Phyre 2 Results for Q6TXD4

Email	l.a.kelley@imperial.ac.uk
Description	Q6TXD4
Date	Tue Jul 30 13:06:16 BST 2013
Unique Job ID	3e4e7cfa0db1a39a
Sequence	MEPGSMVRAI ... Download FASTA

Summary

Top model

Image coloured by rainbow N → C terminus

Model dimensions (Å):

X:57.596 Y:48.289 Z:53.523

Model (left) based on template c2dx1A_

Top template information

PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crystal structure of rhogef protein asef

Confidence and coverage

Confidence:

100.0%

Coverage:

17%

264 residues ( 17% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.

Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.

944 residues ( 60%) could be modelled at >90% confidence using multiple-templates.

You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.

Warning: 61% of your sequence is predicted disordered. Disordered regions cannot be meaningfully predicted.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M E P G S M V R A I F D F C P S V S E E L P L F V G D V I E V L A V V D E F W L L G K K E D V T G Q F P S S F V E I V T

Secondary structure

SS confidence

Disorder ? ? ? ? ?
? ? ? ?
?
? ? ? ?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence I P S L K E G E R L F V C I C E F V S R E L N S L S L H R G D L V I L D D S A P T A G W L Q G R S C W G A W G F F P S S

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ?
?
? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence C V Q E L C L S S R S R R W H A Q S A L L Q A P E Y S L G Q A R A L M G L S A Q L D E E L D F R E G D L I T I I G V P E

Secondary structure

SS confidence

Disorder
?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240

Sequence P G W F E G E L E G R R G I F P E G F V E L L G P L R T V D E S V N S R S G D D S A V N G E V D V P P E E A E S G G D E

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280 . . . . . . . . . 290 . . . . . . . . . 300

Sequence D D Q Q S G T Y G I A L Y R F Q A L E T N E L D F E V G D R I Q I L G T L E D G W L E G C L K G K T G V F P H R F V K L

Secondary structure

SS confidence

Disorder ? ? ? ? ?
?
? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350 . . . . . . . . . 360

Sequence C P S N R T E E T T A Q P Q E S S F P K D S E S S V G K S G D S V V E E A R Q E P W E C E E E R P D Y D L P G Q A S V P

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence Q D H V A P E W T G D T I S G Q D K D A S G S S P D V D L E R P L A K D L S T P D P S E E V N G V S S Q P Q V P I H P K

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ?

Disorder confidence

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480

Sequence V Q K S Q H Y L T A G G S H Q T S D P F S E L V P L E A R T R D Y S S L P P R R T Y A Q G W S F Q K P A S H L Q R A S S

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 490 . . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540

Sequence L T A S R L D R P S H F C H P A M A S Y A Q K H Q T S T E N T A S L H D P P E R P E R R P G L Q D R G P A T D I T T A S

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 550 . . . . . . . . . 560 . . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600

Sequence Q G D S L D L D S K L T Q Q L I E F E K S L S G P S T E P E T I V R R F S I M D F Y S E K D I V R G S S N S L P S Q A F

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ?
?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630 . . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660

Sequence P E R R K T L R P P P P R P R T P T P I S S H L L V D Q S P K P V P T L V V R P S R P A P L P P P A Q Q R M N T A S P K

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700 . . . . . . . . . 710 . . . . . . . . . 720

Sequence P T S C A H P G W E A P E K E D S E H M E K S P A Q T F P C P S M L A R I R D V E Q D L D T C T R A Q E E L N L L L E E

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770 . . . . . . . . . 780

Sequence K Q D D P S R A E T L E T L R S Y E S T I Q S L T L E L Q Q L R D M T L L S S Q S S S L A A P F G S V S T E N P E Q R M

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence L E K R A K V V A E L L Q T E R D Y I R D L E M C I E R V M V P L Q Q A Q V P N V D F E G L F G N M Q T V I K V S K Q L

Secondary structure

SS confidence

Disorder
? ?
?

Disorder confidence

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900

Sequence L A A L E I S D A V G M S S C D C L V P G P V F L D H R D E L E G T Y R V Y C Q N H D E A I S L L E M Y E K D E K T Q K

Secondary structure

SS confidence

Disorder
? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 910 . . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960

Sequence H L Q D Y L A D L K G C T N Y I N L G S F L I K P V Q R I M R Y P L L L M E L L N S T P E S H P D K V P L T N A V L A V

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ?
?
?

Disorder confidence

. . . . . . . . . 970 . . . . . . . . . 980 . . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020

Sequence K E I N V N I N E Y K R R K D L V L K Y R K G D E D S L M E K I S K L N I H S I I K K S S R V S S H L K H L T G F A P Q

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ?
? ?
?

Disorder confidence

. . . . . . . . . 1030 . . . . . . . . . 1040 . . . . . . . . . 1050 . . . . . . . . . 1060 . . . . . . . . . 1070 . . . . . . . . . 1080

Sequence L K D E V F E E T E K N F R M Q E R L I K S F I R D L S L Y L Q H I R E S A C V K V V A A M S I W D L C M E R G H H D L

Secondary structure

SS confidence

Disorder ? ? ? ? ?
?
? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 1090 . . . . . . . . . 1100 . . . . . . . . . 1110 . . . . . . . . . 1120 . . . . . . . . . 1130 . . . . . . . . . 1140

Sequence E Q F E K V H R Y I S D Q L F T R F K E R T E R L V I N P L N Q L L N M F T G P Y K L V Q K R F D K L L D F Y N C T E R

Secondary structure

SS confidence

Disorder
?

Disorder confidence

. . . . . . . . . 1150 . . . . . . . . . 1160 . . . . . . . . . 1170 . . . . . . . . . 1180 . . . . . . . . . 1190 . . . . . . . . . 1200

Sequence A E K L K D K K T L E E L Q S A R N N Y E A L N S Q L L D E L P K F Q Q Y A Q S L F T N C I H G Y A E A H C D F V Q Q A

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 1210 . . . . . . . . . 1220 . . . . . . . . . 1230 . . . . . . . . . 1240 . . . . . . . . . 1250 . . . . . . . . . 1260

Sequence L E Q L Q P L L S L L K A T D R E G N L I A I F L E E H S R V L Q Q L Q V F T F F P E S L P A P R K P F E R K T T D R Q

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 1270 . . . . . . . . . 1280 . . . . . . . . . 1290 . . . . . . . . . 1300 . . . . . . . . . 1310 . . . . . . . . . 1320

Sequence S S R K T L L G M P S Y M L Q S E E L R S S L L A R Y P P E K L F H V Q R N F N A A Q D L D V S L L E G D L V G V I K K

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
?
?
? ?
? ? ? ? ? ? ? ? ? ?
?
? ?
? ?

Disorder confidence

. . . . . . . . . 1330 . . . . . . . . . 1340 . . . . . . . . . 1350 . . . . . . . . . 1360 . . . . . . . . . 1370 . . . . . . . . . 1380

Sequence K D P M G S Q N R W L V D N G V T K G F V Y S S F L K P Y N P R C S H S D A S V A S H S S T E S E H S G S S P G C H R Q

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ?
?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 1390 . . . . . . . . . 1400 . . . . . . . . . 1410 . . . . . . . . . 1420 . . . . . . . . . 1430 . . . . . . . . . 1440

Sequence N S H S A L T F N S N N M T V S F T S G L A L T Q P Q D A S P L K D C A H E T L A V S W N T G H P E T G P S T C S S D P

Secondary structure

SS confidence

Disorder
? ?
?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 1450 . . . . . . . . . 1460 . . . . . . . . . 1470 . . . . . . . . . 1480 . . . . . . . . . 1490 . . . . . . . . . 1500

Sequence G F S C Q R R L G N P A D G A R D I S Q P A S T L R G C Q R S S P H S E V V G Y S V P G R N D Q G S D S I K G S A R V C

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 1510 . . . . . . . . . 1520 . . . . . . . . . 1530 . . . . . . . . . 1540 . . . . . . . . . 1550 . . . . . . . . . 1560

Sequence Q A P E D R D R G V G S S E T E G N Q V Y F A I Y T F K A R N P N E L S V L A N Q R L R I H E F K D V T G N T E W W L A

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ?
?
? ? ?
? ?

Disorder confidence

. . . . . . . . . 1570 . . . . . . . . . 1580

Sequence E V N G R K G Y V P S N Y I R K T E Y T

Secondary structure

SS confidence

Disorder
? ? ? ? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered ( 61%)

Alpha helix ( 32%)

Beta strand ( 8%)

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 2dx1 chain A

Region: 244 - 982
Aligned: 264
Modelled: 269
Confidence: 100.0%
Identity: 41%
PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crystal structure of rhogef protein asef

Phyre2

PDB 3jv3 chain A

Region: 245 - 979
Aligned: 275
Modelled: 278
Confidence: 100.0%
Identity: 38%
PDB header:protein binding
Chain: A: PDB Molecule:intersectin-1;
PDBTitle: structure of sh3e-dh unit of murine intersectin-1l

Phyre2

PDB 3ky9 chain B

Region: 780 - 986
Aligned: 198
Modelled: 207
Confidence: 100.0%
Identity: 24%
PDB header:apoptosis
Chain: B: PDB Molecule:proto-oncogene vav;
PDBTitle: autoinhibited vav1

Phyre2

PDB 4gou chain A

Region: 774 - 985
Aligned: 202
Modelled: 212
Confidence: 100.0%
Identity: 15%
PDB header:signaling protein
Chain: A: PDB Molecule:ehrgs-rhogef;
PDBTitle: crystal structure of an rgs-rhogef from entamoeba histolytica

Phyre2

PDB 3ksy chain A

Region: 783 - 982
Aligned: 197
Modelled: 200
Confidence: 100.0%
Identity: 20%
PDB header:signaling protein
Chain: A: PDB Molecule:son of sevenless homolog 1;
PDBTitle: crystal structure of the histone domain, dh-ph unit, and2 catalytic unit of the ras activator son of sevenless (sos)

Phyre2

PDB 2vrw chain B

Region: 780 - 986
Aligned: 198
Modelled: 207
Confidence: 100.0%
Identity: 25%
PDB header:signaling protein
Chain: B: PDB Molecule:proto-oncogene vav;
PDBTitle: critical structural role for the ph and c1 domains of the2 vav1 exchange factor

Phyre2

PDB 3odo chain A

Region: 761 - 986
Aligned: 221
Modelled: 226
Confidence: 100.0%
Identity: 21%
PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 1;
PDBTitle: crystal structure of the dh/ph domains of p115-rhogef

Phyre2

PDB 1xcg chain A

Region: 764 - 986
Aligned: 218
Modelled: 223
Confidence: 100.0%
Identity: 19%
PDB header:signaling protein activator/signaling pr
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 11;
PDBTitle: crystal structure of human rhoa in complex with dh/ph2 fragment of pdzrhogef

Phyre2

PDB 1x86 chain A

Region: 762 - 986
Aligned: 221
Modelled: 225
Confidence: 100.0%
Identity: 18%
PDB header:signaling protein/membrane protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 12;
PDBTitle: crystal structure of the dh/ph domains of leukemia-associated rhogef2 in complex with rhoa

Phyre2

PDB 1foe chain A

Region: 779 - 983
Aligned: 201
Modelled: 205
Confidence: 100.0%
Identity: 27%
PDB header:signaling protein, immune system/signali
Chain: A: PDB Molecule:t-lymphoma invasion and metastasis inducing
PDBTitle: crystal structure of rac1 in complex with the guanine2 nucleotide exchange region of tiam1

Phyre2

PDB 1gri chain A

Region: 6 - 204
Aligned: 192
Modelled: 199
Confidence: 100.0%
Identity: 24%
PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2

Phyre2

PDB 1xdv chain B

Region: 784 - 995
Aligned: 209
Modelled: 212
Confidence: 100.0%
Identity: 19%
PDB header:signaling protein
Chain: B: PDB Molecule:son of sevenless protein homolog 1;
PDBTitle: experimentally phased structure of human the son of2 sevenless protein at 4.1 ang.

Phyre2

PDB 3t06 chain E

Region: 763 - 986
Aligned: 219
Modelled: 224
Confidence: 100.0%
Identity: 19%
PDB header:signaling protein
Chain: E: PDB Molecule:rho guanine nucleotide exchange factor 11;
PDBTitle: crystal structure of the dh/ph fragment of pdzrhogef with n-terminal2 regulatory elements in complex with human rhoa

Phyre2

PDB 1xcg chain A domain 1

Region: 764 - 986
Aligned: 218
Modelled: 223
Confidence: 100.0%
Identity: 19%
Fold: DBL homology domain (DH-domain)
Superfamily: DBL homology domain (DH-domain)
Family: DBL homology domain (DH-domain)

Phyre2

PDB 2dfk chain A

Region: 773 - 986
Aligned: 209
Modelled: 214
Confidence: 100.0%
Identity: 29%
PDB header:cell cycle
Chain: A: PDB Molecule:collybistin ii;
PDBTitle: crystal structure of the cdc42-collybistin ii complex

Phyre2

PDB 3bji chain A

Region: 780 - 985
Aligned: 197
Modelled: 206
Confidence: 100.0%
Identity: 24%
PDB header:signaling protein
Chain: A: PDB Molecule:proto-oncogene vav;
PDBTitle: structural basis of promiscuous guanine nucleotide exchange2 by the t-cell essential vav1

Phyre2

PDB 1ki1 chain B

Region: 775 - 982
Aligned: 205
Modelled: 208
Confidence: 100.0%
Identity: 24%
PDB header:signaling protein
Chain: B: PDB Molecule:intersectin long form;
PDBTitle: guanine nucleotide exchange region of intersectin in2 complex with cdc42

Phyre2

PDB 1txd chain A domain 1

Region: 762 - 986
Aligned: 221
Modelled: 225
Confidence: 100.0%
Identity: 17%
Fold: DBL homology domain (DH-domain)
Superfamily: DBL homology domain (DH-domain)
Family: DBL homology domain (DH-domain)

Phyre2

PDB 1dbh chain A domain 1

Region: 781 - 983
Aligned: 200
Modelled: 203
Confidence: 100.0%
Identity: 19%
Fold: DBL homology domain (DH-domain)
Superfamily: DBL homology domain (DH-domain)
Family: DBL homology domain (DH-domain)

Phyre2

PDB 2z0q chain A

Region: 775 - 982
Aligned: 189
Modelled: 193
Confidence: 100.0%
Identity: 27%
PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 3;
PDBTitle: crystal structure of dh-ph domain of rhogef3(xpln)

Phyre2

PDB 2lqn chain A

Region: 2 - 209
Aligned: 177
Modelled: 177
Confidence: 100.0%
Identity: 21%
PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl

Phyre2

PDB 2l3s chain A

Region: 148 - 303
Aligned: 156
Modelled: 156
Confidence: 99.9%
Identity: 26%
PDB header:structural protein
Chain: A: PDB Molecule:autoinhibited crk protein;
PDBTitle: structure of the autoinhibited crk

Phyre2

PDB 2eyz chain A

Region: 137 - 309
Aligned: 173
Modelled: 173
Confidence: 99.9%
Identity: 24%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii

Phyre2

PDB 1ov3 chain A

Region: 148 - 300
Aligned: 125
Modelled: 125
Confidence: 99.9%
Identity: 27%
PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosol factor 1;
PDBTitle: structure of the p22phox-p47phox complex

Phyre2

PDB 1mv3 chain A

Region: 1380 - 1577
Aligned: 198
Modelled: 198
Confidence: 99.8%
Identity: 10%
PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc

Phyre2

PDB 4avm chain A

Region: 999 - 1207
Aligned: 207
Modelled: 207
Confidence: 99.8%
Identity: 23%
PDB header:protein binding
Chain: A: PDB Molecule:bridging integrator 2;
PDBTitle: crystal structure of the n-bar domain of human bridging2 integrator 2.

Phyre2

PDB 2fic chain A

Region: 1024 - 1207
Aligned: 182
Modelled: 182
Confidence: 99.8%
Identity: 21%
PDB header:endocytosis/exocytosis, membrane protein
Chain: A: PDB Molecule:bridging integrator 1;
PDBTitle: the crystal structure of the bar domain from human bin1/amphiphysin ii2 and its implications for molecular recognition

Phyre2

PDB 1uru chain A

Region: 1013 - 1207
Aligned: 193
Modelled: 191
Confidence: 99.7%
Identity: 23%
Fold: BAR/IMD domain-like
Superfamily: BAR/IMD domain-like
Family: BAR domain

Phyre2

PDB 1uru chain A

Region: 1013 - 1207
Aligned: 193
Modelled: 191
Confidence: 99.7%
Identity: 23%
PDB header:endocytosis
Chain: A: PDB Molecule:amphiphysin;
PDBTitle: amphiphysin bar domain from drosophila

Phyre2

PDB 3sog chain A

Region: 1023 - 1215
Aligned: 191
Modelled: 191
Confidence: 99.7%
Identity: 23%
PDB header:structural protein
Chain: A: PDB Molecule:amphiphysin;
PDBTitle: crystal structure of the bar domain of human amphiphysin, isoform 1

Phyre2

PDB 2rqr chain A

Region: 1461 - 1580
Aligned: 115
Modelled: 115
Confidence: 99.7%
Identity: 17%
PDB header:protein binding
Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator
PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex

Phyre2

PDB 2e5k chain A

Region: 1505 - 1580
Aligned: 76
Modelled: 76
Confidence: 99.6%
Identity: 18%
PDB header:protein binding
Chain: A: PDB Molecule:suppressor of t-cell receptor signaling 1;
PDBTitle: solution structure of sh3 domain in suppressor of t-cell2 receptor signaling 1

Phyre2

PDB 1ng2 chain A domain 2

Region: 1506 - 1578
Aligned: 69
Modelled: 69
Confidence: 99.6%
Identity: 23%
Fold: SH3-like barrel
Superfamily: SH3-domain
Family: SH3-domain

Phyre2

PDB 1bb9 chain A

Region: 1507 - 1578
Aligned: 72
Modelled: 72
Confidence: 99.6%
Identity: 17%
PDB header:transferase
Chain: A: PDB Molecule:amphiphysin 2;
PDBTitle: crystal structure of the sh3 domain from rat amphiphysin 2

Phyre2

PDB 1bb9 chain A

Region: 1507 - 1578
Aligned: 72
Modelled: 72
Confidence: 99.6%
Identity: 17%
Fold: SH3-like barrel
Superfamily: SH3-domain
Family: SH3-domain

Phyre2

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