PHYRE Protein Fold Recognition Server

Subscribe to Phyre at Google Groups

Email:

Visit Phyre at Google Groups

Protein Homology/analogY Recognition Engine V 2.0

Fold library entry viewer: c3ksyA_

Fold library id	PDB Header	Molecule	Title
c3ksyA_	PDB header: signaling protein	Chain: A: PDB Molecule: son of sevenless homolog 1;	PDBTitle: crystal structure of the histone domain, dh-ph unit, and2 catalytic unit of the ras activator son of sevenless (sos)

Links to external resources
Added to library: Sat Aug 28 19:50:06 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence L P Y E F F S E E N A P K W R G L L V P A L K K V Q G Q V H P T L E S N D D A L Q Y V E E L I L Q L L N M L C Q A Q P R S A S D V E E R V Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
S S
T T S S S S S
T T S B
T
S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence K S F P H P I D K W A I A D A Q S A I E K R K R R N P L S L P V E K I H P L L K E V L G Y K I D H Q V S V Y I V A V L E Y I S A D I L K L V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T T T
S S S
S S
S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence G N Y V R N I R H Y E I T K Q D I K V A M C A D K V L M D M F H T S G E Q T Y Y D L V K A F M A E I R Q Y I R E L N L I I K V F R E P F V S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
B
S S
T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence N S K L F S A N D V E N I F S R I V D I H E L S V K L L G H I E D T V E M T D E G S P H P L V G S C F E D L A E E L A F D P Y E S Y A R D I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T S
S S
S S S S S
T T T T S

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence L R P G F H D R F L S Q L S K P G A A L Y L Q S I G E G F K E A V Q Y V L P R L L L A P V Y H C L H Y F E L L K Q L E E K S E D Q E D K E C

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T T S S S T T
T T T T T S

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence L K Q A I T A L L N V Q S G M E K I C S K S L A K R R L S E S A A I K K M N E I Q K N I D G W E G K D I G Q C C N E F I M E G T L T R V G A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T S T T
S T S S S
S S
G G G T
S
T T

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480 . . . . . . . . . 490

Sequence K H E R H I F L F D G L M I C C K S N H G Q P R L P G A S N A E Y R L K E K F F M R K V Q I N D K D D T N E Y K H A F E I I L K D E N S V I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
T T
T T
T T S
S
S S
S S S
S
T T S

. . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540 . . . . . . . . . 550 . . . . . . . . . 560

Sequence F S A K S A E E K N N W M A A L I S L Q Y R S T L E R M L D V T M L Q E E K E E Q M R L P S A D V Y R F A E P D S E E N I I F E E N M Q P K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S
T T T
G G G S
T T T
S S S
S S

. . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600 . . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630

Sequence A G I P I I K A G T V I K L I E R L T Y H M Y A D P N F V R T F L T T Y R S F C K P Q E L L S L I I E R F E I P E P E P T E A D R I A I E N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T
S S
S
T T T S
T T S

. . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660 . . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700

Sequence G D Q P L S A E L K R F R K E Y I Q P V Q L R V L N V C R H W V E H H F Y D F E R D A Y L L Q R M E E F I G T V R G K A M K K W V E S I T K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
T T
T T

. . . . . . . . . 710 . . . . . . . . . 720 . . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770

Sequence I I Q R K K I A R D N H N I T F Q S S P P T V E W H I S R P G H I E T F D L L T L H P I E I A R Q L T L L E S D L Y R A V Q P S E L V G S V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S S
T T
T T T
T T T S
G G G G S S S T

. . . . . . . . . 780 . . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence W T K E D K E I N S P N L L K M I R H T T N L T L W F E K C I V E T E N L E E R V A V V S R I I E I L Q V F Q E L N N F N G V L E V V S A M

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S S
T
S T T

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900 . . . . . . . . . 910

Sequence N S S P V Y R L D H T F E Q I P S R Q K K I L E E A H E L S E D H Y K K Y L A K L R S I N P P C V P F F G I Y L T N I L K T E E G N P E V L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S T
T T T T T S S
T T T T T
S S
T S
S

. . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960 . . . . . . . . . 970 . . . . . . . . . 980

Sequence K R H G K E L I N F S K R R K V A E I T G E I Q Q Y Q N Q P Y C L R V E S D I K R F F E N L N P M G N S M E K E F T D Y L F N K S L E I E P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T T S S
S
T T T T S
S

. . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . .

Sequence R N P K P L P R F P K K Y S Y P L K S P G V R P S N P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S
S
S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Close JSmol

Interactive 3D view in JSmol

Phyre is now FREE for commercial users!

All images and data generated by Phyre2 are free to use in any publication with acknowledgement
Accessibility Statement

Please cite: The Phyre2 web portal for protein modeling, prediction and analysis

Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

Disclaimer

Terms and Conditions

Structural Biology Group logo Imperial logo

BBSRC logo
Phyre2 is part of Genome3D

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	L	P	Y	E	F	F	S	E	E	N	A	P	K	W	R	G	L	L	V	P	A	L	K	K	V	Q	G	Q	V	H	P	T	L	E	S	N	D	D	A	L	Q	Y	V	E	E	L	I	L	Q	L	L	N	M	L	C	Q	A	Q	P	R	S	A	S	D	V	E	E	R	V	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					S	S		S	S			T	T	S	S	S	S	S													T	T	S	B																							T				S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	K	S	F	P	H	P	I	D	K	W	A	I	A	D	A	Q	S	A	I	E	K	R	K	R	R	N	P	L	S	L	P	V	E	K	I	H	P	L	L	K	E	V	L	G	Y	K	I	D	H	Q	V	S	V	Y	I	V	A	V	L	E	Y	I	S	A	D	I	L	K	L	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S		T	T														T	T				S	S	S		S	S															S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	G	N	Y	V	R	N	I	R	H	Y	E	I	T	K	Q	D	I	K	V	A	M	C	A	D	K	V	L	M	D	M	F	H	T	S	G	E	Q	T	Y	Y	D	L	V	K	A	F	M	A	E	I	R	Q	Y	I	R	E	L	N	L	I	I	K	V	F	R	E	P	F	V	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							T	T			B														S	S																																					T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	N	S	K	L	F	S	A	N	D	V	E	N	I	F	S	R	I	V	D	I	H	E	L	S	V	K	L	L	G	H	I	E	D	T	V	E	M	T	D	E	G	S	P	H	P	L	V	G	S	C	F	E	D	L	A	E	E	L	A	F	D	P	Y	E	S	Y	A	R	D	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T	T	S										S	S																								S	S	S	S	S													T	T	T	T	S
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	L	R	P	G	F	H	D	R	F	L	S	Q	L	S	K	P	G	A	A	L	Y	L	Q	S	I	G	E	G	F	K	E	A	V	Q	Y	V	L	P	R	L	L	L	A	P	V	Y	H	C	L	H	Y	F	E	L	L	K	Q	L	E	E	K	S	E	D	Q	E	D	K	E	C
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T							T	T	S	S	S	T	T										T	T								T					T	T																			S
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	L	K	Q	A	I	T	A	L	L	N	V	Q	S	G	M	E	K	I	C	S	K	S	L	A	K	R	R	L	S	E	S	A	A	I	K	K	M	N	E	I	Q	K	N	I	D	G	W	E	G	K	D	I	G	Q	C	C	N	E	F	I	M	E	G	T	L	T	R	V	G	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T											T	T	S	T	T												S								T	S	S	S			S	S		G	G	G	T		S											T	T
	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490
Sequence	K	H	E	R	H	I	F	L	F	D	G	L	M	I	C	C	K	S	N	H	G	Q	P	R	L	P	G	A	S	N	A	E	Y	R	L	K	E	K	F	F	M	R	K	V	Q	I	N	D	K	D	D	T	N	E	Y	K	H	A	F	E	I	I	L	K	D	E	N	S	V	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S								T	T									T	T					T	T	S				S										S	S									S	S	S			S							T	T	S
	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
Sequence	F	S	A	K	S	A	E	E	K	N	N	W	M	A	A	L	I	S	L	Q	Y	R	S	T	L	E	R	M	L	D	V	T	M	L	Q	E	E	K	E	E	Q	M	R	L	P	S	A	D	V	Y	R	F	A	E	P	D	S	E	E	N	I	I	F	E	E	N	M	Q	P	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S	S																																			S							T	T	T		G	G	G	S				T	T	T					S	S	S		S	S
	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630
Sequence	A	G	I	P	I	I	K	A	G	T	V	I	K	L	I	E	R	L	T	Y	H	M	Y	A	D	P	N	F	V	R	T	F	L	T	T	Y	R	S	F	C	K	P	Q	E	L	L	S	L	I	I	E	R	F	E	I	P	E	P	E	P	T	E	A	D	R	I	A	I	E	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S																T		S	S													S		T	T	T	S																												T	T	S
	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700
Sequence	G	D	Q	P	L	S	A	E	L	K	R	F	R	K	E	Y	I	Q	P	V	Q	L	R	V	L	N	V	C	R	H	W	V	E	H	H	F	Y	D	F	E	R	D	A	Y	L	L	Q	R	M	E	E	F	I	G	T	V	R	G	K	A	M	K	K	W	V	E	S	I	T	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S			T	T																																																					T	T
	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770
Sequence	I	I	Q	R	K	K	I	A	R	D	N	H	N	I	T	F	Q	S	S	P	P	T	V	E	W	H	I	S	R	P	G	H	I	E	T	F	D	L	L	T	L	H	P	I	E	I	A	R	Q	L	T	L	L	E	S	D	L	Y	R	A	V	Q	P	S	E	L	V	G	S	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																		S									S	S		T	T		T	T	T			T	T	T	S																						G	G	G	G	S	S	S	T
	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	W	T	K	E	D	K	E	I	N	S	P	N	L	L	K	M	I	R	H	T	T	N	L	T	L	W	F	E	K	C	I	V	E	T	E	N	L	E	E	R	V	A	V	V	S	R	I	I	E	I	L	Q	V	F	Q	E	L	N	N	F	N	G	V	L	E	V	V	S	A	M
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	S	S																													T			S																					T	T
	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910
Sequence	N	S	S	P	V	Y	R	L	D	H	T	F	E	Q	I	P	S	R	Q	K	K	I	L	E	E	A	H	E	L	S	E	D	H	Y	K	K	Y	L	A	K	L	R	S	I	N	P	P	C	V	P	F	F	G	I	Y	L	T	N	I	L	K	T	E	E	G	N	P	E	V	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S					T		T	T	T	T	T	S	S													T	T	T												T	T			S	S					T														S		S
	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980
Sequence	K	R	H	G	K	E	L	I	N	F	S	K	R	R	K	V	A	E	I	T	G	E	I	Q	Q	Y	Q	N	Q	P	Y	C	L	R	V	E	S	D	I	K	R	F	F	E	N	L	N	P	M	G	N	S	M	E	K	E	F	T	D	Y	L	F	N	K	S	L	E	I	E	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T																					T	T	T	S	S																S			T	T	T	T	S																	S
	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.
Sequence	R	N	P	K	P	L	P	R	F	P	K	K	Y	S	Y	P	L	K	S	P	G	V	R	P	S	N	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S	S	S											S							S