Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionO88890
DateWed Jul 10 14:08:25 BST 2013
Unique Job ID8b2bbfb33b9c3421
SequenceMDAVTVYHGK ... Download FASTA

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:38.546 Y:33.667 Z:30.260
Model (left) based on template c1ka6A_
Top template information
PDB header:immune system
Chain: A: PDB Molecule:sh2 domain protein 1a;
PDBTitle: sap/sh2d1a bound to peptide n-py
Confidence and coverage
Confidence:100.0% Coverage: 84%
106 residues ( 84% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MDAVTVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYQGYIYTYRVSQTE
Secondary structure 
SS confidence 
Disorder  ??????
?
?
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  TGSWSAETAPGVHKRFFRKVKNLISAFQKPDQGIVTPLQYPVEKSSGRGPQAPTGRRDSD
Secondary structure 
SS confidence 
Disorder 
???
???????????
?
Disorder confidence 
 
   ......
Sequence  ICLNAP
Secondary structure 
SS confidence 
Disorder 
?????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered ( 22%)
Alpha helix ( 15%)
Beta strand ( 25%)

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1ka6 chain A

3D model

Region: 1 - 106
Aligned: 106
Modelled: 106
Confidence: 100.0%
Identity: 94%
PDB header:immune system
Chain: A: PDB Molecule:sh2 domain protein 1a;
PDBTitle: sap/sh2d1a bound to peptide n-py

Phyre2

PDB 1d4t chain A

3D model

Region: 1 - 104
Aligned: 104
Modelled: 104
Confidence: 100.0%
Identity: 95%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 1a81 chain E domain 1

3D model

Region: 1 - 112
Aligned: 107
Modelled: 112
Confidence: 100.0%
Identity: 26%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 2oq1 chain A domain 1

3D model

Region: 1 - 112
Aligned: 107
Modelled: 112
Confidence: 100.0%
Identity: 23%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 1i3z chain A

3D model

Region: 3 - 104
Aligned: 102
Modelled: 101
Confidence: 100.0%
Identity: 38%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 2ysx chain A

3D model

Region: 5 - 113
Aligned: 109
Modelled: 109
Confidence: 100.0%
Identity: 42%
PDB header:signaling protein
Chain: A: PDB Molecule:signaling inositol polyphosphate phosphatase
PDBTitle: solution structure of the human ship sh2 domain

Phyre2

PDB 2oq1 chain A

3D model

Region: 1 - 113
Aligned: 108
Modelled: 113
Confidence: 100.0%
Identity: 23%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide

Phyre2

PDB 2dly chain A

3D model

Region: 1 - 112
Aligned: 107
Modelled: 112
Confidence: 100.0%
Identity: 27%
PDB header:transferase
Chain: A: PDB Molecule:fyn-related kinase;
PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase

Phyre2

PDB 1a81 chain A domain 1

3D model

Region: 1 - 114
Aligned: 109
Modelled: 114
Confidence: 100.0%
Identity: 26%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 4fl2 chain A

3D model

Region: 1 - 113
Aligned: 108
Modelled: 113
Confidence: 100.0%
Identity: 26%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase syk;
PDBTitle: structural and biophysical characterization of the syk activation2 switch

Phyre2

PDB 2gsb chain A

3D model

Region: 1 - 112
Aligned: 106
Modelled: 112
Confidence: 99.9%
Identity: 25%
PDB header:signaling protein
Chain: A: PDB Molecule:ras gtpase-activating protein 1;
PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1

Phyre2

PDB 2oq1 chain A domain 2

3D model

Region: 2 - 104
Aligned: 97
Modelled: 103
Confidence: 99.9%
Identity: 26%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 1a81 chain E domain 2

3D model

Region: 2 - 104
Aligned: 97
Modelled: 103
Confidence: 99.9%
Identity: 31%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 2ozo chain A

3D model

Region: 3 - 113
Aligned: 106
Modelled: 111
Confidence: 99.9%
Identity: 24%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70

Phyre2

PDB 1blj chain A

3D model

Region: 1 - 106
Aligned: 101
Modelled: 106
Confidence: 99.9%
Identity: 25%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 1lkk chain A

3D model

Region: 1 - 103
Aligned: 98
Modelled: 103
Confidence: 99.9%
Identity: 26%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 2eo6 chain A

3D model

Region: 1 - 109
Aligned: 109
Modelled: 109
Confidence: 99.9%
Identity: 25%
PDB header:signaling protein
Chain: A: PDB Molecule:b-cell linker protein;
PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk

Phyre2

PDB 1csy chain A

3D model

Region: 1 - 106
Aligned: 100
Modelled: 101
Confidence: 99.9%
Identity: 30%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 1a81 chain A domain 2

3D model

Region: 2 - 104
Aligned: 97
Modelled: 103
Confidence: 99.9%
Identity: 31%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 2ge9 chain A

3D model

Region: 1 - 112
Aligned: 106
Modelled: 112
Confidence: 99.9%
Identity: 27%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase btk;
PDBTitle: solution structures of the sh2 domain of bruton's tyrosine2 kinase

Phyre2
1
c1ka6A_
2
d1d4ta_
3
d1a81e1
4
d2oq1a1
5
d1i3za_
6
c2ysxA_
7
c2oq1A_
8
c2dlyA_
9
d1a81a1
10
c4fl2A_
11
c2gsbA_
12
d2oq1a2
13
d1a81e2
14
c2ozoA_
15
d1blja_
16
d1lkka_
17
c2eo6A_
18
d1csya_
19
d1a81a2
20
c2ge9A_
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
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113
114
115
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117
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128
129
130
131
132



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1ka6A_
100.0 94 PDB header:immune system
Chain: A: PDB Molecule:sh2 domain protein 1a;
PDBTitle: sap/sh2d1a bound to peptide n-py
2d1d4ta_
100.0 95 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
3d1a81e1
100.0 26 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
4d2oq1a1
100.0 23 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
5d1i3za_
100.0 38 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
6c2ysxA_
100.0 42 PDB header:signaling protein
Chain: A: PDB Molecule:signaling inositol polyphosphate phosphatase
PDBTitle: solution structure of the human ship sh2 domain
7c2oq1A_
100.0 23 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide
8c2dlyA_
100.0 27 PDB header:transferase
Chain: A: PDB Molecule:fyn-related kinase;
PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase
9d1a81a1
100.0 26 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
10c4fl2A_
100.0 26 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase syk;
PDBTitle: structural and biophysical characterization of the syk activation2 switch
11c2gsbA_
99.9 25 PDB header:signaling protein
Chain: A: PDB Molecule:ras gtpase-activating protein 1;
PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1
12d2oq1a2
99.9 26 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
13d1a81e2
99.9 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
14c2ozoA_
99.9 24 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70
15d1blja_
99.9 25 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
16d1lkka_
99.9 26 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
17c2eo6A_
99.9 25 PDB header:signaling protein
Chain: A: PDB Molecule:b-cell linker protein;
PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk
18d1csya_
99.9 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
19d1a81a2
99.9 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
20c2ge9A_
99.9 27 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase btk;
PDBTitle: solution structures of the sh2 domain of bruton's tyrosine2 kinase
21d1rjaa_
not modelled 99.9 23 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
22d1opka2
not modelled 99.9 33 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
23c2augB_
not modelled 99.9 23 PDB header:signaling protein
Chain: B: PDB Molecule:growth factor receptor-bound protein 14;
PDBTitle: crystal structure of the grb14 sh2 domain
24d1k9aa2
not modelled 99.9 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
25d1nrva_
not modelled 99.9 25 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
26d1jwoa_
not modelled 99.9 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
27d1o48a_
not modelled 99.9 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
28d2shpa2
not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
29c2ablA_
not modelled 99.9 33 PDB header:transferase
Chain: A: PDB Molecule:abl tyrosine kinase;
PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase
30d1qcfa2
not modelled 99.9 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
31d1f2fa_
not modelled 99.9 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
32c2fo0A_
not modelled 99.9 30 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
33d2qmsa1
not modelled 99.9 24 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
34c1a81E_
not modelled 99.9 27 PDB header:complex (transferase/peptide)
Chain: E: PDB Molecule:syk kinase;
PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam
35d1luia_
not modelled 99.9 34 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
36c2eobA_
not modelled 99.9 20 PDB header:hydrolase
Chain: A: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate
PDBTitle: solution structure of the second sh2 domain from rat plc2 gamma-2
37d3c7ia1
not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
38d1fhsa_
not modelled 99.9 22 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
39c2dm0A_
not modelled 99.9 25 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase txk;
PDBTitle: solution structure of the sh2 domain of human tyrosine-2 protein kinase txk
40d1g83a2
not modelled 99.9 26 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
41c3hizB_
not modelled 99.9 27 PDB header:transferase/oncoprotein
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit
PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha
42d1bkla_
not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
43c2ekxA_
not modelled 99.9 28 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic tyrosine-protein kinase bmx;
PDBTitle: solution structure of the human bmx sh2 domain
44c1x27F_
not modelled 99.9 23 PDB header:signaling protein
Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck;
PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas
45c2eo3A_
not modelled 99.9 24 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of the sh2 domain from human crk-like2 protein
46c1y57A_
not modelled 99.9 25 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
47c3nhnA_
not modelled 99.9 28 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region
48c2lqnA_
not modelled 99.9 19 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl
49d2izva2
not modelled 99.9 20 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
50c2hdxB_
not modelled 99.9 24 PDB header:signaling protein
Chain: B: PDB Molecule:sh2-b ph domain containing signaling mediator 1
PDBTitle: crystal structure of the src homology-2 domain of sh2-b in2 complex with jak2 ptyr813 phosphopeptide
51c1oplA_
not modelled 99.9 30 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
52c1x6cA_
not modelled 99.9 27 PDB header:signaling protein
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: solution structures of the sh2 domain of human protein-2 tyrosine phosphatase shp-1
53c2y3aB_
not modelled 99.9 31 PDB header:transferase
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta;
PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
54c2shpA_
not modelled 99.9 26 PDB header:tyrosine phosphatase
Chain: A: PDB Molecule:shp-2;
PDBTitle: tyrosine phosphatase shp-2
55c2crhA_
not modelled 99.9 23 PDB header:signaling protein
Chain: A: PDB Molecule:vav proto-oncogene;
PDBTitle: solution structure of the sh2 domain of human proto-2 oncogene protein vav1
56c2h8hA_
not modelled 99.9 25 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor
57d2fcia1
not modelled 99.9 24 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
58c2c9wA_
not modelled 99.9 18 PDB header:transcription regulation
Chain: A: PDB Molecule:suppressor of cytokine signaling 2;
PDBTitle: crystal structure of socs-2 in complex with elongin-b and2 elongin-c at 1.9a resolution
59c2dlzA_
not modelled 99.9 20 PDB header:signaling protein
Chain: A: PDB Molecule:protein vav-2;
PDBTitle: solution structure of the sh2 domain of human protein vav-2
60d1pica_
not modelled 99.9 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
61c2el8A_
not modelled 99.9 15 PDB header:signaling protein
Chain: A: PDB Molecule:signal-transducing adaptor protein 2;
PDBTitle: solution structure of the human stap2 sh2 domain
62c2hmhA_
not modelled 99.9 19 PDB header:cytokine regulator
Chain: A: PDB Molecule:suppressor of cytokine signaling 3;
PDBTitle: crystal structure of socs3 in complex with gp130(ptyr757)2 phosphopeptide.
63c3mazA_
not modelled 99.9 18 PDB header:signaling protein
Chain: A: PDB Molecule:signal-transducing adaptor protein 1;
PDBTitle: crystal structure of the human brdg1/stap-1 sh2 domain in complex with2 the ntal ptyr136 peptide
64c2c0iA_
not modelled 99.9 25 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983
65d1ayaa_
not modelled 99.9 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
66c2knoA_
not modelled 99.9 22 PDB header:hydrolase
Chain: A: PDB Molecule:tensin-like c1 domain-containing phosphatase;
PDBTitle: nmr solution structure of sh2 domain of the human tensin like c12 domain containing phosphatase (tenc1)
67c2lctA_
not modelled 99.9 23 PDB header:signaling protein
Chain: A: PDB Molecule:proto-oncogene vav;
PDBTitle: solution structure of the vav1 sh2 domain complexed with a syk-derived2 doubly phosphorylated peptide
68c1k9aB_
not modelled 99.9 30 PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
69c2ci8A_
not modelled 99.9 28 PDB header:translation
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: sh2 domain of human nck1 adaptor protein - uncomplexed
70c2vifA_
not modelled 99.9 24 PDB header:signaling protein
Chain: A: PDB Molecule:suppressor of cytokine signalling 6;
PDBTitle: crystal structure of socs6 sh2 domain in complex with a c-kit2 phosphopeptide
71d2cs0a1
not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
72d2eyva1
not modelled 99.9 24 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
73c3ps5A_
not modelled 99.9 20 PDB header:hydrolase, signaling protein
Chain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 6;
PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1
74c2izvA_
not modelled 99.9 19 PDB header:transcription
Chain: A: PDB Molecule:suppressor of cytokine signaling 4;
PDBTitle: crystal structure of socs-4 in complex with elongin-b and2 elongin-c at 2.55a resolution
75c2b3oA_
not modelled 99.9 20 PDB header:hydrolase
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: crystal structure of human tyrosine phosphatase shp-1
76d1jyra_
not modelled 99.9 24 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
77d2shpa3
not modelled 99.9 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
78c2kk6A_
not modelled 99.9 27 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fer;
PDBTitle: solution structure of sh2 domain of proto-oncogene tyrosine-2 protein kinase fer from homo sapiens, northeast structural3 genomics consortium (nesg) target hr3461d
79c3gqiB_
not modelled 99.9 26 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:phospholipase c-gamma-1;
PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates
80d1mila_
not modelled 99.9 34 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
81d1cwea_
not modelled 99.9 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
82c1g83A_
not modelled 99.9 26 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn;
PDBTitle: crystal structure of fyn sh3-sh2
83d1r1qa_
not modelled 99.9 21 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
84d1fu6a_
not modelled 99.9 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
85d1qada_
not modelled 99.9 33 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
86c2dcrA_
not modelled 99.9 25 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: fully automated solution structure determination of the fes2 sh2 domain
87d1rpya_
not modelled 99.9 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
88d2c9wa2
not modelled 99.9 16 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
89c1rqqC_
not modelled 99.8 29 PDB header:transferase/signaling protein
Chain: C: PDB Molecule:adaptor protein aps;
PDBTitle: crystal structure of the insulin receptor kinase in complex2 with the sh2 domain of aps
90c2eyzA_
not modelled 99.8 21 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii
91d1xa6a2
not modelled 99.8 25 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
92c2dvjA_
not modelled 99.8 19 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog,
PDBTitle: phosphorylated crk-ii
93c3qwxX_
not modelled 99.7 24 PDB header:signaling protein
Chain: X: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2 1-174
94c2eyyA_
not modelled 99.7 20 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i
95c3qwyA_
not modelled 99.7 25 PDB header:signaling protein
Chain: A: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2
96c3gxxB_
not modelled 99.7 12 PDB header:transcription
Chain: B: PDB Molecule:transcription elongation factor spt6;
PDBTitle: structure of the sh2 domain of the candida glabrata2 transcription elongation factor spt6, crystal form b
97c2cr4A_
not modelled 99.7 19 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 domain-binding protein 2;
PDBTitle: solution structure of the sh2 domain of human sh3bp2 protein
98c2dx0B_
not modelled 99.7 26 PDB header:hydrolase
Chain: B: PDB Molecule:phospholipase c, gamma 2;
PDBTitle: crystal structure of the n-terminal sh2 domain of mouse2 phospholipase c-gamma 2
99c3or8A_
not modelled 99.6 11 PDB header:transcription
Chain: A: PDB Molecule:transcription elongation factor spt6;
PDBTitle: a tandem sh2 domain in transcription elongation factor spt6
100c2xp1A_
not modelled 99.6 14 PDB header:transcription
Chain: A: PDB Molecule:spt6;
PDBTitle: structure of the tandem sh2 domains from antonospora locustae2 transcription elongation factor spt6
101d1bf5a3
not modelled 99.5 21 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
102c1xa6A_
not modelled 99.4 34 PDB header:signaling protein
Chain: A: PDB Molecule:beta2-chimaerin;
PDBTitle: crystal structure of the human beta2-chimaerin
103d1uura3
not modelled 99.4 25 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
104d1bg1a3
not modelled 99.2 21 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
105c3cblA_
not modelled 99.1 28 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: crystal structure of human feline sarcoma viral oncogene homologue (v-2 fes) in complex with staurosporine and a consensus peptide
106c2cblA_
not modelled 98.2 14 PDB header:complex (proto-oncogene/peptide)
Chain: A: PDB Molecule:proto-oncogene cbl;
PDBTitle: n-terminal domain of cbl in complex with its binding site2 on zap-70
107c3bunB_
not modelled 98.2 14 PDB header:ligase/signaling protein
Chain: B: PDB Molecule:e3 ubiquitin-protein ligase cbl;
PDBTitle: crystal structure of c-cbl-tkb domain complexed with its2 binding motif in sprouty4
108c1uusA_
not modelled 98.1 19 PDB header:signal transduction
Chain: A: PDB Molecule:stat protein;
PDBTitle: structure of an activated dictyostelium stat in its2 dna-unbound form
109c1y1uA_
not modelled 97.9 27 PDB header:signaling protein
Chain: A: PDB Molecule:signal transducer and activator of transcription 5a;
PDBTitle: structure of unphosphorylated stat5a
110c1bg1A_
not modelled 97.7 22 PDB header:transcription/dna
Chain: A: PDB Molecule:protein (transcription factor stat3b);
PDBTitle: transcription factor stat3b/dna complex
111c1yvlB_
not modelled 97.7 32 PDB header:signaling protein
Chain: B: PDB Molecule:signal transducer and activator of transcription
PDBTitle: structure of unphosphorylated stat1
112c1bf5A_
not modelled 97.6 33 PDB header:gene regulation/dna
Chain: A: PDB Molecule:signal transducer and activator of transcription
PDBTitle: tyrosine phosphorylated stat-1/dna complex
113c3cwgA_
not modelled 96.2 34 PDB header:transcription
Chain: A: PDB Molecule:signal transducer and activator of transcription
PDBTitle: unphosphorylated mouse stat3 core fragment
114c1fbvA_
not modelled 94.0 14 PDB header:ligase
Chain: A: PDB Molecule:signal transduction protein cbl;
PDBTitle: structure of a cbl-ubch7 complex: ring domain function in2 ubiquitin-protein ligases
115d3buxb3
not modelled 91.8 14 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
116c3op0B_
not modelled 87.0 16 PDB header:signaling protein/signaling protein regu
Chain: B: PDB Molecule:signal transduction protein cbl-c;
PDBTitle: crystal structure of cbl-c (cbl-3) tkb domain in complex with egfr2 py1069 peptide
117c1griA_
not modelled 80.4 21 PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2
118c1x60A_
not modelled 35.7 17 PDB header:hydrolase
Chain: A: PDB Molecule:sporulation-specific n-acetylmuramoyl-l-alanine
PDBTitle: solution structure of the peptidoglycan binding domain of2 b. subtilis cell wall lytic enzyme cwlc
119d1wlha1
not modelled 34.9 21 Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:Filamin repeat (rod domain)
120c1ksrA_
not modelled 33.3 21 PDB header:actin binding protein
Chain: A: PDB Molecule:gelation factor;
PDBTitle: the repeating segments of the f-actin cross-linking2 gelation factor (abp-120) have an immunoglobulin fold, nmr,3 20 structures

Binding site prediction 

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