13 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:ROK associated domain
7c3jthA_



91.1 14 PDB header:transcription
Chain: A: PDB Molecule:transcription activator hlyu;
PDBTitle: crystal structure of a transcriptional regulator hlyu from2 vibrio vulnificus cmcp6
8c2o0yB_



90.9 14 PDB header:transcription
Chain: B: PDB Molecule:transcriptional regulator;
PDBTitle: crystal structure of putative transcriptional regulator rha1_ro069532 (iclr-family) from rhodococcus sp.
9d1lvaa3



90.8 22 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:C-terminal fragment of elongation factor SelB
10d2d1ha1



90.5 30 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:TrmB-like
11d1jhfa1



90.2 25 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:LexA repressor, N-terminal DNA-binding domain
12d1wi9a_



90.0 19 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:PCI domain (PINT motif)
13c3gwzB_



89.5 23 PDB header:transferase
Chain: B: PDB Molecule:mmcr;
PDBTitle: structure of the mitomycin 7-o-methyltransferase mmcr
14c2zkzC_



89.5 9 PDB header:transcription
Chain: C: PDB Molecule:transcriptional repressor pagr;
PDBTitle: crystal structure of the transcriptional repressor pagr of bacillus2 anthracis
15c2qufB_



88.9 15 PDB header:transcription
Chain: B: PDB Molecule:transcription factor pf0095;
PDBTitle: crystal structure of transcription factor axxa-pf0095 from pyrococcus2 furiosus
16c2zmeB_



88.8 25 PDB header:protein transport
Chain: B: PDB Molecule:vacuolar protein-sorting-associated protein 36;
PDBTitle: integrated structural and functional model of the human escrt-ii2 complex
17c3cuoB_



88.5 14 PDB header:transcription regulator
Chain: B: PDB Molecule:uncharacterized hth-type transcriptional regulator ygav;
PDBTitle: crystal structure of the predicted dna-binding transcriptional2 regulator from e. coli
18c2r3sA_



87.9 18 PDB header:transferase
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a putative o-methyltransferase (npun_r0239) from2 nostoc punctiforme pcc 73102 at 2.15 a resolution
19d3bwga1



87.6 17 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:GntR-like transcriptional regulators
20c1z6rC_



87.5 11 PDB header:transcription
Chain: C: PDB Molecule:mlc protein;
PDBTitle: crystal structure of mlc from escherichia coli
21d1r1ua_



not modelled 87.2 13 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:ArsR-like transcriptional regulators
22c2g7uB_



not modelled 87.2 25 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:transcriptional regulator;
PDBTitle: 2.3 a structure of putative catechol degradative operon regulator from2 rhodococcus sp. rha1
23d1okra_



not modelled 87.1 14 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Penicillinase repressor
24c3mq0A_



not modelled 87.0 21 PDB header:transcription repressor
Chain: A: PDB Molecule:transcriptional repressor of the blcabc operon;
PDBTitle: crystal structure of agobacterium tumefaciens repressor blcr
25c1tw3A_



86.8 23 PDB header:transferase
Chain: A: PDB Molecule:carminomycin 4-o-methyltransferase;
PDBTitle: crystal structure of carminomycin-4-o-methyltransferase2 (dnrk) in complex with s-adenosyl-l-homocystein (sah) and3 4-methoxy-e-rhodomycin t (m-et)
26c2ip2B_



not modelled 86.5 11 PDB header:transferase
Chain: B: PDB Molecule:probable phenazine-specific methyltransferase;
PDBTitle: structure of the pyocyanin biosynthetic protein phzm
27d1sfxa_



not modelled 85.5 18 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:TrmB-like
28c1xduA_



not modelled 85.2 21 PDB header:transferase
Chain: A: PDB Molecule:protein rdmb;
PDBTitle: crystal structure of aclacinomycin-10-hydroxylase (rdmb) in complex2 with sinefungin (sfg)
29c3fmsA_



not modelled 85.0 19 PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator, gntr family;
PDBTitle: crystal structure of tm0439, a gntr transcriptional2 regulator
30d1j5ya1



not modelled 84.9 16 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Biotin repressor-like
31d1biaa1



not modelled 84.7 13 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Biotin repressor-like
32c1x1aA_



not modelled 84.3 14 PDB header:transferase
Chain: A: PDB Molecule:crtf-related protein;
PDBTitle: crystal structure of bchu complexed with s-adenosyl-l-methionine
33c3r4kD_



not modelled 84.0 22 PDB header:dna binding protein
Chain: D: PDB Molecule:transcriptional regulator, iclr family;
PDBTitle: crystal structure of a putative iclr transcriptional regulator2 (tm1040_3717) from silicibacter sp. tm1040 at 2.46 a resolution
34c3lstB_



not modelled 83.8 22 PDB header:transferase
Chain: B: PDB Molecule:calo1 methyltransferase;
PDBTitle: crystal structure of calo1, methyltransferase in calicheamicin2 biosynthesis, sah bound form
35c3f6vA_



not modelled 83.3 21 PDB header:transcription regulator
Chain: A: PDB Molecule:possible transcriptional regulator, arsr family
PDBTitle: crystal structure of possible transcriptional regulator for2 arsenical resistance
36c2zmeA_



not modelled 83.2 18 PDB header:protein transport
Chain: A: PDB Molecule:vacuolar-sorting protein snf8;
PDBTitle: integrated structural and functional model of the human escrt-ii2 complex
37d2hs5a1



not modelled 83.1 11 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:GntR-like transcriptional regulators
38d1stza1



not modelled 83.0 12 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Heat-inducible transcription repressor HrcA, N-terminal domain
39c2pjpA_



not modelled 82.8 10 PDB header:translation/rna
Chain: A: PDB Molecule:selenocysteine-specific elongation factor;
PDBTitle: structure of the mrna-binding domain of elongation factor2 selb from e.coli in complex with secis rna
40c3ihuA_



not modelled 82.6 15 PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator, gntr family;
PDBTitle: crystal structure of dna binding protein (yp_298823.1) from ralstonia2 eutropha jmp134 at 1.92 a resolution
41d2ev0a1



not modelled 82.3 17 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Iron-dependent repressor protein
42c1z05A_



not modelled 82.2 13 PDB header:transcription
Chain: A: PDB Molecule:transcriptional regulator, rok family;
PDBTitle: crystal structure of the rok family transcriptional regulator, homolog2 of e.coli mlc protein.
43c3cuqA_



not modelled 82.2 18 PDB header:protein transport
Chain: A: PDB Molecule:vacuolar-sorting protein snf8;
PDBTitle: integrated structural and functional model of the human escrt-ii2 complex
44c2it0A_



not modelled 81.8 12 PDB header:transcription/dna
Chain: A: PDB Molecule:iron-dependent repressor ider;
PDBTitle: crystal structure of a two-domain ider-dna complex crystal2 form ii
45c3f6oB_



not modelled 80.8 21 PDB header:transcription regulator
Chain: B: PDB Molecule:probable transcriptional regulator, arsr family
PDBTitle: crystal structure of arsr family transcriptional regulator,2 rha00566
46c2l4aA_



80.7 20 PDB header:dna binding protein
Chain: A: PDB Molecule:leucine responsive regulatory protein;
PDBTitle: nmr structure of the dna-binding domain of e.coli lrp
47d1sd4a_



not modelled 79.8 14 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Penicillinase repressor
48c1j5yA_



not modelled 79.3 16 PDB header:transcription
Chain: A: PDB Molecule:transcriptional regulator, biotin repressor family;
PDBTitle: crystal structure of transcriptional regulator (tm1602) from2 thermotoga maritima at 2.3 a resolution
49c2v9vA_



not modelled 79.2 19 PDB header:transcription
Chain: A: PDB Molecule:selenocysteine-specific elongation factor;
PDBTitle: crystal structure of moorella thermoacetica selb(377-511)
50c3r0aB_



not modelled 78.9 16 PDB header:transcription regulator
Chain: B: PDB Molecule:putative transcriptional regulator;
PDBTitle: possible transcriptional regulator from methanosarcina mazei go1 (gi2 21227196)
51c2plyB_



not modelled 78.9 16 PDB header:translation/rna
Chain: B: PDB Molecule:selenocysteine-specific elongation factor;
PDBTitle: structure of the mrna binding fragment of elongation factor2 selb in complex with secis rna.
52d1qbjc_



not modelled 78.5 27 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Z-DNA binding domain
53d1tw3a1



not modelled 78.3 20 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Plant O-methyltransferase, N-terminal domain
54d2gxba1



not modelled 78.1 27 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Z-DNA binding domain
55d1p6ra_



not modelled 77.8 20 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Penicillinase repressor
56c2y75F_



not modelled 77.5 13 PDB header:transcription
Chain: F: PDB Molecule:hth-type transcriptional regulator cymr;
PDBTitle: the structure of cymr (yrzc) the global cysteine regulator2 of b. subtilis
57d1u2wa1



not modelled 77.0 16 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:ArsR-like transcriptional regulators
58c2fe3B_



not modelled 76.1 15 PDB header:dna binding protein
Chain: B: PDB Molecule:peroxide operon regulator;
PDBTitle: the crystal structure of bacillus subtilis perr-zn reveals a novel2 zn(cys)4 structural redox switch
59c2di3A_



not modelled 75.9 10 PDB header:transcription
Chain: A: PDB Molecule:bacterial regulatory proteins, gntr family;
PDBTitle: crystal structure of the transcriptional factor cgl29152 from corynebacterium glutamicum
60c3eqxB_



not modelled 75.6 20 PDB header:dna binding protein
Chain: B: PDB Molecule:fic domain containing transcriptional regulator;
PDBTitle: crystal structure of a fic family protein (so_4266) from shewanella2 oneidensis at 1.6 a resolution
61c2kfsA_



not modelled 74.8 24 PDB header:dna-binding protein
Chain: A: PDB Molecule:conserved hypothetical regulatory protein;
PDBTitle: nmr structure of rv2175c
62d1xd7a_



not modelled 74.6 11 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Transcriptional regulator Rrf2
63c2hs5A_



not modelled 74.6 11 PDB header:transcription regulator
Chain: A: PDB Molecule:putative transcriptional regulator gntr;
PDBTitle: structural genomics, the crystal structure of a putative2 transcriptional regulator gntr from rhodococcus sp. rha1
64d1qgpa_



not modelled 74.3 29 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Z-DNA binding domain
65c3f8mA_



not modelled 74.0 19 PDB header:transcription
Chain: A: PDB Molecule:gntr-family protein transcriptional regulator;
PDBTitle: crystal structure of phnf from mycobacterium smegmatis
66c2ia2D_



not modelled 73.9 10 PDB header:transcription
Chain: D: PDB Molecule:putative transcriptional regulator;
PDBTitle: the crystal structure of a putative transcriptional regulator rha061952 from rhodococcus sp. rha1
67d1hw1a1



not modelled 73.9 17 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:GntR-like transcriptional regulators
68c1f5tA_



not modelled 73.0 13 PDB header:transcription/dna
Chain: A: PDB Molecule:diphtheria toxin repressor;
PDBTitle: diphtheria tox repressor (c102d mutant) complexed with2 nickel and dtxr consensus binding sequence
69c2k4bA_



not modelled 72.8 24 PDB header:dna binding protein
Chain: A: PDB Molecule:transcriptional regulator;
PDBTitle: copr repressor structure
70d3ctaa1



not modelled 72.5 16 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:MarR-like transcriptional regulators
71c1fp2A_



not modelled 72.5 13 PDB header:transferase
Chain: A: PDB Molecule:isoflavone o-methyltransferase;
PDBTitle: crystal structure analysis of isoflavone o-methyltransferase
72d1s3ja_



not modelled 71.8 15 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:MarR-like transcriptional regulators
73c3g3zA_



not modelled 71.7 12 PDB header:transcription
Chain: A: PDB Molecule:transcriptional regulator, marr family;
PDBTitle: the structure of nmb1585, a marr family regulator from neisseria2 meningitidis
74c3k2zA_



not modelled 71.5 29 PDB header:hydrolase
Chain: A: PDB Molecule:lexa repressor;
PDBTitle: crystal structure of a lexa protein from thermotoga maritima
75c2xigA_



not modelled 71.4 12 PDB header:transcription
Chain: A: PDB Molecule:ferric uptake regulation protein;
PDBTitle: the structure of the helicobacter pylori ferric uptake2 regulator fur reveals three functional metal binding sites
76c2x4hA_



not modelled 71.2 8 PDB header:transcription
Chain: A: PDB Molecule:hypothetical protein sso2273;
PDBTitle: crystal structure of the hypothetical protein sso2273 from2 sulfolobus solfataricus
77d1ub9a_



not modelled 71.2 8 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:MarR-like transcriptional regulators
78c3dp7B_



not modelled 70.8 19 PDB header:transferase
Chain: B: PDB Molecule:sam-dependent methyltransferase;
PDBTitle: crystal structure of sam-dependent methyltransferase from bacteroides2 vulgatus atcc 8482
79c3bwgA_



not modelled 70.7 21 PDB header:transcription regulator
Chain: A: PDB Molecule:uncharacterized hth-type transcriptional regulator yydk;
PDBTitle: the crystal structure of possible transcriptional regulator yydk from2 bacillus subtilis subsp. subtilis str. 168
80c3i53A_



not modelled 70.5 23 PDB header:transferase
Chain: A: PDB Molecule:o-methyltransferase;
PDBTitle: crystal structure of an o-methyltransferase (ncsb1) from2 neocarzinostatin biosynthesis in complex with s-adenosyl-l-3 homocysteine (sah)
81c1e2xA_



not modelled 70.2 17 PDB header:transcriptional regulation
Chain: A: PDB Molecule:fatty acid metabolism regulator protein;
PDBTitle: fadr, fatty acid responsive transcription factor from e.2 coli
82c1wsuA_



not modelled 70.0 16 PDB header:translation/rna
Chain: A: PDB Molecule:selenocysteine-specific elongation factor;
PDBTitle: c-terminal domain of elongation factor selb complexed with2 secis rna
83d1ku9a_



not modelled 69.5 13 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:DNA-binding protein Mj223
84c3edpB_



not modelled 68.0 15 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:lin2111 protein;
PDBTitle: the crystal structure of the protein lin2111 (functionally unknown)2 from listeria innocua clip11262
85c3l09B_



not modelled 68.0 10 PDB header:transcription regulator
Chain: B: PDB Molecule:putative transcriptional regulator;
PDBTitle: crystal structure of putative transcriptional regulator2 (jann_22dec04_contig27_revised_gene3569) from jannaschia sp. ccs1 at3 2.81 a resolution
86d1v4ra1



not modelled 66.8 13 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:GntR-like transcriptional regulators
87d2etha1



not modelled 66.6 20 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:MarR-like transcriptional regulators
88c1zgaA_



not modelled 66.4 21 PDB header:plant protein, transferase
Chain: A: PDB Molecule:isoflavanone 4'-o-methyltransferase';
PDBTitle: crystal structure of isoflavanone 4'-o-methyltransferase complexed2 with (+)-6a-hydroxymaackiain
89c2v79B_



not modelled 66.1 24 PDB header:dna-binding protein
Chain: B: PDB Molecule:dna replication protein dnad;
PDBTitle: crystal structure of the n-terminal domain of dnad from2 bacillus subtilis
90d3bz6a2



not modelled 65.4 43 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:PSPTO2686-like
91d1lnwa_



not modelled 65.1 8 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:MarR-like transcriptional regulators
92d1i1ga1



not modelled 64.9 22 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Lrp/AsnC-like transcriptional regulator N-terminal domain
93d2a61a1



not modelled 64.5 25 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:MarR-like transcriptional regulators
94d2fbia1



not modelled 64.4 17 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:MarR-like transcriptional regulators
95d2isya1



not modelled 63.5 19 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Iron-dependent repressor protein
96c3bj6B_



not modelled 61.9 13 PDB header:transcription regulator
Chain: B: PDB Molecule:transcriptional regulator, marr family;
PDBTitle: crystal structure of marr family transcription regulator sp03579
97d1ufma_



not modelled 61.3 22 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:PCI domain (PINT motif)
98c3neuA_



not modelled 60.9 10 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:lin1836 protein;
PDBTitle: the crystal structure of a functionally-unknown protein lin1836 from2 listeria innocua clip11262
99c2oqgA_



not modelled 60.7 25 PDB header:transcription
Chain: A: PDB Molecule:possible transcriptional regulator, arsr family protein;
PDBTitle: arsr-like transcriptional regulator from rhodococcus sp. rha1
100c2vn2B_



not modelled 60.2 18 PDB header:replication
Chain: B: PDB Molecule:chromosome replication initiation protein;
PDBTitle: crystal structure of the n-terminal domain of dnad protein2 from geobacillus kaustophilus hta426
101d2cyya1



not modelled 59.9 10 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Lrp/AsnC-like transcriptional regulator N-terminal domain
102d1g3wa1



not modelled 59.9 18 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Iron-dependent repressor protein
103c3i71B_



not modelled 59.2 28 PDB header:unknown function
Chain: B: PDB Molecule:ethanolamine utilization protein eutk;
PDBTitle: ethanolamine utilization microcompartment shell subunit, eutk c-2 terminal domain
104c2dbbA_



not modelled 59.1 27 PDB header:transcriptional regulator
Chain: A: PDB Molecule:putative hth-type transcriptional regulator ph0061;
PDBTitle: crystal structure of ph0061
105d1l0oc_



not modelled 58.8 27 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Sigma3 and sigma4 domains of RNA polymerase sigma factors
Family:Sigma4 domain
106c1l0oC_



not modelled 58.8 27 PDB header:protein binding
Chain: C: PDB Molecule:sigma factor;
PDBTitle: crystal structure of the bacillus stearothermophilus anti-2 sigma factor spoiiab with the sporulation sigma factor3 sigmaf
107d1mzba_



not modelled 58.8 16 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:FUR-like
108c1u5tB_



not modelled 58.5 18 PDB header:transport protein
Chain: B: PDB Molecule:defective in vacuolar protein sorting; vps36p;
PDBTitle: structure of the escrt-ii endosomal trafficking complex
109c3bpxB_



not modelled 58.4 27 PDB header:transcription regulator
Chain: B: PDB Molecule:transcriptional regulator;
PDBTitle: crystal structure of marr
110c3by6C_



not modelled 58.2 16 PDB header:transcription regulator
Chain: C: PDB Molecule:predicted transcriptional regulator;
PDBTitle: crystal structure of a transcriptional regulator from oenococcus oeni
111c2h09A_



not modelled 58.2 17 PDB header:transcription
Chain: A: PDB Molecule:transcriptional regulator mntr;
PDBTitle: crystal structure of diphtheria toxin repressor like protein2 from e. coli
112c3oopA_



not modelled 57.8 15 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:lin2960 protein;
PDBTitle: the structure of a protein with unknown function from listeria innocua2 clip11262
113d1aoya_



not modelled 57.1 14 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Arginine repressor (ArgR), N-terminal DNA-binding domain
114c3c7jA_



not modelled 57.0 22 PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator, gntr family;
PDBTitle: crystal structure of transcriptional regulator (gntr family member)2 from pseudomonas syringae pv. tomato str. dc3000
115d2cg4a1



not modelled 57.0 14 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Lrp/AsnC-like transcriptional regulator N-terminal domain
116c2jscB_



not modelled 56.3 21 PDB header:transcription
Chain: B: PDB Molecule:transcriptional regulator rv1994c/mt2050;
PDBTitle: nmr structure of the cadmium metal-sensor cmtr from mycobacterium2 tuberculosis
117c1w7pD_



not modelled 56.3 18 PDB header:protein transport
Chain: D: PDB Molecule:vps36p, ylr417w;
PDBTitle: the crystal structure of endosomal complex escrt-ii2 (vps22/vps25/vps36)
118d2bv6a1



not modelled 55.9 13 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:MarR-like transcriptional regulators
119c1u5tA_



not modelled 55.3 19 PDB header:transport protein
Chain: A: PDB Molecule:appears to be functionally related to snf7;
PDBTitle: structure of the escrt-ii endosomal trafficking complex
120c2w48D_



not modelled 54.9 20 PDB header:transcription
Chain: D: PDB Molecule:sorbitol operon regulator;
PDBTitle: crystal structure of the full-length sorbitol operon2 regulator sorc from klebsiella pneumoniae

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0