Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	N	K	A	K	R	L	E	I	L	T	R	L	R	E	N	N	P	H	P	T	T	E	L	N	F	S	S	P	F	E	L	L	I	A	V	L	L	S	A	Q	A	T	D	V	S	V	N	K	A	T	A	K	L	Y	P	V	A	N	T
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	A	A	M	L	E	L	G	V	E	G	V	K	T	Y	I	K	T	I	G	L	Y	N	S	K	A	E	N	I	I	K	T	C	R	I	L	L	E	Q	H	N	G	E	V	P	E	D	R	A	A	L	E	A	L	P	G	V	G	R	K
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	A	N	V	V	L	N	T	A	F	G	W	P	T	I	A	V	D	T	H	I	F	R	V	C	N	R	T	Q	F	A	P	G	K	N	V	E	Q	V	E	E	K	L	L	K	V	V	P	A	E	F	K	V	D	C	H	H	W	L	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.
Sequence		L	H	G	R	Y	T	C	I	A	R	K	P	R	C	G	S	C	I	I	E	D	L	C	E	Y	K	E	K	V	D	I
Secondary structure
SS confidence
Disorder																													?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2abk chain A Region: 1 - 211 Aligned: 211 Modelled: 211 Confidence: 100.0% Identity: 100% Fold: DNA-glycosylase Superfamily: DNA-glycosylase Family: Endonuclease III Phyre2 PDB 1orn chain A Region: 1 - 208 Aligned: 208 Modelled: 208 Confidence: 100.0% Identity: 46% Fold: DNA-glycosylase Superfamily: DNA-glycosylase Family: Endonuclease III Phyre2 PDB 1rrq chain A Region: 3 - 211 Aligned: 204 Modelled: 209 Confidence: 100.0% Identity: 22% PDB header:hydrolase/dna Chain: A: PDB Molecule:muty; PDBTitle: muty adenine glycosylase in complex with dna containing an2 a:oxog pair Phyre2 PDB 1kea chain A Region: 1 - 208 Aligned: 208 Modelled: 208 Confidence: 100.0% Identity: 28% Fold: DNA-glycosylase Superfamily: DNA-glycosylase Family: Mismatch glycosylase Phyre2 PDB 1kg2 chain A Region: 1 - 211 Aligned: 210 Modelled: 211 Confidence: 100.0% Identity: 20% Fold: DNA-glycosylase Superfamily: DNA-glycosylase Family: Mismatch glycosylase Phyre2 PDB 3n5n chain X Region: 1 - 208 Aligned: 207 Modelled: 208 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: X: PDB Molecule:a/g-specific adenine dna glycosylase; PDBTitle: crystal structure analysis of the catalytic domain and interdomain2 connector of human muty homologue Phyre2 PDB 1rrq chain A domain 1 Region: 4 - 208 Aligned: 200 Modelled: 205 Confidence: 100.0% Identity: 22% Fold: DNA-glycosylase Superfamily: DNA-glycosylase Family: Mismatch glycosylase Phyre2 PDB 1pu6 chain A Region: 1 - 190 Aligned: 189 Modelled: 190 Confidence: 100.0% Identity: 16% Fold: DNA-glycosylase Superfamily: DNA-glycosylase Family: 3-Methyladenine DNA glycosylase III (MagIII) Phyre2 PDB 3f10 chain A Region: 8 - 185 Aligned: 170 Modelled: 178 Confidence: 100.0% Identity: 15% PDB header:hydrolase, lyase Chain: A: PDB Molecule:8-oxoguanine-dna-glycosylase; PDBTitle: crystal structure of clostridium acetobutylicum 8-2 oxoguanine dna glycosylase in complex with 8-oxoguanosine Phyre2 PDB 3n0u chain B Region: 3 - 189 Aligned: 172 Modelled: 187 Confidence: 100.0% Identity: 16% PDB header:hydrolase, lyase Chain: B: PDB Molecule:probable n-glycosylase/dna lyase; PDBTitle: crystal structure of tm1821, the 8-oxoguanine dna glycosylase of2 thermotoga maritima Phyre2 PDB 3knt chain C Region: 3 - 189 Aligned: 171 Modelled: 187 Confidence: 100.0% Identity: 18% PDB header:hydrolase, lyase/dna Chain: C: PDB Molecule:n-glycosylase/dna lyase; PDBTitle: crystal structure of methanocaldococcus jannaschii 8-2 oxoguanine glycosylase/lyase in complex with 15mer dna3 containing 8-oxoguanine Phyre2 PDB 3s6i chain A Region: 5 - 178 Aligned: 169 Modelled: 174 Confidence: 100.0% Identity: 17% PDB header:hydrolase/dna Chain: A: PDB Molecule:dna-3-methyladenine glycosylase 1; PDBTitle: schizosaccaromyces pombe 3-methyladenine dna glycosylase (mag1) in2 complex with abasic-dna. Phyre2 PDB 2yg8 chain B Region: 8 - 192 Aligned: 174 Modelled: 172 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:dna-3-methyladenine glycosidase ii, putative; PDBTitle: structure of an unusual 3-methyladenine dna glycosylase ii (2 alka) from deinococcus radiodurans Phyre2 PDB 1ko9 chain A Region: 3 - 182 Aligned: 173 Modelled: 179 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:8-oxoguanine dna glycosylase; PDBTitle: native structure of the human 8-oxoguanine dna glycosylase2 hogg1 Phyre2 PDB 1yqm chain A Region: 3 - 179 Aligned: 170 Modelled: 176 Confidence: 100.0% Identity: 19% PDB header:hydrolase/dna Chain: A: PDB Molecule:n-glycosylase/dna lyase; PDBTitle: catalytically inactive human 8-oxoguanine glycosylase2 crosslinked to 7-deazaguanine containing dna Phyre2 PDB 1mpg chain A domain 1 Region: 18 - 178 Aligned: 150 Modelled: 161 Confidence: 100.0% Identity: 21% Fold: DNA-glycosylase Superfamily: DNA-glycosylase Family: DNA repair glycosylase, 2 C-terminal domains Phyre2 PDB 3fhg chain A Region: 4 - 186 Aligned: 168 Modelled: 183 Confidence: 100.0% Identity: 20% PDB header:dna repair, hydrolase, lyase Chain: A: PDB Molecule:n-glycosylase/dna lyase; PDBTitle: crystal structure of sulfolobus solfataricus 8-oxoguanine dna2 glycosylase (ssogg) Phyre2 PDB 1ngn chain A Region: 26 - 148 Aligned: 116 Modelled: 123 Confidence: 100.0% Identity: 18% Fold: DNA-glycosylase Superfamily: DNA-glycosylase Family: Mismatch glycosylase Phyre2 PDB 2noh chain A domain 1 Region: 28 - 184 Aligned: 153 Modelled: 157 Confidence: 100.0% Identity: 20% Fold: DNA-glycosylase Superfamily: DNA-glycosylase Family: DNA repair glycosylase, 2 C-terminal domains Phyre2 PDB 2jhn chain B Region: 8 - 181 Aligned: 170 Modelled: 174 Confidence: 100.0% Identity: 26% PDB header:hydrolase Chain: B: PDB Molecule:3-methyladenine dna-glycosylase; PDBTitle: 3-methyladenine dna-glycosylase from archaeoglobus fulgidus Phyre2 1 d2abka_ 2 d1orna_ 3 c1rrqA_ 4 d1keaa_ 5 d1kg2a_ 6 c3n5nX_ 7 d1rrqa1 8 d1pu6a_ 9 c3f10A_ 10 c3n0uB_ 11 c3kntC_ 12 c3s6iA_ 13 c2yg8B_ 14 c1ko9A_ 15 c1yqmA_ 16 d1mpga1 17 c3fhgA_ 18 d1ngna_ 19 d2noha1 20 c2jhnB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d2abka_ 100.0 100 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:Endonuclease III 2 d1orna_ 100.0 46 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:Endonuclease III 3 c1rrqA_ 100.0 22 PDB header:hydrolase/dna Chain: A: PDB Molecule:muty; PDBTitle: muty adenine glycosylase in complex with dna containing an2 a:oxog pair 4 d1keaa_ 100.0 28 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:Mismatch glycosylase 5 d1kg2a_ 100.0 20 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:Mismatch glycosylase 6 c3n5nX_ 100.0 21 PDB header:hydrolase Chain: X: PDB Molecule:a/g-specific adenine dna glycosylase; PDBTitle: crystal structure analysis of the catalytic domain and interdomain2 connector of human muty homologue 7 d1rrqa1 100.0 22 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:Mismatch glycosylase 8 d1pu6a_ 100.0 16 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:3-Methyladenine DNA glycosylase III (MagIII) 9 c3f10A_ 100.0 15 PDB header:hydrolase, lyase Chain: A: PDB Molecule:8-oxoguanine-dna-glycosylase; PDBTitle: crystal structure of clostridium acetobutylicum 8-2 oxoguanine dna glycosylase in complex with 8-oxoguanosine 10 c3n0uB_ 100.0 16 PDB header:hydrolase, lyase Chain: B: PDB Molecule:probable n-glycosylase/dna lyase; PDBTitle: crystal structure of tm1821, the 8-oxoguanine dna glycosylase of2 thermotoga maritima 11 c3kntC_ 100.0 18 PDB header:hydrolase, lyase/dna Chain: C: PDB Molecule:n-glycosylase/dna lyase; PDBTitle: crystal structure of methanocaldococcus jannaschii 8-2 oxoguanine glycosylase/lyase in complex with 15mer dna3 containing 8-oxoguanine 12 c3s6iA_ 100.0 17 PDB header:hydrolase/dna Chain: A: PDB Molecule:dna-3-methyladenine glycosylase 1; PDBTitle: schizosaccaromyces pombe 3-methyladenine dna glycosylase (mag1) in2 complex with abasic-dna. 13 c2yg8B_ 100.0 18 PDB header:hydrolase Chain: B: PDB Molecule:dna-3-methyladenine glycosidase ii, putative; PDBTitle: structure of an unusual 3-methyladenine dna glycosylase ii (2 alka) from deinococcus radiodurans 14 c1ko9A_ 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:8-oxoguanine dna glycosylase; PDBTitle: native structure of the human 8-oxoguanine dna glycosylase2 hogg1 15 c1yqmA_ 100.0 19 PDB header:hydrolase/dna Chain: A: PDB Molecule:n-glycosylase/dna lyase; PDBTitle: catalytically inactive human 8-oxoguanine glycosylase2 crosslinked to 7-deazaguanine containing dna 16 d1mpga1 100.0 21 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:DNA repair glycosylase, 2 C-terminal domains 17 c3fhgA_ 100.0 20 PDB header:dna repair, hydrolase, lyase Chain: A: PDB Molecule:n-glycosylase/dna lyase; PDBTitle: crystal structure of sulfolobus solfataricus 8-oxoguanine dna2 glycosylase (ssogg) 18 d1ngna_ 100.0 18 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:Mismatch glycosylase 19 d2noha1 100.0 20 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:DNA repair glycosylase, 2 C-terminal domains 20 c2jhnB_ 100.0 26 PDB header:hydrolase Chain: B: PDB Molecule:3-methyladenine dna-glycosylase; PDBTitle: 3-methyladenine dna-glycosylase from archaeoglobus fulgidus 21 c1mpgB_ not modelled 99.9 22 PDB header:hydrolase Chain: B: PDB Molecule:3-methyladenine dna glycosylase ii; PDBTitle: 3-methyladenine dna glycosylase ii from escherichia coli 22 c2h56C_ not modelled 99.9 14 PDB header:hydrolase Chain: C: PDB Molecule:dna-3-methyladenine glycosidase; PDBTitle: crystal structure of dna-3-methyladenine glycosidase (10174367) from2 bacillus halodurans at 2.55 a resolution 23 c2jg6A_ not modelled 96.1 15 PDB header:hydrolase Chain: A: PDB Molecule:dna-3-methyladenine glycosidase; PDBTitle: crystal structure of a 3-methyladenine dna glycosylase i2 from staphylococcus aureus 24 d1nkua_ not modelled 95.9 22 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:3-Methyladenine DNA glycosylase I (Tag) 25 c2h5xA_ not modelled 95.9 20 PDB header:dna binding protein Chain: A: PDB Molecule:holliday junction atp-dependent dna helicase ruva; PDBTitle: ruva from mycobacterium tuberculosis 26 d1dgsa1 not modelled 95.1 22 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:NAD+-dependent DNA ligase, domain 3 27 d2fmpa1 not modelled 94.6 20 Fold:SAM domain-like Superfamily:DNA polymerase beta, N-terminal domain-like Family:DNA polymerase beta, N-terminal domain-like 28 c2owoA_ not modelled 93.9 23 PDB header:ligase/dna Chain: A: PDB Molecule:dna ligase; PDBTitle: last stop on the road to repair: structure of e.coli dna ligase bound2 to nicked dna-adenylate 29 d2bcqa1 not modelled 93.7 21 Fold:SAM domain-like Superfamily:DNA polymerase beta, N-terminal domain-like Family:DNA polymerase beta, N-terminal domain-like 30 c1vddC_ not modelled 93.3 19 PDB header:recombination Chain: C: PDB Molecule:recombination protein recr; PDBTitle: crystal structure of recombinational repair protein recr 31 d1vdda_ not modelled 92.8 21 Fold:Recombination protein RecR Superfamily:Recombination protein RecR Family:Recombination protein RecR 32 d1nzpa_ not modelled 92.8 19 Fold:SAM domain-like Superfamily:DNA polymerase beta, N-terminal domain-like Family:DNA polymerase beta, N-terminal domain-like 33 c1dgsB_ not modelled 92.7 22 PDB header:ligase Chain: B: PDB Molecule:dna ligase; PDBTitle: crystal structure of nad+-dependent dna ligase from t.2 filiformis 34 d1ixra1 not modelled 92.6 27 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:DNA helicase RuvA subunit, middle domain 35 d1cuka2 not modelled 92.5 35 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:DNA helicase RuvA subunit, middle domain 36 c1ixrA_ not modelled 92.4 27 PDB header:hydrolase Chain: A: PDB Molecule:holliday junction dna helicase ruva; PDBTitle: ruva-ruvb complex 37 d1jmsa1 not modelled 92.4 11 Fold:SAM domain-like Superfamily:DNA polymerase beta, N-terminal domain-like Family:DNA polymerase beta, N-terminal domain-like 38 c8iczA_ not modelled 92.3 20 PDB header:transferase/dna Chain: A: PDB Molecule:protein (dna polymerase beta (e.c.2.7.7.7)); PDBTitle: dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with2 seven base pairs of dna; soaked in the presence of of datp3 (1 millimolar), mncl2 (5 millimolar), and lithium sulfate4 (75 millimolar) 39 d1bvsa2 not modelled 92.1 18 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:DNA helicase RuvA subunit, middle domain 40 d1dk2a_ not modelled 92.0 20 Fold:SAM domain-like Superfamily:DNA polymerase beta, N-terminal domain-like Family:DNA polymerase beta, N-terminal domain-like 41 c2bcuA_ not modelled 91.6 21 PDB header:transferase, lyase/dna Chain: A: PDB Molecule:dna polymerase lambda; PDBTitle: dna polymerase lambda in complex with a dna duplex2 containing an unpaired damp and a t:t mismatch 42 c1d8lA_ not modelled 91.4 45 PDB header:gene regulation Chain: A: PDB Molecule:protein (holliday junction dna helicase ruva); PDBTitle: e. coli holliday junction binding protein ruva nh2 region2 lacking domain iii 43 d2bgwa1 not modelled 90.7 22 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Hef domain-like 44 c1v9pB_ not modelled 90.5 22 PDB header:ligase Chain: B: PDB Molecule:dna ligase; PDBTitle: crystal structure of nad+-dependent dna ligase 45 c1kdhA_ not modelled 90.4 22 PDB header:transferase/dna Chain: A: PDB Molecule:terminal deoxynucleotidyltransferase short PDBTitle: binary complex of murine terminal deoxynucleotidyl2 transferase with a primer single stranded dna 46 d2i1qa1 not modelled 89.7 19 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:DNA repair protein Rad51, N-terminal domain 47 c2ihmA_ not modelled 89.3 17 PDB header:transferase/dna Chain: A: PDB Molecule:dna polymerase mu; PDBTitle: polymerase mu in ternary complex with gapped 11mer dna2 duplex and bound incoming nucleotide 48 c2csdB_ not modelled 88.9 29 PDB header:isomerase Chain: B: PDB Molecule:topoisomerase v; PDBTitle: crystal structure of topoisomerase v (61 kda fragment) 49 d1szpa1 not modelled 88.6 20 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:DNA repair protein Rad51, N-terminal domain 50 c1kftA_ not modelled 87.9 16 PDB header:dna binding protein Chain: A: PDB Molecule:excinuclease abc subunit c; PDBTitle: solution structure of the c-terminal domain of uvrc from e-2 coli 51 d1kfta_ not modelled 87.9 16 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Excinuclease UvrC C-terminal domain 52 c1hjpA_ not modelled 87.8 17 PDB header:dna recombination Chain: A: PDB Molecule:ruva; PDBTitle: holliday junction binding protein ruva from e. coli 53 d1x2ia1 not modelled 87.7 18 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Hef domain-like 54 d1pzna1 not modelled 87.6 22 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:DNA repair protein Rad51, N-terminal domain 55 c2kp7A_ not modelled 87.6 7 PDB header:hydrolase Chain: A: PDB Molecule:crossover junction endonuclease mus81; PDBTitle: solution nmr structure of the mus81 n-terminal hhh.2 northeast structural genomics consortium target mmt1a 56 c2w9mB_ not modelled 87.5 22 PDB header:dna replication Chain: B: PDB Molecule:polymerase x; PDBTitle: structure of family x dna polymerase from deinococcus2 radiodurans 57 c1nomA_ not modelled 86.8 20 PDB header:nucleotidyltransferase Chain: A: PDB Molecule:dna polymerase beta; PDBTitle: dna polymerase beta (pol b) (e.c.2.7.7.7), 31-kd domain; soaked in the2 presence of mncl2 (5 millimolar) 58 d2a1jb1 not modelled 86.8 16 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Hef domain-like 59 d2edua1 not modelled 84.4 23 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:ComEA-like 60 d2duya1 not modelled 82.5 32 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:ComEA-like 61 d3bzka1 not modelled 82.2 14 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Tex HhH-containing domain-like 62 c3c1zA_ not modelled 81.6 18 PDB header:dna binding protein Chain: A: PDB Molecule:dna integrity scanning protein disa; PDBTitle: structure of the ligand-free form of a bacterial dna damage2 sensor protein 63 d1d8ba_ not modelled 80.2 22 Fold:SAM domain-like Superfamily:HRDC-like Family:HRDC domain from helicases 64 d2aq0a1 not modelled 78.3 13 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Hef domain-like 65 c1s5lu_ not modelled 78.1 24 PDB header:photosynthesis Chain: U: PDB Molecule:photosystem ii 12 kda extrinsic protein; PDBTitle: architecture of the photosynthetic oxygen evolving center 66 d1b22a_ not modelled 77.8 10 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:DNA repair protein Rad51, N-terminal domain 67 c1b22A_ not modelled 77.8 10 PDB header:dna binding protein Chain: A: PDB Molecule:dna repair protein rad51; PDBTitle: rad51 (n-terminal domain) 68 d2axtu1 not modelled 76.9 26 Fold:SAM domain-like Superfamily:PsbU/PolX domain-like Family:PsbU-like 69 d2vana1 not modelled 73.9 22 Fold:SAM domain-like Superfamily:PsbU/PolX domain-like Family:DNA polymerase beta-like, second domain 70 d1a77a1 not modelled 73.9 29 Fold:SAM domain-like Superfamily:5' to 3' exonuclease, C-terminal subdomain Family:5' to 3' exonuclease, C-terminal subdomain 71 d2fmpa2 not modelled 73.4 24 Fold:SAM domain-like Superfamily:PsbU/PolX domain-like Family:DNA polymerase beta-like, second domain 72 d1mc8a1 not modelled 73.3 40 Fold:SAM domain-like Superfamily:5' to 3' exonuclease, C-terminal subdomain Family:5' to 3' exonuclease, C-terminal subdomain 73 c3psiA_ not modelled 72.9 16 PDB header:transcription Chain: A: PDB Molecule:transcription elongation factor spt6; PDBTitle: crystal structure of the spt6 core domain from saccharomyces2 cerevisiae, form spt6(239-1451) 74 d1szpb1 not modelled 72.0 20 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:DNA repair protein Rad51, N-terminal domain 75 d1jmsa3 not modelled 71.8 33 Fold:SAM domain-like Superfamily:PsbU/PolX domain-like Family:DNA polymerase beta-like, second domain 76 c3psfA_ not modelled 71.7 18 PDB header:transcription Chain: A: PDB Molecule:transcription elongation factor spt6; PDBTitle: crystal structure of the spt6 core domain from saccharomyces2 cerevisiae, form spt6(236-1259) 77 d2bcqa2 not modelled 71.5 27 Fold:SAM domain-like Superfamily:PsbU/PolX domain-like Family:DNA polymerase beta-like, second domain 78 d1rxwa1 not modelled 69.7 36 Fold:SAM domain-like Superfamily:5' to 3' exonuclease, C-terminal subdomain Family:5' to 3' exonuclease, C-terminal subdomain 79 d1xo1a1 not modelled 67.2 23 Fold:SAM domain-like Superfamily:5' to 3' exonuclease, C-terminal subdomain Family:5' to 3' exonuclease, C-terminal subdomain 80 d1b43a1 not modelled 66.9 29 Fold:SAM domain-like Superfamily:5' to 3' exonuclease, C-terminal subdomain Family:5' to 3' exonuclease, C-terminal subdomain 81 d1lb2b_ not modelled 66.6 21 Fold:SAM domain-like Superfamily:C-terminal domain of RNA polymerase alpha subunit Family:C-terminal domain of RNA polymerase alpha subunit 82 d2csba3 not modelled 64.9 58 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Topoisomerase V repeat domain 83 d2i5ha1 not modelled 64.1 26 Fold:AF1531-like Superfamily:AF1531-like Family:AF1531-like 84 c2i5hA_ not modelled 64.1 26 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein af1531; PDBTitle: crystal structure of af1531 from archaeoglobus fulgidus,2 pfam duf655 85 d1ul1x1 not modelled 63.2 29 Fold:SAM domain-like Superfamily:5' to 3' exonuclease, C-terminal subdomain Family:5' to 3' exonuclease, C-terminal subdomain 86 d1cooa_ not modelled 62.7 21 Fold:SAM domain-like Superfamily:C-terminal domain of RNA polymerase alpha subunit Family:C-terminal domain of RNA polymerase alpha subunit 87 d1z3eb1 not modelled 62.6 21 Fold:SAM domain-like Superfamily:C-terminal domain of RNA polymerase alpha subunit Family:C-terminal domain of RNA polymerase alpha subunit 88 d1i94m_ not modelled 61.1 35 Fold:S13-like H2TH domain Superfamily:S13-like H2TH domain Family:Ribosomal protein S13 89 d1doqa_ not modelled 60.4 21 Fold:SAM domain-like Superfamily:C-terminal domain of RNA polymerase alpha subunit Family:C-terminal domain of RNA polymerase alpha subunit 90 c2nrzB_ not modelled 58.1 15 PDB header:hydrolase Chain: B: PDB Molecule:uvrabc system protein c; PDBTitle: crystal structure of the c-terminal half of uvrc bound to2 its catalytic divalent cation 91 c2oceA_ not modelled 57.8 27 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein pa5201; PDBTitle: crystal structure of tex family protein pa5201 from2 pseudomonas aeruginosa 92 c3iz6M_ not modelled 57.7 45 PDB header:ribosome Chain: M: PDB Molecule:40s ribosomal protein s18 (s13p); PDBTitle: localization of the small subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome 93 c2xznM_ not modelled 56.4 35 PDB header:ribosome Chain: M: PDB Molecule:rps18e; PDBTitle: crystal structure of the eukaryotic 40s ribosomal2 subunit in complex with initiation factor 1. this file3 contains the 40s subunit and initiation factor for4 molecule 2 94 c2zkqm_ not modelled 55.5 53 PDB header:ribosomal protein/rna Chain: M: PDB Molecule: PDBTitle: structure of a mammalian ribosomal 40s subunit within an2 80s complex obtained by docking homology models of the rna3 and proteins into an 8.7 a cryo-em map 95 d2gy9m1 not modelled 55.5 35 Fold:S13-like H2TH domain Superfamily:S13-like H2TH domain Family:Ribosomal protein S13 96 c1ut8B_ not modelled 55.2 20 PDB header:hydrolase Chain: B: PDB Molecule:exodeoxyribonuclease; PDBTitle: divalent metal ions (zinc) bound to t5 5'-exonuclease 97 c2ziuA_ not modelled 52.4 24 PDB header:hydrolase Chain: A: PDB Molecule:mus81 protein; PDBTitle: crystal structure of the mus81-eme1 complex 98 d2uubm1 not modelled 52.4 35 Fold:S13-like H2TH domain Superfamily:S13-like H2TH domain Family:Ribosomal protein S13 99 d1cmwa1 not modelled 51.4 56 Fold:SAM domain-like Superfamily:5' to 3' exonuclease, C-terminal subdomain Family:5' to 3' exonuclease, C-terminal subdomain 100 c2izoA_ not modelled 50.6 21 PDB header:hydrolase Chain: A: PDB Molecule:flap structure-specific endonuclease; PDBTitle: structure of an archaeal pcna1-pcna2-fen1 complex 101 d1wuda1 not modelled 50.4 19 Fold:SAM domain-like Superfamily:HRDC-like Family:HRDC domain from helicases 102 d2p6ra2 not modelled 49.9 24 Fold:Sec63 N-terminal domain-like Superfamily:Sec63 N-terminal domain-like Family:Achaeal helicase C-terminal domain 103 c1a77A_ not modelled 47.2 40 PDB header:5'-3' exo/endo nuclease Chain: A: PDB Molecule:flap endonuclease-1 protein; PDBTitle: flap endonuclease-1 from methanococcus jannaschii 104 d1gm5a2 not modelled 46.8 20 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:RecG "wedge" domain 105 c3q8lA_ not modelled 45.0 29 PDB header:hydrolase/dna Chain: A: PDB Molecule:flap endonuclease 1; PDBTitle: crystal structure of human flap endonuclease fen1 (wt) in complex with2 substrate 5'-flap dna, sm3+, and k+ 106 c1b43A_ not modelled 42.9 29 PDB header:transferase Chain: A: PDB Molecule:protein (fen-1); PDBTitle: fen-1 from p. furiosus 107 c1rxvA_ not modelled 42.1 36 PDB header:hydrolase/dna Chain: A: PDB Molecule:flap structure-specific endonuclease; PDBTitle: crystal structure of a. fulgidus fen-1 bound to dna 108 c3mr2A_ not modelled 40.2 8 PDB header:transferase/dna Chain: A: PDB Molecule:dna polymerase eta; PDBTitle: human dna polymerase eta in complex with normal dna and incoming2 nucleotide (nrm) 109 c1gm5A_ not modelled 39.9 14 PDB header:helicase Chain: A: PDB Molecule:recg; PDBTitle: structure of recg bound to three-way dna junction 110 c2bhnD_ not modelled 39.5 11 PDB header:hydrolase Chain: D: PDB Molecule:xpf endonuclease; PDBTitle: xpf from aeropyrum pernix 111 c1cmwA_ not modelled 38.5 45 PDB header:transferase Chain: A: PDB Molecule:protein (dna polymerase i); PDBTitle: crystal structure of taq dna-polymerase shows a new2 orientation for the structure-specific nuclease domain 112 c3oryA_ not modelled 37.0 29 PDB header:hydrolase Chain: A: PDB Molecule:flap endonuclease 1; PDBTitle: crystal structure of flap endonuclease 1 from hyperthermophilic2 archaeon desulfurococcus amylolyticus 113 c2rhfA_ not modelled 36.9 33 PDB header:hydrolase Chain: A: PDB Molecule:dna helicase recq; PDBTitle: d. radiodurans recq hrdc domain 3 114 d1jx4a2 not modelled 36.7 13 Fold:DNA/RNA polymerases Superfamily:DNA/RNA polymerases Family:Lesion bypass DNA polymerase (Y-family), catalytic domain 115 d1t57a_ not modelled 36.0 23 Fold:Pyruvate kinase C-terminal domain-like Superfamily:PK C-terminal domain-like Family:MTH1675-like 116 c1ul1Y_ not modelled 34.4 29 PDB header:hydrolase/dna binding protein Chain: Y: PDB Molecule:flap endonuclease-1; PDBTitle: crystal structure of the human fen1-pcna complex 117 c2rrdA_ not modelled 33.6 19 PDB header:dna binding protein Chain: A: PDB Molecule:hrdc domain from bloom syndrome protein; PDBTitle: structure of hrdc domain from human bloom syndrome protein, blm 118 c3qeaZ_ not modelled 32.2 40 PDB header:hydrolase/dna Chain: Z: PDB Molecule:exonuclease 1; PDBTitle: crystal structure of human exonuclease 1 exo1 (wt) in complex with dna2 (complex ii) 119 c1k1qA_ not modelled 31.6 13 PDB header:transcription Chain: A: PDB Molecule:dbh protein; PDBTitle: crystal structure of a dinb family error prone dna2 polymerase from sulfolobus solfataricus 120 d2e1fa1 not modelled 31.1 19 Fold:SAM domain-like Superfamily:HRDC-like Family:HRDC domain from helicases

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0