Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	A	Q	L	T	I	S	N	F	A	I	V	R	E	L	E	I	D	F	H	S	G	M	T	V	I	T	G	E	T	G	A	G	K	S	I	A	I	D	A	L	G	L	C	L	G	G	R	A	E	A	D	M	V	R	T	G	A	A
Secondary structure
SS confidence
Disorder		?	?	?																																																?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	A	D	L	C	A	R	F	S	L	K	D	T	P	A	A	L	R	W	L	E	E	N	Q	L	E	D	G	H	E	C	L	L	R	R	V	I	S	S	D	G	R	S	R	G	F	I	N	G	T	A	V	P	L	S	Q	L	R	E	L
Secondary structure
SS confidence
Disorder													?																																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	Q	L	L	I	Q	I	H	G	Q	H	A	H	Q	L	L	T	K	P	E	H	Q	K	F	L	L	D	G	Y	A	N	E	T	S	L	L	Q	E	M	T	A	R	Y	Q	L	W	H	Q	S	C	R	D	L	A	H	H	Q	Q	L	S
Secondary structure
SS confidence
Disorder																	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Q	E	R	A	A	R	A	E	L	L	Q	Y	Q	L	K	E	L	N	E	F	N	P	Q	P	G	E	F	E	Q	I	D	E	E	Y	K	R	L	A	N	S	G	Q	L	L	T	T	S	Q	N	A	L	A	L	M	A	D	G	E	D	A
Secondary structure
SS confidence
Disorder																					?	?	?	?	?	?																													?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		N	L	Q	S	Q	L	Y	T	A	K	Q	L	V	S	E	L	I	G	M	D	S	K	L	S	G	V	L	D	M	L	E	E	A	T	I	Q	I	A	E	A	S	D	E	L	R	H	Y	C	D	R	L	D	L	D	P	N	R	L	F	E
Secondary structure
SS confidence
Disorder																																																			?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		L	E	Q	R	I	S	K	Q	I	S	L	A	R	K	H	H	V	S	P	E	A	L	P	Q	Y	Y	Q	S	L	L	E	E	Q	Q	Q	L	D	D	Q	A	D	S	Q	E	T	L	A	L	A	V	T	K	H	H	Q	Q	A	L	E	I
Secondary structure
SS confidence
Disorder																?	?	?	?																				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		A	R	A	L	H	Q	Q	R	Q	Q	Y	A	E	E	L	A	Q	L	I	T	D	S	M	H	A	L	S	M	P	H	G	Q	F	T	I	D	V	K	F	D	E	H	H	L	G	A	D	G	A	D	R	I	E	F	R	V	T	T	N	P
Secondary structure
SS confidence
Disorder																												?		?		?										?	?																		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		G	Q	P	M	Q	P	I	A	K	V	A	S	G	G	E	L	S	R	I	A	L	A	I	Q	V	I	T	A	R	K	M	E	T	P	A	L	I	F	D	E	V	D	V	G	I	S	G	P	T	A	A	V	V	G	K	L	L	R	Q	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?					?																	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		G	E	S	T	Q	V	M	C	V	T	H	L	P	Q	V	A	G	C	G	H	Q	H	Y	F	V	S	K	E	T	D	G	A	M	T	E	T	H	M	Q	S	L	N	K	K	A	R	L	Q	E	L	A	R	L	L	G	G	S	E	V	T
Secondary structure
SS confidence
Disorder																															?	?	?	?								?	?														?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.
Sequence		R	N	T	L	A	N	A	K	E	L	L	A	A
Secondary structure
SS confidence
Disorder													?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1w1w chain A Region: 2 - 523 Aligned: 268 Modelled: 270 Confidence: 100.0% Identity: 23% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: ABC transporter ATPase domain-like Phyre2 PDB 2o5v chain A Region: 2 - 493 Aligned: 299 Modelled: 308 Confidence: 100.0% Identity: 29% PDB header:replication/recombination Chain: A: PDB Molecule:dna replication and repair protein recf; PDBTitle: recombination mediator recf Phyre2 PDB 3auy chain B Region: 2 - 510 Aligned: 331 Modelled: 340 Confidence: 100.0% Identity: 22% PDB header:recombination Chain: B: PDB Molecule:dna double-strand break repair rad50 atpase; PDBTitle: crystal structure of rad50 bound to adp Phyre2 PDB 3g5u chain B Region: 13 - 517 Aligned: 201 Modelled: 215 Confidence: 99.9% Identity: 25% PDB header:membrane protein Chain: B: PDB Molecule:multidrug resistance protein 1a; PDBTitle: structure of p-glycoprotein reveals a molecular basis for2 poly-specific drug binding Phyre2 PDB 1yqt chain A Region: 13 - 506 Aligned: 171 Modelled: 173 Confidence: 99.9% Identity: 21% PDB header:hydrolyase/translation Chain: A: PDB Molecule:rnase l inhibitor; PDBTitle: rnase-l inhibitor Phyre2 PDB 1e69 chain A Region: 2 - 516 Aligned: 253 Modelled: 253 Confidence: 99.9% Identity: 25% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: ABC transporter ATPase domain-like Phyre2 PDB 1z47 chain B Region: 4 - 517 Aligned: 202 Modelled: 221 Confidence: 99.9% Identity: 24% PDB header:ligand binding protein Chain: B: PDB Molecule:putative abc-transporter atp-binding protein; PDBTitle: structure of the atpase subunit cysa of the putative2 sulfate atp-binding cassette (abc) transporter from3 alicyclobacillus acidocaldarius Phyre2 PDB 3dhw chain C Region: 5 - 508 Aligned: 201 Modelled: 205 Confidence: 99.9% Identity: 32% PDB header:membrane protein/hydrolase Chain: C: PDB Molecule:methionine import atp-binding protein metn; PDBTitle: crystal structure of methionine importer metni Phyre2 PDB 1xex chain B Region: 365 - 535 Aligned: 157 Modelled: 162 Confidence: 99.9% Identity: 20% PDB header:cell cycle Chain: B: PDB Molecule:smc protein; PDBTitle: structural biochemistry of atp-driven dimerization and dna2 stimulated activation of smc atpases. Phyre2 PDB 3fvq chain B Region: 4 - 517 Aligned: 206 Modelled: 216 Confidence: 99.9% Identity: 19% PDB header:hydrolase Chain: B: PDB Molecule:fe(3+) ions import atp-binding protein fbpc; PDBTitle: crystal structure of the nucleotide binding domain fbpc2 complexed with atp Phyre2 PDB 1oxt chain B Region: 1 - 517 Aligned: 209 Modelled: 218 Confidence: 99.9% Identity: 24% PDB header:transport protein Chain: B: PDB Molecule:abc transporter, atp binding protein; PDBTitle: crystal structure of glcv, the abc-atpase of the glucose abc2 transporter from sulfolobus solfataricus Phyre2 PDB 3qg5 chain A Region: 2 - 320 Aligned: 319 Modelled: 319 Confidence: 99.9% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:rad50; PDBTitle: the mre11:rad50 complex forms an atp dependent molecular clamp in dna2 double-strand break repair Phyre2 PDB 2it1 chain B Region: 4 - 517 Aligned: 202 Modelled: 234 Confidence: 99.9% Identity: 20% PDB header:transport protein Chain: B: PDB Molecule:362aa long hypothetical maltose/maltodextrin PDBTitle: structure of ph0203 protein from pyrococcus horikoshii Phyre2 PDB 1ii8 chain B Region: 337 - 516 Aligned: 168 Modelled: 180 Confidence: 99.8% Identity: 14% PDB header:replication Chain: B: PDB Molecule:rad50 abc-atpase; PDBTitle: crystal structure of the p. furiosus rad50 atpase domain Phyre2 PDB 1jj7 chain A Region: 1 - 508 Aligned: 207 Modelled: 212 Confidence: 99.8% Identity: 34% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: ABC transporter ATPase domain-like Phyre2 PDB 1xex chain A Region: 2 - 150 Aligned: 140 Modelled: 149 Confidence: 99.8% Identity: 26% PDB header:cell cycle Chain: A: PDB Molecule:smc protein; PDBTitle: structural biochemistry of atp-driven dimerization and dna2 stimulated activation of smc atpases. Phyre2 PDB 1ii8 chain A Region: 2 - 184 Aligned: 183 Modelled: 183 Confidence: 99.8% Identity: 15% PDB header:replication Chain: A: PDB Molecule:rad50 abc-atpase; PDBTitle: crystal structure of the p. furiosus rad50 atpase domain Phyre2 PDB 2d3w chain B Region: 5 - 517 Aligned: 214 Modelled: 223 Confidence: 99.8% Identity: 24% PDB header:biosynthetic protein Chain: B: PDB Molecule:probable atp-dependent transporter sufc; PDBTitle: crystal structure of escherichia coli sufc, an atpase2 compenent of the suf iron-sulfur cluster assembly machinery Phyre2 PDB 1f2u chain D Region: 368 - 514 Aligned: 135 Modelled: 147 Confidence: 99.8% Identity: 16% PDB header:replication Chain: D: PDB Molecule:rad50 abc-atpase; PDBTitle: crystal structure of rad50 abc-atpase Phyre2 PDB 3qku chain B Region: 1 - 97 Aligned: 97 Modelled: 97 Confidence: 99.8% Identity: 22% PDB header:replication Chain: B: PDB Molecule:dna double-strand break repair rad50 atpase; PDBTitle: mre11 rad50 binding domain in complex with rad50 and amp-pnp Phyre2 PDB 2yz2 chain B Region: 424 - 553 Aligned: 115 Modelled: 115 Confidence: 99.6% Identity: 20% PDB header:hydrolase Chain: B: PDB Molecule:putative abc transporter atp-binding protein tm_0222; PDBTitle: crystal structure of the abc transporter in the cobalt transport2 system Phyre2 1 d1w1wa_ 2 c2o5vA_ 3 c3auyB_ 4 c3g5uB_ 5 c1yqtA_ 6 d1e69a_ 7 c1z47B_ 8 c3dhwC_ 9 c1xexB_ 10 c3fvqB_ 11 c1oxtB_ 12 c3qg5A_ 13 c2it1B_ 14 c1ii8B_ 15 d1jj7a_ 16 c1xexA_ 17 c1ii8A_ 18 c2d3wB_ 19 c1f2uD_ 20 c3qkuB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 c2yz2B_ 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499