Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP76205
DateThu Jan 5 12:20:31 GMT 2012
Unique Job IDaced4d7fdb55803c

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d2ajaa1
Top template information
Fold:alpha-alpha superhelix
Superfamily:Pseudo ankyrin repeat-like
Family:Pseudo ankyrin repeat
Confidence and coverage
Confidence:100.0% Coverage: 34%
214 residues ( 34% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSQNDIIIRTHYKSPHRLHIDSDIPTPSSEPINQFARQLITLLDTSDLSSMLSYCVTQEF
Secondary structure 
SS confidence 
Disorder  ??????
?
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  TANCRKISQNCYSTALFTINFATSPIHTENILITLHYKKEIISLLLETTPIKANHLRSIL
Secondary structure 
SS confidence 
Disorder 
???????
???????
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  DYIEQEQLTAEDRNHCMKLSKXSIEKKTIHPTVNLNGSACFLQSPSDAIFCRHLSLQYAL
Secondary structure 
SS confidence 
Disorder 
??
??????????????????????
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  DSLRNGKGKVNLIKHYSSVESIQQHVPLVRDAEFRALLRHPPAGSRVIASKDFGFALDIF
Secondary structure 
SS confidence 
Disorder 
???
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  FCRMMANNVSHMSAILYIDNHTLSVRLRIKQSVYGQLNYVVSVYDPNDTNVAVRDTHRTA
Secondary structure 
SS confidence 
Disorder 
????
?
??
?
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  RGFLSLDKFISSGPDAQTWADRYVRNCAIAILPLLPVGVPGAIFAGIASRMPFAPIHPSA
Secondary structure 
SS confidence 
Disorder 
??
?
?
?
????
???????????
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  MLLIMATGQSQQLITLFKQLPILPEKEIIEIITAQNSVGTPALFLAMMNGHTDNVKIFMQ
Secondary structure 
SS confidence 
Disorder 
?
?
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  EIQSLVDNHIIHEDNLVKLLQTKSANETPGLYISMLYGFDEIIDIFLNALTTPIAQELLN
Secondary structure 
SS confidence 
Disorder 
????????
?
????
Disorder confidence 
 
   .........490.........500.........510.........520.........530.........540
Sequence  KKLVMSILAMKIHDGEPGLYAAMENNHPLCVTRFLSKINGIAFKYKLSKANIMDLLKGAT
Secondary structure 
SS confidence 
Disorder 
?
??????
??
?
Disorder confidence 
 
   .........550.........560.........570.........580.........590.........600
Sequence  AQGTPALYIAMSKGNEDVVLSYISTLGAFAKKHSFSQHQLFTLLAAKNHDNMSAVHIAIH
Secondary structure 
SS confidence 
Disorder  ?
??
Disorder confidence 
 
   .........610.........620.........630..
Sequence  HKHYKTVETYYAAINAISQSLSFSADEIKTYL
Secondary structure 
SS confidence 
Disorder 
?
??????
??
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2aja chain A domain 1

3D model

Region: 369 - 611
Aligned: 214
Modelled: 210
Confidence: 100.0%
Identity: 16%
Fold: alpha-alpha superhelix
Superfamily: Pseudo ankyrin repeat-like
Family: Pseudo ankyrin repeat

Phyre2

PDB 1n11 chain A

3D model

Region: 400 - 612
Aligned: 168
Modelled: 168
Confidence: 100.0%
Identity: 35%
Fold: beta-hairpin-alpha-hairpin repeat
Superfamily: Ankyrin repeat
Family: Ankyrin repeat

Phyre2

PDB 1n11 chain A

3D model

Region: 400 - 612
Aligned: 168
Modelled: 168
Confidence: 100.0%
Identity: 35%
PDB header:structural protein
Chain: A: PDB Molecule:ankyrin;
PDBTitle: d34 region of human ankyrin-r and linker

Phyre2

PDB 2aja chain A

3D model

Region: 370 - 611
Aligned: 201
Modelled: 197
Confidence: 100.0%
Identity: 20%
PDB header:protein binding
Chain: A: PDB Molecule:ankyrin repeat family protein;
PDBTitle: x-ray structure of an ankyrin repeat family protein q5zsv02 from legionella pneumophila. northeast structural genomics3 consortium target lgr21.

Phyre2

PDB 3kea chain B

3D model

Region: 392 - 623
Aligned: 169
Modelled: 168
Confidence: 100.0%
Identity: 19%
PDB header:viral protein
Chain: B: PDB Molecule:k1l;
PDBTitle: structure function studies of vaccinia virus host-range protein k12 reveal a novel ankyrin repeat interaction surface for k1s function

Phyre2

PDB 3ljn chain A

3D model

Region: 396 - 620
Aligned: 193
Modelled: 194
Confidence: 100.0%
Identity: 16%
PDB header:unknown function
Chain: A: PDB Molecule:hypothetical protein;
PDBTitle: ankyrin repeat protein from leishmania major

Phyre2

PDB 2fo1 chain E

3D model

Region: 396 - 611
Aligned: 171
Modelled: 170
Confidence: 100.0%
Identity: 25%
PDB header:gene regulation/signalling protein/dna
Chain: E: PDB Molecule:lin-12 protein;
PDBTitle: crystal structure of the csl-notch-mastermind ternary2 complex bound to dna

Phyre2

PDB 1s70 chain B

3D model

Region: 396 - 618
Aligned: 174
Modelled: 178
Confidence: 100.0%
Identity: 16%
Fold: beta-hairpin-alpha-hairpin repeat
Superfamily: Ankyrin repeat
Family: Ankyrin repeat

Phyre2

PDB 2fo1 chain E domain 1

3D model

Region: 400 - 611
Aligned: 167
Modelled: 167
Confidence: 100.0%
Identity: 25%
Fold: beta-hairpin-alpha-hairpin repeat
Superfamily: Ankyrin repeat
Family: Ankyrin repeat

Phyre2

PDB 2xai chain D

3D model

Region: 400 - 632
Aligned: 173
Modelled: 188
Confidence: 100.0%
Identity: 16%
PDB header:transcription
Chain: D: PDB Molecule:ankyrin repeat and socs box protein 9;
PDBTitle: crystal structure of ankyrin repeat and socs box-containing2 protein 9 (asb9) in complex with elonginb and elonginc

Phyre2

PDB 1wdy chain A

3D model

Region: 398 - 618
Aligned: 192
Modelled: 192
Confidence: 99.9%
Identity: 21%
Fold: beta-hairpin-alpha-hairpin repeat
Superfamily: Ankyrin repeat
Family: Ankyrin repeat

Phyre2

PDB 2f37 chain B

3D model

Region: 395 - 612
Aligned: 201
Modelled: 203
Confidence: 99.9%
Identity: 13%
PDB header:membrane protein
Chain: B: PDB Molecule:transient receptor potential cation channel
PDBTitle: crystal structure of the ankyrin repeat domain of human2 trpv2

Phyre2

PDB 1uoh chain A

3D model

Region: 397 - 611
Aligned: 169
Modelled: 170
Confidence: 99.9%
Identity: 15%
Fold: beta-hairpin-alpha-hairpin repeat
Superfamily: Ankyrin repeat
Family: Ankyrin repeat

Phyre2

PDB 3jxi chain A

3D model

Region: 359 - 615
Aligned: 236
Modelled: 242
Confidence: 99.9%
Identity: 14%
PDB header:membrane protein
Chain: A: PDB Molecule:vanilloid receptor-related osmotically activated channel
PDBTitle: crystal structure of the chicken trpv4 ankyrin repeat domain

Phyre2

PDB 3eu9 chain B

3D model

Region: 396 - 611
Aligned: 186
Modelled: 186
Confidence: 99.9%
Identity: 15%
PDB header:protein binding, methyl-lysine-binding p
Chain: B: PDB Molecule:huntingtin-interacting protein 14;
PDBTitle: the ankyrin repeat domain of huntingtin interacting protein 14

Phyre2

PDB 2vge chain A

3D model

Region: 394 - 611
Aligned: 174
Modelled: 174
Confidence: 99.9%
Identity: 15%
PDB header:transcription
Chain: A: PDB Molecule:rela-associated inhibitor;
PDBTitle: crystal structure of the c-terminal region of human iaspp

Phyre2

PDB 1k1a chain A

3D model

Region: 397 - 608
Aligned: 167
Modelled: 167
Confidence: 99.9%
Identity: 26%
Fold: beta-hairpin-alpha-hairpin repeat
Superfamily: Ankyrin repeat
Family: Ankyrin repeat

Phyre2

PDB 2f8x chain K

3D model

Region: 401 - 612
Aligned: 162
Modelled: 162
Confidence: 99.9%
Identity: 19%
PDB header:transcription/dna
Chain: K: PDB Molecule:neurogenic locus notch homolog protein 1;
PDBTitle: crystal structure of activated notch, csl and maml on hes-12 promoter dna sequence

Phyre2

PDB 3b7b chain B

3D model

Region: 401 - 616
Aligned: 171
Modelled: 171
Confidence: 99.9%
Identity: 18%
PDB header:transferase
Chain: B: PDB Molecule:euchromatic histone-lysine n-methyltransferase 1;
PDBTitle: euhmt1 (glp) ankyrin repeat domain (structure 1)

Phyre2

PDB 3d9h chain A

3D model

Region: 394 - 612
Aligned: 187
Modelled: 189
Confidence: 99.9%
Identity: 15%
PDB header:structural protein, protein binding
Chain: A: PDB Molecule:cdna flj77766, highly similar to homo sapiens
PDBTitle: crystal structure of the splice variant of human asb92 (hasb9-2), an ankyrin repeat protein

Phyre2
1
d2ajaa1
2
d1n11a_
3
c1n11A_
4
c2ajaA_
5
c3keaB_
6
c3ljnA_
7
c2fo1E_
8
d1s70b_
9
d2fo1e1
10
c2xaiD_
11
d1wdya_
12
c2f37B_
13
d1uoha_
14
c3jxiA_
15
c3eu9B_
16
c2vgeA_
17
d1k1aa_
18
c2f8xK_
19
c3b7bB_
20
c3d9hA_
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
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81
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99



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d2ajaa1
100.0 16 Fold:alpha-alpha superhelix
Superfamily:Pseudo ankyrin repeat-like
Family:Pseudo ankyrin repeat
2d1n11a_
100.0 35 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
3c1n11A_
100.0 35 PDB header:structural protein
Chain: A: PDB Molecule:ankyrin;
PDBTitle: d34 region of human ankyrin-r and linker
4c2ajaA_
100.0 20 PDB header:protein binding
Chain: A: PDB Molecule:ankyrin repeat family protein;
PDBTitle: x-ray structure of an ankyrin repeat family protein q5zsv02 from legionella pneumophila. northeast structural genomics3 consortium target lgr21.
5c3keaB_
100.0 19 PDB header:viral protein
Chain: B: PDB Molecule:k1l;
PDBTitle: structure function studies of vaccinia virus host-range protein k12 reveal a novel ankyrin repeat interaction surface for k1s function
6c3ljnA_
100.0 16 PDB header:unknown function
Chain: A: PDB Molecule:hypothetical protein;
PDBTitle: ankyrin repeat protein from leishmania major
7c2fo1E_
100.0 25 PDB header:gene regulation/signalling protein/dna
Chain: E: PDB Molecule:lin-12 protein;
PDBTitle: crystal structure of the csl-notch-mastermind ternary2 complex bound to dna
8d1s70b_
100.0 16 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
9d2fo1e1
100.0 25 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
10c2xaiD_
100.0 16 PDB header:transcription
Chain: D: PDB Molecule:ankyrin repeat and socs box protein 9;
PDBTitle: crystal structure of ankyrin repeat and socs box-containing2 protein 9 (asb9) in complex with elonginb and elonginc
11d1wdya_
99.9 21 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
12c2f37B_
99.9 13 PDB header:membrane protein
Chain: B: PDB Molecule:transient receptor potential cation channel
PDBTitle: crystal structure of the ankyrin repeat domain of human2 trpv2
13d1uoha_
99.9 15 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
14c3jxiA_
99.9 14 PDB header:membrane protein
Chain: A: PDB Molecule:vanilloid receptor-related osmotically activated channel
PDBTitle: crystal structure of the chicken trpv4 ankyrin repeat domain
15c3eu9B_
99.9 15 PDB header:protein binding, methyl-lysine-binding p
Chain: B: PDB Molecule:huntingtin-interacting protein 14;
PDBTitle: the ankyrin repeat domain of huntingtin interacting protein 14
16c2vgeA_
99.9 15 PDB header:transcription
Chain: A: PDB Molecule:rela-associated inhibitor;
PDBTitle: crystal structure of the c-terminal region of human iaspp
17d1k1aa_
99.9 26 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
18c2f8xK_
99.9 19 PDB header:transcription/dna
Chain: K: PDB Molecule:neurogenic locus notch homolog protein 1;
PDBTitle: crystal structure of activated notch, csl and maml on hes-12 promoter dna sequence
19c3b7bB_
99.9 18 PDB header:transferase
Chain: B: PDB Molecule:euchromatic histone-lysine n-methyltransferase 1;
PDBTitle: euhmt1 (glp) ankyrin repeat domain (structure 1)
20c3d9hA_
99.9 15 PDB header:structural protein, protein binding
Chain: A: PDB Molecule:cdna flj77766, highly similar to homo sapiens
PDBTitle: crystal structure of the splice variant of human asb92 (hasb9-2), an ankyrin repeat protein
21d1sw6a_
not modelled 99.9 16 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
22c1sw6A_
not modelled 99.9 16 PDB header:transcription regulation
Chain: A: PDB Molecule:regulatory protein swi6;
PDBTitle: s. cerevisiae swi6 ankyrin-repeat fragment
23c1ycsB_
not modelled 99.9 17 PDB header:complex (anti-oncogene/ankyrin repeats)
Chain: B: PDB Molecule:53bp2;
PDBTitle: p53-53bp2 complex
24c3ui2A_
not modelled 99.9 15 PDB header:transport protein
Chain: A: PDB Molecule:signal recognition particle 43 kda protein, chloroplastic;
PDBTitle: crystal structure of the cpsrp54 tail bound to cpsrp43
25d1iknd_
not modelled 99.9 16 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
26c2nyjA_
not modelled 99.9 11 PDB header:transport protein
Chain: A: PDB Molecule:transient receptor potential cation channel
PDBTitle: crystal structure of the ankyrin repeat domain of trpv1
27d1oy3d_
not modelled 99.9 15 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
28c1oy3D_
not modelled 99.9 15 PDB header:dna binding protein
Chain: D: PDB Molecule:transcription factor inhibitor i-kappa-b-beta;
PDBTitle: crystal structure of an ikbbeta/nf-kb p65 homodimer complex
29c3ehrB_
not modelled 99.9 22 PDB header:signaling protein
Chain: B: PDB Molecule:osteoclast-stimulating factor 1;
PDBTitle: crystal structure of human osteoclast stimulating factor
30c3t8kB_
not modelled 99.9 13 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: the crystal structure of a functionally unknown protein lebu_0176 from2 leptotrichia buccalis c-1013-b
31d1ot8a_
not modelled 99.9 19 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
32d1ixva_
not modelled 99.9 16 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
33d1dcqa1
not modelled 99.9 19 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
34c3jueA_
not modelled 99.9 15 PDB header:protein transport/endocytosis
Chain: A: PDB Molecule:arfgap with coiled-coil, ank repeat and ph domain-
PDBTitle: crystal structure of arfgap and ank repeat domain of acap1
35c2rfaA_
not modelled 99.9 20 PDB header:membrane protein
Chain: A: PDB Molecule:transient receptor potential cation channel subfamily v
PDBTitle: crystal structure of the mouse trpv6 ankyrin repeat domain
36c3deoA_
not modelled 99.9 13 PDB header:protein transport, membrane protein
Chain: A: PDB Molecule:signal recognition particle 43 kda protein;
PDBTitle: structural basis for specific substrate recognition by the2 chloroplast signal recognition particle protein cpsrp43
37c3hraA_
not modelled 99.9 20 PDB header:structural protein
Chain: A: PDB Molecule:ankyrin repeat family protein;
PDBTitle: crystal structure of ef0377 an ankyrin repeat protein
38c2rfmB_
not modelled 99.9 15 PDB header:protein binding
Chain: B: PDB Molecule:putative ankyrin repeat protein tv1425;
PDBTitle: structure of a thermophilic ankyrin repeat protein
39c2b0oF_
not modelled 99.8 16 PDB header:metal binding protein
Chain: F: PDB Molecule:uplc1;
PDBTitle: crystal structure of uplc1 gap domain
40c1dcqA_
not modelled 99.8 16 PDB header:metal binding protein
Chain: A: PDB Molecule:pyk2-associated protein beta;
PDBTitle: crystal structure of the arf-gap domain and ankyrin repeats2 of papbeta.
41c3twtD_
not modelled 99.8 19 PDB header:signaling protein/peptide
Chain: D: PDB Molecule:tankyrase-2;
PDBTitle: crystal structure of arc4 from human tankyrase 2 in complex with2 peptide from human mcl1 (chimeric peptide)
42c2kbxA_
not modelled 99.8 15 PDB header:cell adhesion
Chain: A: PDB Molecule:integrin-linked protein kinase;
PDBTitle: solution structure of ilk-pinch complex
43c3lvrE_
not modelled 99.8 16 PDB header:protein transport
Chain: E: PDB Molecule:arf-gap with sh3 domain, ank repeat and ph domain-
PDBTitle: the crystal structure of asap3 in complex with arf6 in transition2 state soaked with calcium
44d1ycsb1
not modelled 99.8 16 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
45d2a5ea_
not modelled 99.8 15 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
46c3c5rB_
not modelled 99.8 20 PDB header:protein binding
Chain: B: PDB Molecule:brca1-associated ring domain protein 1;
PDBTitle: crystal structure of the bard1 ankyrin repeat domain and its2 functional consequences
47c2zgdA_
not modelled 99.8 20 PDB header:de novo protein
Chain: A: PDB Molecule:3 repeat synthetic ankyrin;
PDBTitle: asn-hydroxylation stabilises the ankyrin repeat domain fold
48d1awcb_
not modelled 99.8 20 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
49c1ympB_
not modelled 99.8 14 PDB header:transcription
Chain: B: PDB Molecule:notch 1 protein;
PDBTitle: the crystal structure of a partial mouse notch-1 ankyrin2 domain: repeats 4 through 7 preserve an ankyrin fold
50c1ympA_
not modelled 99.8 14 PDB header:transcription
Chain: A: PDB Molecule:notch 1 protein;
PDBTitle: the crystal structure of a partial mouse notch-1 ankyrin2 domain: repeats 4 through 7 preserve an ankyrin fold
51c2jabC_
not modelled 99.8 20 PDB header:de novo protein
Chain: C: PDB Molecule:h10-2-g3;
PDBTitle: a designed ankyrin repeat protein evolved to picomolar2 affinity to her2
52d1bi7b_
not modelled 99.8 19 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
53d1ihba_
not modelled 99.7 18 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
54d1myoa_
not modelled 99.7 15 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
55d1bd8a_
not modelled 99.7 13 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
56d1blxb_
not modelled 99.7 17 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
57c2v5qC_
not modelled 99.7 20 PDB header:transferase
Chain: C: PDB Molecule:design ankyrin repeat protein;
PDBTitle: crystal structure of wild-type plk-1 kinase domain in2 complex with a selective darpin
58c2xenA_
not modelled 99.7 24 PDB header:de novo protein
Chain: A: PDB Molecule:ni1c mut4;
PDBTitle: structural determinants for improved thermal stability of2 designed ankyrin repeat proteins with a redesigned c-3 capping module.
59c2l6bA_
not modelled 99.6 20 PDB header:de novo protein
Chain: A: PDB Molecule:nr1c;
PDBTitle: nrc consensus ankyrin repeat protein solution structure
60c1n0qB_
not modelled 99.6 25 PDB header:structural protein
Chain: B: PDB Molecule:3 ankyrin repeats;
PDBTitle: 3ank: a designed ankyrin repeat protein with three identical consensus2 repeats
61c1n0rA_
not modelled 99.5 21 PDB header:structural protein
Chain: A: PDB Molecule:4 ankyrin repeats;
PDBTitle: 4ank: a designed ankyrin repeat protein with four identical2 consensus repeats
62c2xumS_
not modelled 63.6 22 PDB header:oxidoreductase/peptide
Chain: S: PDB Molecule:asp-substrate peptide 2;
PDBTitle: factor inhibiting hif (fih) q239h mutant in complex with zn(ii), nog2 and asp-substrate peptide (20-mer)
63c3zrhA_
not modelled 49.4 15 PDB header:hydrolase
Chain: A: PDB Molecule:ubiquitin thioesterase zranb1;
PDBTitle: crystal structure of the lys29, lys33-linkage-specific trabid otu2 deubiquitinase domain reveals an ankyrin-repeat ubiquitin binding3 domain (ankubd)
64d1d1da1
not modelled 41.0 35 Fold:Acyl carrier protein-like
Superfamily:Retrovirus capsid dimerization domain-like
Family:Retrovirus capsid protein C-terminal domain
65d2qamc2
not modelled 39.2 57 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:Cold shock DNA-binding domain-like
66c1rl2A_
not modelled 35.7 33 PDB header:ribosomal protein
Chain: A: PDB Molecule:protein (ribosomal protein l2);
PDBTitle: ribosomal protein l2 rna-binding domain from bacillus2 stearothermophilus
67d1rl2a2
not modelled 34.5 57 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:Cold shock DNA-binding domain-like
68d1ukfa_
not modelled 31.3 26 Fold:Cysteine proteinases
Superfamily:Cysteine proteinases
Family:Avirulence protein Avrpph3
69c2y0iS_
not modelled 28.1 8 PDB header:oxidoreductase/peptide
Chain: S: PDB Molecule:tankyrase-2;
PDBTitle: factor inhibiting hif-1 alpha in complex with tankyrase-2 (tnks2)2 fragment peptide (21-mer)
70d1nepa_
not modelled 27.2 13 Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:ML domain
71c2zkrn_
not modelled 26.9 13 PDB header:ribosomal protein/rna
Chain: N: PDB Molecule:rna expansion segment es27;
PDBTitle: structure of a mammalian ribosomal 60s subunit within an2 80s complex obtained by docking homology models of the rna3 and proteins into an 8.7 a cryo-em map
72c3cixA_
not modelled 26.6 17 PDB header:adomet binding protein
Chain: A: PDB Molecule:fefe-hydrogenase maturase;
PDBTitle: x-ray structure of the [fefe]-hydrogenase maturase hyde from2 thermotoga maritima in complex with thiocyanate
73d1vqoa2
not modelled 26.5 25 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:Cold shock DNA-binding domain-like
74c2ftcB_
not modelled 25.2 43 PDB header:ribosome
Chain: B: PDB Molecule:mitochondrial ribosomal protein l2;
PDBTitle: structural model for the large subunit of the mammalian mitochondrial2 ribosome
75d2zjra2
not modelled 24.6 57 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:Cold shock DNA-binding domain-like
76c3go5A_
not modelled 22.5 15 PDB header:gene regulation
Chain: A: PDB Molecule:multidomain protein with s1 rna-binding domains;
PDBTitle: crystal structure of a multidomain protein with nucleic acid binding2 domains (sp_0946) from streptococcus pneumoniae tigr4 at 1.40 a3 resolution
77d1hnga1
not modelled 19.8 38 Fold:Immunoglobulin-like beta-sandwich
Superfamily:Immunoglobulin
Family:V set domains (antibody variable domain-like)
78c1af7A_
not modelled 17.9 29 PDB header:methyltransferase
Chain: A: PDB Molecule:chemotaxis receptor methyltransferase cher;
PDBTitle: cher from salmonella typhimurium
79d2j01d2
not modelled 15.2 57 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:Cold shock DNA-binding domain-like
80d1bvua1
not modelled 14.9 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
81c1kqsA_
not modelled 14.4 25 PDB header:ribosome
Chain: A: PDB Molecule:ribosomal protein l2;
PDBTitle: the haloarcula marismortui 50s complexed with a2 pretranslocational intermediate in protein synthesis
82d7reqb1
not modelled 13.2 11 Fold:TIM beta/alpha-barrel
Superfamily:Cobalamin (vitamin B12)-dependent enzymes
Family:Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain
83d2fd5a1
not modelled 12.2 18 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Homeodomain-like
Family:Tetracyclin repressor-like, N-terminal domain
84d1wo8a1
not modelled 12.1 26 Fold:Methylglyoxal synthase-like
Superfamily:Methylglyoxal synthase-like
Family:Methylglyoxal synthase, MgsA
85d2gsta2
not modelled 12.0 16 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Glutathione S-transferase (GST), N-terminal domain
86d2c4ja2
not modelled 11.9 11 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Glutathione S-transferase (GST), N-terminal domain
87c2k0mA_
not modelled 11.9 11 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: solution nmr structure of the uncharacterized protein from2 rhodospirillum rubrum gene locus rru_a0810. northeast3 structural genomics target rrr43
88c2zkra_
not modelled 11.2 25 PDB header:ribosomal protein/rna
Chain: A: PDB Molecule:rna expansion segment es3;
PDBTitle: structure of a mammalian ribosomal 60s subunit within an2 80s complex obtained by docking homology models of the rna3 and proteins into an 8.7 a cryo-em map
89d2vy4a1
not modelled 11.1 40 Fold:beta-beta-alpha zinc fingers
Superfamily:beta-beta-alpha zinc fingers
Family:CHHC finger
90c2b66D_
not modelled 11.0 57 PDB header:ribosome
Chain: D: PDB Molecule:50s ribosomal protein l2;
PDBTitle: 50s ribosomal subunit from a crystal structure of release factor rf1,2 trnas and mrna bound to the ribosome. this file contains the 50s3 subunit from a crystal structure of release factor rf1, trnas and4 mrna bound to the ribosome and is described in remark 400
91c3rrrB_
not modelled 9.4 38 PDB header:viral protein
Chain: B: PDB Molecule:fusion glycoprotein f0;
PDBTitle: structure of the rsv f protein in the post-fusion conformation
92d1czda1
not modelled 9.3 31 Fold:DNA clamp
Superfamily:DNA clamp
Family:DNA polymerase processivity factor
93c1d0rA_
not modelled 9.1 50 PDB header:hormone/growth factor
Chain: A: PDB Molecule:glucagon-like peptide-1-(7-36)-amide;
PDBTitle: solution structure of glucagon-like peptide-1-(7-36)-amide2 in trifluoroethanol/water
94c1n7qA_
not modelled 8.9 16 PDB header:lyase
Chain: A: PDB Molecule:hyaluronidase;
PDBTitle: streptococcus pneumoniae hyaluronate lyase w291a/w292a double mutant2 complex with hyaluronan hexasacchride
95c3ac0B_
not modelled 8.2 17 PDB header:hydrolase
Chain: B: PDB Molecule:beta-glucosidase i;
PDBTitle: crystal structure of beta-glucosidase from kluyveromyces marxianus in2 complex with glucose
96d1fhea2
not modelled 8.2 5 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Glutathione S-transferase (GST), N-terminal domain
97d1eg3a1
not modelled 8.1 48 Fold:EF Hand-like
Superfamily:EF-hand
Family:EF-hand modules in multidomain proteins
98c3rkiB_
not modelled 8.1 38 PDB header:viral protein
Chain: B: PDB Molecule:fusion glycoprotein f0;
PDBTitle: structural basis for immunization with post-fusion rsv f to elicit2 high neutralizing antibody titers
99d1v5ma_
not modelled 7.9 25 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Pleckstrin-homology domain (PH domain)

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0