1 c1ycsB_
100.0
100
PDB header: complex (anti-oncogene/ankyrin repeats)Chain: B: PDB Molecule: 53bp2;PDBTitle: p53-53bp2 complex
2 c2vgeA_
100.0
52
PDB header: transcriptionChain: A: PDB Molecule: rela-associated inhibitor;PDBTitle: crystal structure of the c-terminal region of human iaspp
3 d1ycsb1
99.8
100
Fold: beta-hairpin-alpha-hairpin repeatSuperfamily: Ankyrin repeatFamily: Ankyrin repeat4 d1n11a_
99.8
33
Fold: beta-hairpin-alpha-hairpin repeatSuperfamily: Ankyrin repeatFamily: Ankyrin repeat5 c1n11A_
99.8
33
PDB header: structural proteinChain: A: PDB Molecule: ankyrin;PDBTitle: d34 region of human ankyrin-r and linker
6 c3jueA_
99.7
23
PDB header: protein transport/endocytosisChain: A: PDB Molecule: arfgap with coiled-coil, ank repeat and ph domain-PDBTitle: crystal structure of arfgap and ank repeat domain of acap1
7 c2b0oF_
99.7
26
PDB header: metal binding proteinChain: F: PDB Molecule: uplc1;PDBTitle: crystal structure of uplc1 gap domain
8 c3lvrE_
99.7
22
PDB header: protein transportChain: E: PDB Molecule: arf-gap with sh3 domain, ank repeat and ph domain-PDBTitle: the crystal structure of asap3 in complex with arf6 in transition2 state soaked with calcium
9 d1s70b_
99.7
45
Fold: beta-hairpin-alpha-hairpin repeatSuperfamily: Ankyrin repeatFamily: Ankyrin repeat10 c3ui2A_
99.7
20
PDB header: transport proteinChain: A: PDB Molecule: signal recognition particle 43 kda protein, chloroplastic;PDBTitle: crystal structure of the cpsrp54 tail bound to cpsrp43
11 c1dcqA_
99.6
21
PDB header: metal binding proteinChain: A: PDB Molecule: pyk2-associated protein beta;PDBTitle: crystal structure of the arf-gap domain and ankyrin repeats2 of papbeta.
12 c3keaB_
99.6
19
PDB header: viral proteinChain: B: PDB Molecule: k1l;PDBTitle: structure function studies of vaccinia virus host-range protein k12 reveal a novel ankyrin repeat interaction surface for k1s function
13 c3utmA_
99.6
24
PDB header: transferase/signaling proteinChain: A: PDB Molecule: tankyrase-1;PDBTitle: crystal structure of a mouse tankyrase-axin complex
14 d2ajaa1
99.6
16
Fold: alpha-alpha superhelixSuperfamily: Pseudo ankyrin repeat-likeFamily: Pseudo ankyrin repeat15 d1dcqa1
99.6
25
Fold: beta-hairpin-alpha-hairpin repeatSuperfamily: Ankyrin repeatFamily: Ankyrin repeat16 c2fo1E_
99.6
21
PDB header: gene regulation/signalling protein/dnaChain: E: PDB Molecule: lin-12 protein;PDBTitle: crystal structure of the csl-notch-mastermind ternary2 complex bound to dna
17 c2ajaA_
99.6
15
PDB header: protein bindingChain: A: PDB Molecule: ankyrin repeat family protein;PDBTitle: x-ray structure of an ankyrin repeat family protein q5zsv02 from legionella pneumophila. northeast structural genomics3 consortium target lgr21.
18 d2fo1e1
99.6
20
Fold: beta-hairpin-alpha-hairpin repeatSuperfamily: Ankyrin repeatFamily: Ankyrin repeat19 c3ljnA_
99.5
24
PDB header: unknown functionChain: A: PDB Molecule: hypothetical protein;PDBTitle: ankyrin repeat protein from leishmania major
20 c2rfaA_
99.5
36
PDB header: membrane proteinChain: A: PDB Molecule: transient receptor potential cation channel subfamily vPDBTitle: crystal structure of the mouse trpv6 ankyrin repeat domain
21 c2zgdA_
not modelled
99.5
30
PDB header: de novo proteinChain: A: PDB Molecule: 3 repeat synthetic ankyrin;PDBTitle: asn-hydroxylation stabilises the ankyrin repeat domain fold
22 d1ycsb2
not modelled
99.5
100
Fold: SH3-like barrelSuperfamily: SH3-domainFamily: SH3-domain23 c1sw6A_
not modelled
99.5
18
PDB header: transcription regulationChain: A: PDB Molecule: regulatory protein swi6;PDBTitle: s. cerevisiae swi6 ankyrin-repeat fragment
24 d1sw6a_
not modelled
99.5
18
Fold: beta-hairpin-alpha-hairpin repeatSuperfamily: Ankyrin repeatFamily: Ankyrin repeat25 d1uoha_
not modelled
99.5
47
Fold: beta-hairpin-alpha-hairpin repeatSuperfamily: Ankyrin repeatFamily: Ankyrin repeat26 c2xenA_
not modelled
99.5
29
PDB header: de novo proteinChain: A: PDB Molecule: ni1c mut4;PDBTitle: structural determinants for improved thermal stability of2 designed ankyrin repeat proteins with a redesigned c-3 capping module.
27 c3hraA_
not modelled
99.5
34
PDB header: structural proteinChain: A: PDB Molecule: ankyrin repeat family protein;PDBTitle: crystal structure of ef0377 an ankyrin repeat protein
28 c3deoA_
not modelled
99.5
25
PDB header: protein transport, membrane proteinChain: A: PDB Molecule: signal recognition particle 43 kda protein;PDBTitle: structural basis for specific substrate recognition by the2 chloroplast signal recognition particle protein cpsrp43
29 d1wdya_
not modelled
99.4
24
Fold: beta-hairpin-alpha-hairpin repeatSuperfamily: Ankyrin repeatFamily: Ankyrin repeat30 c3ehrB_
not modelled
99.4
24
PDB header: signaling proteinChain: B: PDB Molecule: osteoclast-stimulating factor 1;PDBTitle: crystal structure of human osteoclast stimulating factor
31 c2f8xK_
not modelled
99.4
18
PDB header: transcription/dnaChain: K: PDB Molecule: neurogenic locus notch homolog protein 1;PDBTitle: crystal structure of activated notch, csl and maml on hes-12 promoter dna sequence
32 c2kbxA_
not modelled
99.4
23
PDB header: cell adhesionChain: A: PDB Molecule: integrin-linked protein kinase;PDBTitle: solution structure of ilk-pinch complex
33 c1n0qB_
not modelled
99.4
41
PDB header: structural proteinChain: B: PDB Molecule: 3 ankyrin repeats;PDBTitle: 3ank: a designed ankyrin repeat protein with three identical consensus2 repeats
34 c2xaiD_
not modelled
99.4
27
PDB header: transcriptionChain: D: PDB Molecule: ankyrin repeat and socs box protein 9;PDBTitle: crystal structure of ankyrin repeat and socs box-containing2 protein 9 (asb9) in complex with elonginb and elonginc
35 d1iknd_
not modelled
99.4
21
Fold: beta-hairpin-alpha-hairpin repeatSuperfamily: Ankyrin repeatFamily: Ankyrin repeat36 c3eu9B_
not modelled
99.4
25
PDB header: protein binding, methyl-lysine-binding pChain: B: PDB Molecule: huntingtin-interacting protein 14;PDBTitle: the ankyrin repeat domain of huntingtin interacting protein 14
37 d1ot8a_
not modelled
99.4
18
Fold: beta-hairpin-alpha-hairpin repeatSuperfamily: Ankyrin repeatFamily: Ankyrin repeat38 c3b7bB_
not modelled
99.3
36
PDB header: transferaseChain: B: PDB Molecule: euchromatic histone-lysine n-methyltransferase 1;PDBTitle: euhmt1 (glp) ankyrin repeat domain (structure 1)
39 c3d9hA_
not modelled
99.3
27
PDB header: structural protein, protein bindingChain: A: PDB Molecule: cdna flj77766, highly similar to homo sapiensPDBTitle: crystal structure of the splice variant of human asb92 (hasb9-2), an ankyrin repeat protein
40 c3t8kB_
not modelled
99.3
13
PDB header: structural genomics, unknown functionChain: B: PDB Molecule: uncharacterized protein;PDBTitle: the crystal structure of a functionally unknown protein lebu_0176 from2 leptotrichia buccalis c-1013-b
41 c3jxiA_
not modelled
99.3
22
PDB header: membrane proteinChain: A: PDB Molecule: vanilloid receptor-related osmotically activated channelPDBTitle: crystal structure of the chicken trpv4 ankyrin repeat domain
42 d1ixva_
not modelled
99.3
35
Fold: beta-hairpin-alpha-hairpin repeatSuperfamily: Ankyrin repeatFamily: Ankyrin repeat43 d1blxb_
not modelled
99.3
30
Fold: beta-hairpin-alpha-hairpin repeatSuperfamily: Ankyrin repeatFamily: Ankyrin repeat44 c3v30A_
not modelled
99.3
28
PDB header: protein bindingChain: A: PDB Molecule: dna-binding protein rfxank;PDBTitle: crystal structure of the peptide bound complex of the ankyrin repeat2 domains of human rfxank
45 c2f37B_
not modelled
99.3
24
PDB header: membrane proteinChain: B: PDB Molecule: transient receptor potential cation channelPDBTitle: crystal structure of the ankyrin repeat domain of human2 trpv2
46 c1oy3D_
not modelled
99.3
24
PDB header: dna binding proteinChain: D: PDB Molecule: transcription factor inhibitor i-kappa-b-beta;PDBTitle: crystal structure of an ikbbeta/nf-kb p65 homodimer complex
47 d1oy3d_
not modelled
99.3
24
Fold: beta-hairpin-alpha-hairpin repeatSuperfamily: Ankyrin repeatFamily: Ankyrin repeat48 c2rfmB_
not modelled
99.3
33
PDB header: protein bindingChain: B: PDB Molecule: putative ankyrin repeat protein tv1425;PDBTitle: structure of a thermophilic ankyrin repeat protein
49 d1k1aa_
not modelled
99.3
22
Fold: beta-hairpin-alpha-hairpin repeatSuperfamily: Ankyrin repeatFamily: Ankyrin repeat50 d1bi7b_
not modelled
99.3
24
Fold: beta-hairpin-alpha-hairpin repeatSuperfamily: Ankyrin repeatFamily: Ankyrin repeat51 c1n0rA_
not modelled
99.3
66
PDB header: structural proteinChain: A: PDB Molecule: 4 ankyrin repeats;PDBTitle: 4ank: a designed ankyrin repeat protein with four identical2 consensus repeats
52 c2v5qC_
not modelled
99.3
41
PDB header: transferaseChain: C: PDB Molecule: design ankyrin repeat protein;PDBTitle: crystal structure of wild-type plk-1 kinase domain in2 complex with a selective darpin
53 d2a5ea_
not modelled
99.2
21
Fold: beta-hairpin-alpha-hairpin repeatSuperfamily: Ankyrin repeatFamily: Ankyrin repeat54 c2jabC_
not modelled
99.2
30
PDB header: de novo proteinChain: C: PDB Molecule: h10-2-g3;PDBTitle: a designed ankyrin repeat protein evolved to picomolar2 affinity to her2
55 d1ihba_
not modelled
99.2
32
Fold: beta-hairpin-alpha-hairpin repeatSuperfamily: Ankyrin repeatFamily: Ankyrin repeat56 c2l6bA_
not modelled
99.2
32
PDB header: de novo proteinChain: A: PDB Molecule: nr1c;PDBTitle: nrc consensus ankyrin repeat protein solution structure
57 d1awcb_
not modelled
99.2
24
Fold: beta-hairpin-alpha-hairpin repeatSuperfamily: Ankyrin repeatFamily: Ankyrin repeat58 c1ympB_
not modelled
99.2
22
PDB header: transcriptionChain: B: PDB Molecule: notch 1 protein;PDBTitle: the crystal structure of a partial mouse notch-1 ankyrin2 domain: repeats 4 through 7 preserve an ankyrin fold
59 c3twtD_
not modelled
99.2
28
PDB header: signaling protein/peptideChain: D: PDB Molecule: tankyrase-2;PDBTitle: crystal structure of arc4 from human tankyrase 2 in complex with2 peptide from human mcl1 (chimeric peptide)
60 c3nmzD_
not modelled
99.2
36
PDB header: cell adhesion/cell cycleChain: D: PDB Molecule: rho guanine nucleotide exchange factor 4;PDBTitle: crytal structure of apc complexed with asef
61 d1myoa_
not modelled
99.2
28
Fold: beta-hairpin-alpha-hairpin repeatSuperfamily: Ankyrin repeatFamily: Ankyrin repeat62 c1ympA_
not modelled
99.2
22
PDB header: transcriptionChain: A: PDB Molecule: notch 1 protein;PDBTitle: the crystal structure of a partial mouse notch-1 ankyrin2 domain: repeats 4 through 7 preserve an ankyrin fold
63 d1bd8a_
not modelled
99.1
32
Fold: beta-hairpin-alpha-hairpin repeatSuperfamily: Ankyrin repeatFamily: Ankyrin repeat64 c2nyjA_
not modelled
99.1
17
PDB header: transport proteinChain: A: PDB Molecule: transient receptor potential cation channelPDBTitle: crystal structure of the ankyrin repeat domain of trpv1
65 c1wyxA_
not modelled
99.1
29
PDB header: cell adhesionChain: A: PDB Molecule: crk-associated substrate;PDBTitle: the crystal structure of the p130cas sh3 domain at 1.1 a2 resolution
66 c2kymA_
not modelled
99.1
27
PDB header: signaling proteinChain: A: PDB Molecule: bud emergence protein 1;PDBTitle: solution structure of the bem1p sh3-ci domain from l.elongisporus in2 complex with ste20p peptide
67 d1ug1a_
not modelled
99.1
19
Fold: SH3-like barrelSuperfamily: SH3-domainFamily: SH3-domain68 c2dnuA_
not modelled
99.1
29
PDB header: structural genomics, structural proteinChain: A: PDB Molecule: sh3 multiple domains 1;PDBTitle: solution structure of rsgi ruh-061, a sh3 domain from human
69 c1griA_
not modelled
99.1
34
PDB header: signal transduction adaptorChain: A: PDB Molecule: growth factor bound protein 2;PDBTitle: grb2
70 c2yupA_
not modelled
99.1
21
PDB header: cell adhesionChain: A: PDB Molecule: vinexin;PDBTitle: solution structure of the second sh3 domain of human vinexin
71 c2jxbA_
not modelled
99.1
35
PDB header: signaling protein complexChain: A: PDB Molecule: t-cell surface glycoprotein cd3 epsilon chain,PDBTitle: structure of cd3epsilon-nck2 first sh3 domain complex
72 c2egeA_
not modelled
99.1
32
PDB header: structural genomics, unknown functionChain: A: PDB Molecule: uncharacterized protein kiaa1666;PDBTitle: solution structure of the third sh3 domain from human2 kiaa1666 protein
73 d1ng2a2
not modelled
99.1
33
Fold: SH3-like barrelSuperfamily: SH3-domainFamily: SH3-domain74 c2ysqA_
not modelled
99.1
28
PDB header: signaling proteinChain: A: PDB Molecule: rho guanine nucleotide exchange factor 9;PDBTitle: solution structure of the sh3 domain from rho guanine2 nucleotide exchange factor 9
75 d1i1ja_
not modelled
99.1
20
Fold: SH3-like barrelSuperfamily: SH3-domainFamily: SH3-domain76 c1u3oA_
not modelled
99.1
28
PDB header: signaling proteinChain: A: PDB Molecule: huntingtin-associated protein-interactingPDBTitle: solution structure of rat kalirin n-terminal sh3 domain
77 c2i0nA_
not modelled
99.1
32
PDB header: structural proteinChain: A: PDB Molecule: class vii unconventional myosin;PDBTitle: structure of dictyostelium discoideum myosin vii sh3 domain2 with adjacent proline rich region
78 d1k9aa1
not modelled
99.1
22
Fold: SH3-like barrelSuperfamily: SH3-domainFamily: SH3-domain79 c2d8hA_
not modelled
99.1
28
PDB header: unknown functionChain: A: PDB Molecule: sh3yl1 protein;PDBTitle: solution structure of the sh3 domain of hypothetical2 protein sh3yl1
80 c2yunA_
not modelled
99.1
31
PDB header: protein transportChain: A: PDB Molecule: nostrin;PDBTitle: solution structure of the sh3 domain of human nostrin
81 c2creA_
not modelled
99.0
31
PDB header: structural genomics, unknown functionChain: A: PDB Molecule: hef-like protein;PDBTitle: solution structure of rsgi ruh-036, an sh3 domain from2 human cdna
82 c2k2mA_
not modelled
99.0
31
PDB header: signaling proteinChain: A: PDB Molecule: eps8-like protein 1;PDBTitle: structural basis of pxxdy motif recognition in sh3 binding
83 c1w70A_
not modelled
99.0
21
PDB header: sh3 domainChain: A: PDB Molecule: neutrophil cytosol factor 4;PDBTitle: sh3 domain of p40phox complexed with c-terminal polyproline2 region of p47phox
84 c2azsA_
not modelled
99.0
30
PDB header: signaling proteinChain: A: PDB Molecule: sh2-sh3 adapter protein drk;PDBTitle: nmr structure of the n-terminal sh3 domain of drk2 (calculated without noe restraints)
85 c2ct4A_
not modelled
99.0
26
PDB header: signaling proteinChain: A: PDB Molecule: cdc42-interacting protein 4;PDBTitle: solution strutcure of the sh3 domain of the cdc42-2 interacting protein 4
86 c1x2pA_
not modelled
99.0
24
PDB header: transferaseChain: A: PDB Molecule: protein arginine n-methyltransferase 2;PDBTitle: solution structure of the sh3 domain of the protein2 arginine n-methyltransferase 2
87 c2a28D_
not modelled
99.0
31
PDB header: signaling proteinChain: D: PDB Molecule: bzz1 protein;PDBTitle: atomic-resolution crystal structure of the second sh32 domain of yeast bzz1 determined from a pseudomerohedrally3 twinned crystal
88 c2ekhA_
not modelled
99.0
23
PDB header: signaling proteinChain: A: PDB Molecule: sh3 and px domain-containing protein 2a;PDBTitle: solution structures of the sh3 domain of human kiaa0418
89 d1uffa_
not modelled
99.0
24
Fold: SH3-like barrelSuperfamily: SH3-domainFamily: SH3-domain90 c1wx6A_
not modelled
99.0
28
PDB header: structural genomics, unknown functionChain: A: PDB Molecule: cytoplasmic protein nck2;PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck2
91 c1x2qA_
not modelled
99.0
25
PDB header: signaling proteinChain: A: PDB Molecule: signal transducing adapter molecule 2;PDBTitle: solution structure of the sh3 domain of the signal2 transducing adaptor molecule 2
92 c2eywA_
not modelled
99.0
34
PDB header: signaling proteinChain: A: PDB Molecule: v-crk sarcoma virus ct10 oncogene homologPDBTitle: n-terminal sh3 domain of ct10-regulated kinase
93 d1ov3a2
not modelled
99.0
34
Fold: SH3-like barrelSuperfamily: SH3-domainFamily: SH3-domain94 c2dl5A_
not modelled
99.0
29
PDB header: structural genomics, unknown functionChain: A: PDB Molecule: kiaa0769 protein;PDBTitle: solution structure of the first sh3 domain of human2 kiaa0769 protein
95 d1gbra_
not modelled
99.0
35
Fold: SH3-like barrelSuperfamily: SH3-domainFamily: SH3-domain96 c2xmfA_
not modelled
99.0
33
PDB header: motor proteinChain: A: PDB Molecule: myosin 1e sh3;PDBTitle: myosin 1e sh3
97 c3c5rB_
not modelled
99.0
28
PDB header: protein bindingChain: B: PDB Molecule: brca1-associated ring domain protein 1;PDBTitle: crystal structure of the bard1 ankyrin repeat domain and its2 functional consequences
98 c2csqA_
not modelled
99.0
31
PDB header: endocytosis/exocytosisChain: A: PDB Molecule: rim binding protein 2;PDBTitle: solution structure of the second sh3 domain of human rim-2 binding protein 2
99 c1x6gA_
not modelled
99.0
20
PDB header: signaling proteinChain: A: PDB Molecule: megakaryocyte-associated tyrosine-protein kinase;PDBTitle: solution structures of the sh3 domain of human2 megakaryocyte-associated tyrosine-protein kinase.
100 c2dl7A_
not modelled
99.0
33
PDB header: structural genomics, unknown functionChain: A: PDB Molecule: kiaa0769 protein;PDBTitle: solution structure of the second sh3 domain of human2 kiaa0769 protein
101 c1mv3A_
not modelled
99.0
30
PDB header: endocytosis/exocytosisChain: A: PDB Molecule: myc box dependent interacting protein 1;PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc
102 d1udla_
not modelled
99.0
26
Fold: SH3-like barrelSuperfamily: SH3-domainFamily: SH3-domain103 c2dl8A_
not modelled
99.0
27
PDB header: signaling proteinChain: A: PDB Molecule: slit-robo rho gtpase-activating protein 2;PDBTitle: solution structure of the sh3 domain of human slit-robo rho2 gtpase-activating protein 2
104 c2yuoA_
not modelled
99.0
33
PDB header: signaling proteinChain: A: PDB Molecule: run and tbc1 domain containing 3;PDBTitle: solution structure of the sh3 domain of mouse run and tbc12 domain containing 3
105 c2l0aA_
not modelled
99.0
30
PDB header: signaling proteinChain: A: PDB Molecule: signal transducing adapter molecule 1;PDBTitle: solution nmr structure of signal transducing adapter molecule 1 stam-12 from homo sapiens, northeast structural genomics consortium target3 hr4479e
106 d1uhca_
not modelled
99.0
28
Fold: SH3-like barrelSuperfamily: SH3-domainFamily: SH3-domain107 d1uuea_
not modelled
99.0
31
Fold: SH3-like barrelSuperfamily: SH3-domainFamily: SH3-domain108 c2cubA_
not modelled
99.0
22
PDB header: signaling proteinChain: A: PDB Molecule: cytoplasmic protein nck1;PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck1
109 c2cudA_
not modelled
99.0
24
PDB header: signaling proteinChain: A: PDB Molecule: src-like-adapter;PDBTitle: solution structure of the sh3 domain of the human src-like2 adopter protein (slap)
110 d1e6ga_
not modelled
99.0
31
Fold: SH3-like barrelSuperfamily: SH3-domainFamily: SH3-domain111 c2dmoA_
not modelled
99.0
26
PDB header: signaling proteinChain: A: PDB Molecule: neutrophil cytosol factor 2;PDBTitle: refined solution structure of the 1st sh3 domain from human2 neutrophil cytosol factor 2 (ncf-2)
112 d1k4us_
not modelled
99.0
31
Fold: SH3-like barrelSuperfamily: SH3-domainFamily: SH3-domain113 d1uj0a_
not modelled
99.0
32
Fold: SH3-like barrelSuperfamily: SH3-domainFamily: SH3-domain114 c2rqrA_
not modelled
99.0
17
PDB header: protein bindingChain: A: PDB Molecule: engulfment and cell motility protein 1, linker, dedicatorPDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex
115 d1j3ta_
not modelled
99.0
23
Fold: SH3-like barrelSuperfamily: SH3-domainFamily: SH3-domain116 c2yt6A_
not modelled
99.0
33
PDB header: cell cycleChain: A: PDB Molecule: adult male urinary bladder cdna, riken full-PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1
117 c1x43A_
not modelled
99.0
24
PDB header: endocytosis/exocytosisChain: A: PDB Molecule: sh3 domain grb2-like protein b1;PDBTitle: solution structure of the sh3 domain of endophilin b12 (sh3g1b1)
118 c1zlmA_
not modelled
99.0
35
PDB header: signaling proteinChain: A: PDB Molecule: osteoclast stimulating factor 1;PDBTitle: crystal structure of the sh3 domain of human osteoclast2 stimulating factor
119 d1pwta_
not modelled
99.0
35
Fold: SH3-like barrelSuperfamily: SH3-domainFamily: SH3-domain120 c3nhnA_
not modelled
99.0
39
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase hck;PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region
