Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	Q	N	N	P	L	R	A	L	L	D	K	Q	D	I	L	L	L	D	G	A	M	A	T	E	L	E	A	R	G	C	N	L	A	D	S	L	W	S	A	K	V	L	V	E	N	P	E	L	I	R	E	V	H	L	D	Y	Y	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	G	A	Q	C	A	I	T	A	S	Y	Q	A	T	P	A	G	F	A	A	R	G	L	D	E	A	Q	S	K	A	L	I	G	K	S	V	E	L	A	R	K	A	R	E	A	Y	L	A	E	N	P	Q	A	G	T	L	L	V	A	G
Secondary structure
SS confidence
Disorder																									?																									?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		S	V	G	P	Y	G	A	Y	L	A	D	G	S	E	Y	R	G	D	Y	H	C	S	V	E	A	F	Q	A	F	H	R	P	R	V	E	A	L	L	D	A	G	A	D	L	L	A	C	E	T	L	P	N	F	S	E	I	E	A	L	A
Secondary structure
SS confidence
Disorder										?	?			?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		E	L	L	T	A	Y	P	R	A	R	A	W	F	S	F	T	L	R	D	S	E	H	L	S	D	G	T	P	L	R	D	V	V	A	L	L	A	G	Y	P	Q	V	V	A	L	G	I	N	C	I	A	L	E	N	T	T	A	A	L	Q
Secondary structure
SS confidence
Disorder																						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		H	L	H	G	L	T	V	L	P	L	V	V	Y	P	N	S	G	E	H	Y	D	A	V	S	K	T	W	H	H	H	G	E	H	C	A	Q	L	A	D	Y	L	P	Q	W	Q	A	A	G	A	R	L	I	G	G	C	C	R	T	T	P
Secondary structure
SS confidence
Disorder																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310
Sequence		A	D	I	A	A	L	K	A	R	S
Secondary structure
SS confidence
Disorder										?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3bof chain A domain 2 Region: 1 - 309 Aligned: 284 Modelled: 299 Confidence: 100.0% Identity: 27% Fold: TIM beta/alpha-barrel Superfamily: Homocysteine S-methyltransferase Family: Homocysteine S-methyltransferase Phyre2 PDB 3bol chain B Region: 1 - 309 Aligned: 274 Modelled: 299 Confidence: 100.0% Identity: 27% PDB header:transferase Chain: B: PDB Molecule:5-methyltetrahydrofolate s-homocysteine PDBTitle: cobalamin-dependent methionine synthase (1-566) from2 thermotoga maritima complexed with zn2+ Phyre2 PDB 1umy chain A Region: 4 - 309 Aligned: 273 Modelled: 306 Confidence: 100.0% Identity: 23% Fold: TIM beta/alpha-barrel Superfamily: Homocysteine S-methyltransferase Family: Homocysteine S-methyltransferase Phyre2 PDB 1lt7 chain A Region: 7 - 309 Aligned: 249 Modelled: 283 Confidence: 100.0% Identity: 26% Fold: TIM beta/alpha-barrel Superfamily: Homocysteine S-methyltransferase Family: Homocysteine S-methyltransferase Phyre2 PDB 3eoo chain L Region: 1 - 196 Aligned: 157 Modelled: 179 Confidence: 94.2% Identity: 17% PDB header:lyase Chain: L: PDB Molecule:methylisocitrate lyase; PDBTitle: 2.9a crystal structure of methyl-isocitrate lyase from2 burkholderia pseudomallei Phyre2 PDB 3lye chain A Region: 1 - 205 Aligned: 161 Modelled: 185 Confidence: 93.7% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:oxaloacetate acetyl hydrolase; PDBTitle: crystal structure of oxaloacetate acetylhydrolase Phyre2 PDB 1mum chain A Region: 46 - 196 Aligned: 119 Modelled: 134 Confidence: 93.7% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: Phosphoenolpyruvate mutase/Isocitrate lyase-like Phyre2 PDB 1zuw chain A Region: 11 - 167 Aligned: 148 Modelled: 157 Confidence: 93.4% Identity: 15% PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase 1; PDBTitle: crystal structure of b.subtilis glutamate racemase (race) with d-glu Phyre2 PDB 3h5d chain D Region: 125 - 305 Aligned: 171 Modelled: 177 Confidence: 91.2% Identity: 15% PDB header:lyase Chain: D: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: dihydrodipicolinate synthase from drug-resistant streptococcus2 pneumoniae Phyre2 PDB 2ekc chain A Region: 47 - 252 Aligned: 163 Modelled: 186 Confidence: 90.4% Identity: 17% PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5 Phyre2 PDB 1h1y chain A Region: 150 - 308 Aligned: 149 Modelled: 159 Confidence: 89.5% Identity: 11% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: D-ribulose-5-phosphate 3-epimerase Phyre2 PDB 2a6n chain A domain 1 Region: 126 - 255 Aligned: 117 Modelled: 130 Confidence: 88.5% Identity: 12% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 3fa4 chain D Region: 1 - 196 Aligned: 152 Modelled: 179 Confidence: 88.4% Identity: 16% PDB header:lyase Chain: D: PDB Molecule:2,3-dimethylmalate lyase; PDBTitle: crystal structure of 2,3-dimethylmalate lyase, a pep mutase/isocitrate2 lyase superfamily member, triclinic crystal form Phyre2 PDB 3dz1 chain A Region: 126 - 309 Aligned: 158 Modelled: 184 Confidence: 88.2% Identity: 9% PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 rhodopseudomonas palustris at 1.87a resolution Phyre2 PDB 1f61 chain A Region: 47 - 245 Aligned: 186 Modelled: 191 Confidence: 88.2% Identity: 18% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: Phosphoenolpyruvate mutase/Isocitrate lyase-like Phyre2 PDB 1m3u chain A Region: 46 - 192 Aligned: 107 Modelled: 114 Confidence: 87.3% Identity: 26% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: Ketopantoate hydroxymethyltransferase PanB Phyre2 PDB 1s2w chain A Region: 1 - 193 Aligned: 151 Modelled: 193 Confidence: 86.8% Identity: 17% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: Phosphoenolpyruvate mutase/Isocitrate lyase-like Phyre2 PDB 1ujq chain A Region: 152 - 205 Aligned: 50 Modelled: 54 Confidence: 86.7% Identity: 28% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: Phosphoenolpyruvate mutase/Isocitrate lyase-like Phyre2 PDB 3cpr chain B Region: 126 - 255 Aligned: 117 Modelled: 130 Confidence: 86.2% Identity: 18% PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthetase; PDBTitle: the crystal structure of corynebacterium glutamicum2 dihydrodipicolinate synthase to 2.2 a resolution Phyre2 PDB 2ze3 chain A Region: 46 - 193 Aligned: 119 Modelled: 124 Confidence: 86.0% Identity: 26% PDB header:isomerase Chain: A: PDB Molecule:dfa0005; PDBTitle: crystal structure of dfa0005 complexed with alpha-ketoglutarate: a2 novel member of the icl/pepm superfamily from alkali-tolerant3 deinococcus ficus Phyre2 1 d3bofa2 2 c3bolB_ 3 d1umya_ 4 d1lt7a_ 5 c3eooL_ 6 c3lyeA_ 7 d1muma_ 8 c1zuwA_ 9 c3h5dD_ 10 c2ekcA_ 11 d1h1ya_ 12 d2a6na1 13 c3fa4D_ 14 c3dz1A_ 15 d1f61a_ 16 d1m3ua_ 17 d1s2wa_ 18 d1ujqa_ 19 c3cprB_ 20 c2ze3A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d3bofa2 100.0 27 Fold:TIM beta/alpha-barrel Superfamily:Homocysteine S-methyltransferase Family:Homocysteine S-methyltransferase 2 c3bolB_ 100.0 27 PDB header:transferase Chain: B: PDB Molecule:5-methyltetrahydrofolate s-homocysteine PDBTitle: cobalamin-dependent methionine synthase (1-566) from2 thermotoga maritima complexed with zn2+ 3 d1umya_ 100.0 23 Fold:TIM beta/alpha-barrel Superfamily:Homocysteine S-methyltransferase Family:Homocysteine S-methyltransferase 4 d1lt7a_ 100.0 26 Fold:TIM beta/alpha-barrel Superfamily:Homocysteine S-methyltransferase Family:Homocysteine S-methyltransferase 5 c3eooL_ 94.2 17 PDB header:lyase Chain: L: PDB Molecule:methylisocitrate lyase; PDBTitle: 2.9a crystal structure of methyl-isocitrate lyase from2 burkholderia pseudomallei 6 c3lyeA_ 93.7 17 PDB header:hydrolase Chain: A: PDB Molecule:oxaloacetate acetyl hydrolase; PDBTitle: crystal structure of oxaloacetate acetylhydrolase 7 d1muma_ 93.7 15 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 8 c1zuwA_ 93.4 15 PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase 1; PDBTitle: crystal structure of b.subtilis glutamate racemase (race) with d-glu 9 c3h5dD_ 91.2 15 PDB header:lyase Chain: D: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: dihydrodipicolinate synthase from drug-resistant streptococcus2 pneumoniae 10 c2ekcA_ 90.4 17 PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5 11 d1h1ya_ 89.5 11 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 12 d2a6na1 88.5 12 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 13 c3fa4D_ 88.4 16 PDB header:lyase Chain: D: PDB Molecule:2,3-dimethylmalate lyase; PDBTitle: crystal structure of 2,3-dimethylmalate lyase, a pep mutase/isocitrate2 lyase superfamily member, triclinic crystal form 14 c3dz1A_ 88.2 9 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 rhodopseudomonas palustris at 1.87a resolution 15 d1f61a_ 88.2 18 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 16 d1m3ua_ 87.3 26 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Ketopantoate hydroxymethyltransferase PanB 17 d1s2wa_ 86.8 17 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 18 d1ujqa_ 86.7 28 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 19 c3cprB_ 86.2 18 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthetase; PDBTitle: the crystal structure of corynebacterium glutamicum2 dihydrodipicolinate synthase to 2.2 a resolution 20 c2ze3A_ 86.0 26 PDB header:isomerase Chain: A: PDB Molecule:dfa0005; PDBTitle: crystal structure of dfa0005 complexed with alpha-ketoglutarate: a2 novel member of the icl/pepm superfamily from alkali-tolerant3 deinococcus ficus 21 d1oy0a_ not modelled 84.6 18 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Ketopantoate hydroxymethyltransferase PanB 22 c2dwuA_ not modelled 84.6 21 PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of glutamate racemase isoform race1 from bacillus2 anthracis 23 d1tqxa_ not modelled 84.5 14 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 24 c3lciA_ not modelled 83.3 19 PDB header:lyase Chain: A: PDB Molecule:n-acetylneuraminate lyase; PDBTitle: the d-sialic acid aldolase mutant v251w 25 c3ih1A_ not modelled 83.2 18 PDB header:lyase Chain: A: PDB Molecule:methylisocitrate lyase; PDBTitle: crystal structure of carboxyvinyl-carboxyphosphonate phosphorylmutase2 from bacillus anthracis 26 c3kruC_ not modelled 82.6 10 PDB header:oxidoreductase Chain: C: PDB Molecule:nadh:flavin oxidoreductase/nadh oxidase; PDBTitle: crystal structure of the thermostable old yellow enzyme from2 thermoanaerobacter pseudethanolicus e39 27 c3s5oA_ not modelled 82.5 9 PDB header:lyase Chain: A: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase, mitochondrial; PDBTitle: crystal structure of human 4-hydroxy-2-oxoglutarate aldolase bound to2 pyruvate 28 c1jvnB_ not modelled 82.4 16 PDB header:transferase Chain: B: PDB Molecule:bifunctional histidine biosynthesis protein hishf; PDBTitle: crystal structure of imidazole glycerol phosphate synthase: a tunnel2 through a (beta/alpha)8 barrel joins two active sites 29 d1gvfa_ not modelled 82.2 16 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class II FBP aldolase 30 c2hmcA_ not modelled 81.8 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: the crystal structure of dihydrodipicolinate synthase dapa from2 agrobacterium tumefaciens 31 c3g0sA_ not modelled 80.6 13 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: dihydrodipicolinate synthase from salmonella typhimurium lt2 32 d1vhna_ not modelled 79.9 15 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 33 c1zlpA_ not modelled 78.1 14 PDB header:lyase Chain: A: PDB Molecule:petal death protein; PDBTitle: petal death protein psr132 with cysteine-linked glutaraldehyde forming2 a thiohemiacetal adduct 34 c3lerA_ not modelled 77.4 11 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 campylobacter jejuni subsp. jejuni nctc 11168 35 c2p10D_ not modelled 75.8 25 PDB header:hydrolase Chain: D: PDB Molecule:mll9387 protein; PDBTitle: crystal structure of a putative phosphonopyruvate hydrolase (mll9387)2 from mesorhizobium loti maff303099 at 2.15 a resolution 36 d1w3ia_ not modelled 75.7 16 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 37 d1pv8a_ not modelled 75.7 29 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 38 d1o66a_ not modelled 74.9 14 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Ketopantoate hydroxymethyltransferase PanB 39 c1zfjA_ not modelled 73.7 20 PDB header:oxidoreductase Chain: A: PDB Molecule:inosine monophosphate dehydrogenase; PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes 40 c3inpA_ not modelled 72.8 14 PDB header:isomerase Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase; PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis. 41 c3b8iF_ not modelled 72.6 23 PDB header:lyase Chain: F: PDB Molecule:pa4872 oxaloacetate decarboxylase; PDBTitle: crystal structure of oxaloacetate decarboxylase from pseudomonas2 aeruginosa (pa4872) in complex with oxalate and mg2+. 42 c2r94B_ not modelled 71.8 13 PDB header:lyase Chain: B: PDB Molecule:2-keto-3-deoxy-(6-phospho-)gluconate aldolase; PDBTitle: crystal structure of kd(p)ga from t.tenax 43 c3si9B_ not modelled 71.3 12 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from bartonella2 henselae 44 c2vc6A_ not modelled 70.3 17 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: structure of mosa from s. meliloti with pyruvate bound 45 c2gzmB_ not modelled 70.3 19 PDB header:isomerase Chain: B: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of the glutamate racemase from bacillus2 anthracis 46 c2y0fD_ not modelled 69.7 17 PDB header:oxidoreductase Chain: D: PDB Molecule:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; PDBTitle: structure of gcpe (ispg) from thermus thermophilus hb27 47 c3hfrA_ not modelled 69.5 17 PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of glutamate racemase from listeria monocytogenes 48 c2a4aB_ not modelled 68.9 21 PDB header:lyase Chain: B: PDB Molecule:deoxyribose-phosphate aldolase; PDBTitle: deoxyribose-phosphate aldolase from p. yoelii 49 c3qyqC_ not modelled 68.7 17 PDB header:lyase Chain: C: PDB Molecule:deoxyribose-phosphate aldolase, putative; PDBTitle: 1.8 angstrom resolution crystal structure of a putative deoxyribose-2 phosphate aldolase from toxoplasma gondii me49 50 c1ps9A_ not modelled 68.2 14 PDB header:oxidoreductase Chain: A: PDB Molecule:2,4-dienoyl-coa reductase; PDBTitle: the crystal structure and reaction mechanism of e. coli 2,4-2 dienoyl coa reductase 51 d1a3xa2 not modelled 68.0 15 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 52 d1p1xa_ not modelled 67.9 23 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 53 c3b0vD_ not modelled 67.2 21 PDB header:oxidoreductase/rna Chain: D: PDB Molecule:trna-dihydrouridine synthase; PDBTitle: trna-dihydrouridine synthase from thermus thermophilus in complex with2 trna 54 d1qopa_ not modelled 66.8 16 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 55 c3qz6A_ not modelled 66.6 14 PDB header:lyase Chain: A: PDB Molecule:hpch/hpai aldolase; PDBTitle: the crystal structure of hpch/hpai aldolase from desulfitobacterium2 hafniense dcb-2 56 c2y85D_ not modelled 64.3 16 PDB header:isomerase Chain: D: PDB Molecule:phosphoribosyl isomerase a; PDBTitle: crystal structure of mycobacterium tuberculosis phosphoribosyl2 isomerase with bound rcdrp 57 d2a4aa1 not modelled 63.1 17 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 58 d1pkla2 not modelled 62.9 12 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 59 d2flia1 not modelled 62.7 12 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 60 d1xcfa_ not modelled 62.6 14 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 61 d1ad1a_ not modelled 62.2 19 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 62 c3b4uB_ not modelled 61.9 13 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from agrobacterium2 tumefaciens str. c58 63 c3js3C_ not modelled 61.3 14 PDB header:lyase Chain: C: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: crystal structure of type i 3-dehydroquinate dehydratase (arod) from2 clostridium difficile with covalent reaction intermediate 64 c3qc3B_ not modelled 60.5 13 PDB header:isomerase Chain: B: PDB Molecule:d-ribulose-5-phosphate-3-epimerase; PDBTitle: crystal structure of a d-ribulose-5-phosphate-3-epimerase (np_954699)2 from homo sapiens at 2.20 a resolution 65 c3ct7E_ not modelled 58.0 14 PDB header:isomerase Chain: E: PDB Molecule:d-allulose-6-phosphate 3-epimerase; PDBTitle: crystal structure of d-allulose 6-phosphate 3-epimerase2 from escherichia coli k-12 66 c3ez4B_ not modelled 54.0 13 PDB header:transferase Chain: B: PDB Molecule:3-methyl-2-oxobutanoate hydroxymethyltransferase; PDBTitle: crystal structure of 3-methyl-2-oxobutanoate2 hydroxymethyltransferase from burkholderia pseudomallei 67 c2hjpA_ not modelled 53.9 23 PDB header:hydrolase Chain: A: PDB Molecule:phosphonopyruvate hydrolase; PDBTitle: crystal structure of phosphonopyruvate hydrolase complex with2 phosphonopyruvate and mg++ 68 d16pka_ not modelled 53.7 30 Fold:Phosphoglycerate kinase Superfamily:Phosphoglycerate kinase Family:Phosphoglycerate kinase 69 d1ka9f_ not modelled 53.6 14 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Histidine biosynthesis enzymes 70 d1jvna1 not modelled 53.3 14 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Histidine biosynthesis enzymes 71 d1xk7a1 not modelled 52.5 19 Fold:CoA-transferase family III (CaiB/BaiF) Superfamily:CoA-transferase family III (CaiB/BaiF) Family:CoA-transferase family III (CaiB/BaiF) 72 c3fluD_ not modelled 52.5 16 PDB header:lyase Chain: D: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from the pathogen2 neisseria meningitidis 73 d2fdsa1 not modelled 51.9 8 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase 74 c2fdsA_ not modelled 51.9 8 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:orotidine-monophosphate-decarboxylase; PDBTitle: crystal structure of plasmodium berghei orotidine 5'-2 monophosphate decarboxylase (ortholog of plasmodium3 falciparum pf10_0225) 75 c2jfqA_ not modelled 51.5 24 PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of staphylococcus aureus glutamate2 racemase in complex with d-glutamate 76 c3noeA_ not modelled 51.4 14 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from pseudomonas2 aeruginosa 77 c2jfoB_ not modelled 50.9 27 PDB header:isomerase Chain: B: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of enterococcus faecalis glutamate2 racemase in complex with d- and l-glutamate 78 c1vs1B_ not modelled 49.8 24 PDB header:transferase Chain: B: PDB Molecule:3-deoxy-7-phosphoheptulonate synthase; PDBTitle: crystal structure of 3-deoxy-d-arabino-heptulosonate-7-2 phosphate synthase (dahp synthase) from aeropyrum pernix3 in complex with mn2+ and pep 79 c3ng3A_ not modelled 49.6 19 PDB header:lyase Chain: A: PDB Molecule:deoxyribose-phosphate aldolase; PDBTitle: crystal structure of deoxyribose phosphate aldolase from mycobacterium2 avium 104 in a schiff base with an unknown aldehyde 80 d1j93a_ not modelled 49.4 15 Fold:TIM beta/alpha-barrel Superfamily:UROD/MetE-like Family:Uroporphyrinogen decarboxylase, UROD 81 c2ohoA_ not modelled 49.2 24 PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: structural basis for glutamate racemase inhibitor 82 c3nwrA_ not modelled 48.8 19 PDB header:lyase Chain: A: PDB Molecule:a rubisco-like protein; PDBTitle: crystal structure of a rubisco-like protein from burkholderia fungorum 83 c3navB_ not modelled 48.7 18 PDB header:lyase Chain: B: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961 84 c3e96B_ not modelled 48.7 16 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 bacillus clausii 85 c2jfnA_ not modelled 48.4 20 PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of escherichia coli glutamate racemase2 in complex with l-glutamate and activator udp-murnac-ala 86 c3n2xB_ not modelled 47.1 12 PDB header:lyase Chain: B: PDB Molecule:uncharacterized protein yage; PDBTitle: crystal structure of yage, a prophage protein belonging to the2 dihydrodipicolinic acid synthase family from e. coli k12 in complex3 with pyruvate 87 d1ajza_ not modelled 46.2 17 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 88 c1gthD_ not modelled 44.8 22 PDB header:oxidoreductase Chain: D: PDB Molecule:dihydropyrimidine dehydrogenase; PDBTitle: dihydropyrimidine dehydrogenase (dpd) from pig, ternary2 complex with nadph and 5-iodouracil 89 d1o5ka_ not modelled 44.8 16 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 90 d1vzwa1 not modelled 44.1 17 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Histidine biosynthesis enzymes 91 d2a0ma1 not modelled 44.0 24 Fold:Arginase/deacetylase Superfamily:Arginase/deacetylase Family:Arginase-like amidino hydrolases 92 c1b74A_ not modelled 44.0 19 PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: glutamate racemase from aquifex pyrophilus 93 c3eb2A_ not modelled 43.8 21 PDB header:lyase Chain: A: PDB Molecule:putative dihydrodipicolinate synthetase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 rhodopseudomonas palustris at 2.0a resolution 94 c3up8B_ not modelled 42.2 12 PDB header:oxidoreductase Chain: B: PDB Molecule:putative 2,5-diketo-d-gluconic acid reductase b; PDBTitle: crystal structure of a putative 2,5-diketo-d-gluconic acid reductase b 95 c1zcoA_ not modelled 41.7 18 PDB header:lyase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphoheptonate aldolase; PDBTitle: crystal structure of pyrococcus furiosus 3-deoxy-d-arabino-2 heptulosonate 7-phosphate synthase 96 c3ff4A_ not modelled 41.4 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein chu_1412 97 d2icya2 not modelled 40.3 24 Fold:Nucleotide-diphospho-sugar transferases Superfamily:Nucleotide-diphospho-sugar transferases Family:UDP-glucose pyrophosphorylase 98 c3daqB_ not modelled 40.0 17 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from methicillin-2 resistant staphylococcus aureus 99 d1dvja_ not modelled 39.8 12 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase 100 c2q4jB_ not modelled 39.3 23 PDB header:transferase Chain: B: PDB Molecule:probable utp-glucose-1-phosphate uridylyltransferase 2; PDBTitle: ensemble refinement of the protein crystal structure of gene product2 from arabidopsis thaliana at3g03250, a putative udp-glucose3 pyrophosphorylase 101 c3tdmD_ not modelled 39.1 25 PDB header:de novo protein Chain: D: PDB Molecule:computationally designed two-fold symmetric tim-barrel PDBTitle: computationally designed tim-barrel protein, halfflr 102 c2ejaB_ not modelled 38.9 12 PDB header:lyase Chain: B: PDB Molecule:uroporphyrinogen decarboxylase; PDBTitle: crystal structure of uroporphyrinogen decarboxylase from2 aquifex aeolicus 103 c3l0gD_ not modelled 38.6 20 PDB header:transferase Chain: D: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of nicotinate-nucleotide pyrophosphorylase from2 ehrlichia chaffeensis at 2.05a resolution 104 d1km4a_ not modelled 38.2 13 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase 105 d1vbga1 not modelled 38.1 12 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate phosphate dikinase, C-terminal domain 106 d1qo2a_ not modelled 37.9 13 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Histidine biosynthesis enzymes 107 d1fw8a_ not modelled 37.8 21 Fold:Phosphoglycerate kinase Superfamily:Phosphoglycerate kinase Family:Phosphoglycerate kinase 108 c2ehhE_ not modelled 37.7 14 PDB header:lyase Chain: E: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 aquifex aeolicus 109 d1ayia_ not modelled 37.7 14 Fold:Acyl carrier protein-like Superfamily:Colicin E immunity proteins Family:Colicin E immunity proteins 110 d1h5ya_ not modelled 37.6 13 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Histidine biosynthesis enzymes 111 c3qfeB_ not modelled 37.4 13 PDB header:lyase Chain: B: PDB Molecule:putative dihydrodipicolinate synthase family protein; PDBTitle: crystal structures of a putative dihydrodipicolinate synthase family2 protein from coccidioides immitis 112 c3fokH_ not modelled 37.3 14 PDB header:structural genomics, unknown function Chain: H: PDB Molecule:uncharacterized protein cgl0159; PDBTitle: crystal structure of cgl0159 from corynebacterium2 glutamicum (brevibacterium flavum). northeast structural3 genomics target cgr115 113 d1xxxa1 not modelled 37.0 16 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 114 c2yxgD_ not modelled 36.5 14 PDB header:lyase Chain: D: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihyrodipicolinate synthase (dapa) 115 c1qapA_ not modelled 36.5 20 PDB header:glycosyltransferase Chain: A: PDB Molecule:quinolinic acid phosphoribosyltransferase; PDBTitle: quinolinic acid phosphoribosyltransferase with bound2 quinolinic acid 116 c1jpkA_ not modelled 36.5 16 PDB header:lyase Chain: A: PDB Molecule:uroporphyrinogen decarboxylase; PDBTitle: gly156asp mutant of human urod, human uroporphyrinogen iii2 decarboxylase 117 d1twda_ not modelled 36.3 18 Fold:TIM beta/alpha-barrel Superfamily:CutC-like Family:CutC-like 118 d1xkya1 not modelled 35.2 12 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 119 d2af4c1 not modelled 34.9 16 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Phosphotransacetylase 120 c2jfzB_ not modelled 34.3 24 PDB header:isomerase Chain: B: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of helicobacter pylori glutamate racemase2 in complex with d-glutamate and an inhibitor

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0