PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2cbzA_

Fold library id	PDB Header	Molecule	Title
c2cbzA_	PDB header: transport	Chain: A: PDB Molecule: multidrug resistance-associated protein 1;	PDBTitle: structure of the human multidrug resistance protein 12 nucleotide binding domain 1

Links to external resources
Added to library: Tue Mar 16 11:59:02 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence N S I T V R N A T F T W A R S D P P T L N G I T F S I P E G A L V A V V G Q V G C G K S S L L S A L L A E M D K V E G H V A I K G S V A Y V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T T S
S
T T
S T T S S T T
S
S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence P Q Q A W I Q N D S L R E N I L F G C Q L E E P Y Y R S V I Q A C A L L P D L E I L P S G D R T E I G E K G V N L S G G Q K Q R V S L A R A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
S T T S
T T T T
T T S T T G G G S S T T S B

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence V Y S N A D I Y L F D D P L S A V D A H V G K H I F E N V I G P K G M L K N K T R I L V T H S M S Y L P Q V D V I I V M S G G K I S E M G S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S T T T T S
T T S T T S T T T T S
S
S T T G G G S S T T

. . . . . . . . . 220 . . . . . . . . . 230

Sequence Y Q E L L A R D G A F A E F L R T Y A S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	N	S	I	T	V	R	N	A	T	F	T	W	A	R	S	D	P	P	T	L	N	G	I	T	F	S	I	P	E	G	A	L	V	A	V	V	G	Q	V	G	C	G	K	S	S	L	L	S	A	L	L	A	E	M	D	K	V	E	G	H	V	A	I	K	G	S	V	A	Y	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												S		T	T	S			S										T	T								S	T	T	S	S									T	T		S											S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	P	Q	Q	A	W	I	Q	N	D	S	L	R	E	N	I	L	F	G	C	Q	L	E	E	P	Y	Y	R	S	V	I	Q	A	C	A	L	L	P	D	L	E	I	L	P	S	G	D	R	T	E	I	G	E	K	G	V	N	L	S	G	G	Q	K	Q	R	V	S	L	A	R	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S	S					S									T	T	S				T	T									T	T						T	T	S	T	T	G	G	G	S			S	T	T	S	B
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	V	Y	S	N	A	D	I	Y	L	F	D	D	P	L	S	A	V	D	A	H	V	G	K	H	I	F	E	N	V	I	G	P	K	G	M	L	K	N	K	T	R	I	L	V	T	H	S	M	S	Y	L	P	Q	V	D	V	I	I	V	M	S	G	G	K	I	S	E	M	G	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						S						S	T	T	T	T	S												T	T	S	T	T	S	T	T	T	T	S							S		S	T	T	G	G	G	S	S							T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230
Sequence	Y	Q	E	L	L	A	R	D	G	A	F	A	E	F	L	R	T	Y	A	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T	S									T