Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	D	F	S	I	M	V	Y	A	V	I	A	L	V	G	V	A	I	G	W	L	F	A	S	Y	Q	H	A	Q	Q	K	A	E	Q	L	A	E	R	E	E	M	V	A	E	L	S	A	A	K	Q	Q	I	T	Q	S	E	H	W	R	A
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		E	C	E	L	L	N	N	E	V	R	S	L	Q	S	I	N	T	S	L	E	A	D	L	R	E	V	T	T	R	M	E	A	A	Q	Q	H	A	D	D	K	I	R	Q	M	I	N	S	E	Q	R	L	S	E	Q	F	E	N	L	A	N
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	I	F	E	H	S	N	R	R	V	D	E	Q	N	R	Q	S	L	N	S	L	L	S	P	L	R	E	Q	L	D	G	F	R	R	Q	V	Q	D	S	F	G	K	E	A	Q	E	R	H	T	L	T	H	E	I	R	N	L	Q	Q	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		N	A	Q	M	A	Q	E	A	I	N	L	T	R	A	L	K	G	D	N	K	T	Q	G	N	W	G	E	V	V	L	T	R	V	L	E	A	S	G	L	R	E	G	Y	E	Y	E	T	Q	V	S	I	E	N	D	A	R	S	R	M	Q
Secondary structure
SS confidence
Disorder																?	?	?	?	?	?	?	?																			?	?	?									?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		P	D	V	I	V	R	L	P	Q	G	K	D	V	V	I	D	A	K	M	T	L	V	A	Y	E	R	Y	F	N	A	E	D	D	Y	T	R	E	S	A	L	Q	E	H	I	A	S	V	R	N	H	I	R	L	L	G	R	K	D	Y	Q
Secondary structure
SS confidence
Disorder																															?																										?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		Q	L	P	G	L	R	T	L	D	Y	V	L	M	F	I	P	V	E	P	A	F	L	L	A	L	D	R	Q	P	E	L	I	T	E	A	L	K	N	N	I	M	L	V	S	P	T	T	L	L	V	A	L	R	T	I	A	N	L	W	R
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		Y	E	H	Q	S	R	N	A	Q	Q	I	A	D	R	A	S	K	L	Y	D	K	M	R	L	F	I	D	D	M	S	A	I	G	Q	S	L	D	K	A	Q	D	N	Y	R	Q	A	M	K	K	L	S	S	G	R	G	N	V	L	A	Q
Secondary structure
SS confidence
Disorder																																																						?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.
Sequence		A	E	A	F	R	G	L	G	V	E	I	K	R	E	I	N	P	D	L	A	E	Q	A	V	S	Q	D	E	E	Y	R	L	R	S	V	P	E	Q	P	N	D	E	A	Y	Q	R	D	D	E	Y	N	Q	Q	S	R
Secondary structure
SS confidence
Disorder							?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3oja chain B Region: 331 - 472 Aligned: 142 Modelled: 142 Confidence: 97.4% Identity: 13% PDB header:protein binding Chain: B: PDB Molecule:anopheles plasmodium-responsive leucine-rich repeat protein PDBTitle: crystal structure of lrim1/apl1c complex Phyre2 PDB 1bf5 chain A Region: 310 - 474 Aligned: 165 Modelled: 165 Confidence: 96.9% Identity: 7% PDB header:gene regulation/dna Chain: A: PDB Molecule:signal transducer and activator of transcription PDBTitle: tyrosine phosphorylated stat-1/dna complex Phyre2 PDB 1c1g chain A Region: 153 - 433 Aligned: 281 Modelled: 281 Confidence: 96.9% Identity: 8% PDB header:contractile protein Chain: A: PDB Molecule:tropomyosin; PDBTitle: crystal structure of tropomyosin at 7 angstroms resolution2 in the spermine-induced crystal form Phyre2 PDB 1cii chain A Region: 24 - 412 Aligned: 389 Modelled: 389 Confidence: 96.8% Identity: 7% PDB header:transmembrane protein Chain: A: PDB Molecule:colicin ia; PDBTitle: colicin ia Phyre2 PDB 1deq chain F Region: 364 - 473 Aligned: 110 Modelled: 110 Confidence: 96.3% Identity: 7% PDB header: PDB COMPND: Phyre2 PDB 1bg1 chain A Region: 296 - 467 Aligned: 172 Modelled: 172 Confidence: 96.2% Identity: 6% PDB header:transcription/dna Chain: A: PDB Molecule:protein (transcription factor stat3b); PDBTitle: transcription factor stat3b/dna complex Phyre2 PDB 3cwg chain A Region: 303 - 474 Aligned: 163 Modelled: 172 Confidence: 95.7% Identity: 7% PDB header:transcription Chain: A: PDB Molecule:signal transducer and activator of transcription PDBTitle: unphosphorylated mouse stat3 core fragment Phyre2 PDB 1yvl chain B Region: 233 - 474 Aligned: 242 Modelled: 242 Confidence: 95.4% Identity: 7% PDB header:signaling protein Chain: B: PDB Molecule:signal transducer and activator of transcription PDBTitle: structure of unphosphorylated stat1 Phyre2 PDB 2efr chain B Region: 320 - 475 Aligned: 152 Modelled: 156 Confidence: 95.4% Identity: 9% PDB header:contractile protein Chain: B: PDB Molecule:general control protein gcn4 and tropomyosin 1 alpha chain; PDBTitle: crystal structure of the c-terminal tropomyosin fragment with n- and2 c-terminal extensions of the leucine zipper at 1.8 angstroms3 resolution Phyre2 PDB 3o0z chain D Region: 282 - 434 Aligned: 153 Modelled: 153 Confidence: 94.5% Identity: 11% PDB header:transferase Chain: D: PDB Molecule:rho-associated protein kinase 1; PDBTitle: crystal structure of a coiled-coil domain from human rock i Phyre2 PDB 1ei3 chain E Region: 361 - 475 Aligned: 115 Modelled: 115 Confidence: 94.3% Identity: 10% PDB header: PDB COMPND: Phyre2 PDB 3ghg chain K Region: 359 - 470 Aligned: 112 Modelled: 112 Confidence: 93.7% Identity: 12% PDB header:blood clotting Chain: K: PDB Molecule:fibrinogen beta chain; PDBTitle: crystal structure of human fibrinogen Phyre2 PDB 2d3e chain D Region: 311 - 437 Aligned: 127 Modelled: 127 Confidence: 92.9% Identity: 9% PDB header:contractile protein Chain: D: PDB Molecule:general control protein gcn4 and tropomyosin 1 PDBTitle: crystal structure of the c-terminal fragment of rabbit2 skeletal alpha-tropomyosin Phyre2 PDB 3na7 chain A Region: 275 - 451 Aligned: 177 Modelled: 177 Confidence: 92.6% Identity: 8% PDB header:gene regulation, chaperone Chain: A: PDB Molecule:hp0958; PDBTitle: 2.2 angstrom structure of the hp0958 protein from helicobacter pylori2 ccug 17874 Phyre2 PDB 2v71 chain A Region: 325 - 475 Aligned: 151 Modelled: 151 Confidence: 92.5% Identity: 9% PDB header:nuclear protein Chain: A: PDB Molecule:nuclear distribution protein nude-like 1; PDBTitle: coiled-coil region of nudel Phyre2 PDB 1jch chain C Region: 318 - 475 Aligned: 158 Modelled: 158 Confidence: 92.4% Identity: 3% PDB header:ribosome inhibitor, hydrolase Chain: C: PDB Molecule:colicin e3; PDBTitle: crystal structure of colicin e3 in complex with its immunity protein Phyre2 PDB 2v66 chain C Region: 365 - 468 Aligned: 104 Modelled: 104 Confidence: 92.2% Identity: 4% PDB header:structural protein Chain: C: PDB Molecule:nuclear distribution protein nude-like 1; PDBTitle: crystal structure of the coiled-coil domain of ndel1 (a.a.2 58 to 169)c Phyre2 PDB 4a55 chain B Region: 347 - 475 Aligned: 129 Modelled: 129 Confidence: 92.0% Identity: 7% PDB header:transferase Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit alpha; PDBTitle: crystal structure of p110alpha in complex with ish2 of p85alpha and2 the inhibitor pik-108 Phyre2 PDB 2fxm chain B Region: 306 - 417 Aligned: 112 Modelled: 112 Confidence: 91.2% Identity: 7% PDB header:contractile protein Chain: B: PDB Molecule:myosin heavy chain, cardiac muscle beta isoform; PDBTitle: structure of the human beta-myosin s2 fragment Phyre2 PDB 2gl2 chain B Region: 334 - 436 Aligned: 103 Modelled: 103 Confidence: 90.7% Identity: 15% PDB header:cell adhesion Chain: B: PDB Molecule:adhesion a; PDBTitle: crystal structure of the tetra muntant (t66g,r67g,f68g,2 y69g) of bacterial adhesin fada Phyre2 PDB 3hnw chain B Region: 8 - 83 Aligned: 76 Modelled: 73 Confidence: 85.5% Identity: 14% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a basic coiled-coil protein of unknown function2 from eubacterium eligens atcc 27750 Phyre2 1 c3ojaB_ 2 c1bf5A_ 3 c1c1gA_ 4 c1ciiA_ 5 c1deqF_ 6 c1bg1A_ 7 c3cwgA_ 8 c1yvlB_ 9 c2efrB_ 10 c3o0zD_ 11 c1ei3E_ 12 c3ghgK_ 13 c2d3eD_ 14 c3na7A_ 15 c2v71A_ 16 c1jchC_ 17 c2v66C_ 18 c4a55B_ 19 c2fxmB_ 20 c2gl2B_ 21 22 23 24 25 26 27 c3hnwB_ 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3ojaB_ 97.4 13 PDB header:protein binding Chain: B: PDB Molecule:anopheles plasmodium-responsive leucine-rich repeat protein PDBTitle: crystal structure of lrim1/apl1c complex 2 c1bf5A_ 96.9 7 PDB header:gene regulation/dna Chain: A: PDB Molecule:signal transducer and activator of transcription PDBTitle: tyrosine phosphorylated stat-1/dna complex 3 c1c1gA_ 96.9 8 PDB header:contractile protein Chain: A: PDB Molecule:tropomyosin; PDBTitle: crystal structure of tropomyosin at 7 angstroms resolution2 in the spermine-induced crystal form 4 c1ciiA_ 96.8 7 PDB header:transmembrane protein Chain: A: PDB Molecule:colicin ia; PDBTitle: colicin ia 5 c1deqF_ 96.3 7 PDB header: PDB COMPND: 6 c1bg1A_ 96.2 6 PDB header:transcription/dna Chain: A: PDB Molecule:protein (transcription factor stat3b); PDBTitle: transcription factor stat3b/dna complex 7 c3cwgA_ 95.7 7 PDB header:transcription Chain: A: PDB Molecule:signal transducer and activator of transcription PDBTitle: unphosphorylated mouse stat3 core fragment 8 c1yvlB_ 95.4 7 PDB header:signaling protein Chain: B: PDB Molecule:signal transducer and activator of transcription PDBTitle: structure of unphosphorylated stat1 9 c2efrB_ 95.4 9 PDB header:contractile protein Chain: B: PDB Molecule:general control protein gcn4 and tropomyosin 1 alpha chain; PDBTitle: crystal structure of the c-terminal tropomyosin fragment with n- and2 c-terminal extensions of the leucine zipper at 1.8 angstroms3 resolution 10 c3o0zD_ 94.5 11 PDB header:transferase Chain: D: PDB Molecule:rho-associated protein kinase 1; PDBTitle: crystal structure of a coiled-coil domain from human rock i 11 c1ei3E_ 94.3 10 PDB header: PDB COMPND: 12 c3ghgK_ 93.7 12 PDB header:blood clotting Chain: K: PDB Molecule:fibrinogen beta chain; PDBTitle: crystal structure of human fibrinogen 13 c2d3eD_ 92.9 9 PDB header:contractile protein Chain: D: PDB Molecule:general control protein gcn4 and tropomyosin 1 PDBTitle: crystal structure of the c-terminal fragment of rabbit2 skeletal alpha-tropomyosin 14 c3na7A_ 92.6 8 PDB header:gene regulation, chaperone Chain: A: PDB Molecule:hp0958; PDBTitle: 2.2 angstrom structure of the hp0958 protein from helicobacter pylori2 ccug 17874 15 c2v71A_ 92.5 9 PDB header:nuclear protein Chain: A: PDB Molecule:nuclear distribution protein nude-like 1; PDBTitle: coiled-coil region of nudel 16 c1jchC_ 92.4 3 PDB header:ribosome inhibitor, hydrolase Chain: C: PDB Molecule:colicin e3; PDBTitle: crystal structure of colicin e3 in complex with its immunity protein 17 c2v66C_ 92.2 4 PDB header:structural protein Chain: C: PDB Molecule:nuclear distribution protein nude-like 1; PDBTitle: crystal structure of the coiled-coil domain of ndel1 (a.a.2 58 to 169)c 18 c4a55B_ 92.0 7 PDB header:transferase Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit alpha; PDBTitle: crystal structure of p110alpha in complex with ish2 of p85alpha and2 the inhibitor pik-108 19 c2fxmB_ 91.2 7 PDB header:contractile protein Chain: B: PDB Molecule:myosin heavy chain, cardiac muscle beta isoform; PDBTitle: structure of the human beta-myosin s2 fragment 20 c2gl2B_ 90.7 15 PDB header:cell adhesion Chain: B: PDB Molecule:adhesion a; PDBTitle: crystal structure of the tetra muntant (t66g,r67g,f68g,2 y69g) of bacterial adhesin fada 21 c1deqO_ not modelled 90.5 11 PDB header: PDB COMPND: 22 c1ei3C_ not modelled 89.2 6 PDB header: PDB COMPND: 23 c3u59C_ not modelled 89.0 17 PDB header:contractile protein Chain: C: PDB Molecule:tropomyosin beta chain; PDBTitle: n-terminal 98-aa fragment of smooth muscle tropomyosin beta 24 c1deqD_ not modelled 87.4 11 PDB header: PDB COMPND: 25 c3ol1A_ not modelled 86.7 6 PDB header:structural protein Chain: A: PDB Molecule:vimentin; PDBTitle: crystal structure of vimentin (fragment 144-251) from homo sapiens,2 northeast structural genomics consortium target hr4796b 26 c2b9cA_ not modelled 86.2 11 PDB header:contractile protein Chain: A: PDB Molecule:striated-muscle alpha tropomyosin; PDBTitle: structure of tropomyosin's mid-region: bending and binding2 sites for actin 27 c3hnwB_ 85.5 14 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a basic coiled-coil protein of unknown function2 from eubacterium eligens atcc 27750 28 c3hizB_ not modelled 77.6 6 PDB header:transferase/oncoprotein Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha 29 c2rd0B_ not modelled 72.3 8 PDB header:transferase/oncoprotein Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit alpha; PDBTitle: structure of a human p110alpha/p85alpha complex 30 c2i1jA_ not modelled 70.9 11 PDB header:cell adhesion, membrane protein Chain: A: PDB Molecule:moesin; PDBTitle: moesin from spodoptera frugiperda at 2.1 angstroms resolution 31 c2v1yB_ not modelled 62.0 9 PDB header:transferase Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit alpha; PDBTitle: structure of a phosphoinositide 3-kinase alpha adaptor-2 binding domain (abd) in a complex with the ish2 domain3 from p85 alpha 32 c3ojaA_ not modelled 61.6 7 PDB header:protein binding Chain: A: PDB Molecule:leucine-rich immune molecule 1; PDBTitle: crystal structure of lrim1/apl1c complex 33 c1gk4A_ not modelled 54.1 10 PDB header:vimentin Chain: A: PDB Molecule:vimentin; PDBTitle: human vimentin coil 2b fragment (cys2) 34 c2no2A_ not modelled 51.9 8 PDB header:cell adhesion Chain: A: PDB Molecule:huntingtin-interacting protein 1; PDBTitle: crystal structure of the dllrkn-containing coiled-coil2 domain of huntingtin-interacting protein 1 35 d2pila_ not modelled 49.8 13 Fold:Pili subunits Superfamily:Pili subunits Family:Pilin 36 c3dtpA_ not modelled 48.5 7 PDB header:contractile protein Chain: A: PDB Molecule:myosin 2 heavy chain chimera of smooth and PDBTitle: tarantula heavy meromyosin obtained by flexible docking to2 tarantula muscle thick filament cryo-em 3d-map 37 c3ipkA_ not modelled 47.3 8 PDB header:cell adhesion Chain: A: PDB Molecule:agi/ii; PDBTitle: crystal structure of a3vp1 of agi/ii of streptococcus mutans 38 c1hciB_ not modelled 45.2 12 PDB header:triple-helix coiled coil Chain: B: PDB Molecule:alpha-actinin 2; PDBTitle: crystal structure of the rod domain of alpha-actinin 39 c2wpqA_ not modelled 41.8 11 PDB header:membrane protein Chain: A: PDB Molecule:trimeric autotransporter adhesin fragment; PDBTitle: salmonella enterica sada 479-519 fused to gcn4 adaptors (2 sadak3, in-register fusion) 40 c3sokB_ not modelled 38.8 20 PDB header:cell adhesion Chain: B: PDB Molecule:fimbrial protein; PDBTitle: dichelobacter nodosus pilin fima 41 c2voyB_ not modelled 38.4 16 PDB header:hydrolase Chain: B: PDB Molecule:sarcoplasmic/endoplasmic reticulum calcium PDBTitle: cryoem model of copa, the copper transporting atpase from2 archaeoglobus fulgidus 42 c1y4cA_ not modelled 36.8 15 PDB header:de novo protein Chain: A: PDB Molecule:maltose binding protein fused with designed PDBTitle: designed helical protein fusion mbp 43 c1sjjB_ not modelled 32.9 8 PDB header:contractile protein Chain: B: PDB Molecule:actinin; PDBTitle: cryo-em structure of chicken gizzard smooth muscle alpha-2 actinin 44 c1wt6B_ not modelled 32.6 21 PDB header:transferase Chain: B: PDB Molecule:myotonin-protein kinase; PDBTitle: coiled-coil domain of dmpk 45 d1oqwa_ not modelled 32.5 18 Fold:Pili subunits Superfamily:Pili subunits Family:Pilin 46 c2e7sM_ not modelled 32.2 6 PDB header:endocytosis/exocytosis Chain: M: PDB Molecule:rab guanine nucleotide exchange factor sec2; PDBTitle: crystal structure of the yeast sec2p gef domain 47 c2jeeA_ not modelled 31.5 6 PDB header:cell cycle Chain: A: PDB Molecule:yiiu; PDBTitle: xray structure of e. coli yiiu 48 d2ap3a1 not modelled 31.4 10 Fold:Four-helical up-and-down bundle Superfamily:MW0975(SA0943)-like Family:MW0975(SA0943)-like 49 c2y3aB_ not modelled 28.3 5 PDB header:transferase Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta; PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941 50 c2dq3A_ not modelled 26.5 14 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: crystal structure of aq_298 51 c3u1aC_ not modelled 23.4 14 PDB header:contractile protein Chain: C: PDB Molecule:smooth muscle tropomyosin alpha; PDBTitle: n-terminal 81-aa fragment of smooth muscle tropomyosin alpha 52 c3q0xA_ not modelled 22.4 18 PDB header:structural protein Chain: A: PDB Molecule:centriole protein; PDBTitle: n-terminal coiled-coil dimer domain of c. reinhardtii sas-6 homolog2 bld12p 53 c3mraA_ not modelled 21.1 16 PDB header:membrane protein Chain: A: PDB Molecule:nicotinic acetylcholine receptor; PDBTitle: m3 transmembrane segment of alpha-subunit of nicotinic2 acetylcholine receptor from torpedo californica, nmr, 153 structures 54 c3ajwA_ not modelled 19.1 4 PDB header:protein transport Chain: A: PDB Molecule:flagellar flij protein; PDBTitle: structure of flij, a soluble component of flagellar type iii export2 apparatus 55 c1m1jA_ not modelled 18.4 7 PDB header:blood clotting Chain: A: PDB Molecule:fibrinogen alpha subunit; PDBTitle: crystal structure of native chicken fibrinogen with two different2 bound ligands 56 c2oevA_ not modelled 18.3 9 PDB header:protein transport Chain: A: PDB Molecule:programmed cell death 6-interacting protein; PDBTitle: crystal structure of alix/aip1 57 c2qa7B_ not modelled 16.7 5 PDB header:actin binding Chain: B: PDB Molecule:huntingtin-interacting protein 1; PDBTitle: crystal structure of huntingtin-interacting protein 12 (hip1) coiled-coil domain with a basic surface suitable3 for hip-protein interactor (hippi) 58 d1gl4a1 not modelled 16.6 50 Fold:GFP-like Superfamily:GFP-like Family:Domain G2 of nidogen-1 59 c1h4uA_ not modelled 15.6 50 PDB header:extracellular matrix protein Chain: A: PDB Molecule:nidogen-1; PDBTitle: domain g2 of mouse nidogen-1 60 d1jb0m_ not modelled 15.4 32 Fold:Single transmembrane helix Superfamily:Subunit XII of photosystem I reaction centre, PsaM Family:Subunit XII of photosystem I reaction centre, PsaM 61 c1jb0M_ not modelled 15.4 32 PDB header:photosynthesis Chain: M: PDB Molecule:photosystem 1 reaction centre subunit xii; PDBTitle: crystal structure of photosystem i: a photosynthetic reaction center2 and core antenna system from cyanobacteria 62 d2axti1 not modelled 15.3 11 Fold:Single transmembrane helix Superfamily:Photosystem II reaction center protein I, PsbI Family:PsbI-like 63 c3tnfB_ not modelled 14.8 9 PDB header:protein transport Chain: B: PDB Molecule:lida; PDBTitle: lida from legionella in complex with active rab8a 64 c2jo1A_ not modelled 13.7 13 PDB header:hydrolase regulator Chain: A: PDB Molecule:phospholemman; PDBTitle: structure of the na,k-atpase regulatory protein fxyd1 in2 micelles 65 c1x8yA_ not modelled 13.5 13 PDB header:structural protein Chain: A: PDB Molecule:lamin a/c; PDBTitle: human lamin coil 2b 66 c3a7pB_ not modelled 13.1 12 PDB header:protein transport Chain: B: PDB Molecule:autophagy protein 16; PDBTitle: the crystal structure of saccharomyces cerevisiae atg16 67 c3cvfA_ not modelled 12.4 9 PDB header:signaling protein Chain: A: PDB Molecule:homer protein homolog 3; PDBTitle: crystal structure of the carboxy terminus of homer3 68 d1seta1 not modelled 12.2 17 Fold:Long alpha-hairpin Superfamily:tRNA-binding arm Family:Seryl-tRNA synthetase (SerRS) 69 c2jp3A_ not modelled 11.7 13 PDB header:transcription Chain: A: PDB Molecule:fxyd domain-containing ion transport regulator 4; PDBTitle: solution structure of the human fxyd4 (chif) protein in sds2 micelles 70 c3mk7B_ not modelled 11.6 17 PDB header:oxidoreductase Chain: B: PDB Molecule:cytochrome c oxidase, cbb3-type, subunit o; PDBTitle: the structure of cbb3 cytochrome oxidase 71 c2oexB_ not modelled 11.4 9 PDB header:protein transport Chain: B: PDB Molecule:programmed cell death 6-interacting protein; PDBTitle: structure of alix/aip1 v domain 72 c1l8dB_ not modelled 11.4 9 PDB header:replication Chain: B: PDB Molecule:dna double-strand break repair rad50 atpase; PDBTitle: rad50 coiled-coil zn hook 73 c1afoB_ not modelled 11.3 11 PDB header:integral membrane protein Chain: B: PDB Molecule:glycophorin a; PDBTitle: dimeric transmembrane domain of human glycophorin a, nmr,2 20 structures 74 d1q90m_ not modelled 11.3 25 Fold:Single transmembrane helix Superfamily:PetM subunit of the cytochrome b6f complex Family:PetM subunit of the cytochrome b6f complex 75 c2jwaA_ not modelled 10.6 22 PDB header:transferase Chain: A: PDB Molecule:receptor tyrosine-protein kinase erbb-2; PDBTitle: erbb2 transmembrane segment dimer spatial structure 76 c2wvrB_ not modelled 9.9 17 PDB header:replication Chain: B: PDB Molecule:geminin; PDBTitle: human cdt1:geminin complex 77 c2dq0A_ not modelled 9.5 9 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: crystal structure of seryl-trna synthetase from pyrococcus2 horikoshii complexed with a seryl-adenylate analog 78 c3m9bK_ not modelled 9.2 22 PDB header:chaperone Chain: K: PDB Molecule:proteasome-associated atpase; PDBTitle: crystal structure of the amino terminal coiled coil domain and the2 inter domain of the mycobacterium tuberculosis proteasomal atpase mpa 79 c3qh9A_ not modelled 9.0 11 PDB header:structural protein Chain: A: PDB Molecule:liprin-beta-2; PDBTitle: human liprin-beta2 coiled-coil 80 c1debA_ not modelled 8.7 17 PDB header:structural protein Chain: A: PDB Molecule:adenomatous polyposis coli protein; PDBTitle: crystal structure of the n-terminal coiled coil domain from2 apc 81 c2zxeG_ not modelled 8.5 31 PDB header:hydrolase/transport protein Chain: G: PDB Molecule:phospholemman-like protein; PDBTitle: crystal structure of the sodium - potassium pump in the e2.2k+.pi2 state 82 c2xdjF_ not modelled 7.8 11 PDB header:unknown function Chain: F: PDB Molecule:uncharacterized protein ybgf; PDBTitle: crystal structure of the n-terminal domain of e.coli ybgf 83 c3pcqM_ not modelled 7.6 32 PDB header:photosynthesis Chain: M: PDB Molecule:photosystem i reaction center subunit xii; PDBTitle: femtosecond x-ray protein nanocrystallography 84 c2ap7A_ not modelled 7.6 37 PDB header:antibiotic Chain: A: PDB Molecule:bombinin h2; PDBTitle: solution structure of bombinin h2 in dpc micelles 85 c2eqbC_ not modelled 7.3 13 PDB header:endocytosis/exocytosis Chain: C: PDB Molecule:rab guanine nucleotide exchange factor sec2; PDBTitle: crystal structure of the rab gtpase sec4p, the sec2p gef2 domain, and phosphate complex 86 c2hacA_ not modelled 7.2 17 PDB header:membrane protein Chain: A: PDB Molecule:t-cell surface glycoprotein cd3 zeta chain; PDBTitle: structure of zeta-zeta transmembrane dimer 87 c3l9oA_ not modelled 7.1 7 PDB header:hydrolase Chain: A: PDB Molecule:atp-dependent rna helicase dob1; PDBTitle: crystal structure of mtr4, a co-factor of the nuclear exosome 88 c3movB_ not modelled 7.1 10 PDB header:structural protein Chain: B: PDB Molecule:lamin-b1; PDBTitle: crystal structure of human lamin-b1 coil 2 segment 89 c3n4xB_ not modelled 7.0 10 PDB header:replication Chain: B: PDB Molecule:monopolin complex subunit csm1; PDBTitle: structure of csm1 full-length 90 c1fosF_ not modelled 7.0 14 PDB header:transcription/dna Chain: F: PDB Molecule:c-jun proto-oncogene protein; PDBTitle: two human c-fos:c-jun:dna complexes 91 c3n23E_ not modelled 6.6 25 PDB header:hydrolase Chain: E: PDB Molecule:na+/k+ atpase gamma subunit transcript variant a; PDBTitle: crystal structure of the high affinity complex between ouabain and the2 e2p form of the sodium-potassium pump 92 c3lssA_ not modelled 6.5 12 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: trypanosoma brucei seryl-trna synthetase in complex with atp 93 c2zxxA_ not modelled 6.1 17 PDB header:cell cycle/replication Chain: A: PDB Molecule:geminin; PDBTitle: crystal structure of cdt1/geminin complex 94 c3pdsA_ not modelled 6.1 4 PDB header:membrane protein/hydrolase Chain: A: PDB Molecule:fusion protein beta-2 adrenergic receptor/lysozyme; PDBTitle: irreversible agonist-beta2 adrenoceptor complex 95 c1ic2B_ not modelled 5.9 18 PDB header:contractile protein Chain: B: PDB Molecule:tropomyosin alpha chain, skeletal muscle; PDBTitle: deciphering the design of the tropomyosin molecule 96 c1f5nA_ not modelled 5.8 7 PDB header:signaling protein Chain: A: PDB Molecule:interferon-induced guanylate-binding protein 1; PDBTitle: human guanylate binding protein-1 in complex with the gtp2 analogue, gmppnp. 97 d1v54i_ not modelled 5.6 22 Fold:Single transmembrane helix Superfamily:Mitochondrial cytochrome c oxidase subunit VIc Family:Mitochondrial cytochrome c oxidase subunit VIc 98 c1pi8A_ not modelled 5.5 25 PDB header:viral protein Chain: A: PDB Molecule:vpu protein; PDBTitle: structure of the channel-forming trans-membrane domain of2 virus protein "u" (vpu) from hiv-1 99 c2gohA_ not modelled 5.5 25 PDB header:viral protein Chain: A: PDB Molecule:vpu protein; PDBTitle: three-dimensional structure of the trans-membrane domain of2 vpu from hiv-1 in aligned phospholipid bicelles

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0