Email l.a.kelley@imperial.ac.uk Description P22939 Date Thu Jan 5 11:39:12 GMT 2012 Unique Job ID 0159194e84c36ebf

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1rqja_ 100.0 100 Fold:Terpenoid synthases Superfamily:Terpenoid synthases Family:Isoprenyl diphosphate synthases 2 c2forB_ 100.0 99 PDB header:transferase Chain: B: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of the shigella flexneri farnesyl pyrophosphate2 synthase complex with an isopentenyl pyrophosphate 3 c3ts7B_ 100.0 49 PDB header:transferase Chain: B: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of farnesyl diphosphate synthase (target efi-501951)2 from methylococcus capsulatus 4 c1wy0A_ 100.0 35 PDB header:transferase Chain: A: PDB Molecule:geranylgeranyl pyrophosphate synthetase; PDBTitle: crystal structure of geranylgeranyl pyrophosphate synthetase from2 pyrococcus horikoshii ot3 5 c3mzvB_ 100.0 33 PDB header:transferase Chain: B: PDB Molecule:decaprenyl diphosphate synthase; PDBTitle: crystal structure of a decaprenyl diphosphate synthase from2 rhodobacter capsulatus 6 c3aqbD_ 100.0 29 PDB header:transferase Chain: D: PDB Molecule:component b of hexaprenyl diphosphate synthase; PDBTitle: m. luteus b-p 26 heterodimeric hexaprenyl diphosphate synthase in2 complex with magnesium 7 c3lsnA_ 100.0 47 PDB header:transferase Chain: A: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of putative geranyltranstransferase from pseudomonas2 fluorescens pf-5 complexed with magnesium 8 c3m9uD_ 100.0 41 PDB header:transferase Chain: D: PDB Molecule:farnesyl-diphosphate synthase; PDBTitle: crystal structure of geranylgeranyl pyrophosphate synthase2 from lactobacillus brevis atcc 367 9 c3lomA_ 100.0 35 PDB header:transferase Chain: A: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of geranyltransferase from legionella2 pneumophila 10 c3oyrB_ 100.0 33 PDB header:transferase Chain: B: PDB Molecule:trans-isoprenyl diphosphate synthase; PDBTitle: crystal structure of polyprenyl synthase from caulobacter crescentus2 cb15 complexed with calcium and isoprenyl diphosphate 11 c3nf2A_ 100.0 33 PDB header:transferase Chain: A: PDB Molecule:putative polyprenyl synthetase; PDBTitle: crystal structure of polyprenyl synthetase from streptomyces2 coelicolor a3(2) 12 c2h8oA_ 100.0 43 PDB header:transferase Chain: A: PDB Molecule:geranyltranstransferase; PDBTitle: the 1.6a crystal structure of the geranyltransferase from2 agrobacterium tumefaciens 13 d1rtra_ 100.0 39 Fold:Terpenoid synthases Superfamily:Terpenoid synthases Family:Isoprenyl diphosphate synthases 14 c2j1pB_ 100.0 43 PDB header:transferase Chain: B: PDB Molecule:geranylgeranyl pyrophosphate synthetase; PDBTitle: geranylgeranyl diphosphate synthase from sinapis alba in2 complex with ggpp 15 d1fpsa_ 100.0 24 Fold:Terpenoid synthases Superfamily:Terpenoid synthases Family:Isoprenyl diphosphate synthases 16 c3llwA_ 100.0 34 PDB header:transferase Chain: A: PDB Molecule:geranyltranstransferase (ispa); PDBTitle: crystal structure of geranyltransferase from helicobacter2 pylori 26695 17 c3ucaB_ 100.0 38 PDB header:transferase Chain: B: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of isoprenoid synthase (target efi-501974) from2 clostridium perfringens 18 c1wmwA_ 100.0 26 PDB header:transferase Chain: A: PDB Molecule:geranylgeranyl diphosphate synthetase; PDBTitle: crystal structure of geranulgeranyl diphosphate synthase from thermus2 thermophilus 19 c3cp6A_ 100.0 24 PDB header:transferase Chain: A: PDB Molecule:farnesyl pyrophosphate synthetase; PDBTitle: crystal structure of human farnesyl diphosphate synthase (t201a2 mutant) complexed with mg and biphosphonate inhibitor 20 c2ogdB_ 100.0 22 PDB header:transferase Chain: B: PDB Molecule:farnesyl pyrophosphate synthase; PDBTitle: t. brucei farnesyl diphosphate synthase complexed with bisphosphonate2 bph-527 21 c1yhlA_ not modelled 100.0 22 PDB header:transferase Chain: A: PDB Molecule:farnesyl pyrophosphate synthase; PDBTitle: structure of the complex of trypanosoma cruzi farnesyl diphosphate2 synthase with risedronate, dmapp and mg+2 22 c3m0gB_ not modelled 100.0 46 PDB header:transferase Chain: B: PDB Molecule:farnesyl diphosphate synthase; PDBTitle: crystal structure of putative farnesyl diphosphate synthase from2 rhodobacter capsulatus 23 c2f94F_ not modelled 100.0 24 PDB header:transferase Chain: F: PDB Molecule:farnesyl diphosphate synthase; PDBTitle: crystal structure of human fpps in complex with ibandronate 24 c3p8lB_ not modelled 100.0 38 PDB header:transferase Chain: B: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of polyprenyl synthase from enterococcus faecalis2 v583 25 d1v4ea_ not modelled 100.0 28 Fold:Terpenoid synthases Superfamily:Terpenoid synthases Family:Isoprenyl diphosphate synthases 26 c3ez3A_ not modelled 100.0 21 PDB header:lyase Chain: A: PDB Molecule:farnesyl pyrophosphate synthase, putative; PDBTitle: crystal structure of plasmodium vivax geranylgeranylpyrophosphate2 synthase pvx_092040 with zoledronate and ipp bound 27 c3npkB_ not modelled 100.0 36 PDB header:transferase Chain: B: PDB Molecule:geranyltranstransferase; PDBTitle: the crystal structure of geranyltranstransferase from campylobacter2 jejuni 28 c2e8xB_ not modelled 100.0 22 PDB header:transferase Chain: B: PDB Molecule:geranylgeranyl pyrophosphate synthetase; PDBTitle: s. cerevisiae geranylgeranyl pyrophosphate synthase in2 complex with magnesium and gpp 29 d2q80a1 not modelled 100.0 25 Fold:Terpenoid synthases Superfamily:Terpenoid synthases Family:Isoprenyl diphosphate synthases 30 c2o1oB_ not modelled 100.0 21 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative farnesyl pyrophosphate synthase; PDBTitle: cryptosporidium parvum putative polyprenyl pyrophosphate2 synthase (cgd4_2550) in complex with risedronate. 31 c3n3dB_ not modelled 100.0 30 PDB header:transferase Chain: B: PDB Molecule:geranylgeranyl pyrophosphate synthase; PDBTitle: crystal structure of geranylgeranyl pyrophosphate synthase from2 lactobacillus brevis atcc 367 32 c3ipiA_ not modelled 100.0 23 PDB header:transferase Chain: A: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of a geranyltranstransferase from the2 methanosarcina mazei 33 c3p8rA_ not modelled 100.0 58 PDB header:transferase Chain: A: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of polyprenyl synthase from vibrio cholerae 34 c3aq0G_ not modelled 100.0 27 PDB header:transferase Chain: G: PDB Molecule:geranyl diphosphate synthase; PDBTitle: ligand-bound form of arabidopsis medium/long-chain length prenyl2 pyrophosphate synthase (surface polar residue mutant) 35 c2azjB_ not modelled 100.0 21 PDB header:transferase Chain: B: PDB Molecule:geranylgeranyl pyrophosphate synthetase; PDBTitle: crystal structure for the mutant d81c of sulfolobus2 solfataricus hexaprenyl pyrophosphate synthase 36 c3lk5A_ not modelled 100.0 30 PDB header:transferase Chain: A: PDB Molecule:geranylgeranyl pyrophosphate synthase; PDBTitle: crystal structure of putative geranylgeranyl pyrophosphate synthase2 from corynebacterium glutamicum 37 c2j1oA_ not modelled 100.0 43 PDB header:transferase Chain: A: PDB Molecule:geranylgeranyl pyrophosphate synthetase; PDBTitle: geranylgeranyl diphosphate synthase from sinapis alba 38 c3lmdA_ not modelled 100.0 31 PDB header:transferase Chain: A: PDB Molecule:geranylgeranyl pyrophosphate synthase; PDBTitle: crystal structure of geranylgeranyl pyrophosphate synthase2 from corynebacterium glutamicum atcc 13032 39 c3rmgB_ not modelled 100.0 27 PDB header:transferase Chain: B: PDB Molecule:octaprenyl-diphosphate synthase; PDBTitle: crystal structure of geranylgeranyl pyrophosphate synthase from2 bacteroides thetaiotaomicron 40 c3kraB_ not modelled 100.0 22 PDB header:transferase Chain: B: PDB Molecule:geranyl diphosphate synthase small subunit; PDBTitle: mint heterotetrameric geranyl pyrophosphate synthase in2 complex with magnesium 41 c3tc1A_ not modelled 100.0 28 PDB header:transferase Chain: A: PDB Molecule:octaprenyl pyrophosphate synthase; PDBTitle: crystal structure of octaprenyl pyrophosphate synthase from2 helicobacter pylori 42 c3qkcB_ not modelled 100.0 18 PDB header:transferase Chain: B: PDB Molecule:geranyl diphosphate synthase small subunit; PDBTitle: crystal structure of geranyl diphosphate synthase small subunit from2 antirrhinum majus 43 c3oyrA_ not modelled 100.0 28 PDB header:transferase Chain: A: PDB Molecule:trans-isoprenyl diphosphate synthase; PDBTitle: crystal structure of polyprenyl synthase from caulobacter crescentus2 cb15 complexed with calcium and isoprenyl diphosphate 44 c2ftzA_ not modelled 100.0 30 PDB header:transferase Chain: A: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of geranyltranstransferase (ec 2.5.1.10) (tm0161)2 from thermotoga maritima at 1.90 a resolution 45 d1ezfa_ not modelled 96.3 27 Fold:Terpenoid synthases Superfamily:Terpenoid synthases Family:Squalene synthase 46 c2zcpA_ not modelled 95.7 14 PDB header:transferase Chain: A: PDB Molecule:dehydrosqualene synthase; PDBTitle: crystal structure of the c(30) carotenoid dehydrosqualene2 synthase from staphylococcus aureus complexed with3 farnesyl thiopyrophosphate 47 d1n1ba2 not modelled 75.3 13 Fold:Terpenoid synthases Superfamily:Terpenoid synthases Family:Terpenoid cyclase C-terminal domain 48 c1hx9A_ not modelled 72.7 16 PDB header:lyase Chain: A: PDB Molecule:5-epi-aristolochene synthase; PDBTitle: crystal structure of teas w273s form 1 49 c3n0fA_ not modelled 70.3 12 PDB header:lyase Chain: A: PDB Molecule:isoprene synthase; PDBTitle: crystal structure of isoprene synthase from grey poplar leaves2 (populus x canescens) 50 c3saeA_ not modelled 67.5 15 PDB header:lyase Chain: A: PDB Molecule:alpha-bisabolene synthase; PDBTitle: structure of a three-domain sesquiterpene synthase: a prospective2 target for advanced biofuels production 51 c1n20A_ not modelled 66.9 12 PDB header:isomerase Chain: A: PDB Molecule:(+)-bornyl diphosphate synthase; PDBTitle: (+)-bornyl diphosphate synthase: complex with mg and 3-aza-2 2,3-dihydrogeranyl diphosphate 52 d5easa2 not modelled 59.7 16 Fold:Terpenoid synthases Superfamily:Terpenoid synthases Family:Terpenoid cyclase C-terminal domain 53 c2ongA_ not modelled 58.9 10 PDB header:lyase Chain: A: PDB Molecule:4s-limonene synthase; PDBTitle: crystal structure of of limonene synthase with 2-2 fluorogeranyl diphosphate (fgpp). 54 c3g4dB_ not modelled 56.3 9 PDB header:lyase Chain: B: PDB Molecule:(+)-delta-cadinene synthase isozyme xc1; PDBTitle: crystal structure of (+)-delta-cadinene synthase from gossypium2 arboreum and evolutionary divergence of metal binding motifs for3 catalysis 55 d2o3la1 not modelled 55.7 16 Fold:Left-handed superhelix Superfamily:BH3980-like Family:BH3980-like 56 c3p5rB_ not modelled 55.6 13 PDB header:lyase Chain: B: PDB Molecule:taxadiene synthase; PDBTitle: crystal structure of taxadiene synthase from pacific yew (taxus2 brevifolia) in complex with mg2+ and 2-fluorogeranylgeranyl3 diphosphate 57 c3s9vD_ not modelled 51.7 9 PDB header:lyase, isomerase Chain: D: PDB Molecule:abietadiene synthase, chloroplastic; PDBTitle: abietadiene synthase from abies grandis 58 d2hh6a1 not modelled 43.7 29 Fold:Left-handed superhelix Superfamily:BH3980-like Family:BH3980-like 59 c2j5cB_ not modelled 39.1 14 PDB header:lyase Chain: B: PDB Molecule:1,8-cineole synthase; PDBTitle: rational conversion of substrate and product specificity2 in a monoterpene synthase. structural insights into the3 molecular basis of rapid evolution. 60 d2htja1 not modelled 34.0 36 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:FaeA-like 61 c3byvA_ not modelled 28.8 24 PDB header:transferase Chain: A: PDB Molecule:rhoptry kinase; PDBTitle: crystal structure of toxoplasma gondii specific rhoptry2 antigen kinase domain 62 c3q60A_ not modelled 24.3 10 PDB header:transferase Chain: A: PDB Molecule:rop5b; PDBTitle: crystal structure of virulent allele rop5b pseudokinase domain bound2 to atp 63 d2o4ta1 not modelled 23.8 23 Fold:Left-handed superhelix Superfamily:BH3980-like Family:BH3980-like 64 c3e7eA_ not modelled 18.3 24 PDB header:transferase Chain: A: PDB Molecule:mitotic checkpoint serine/threonine-protein kinase bub1; PDBTitle: structure and substrate recruitment of the human spindle checkpoint2 kinase bub 65 c3lg5A_ not modelled 18.1 11 PDB header:lyase Chain: A: PDB Molecule:epi-isozizaene synthase; PDBTitle: f198a epi-isozizaene synthase: complex with mg, inorganic2 pyrophosphate and benzyl triethyl ammonium cation 66 c2jiiA_ not modelled 16.2 19 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase vrk3 molecule: vaccinia PDBTitle: structure of vaccinia related kinase 3 67 c2v62A_ not modelled 16.0 24 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase vrk2; PDBTitle: structure of vaccinia-related kinase 2 68 c3dzoA_ not modelled 12.8 24 PDB header:transferase Chain: A: PDB Molecule:rhoptry kinase domain; PDBTitle: crystal structure of a rhoptry kinase from toxoplasma gondii 69 c1tqmA_ not modelled 10.3 29 PDB header:ribosome Chain: A: PDB Molecule:conserved hypothetical protein; PDBTitle: crystal structure of a. fulgidus rio2 serine protein kinase bound to2 amppnp 70 c2j0kB_ not modelled 9.8 14 PDB header:transferase Chain: B: PDB Molecule:focal adhesion kinase 1; PDBTitle: crystal structure of a fragment of focal adhesion kinase2 containing the ferm and kinase domains. 71 c2wtkC_ not modelled 9.4 19 PDB header:transferase/metal-binding protein Chain: C: PDB Molecule:serine/threonine-protein kinase 11; PDBTitle: structure of the heterotrimeric lkb1-stradalpha-mo25alpha2 complex 72 c3qa8A_ not modelled 8.4 33 PDB header:immune system, signaling protein Chain: A: PDB Molecule:mgc80376 protein; PDBTitle: crystal structure of inhibitor of kappa b kinase beta 73 c2ctoA_ not modelled 8.3 30 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:novel protein; PDBTitle: solution structure of the hmg box like domain from human2 hypothetical protein flj14904 74 c3c4yA_ not modelled 8.2 24 PDB header:transferase Chain: A: PDB Molecule:rhodopsin kinase; PDBTitle: crystal structure of apo form of g protein coupled receptor kinase 12 at 7.51a 75 c3a1yF_ not modelled 8.2 36 PDB header:ribosomal protein Chain: F: PDB Molecule:50s ribosomal protein p1 (l12p); PDBTitle: the structure of protein complex 76 c2pziA_ not modelled 8.0 29 PDB header:transferase Chain: A: PDB Molecule:probable serine/threonine-protein kinase pkng; PDBTitle: crystal structure of protein kinase pkng from mycobacterium2 tuberculosis in complex with tetrahydrobenzothiophene ax20017 77 c3fbvL_ not modelled 7.8 38 PDB header:transferase, hydrolase Chain: L: PDB Molecule:serine/threonine-protein kinase/endoribonuclease ire1; PDBTitle: crystal structure of the oligomer formed by the kinase-ribonuclease2 domain of ire1 78 d1ps1a_ not modelled 7.4 15 Fold:Terpenoid synthases Superfamily:Terpenoid synthases Family:Aristolochene/pentalenene synthase 79 c2oa6B_ not modelled 7.3 14 PDB header:lyase Chain: B: PDB Molecule:aristolochene synthase; PDBTitle: aristolochene synthase from aspergillus terreus complexed with2 pyrophosphate 80 c3op5B_ not modelled 7.3 24 PDB header:transferase Chain: B: PDB Molecule:serine/threonine-protein kinase vrk1; PDBTitle: human vaccinia-related kinase 1 81 c2acxB_ not modelled 7.1 19 PDB header:transferase Chain: B: PDB Molecule:g protein-coupled receptor kinase 6; PDBTitle: crystal structure of g protein coupled receptor kinase 6 bound to2 amppnp 82 c1ym7C_ not modelled 6.9 19 PDB header:transferase Chain: C: PDB Molecule:beta-adrenergic receptor kinase 1; PDBTitle: g protein-coupled receptor kinase 2 (grk2) 83 c2ozoA_ not modelled 6.7 14 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70 84 c1u57A_ not modelled 6.6 13 PDB header:viral protein Chain: A: PDB Molecule:gag polyprotein; PDBTitle: nmr structure of the (345-392)gag sequence from hiv-1 85 c3cvjB_ not modelled 6.5 15 PDB header:isomerase Chain: B: PDB Molecule:putative phosphoheptose isomerase; PDBTitle: crystal structure of a putative phosphoheptose isomerase (bh3325) from2 bacillus halodurans c-125 at 2.00 a resolution 86 c2vwiC_ not modelled 6.5 29 PDB header:transferase Chain: C: PDB Molecule:serine/threonine-protein kinase osr1; PDBTitle: structure of the osr1 kinase, a hypertension drug target 87 c3i3aC_ not modelled 6.2 9 PDB header:transferase Chain: C: PDB Molecule:acyl-[acyl-carrier-protein]--udp-n- PDBTitle: structural basis for the sugar nucleotide and acyl chain2 selectivity of leptospira interrogans lpxa 88 d1vjja1 not modelled 6.1 67 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:Transglutaminase N-terminal domain 89 d1g0da1 not modelled 6.1 67 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:Transglutaminase N-terminal domain 90 c3t98A_ not modelled 5.9 40 PDB header:protein transport Chain: A: PDB Molecule:nuclear pore complex protein nup54; PDBTitle: molecular architecture of the transport channel of the nuclear pore2 complex: nup54/nup58 91 c3pjaK_ not modelled 5.9 2 PDB header:hydrolase Chain: K: PDB Molecule:translin-associated protein x; PDBTitle: crystal structure of human c3po complex 92 d2q3za1 not modelled 5.9 67 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:Transglutaminase N-terminal domain 93 c2c47D_ not modelled 5.8 29 PDB header:transferase Chain: D: PDB Molecule:casein kinase 1 gamma 2 isoform; PDBTitle: structure of casein kinase 1 gamma 2 94 d1sq8a_ not modelled 5.7 16 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:Phage repressors 95 c1hm4A_ not modelled 5.5 11 PDB header:lyase Chain: A: PDB Molecule:pentalenene synthase; PDBTitle: n219l pentalenene synthase 96 c2r17C_ not modelled 5.5 20 PDB header:protein transport Chain: C: PDB Molecule:vacuolar protein sorting-associated protein 35; PDBTitle: functional architecture of the retromer cargo-recognition complex 97 d1riqa1 not modelled 5.4 20 Fold:Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Superfamily:Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Family:Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 98 c2vuwA_ not modelled 5.2 29 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase haspin; PDBTitle: structure of human haspin kinase domain