1 c2oq1A_
100.0
28
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase zap-70;PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide
2 c4fl2A_
100.0
27
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase syk;PDBTitle: structural and biophysical characterization of the syk activation2 switch
3 c2ozoA_
100.0
31
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase zap-70;PDBTitle: autoinhibited intact human zap-70
4 c2b3oA_
100.0
35
PDB header: hydrolaseChain: A: PDB Molecule: tyrosine-protein phosphatase, non-receptor typePDBTitle: crystal structure of human tyrosine phosphatase shp-1
5 c2shpA_
100.0
26
PDB header: tyrosine phosphataseChain: A: PDB Molecule: shp-2;PDBTitle: tyrosine phosphatase shp-2
6 c1a81E_
100.0
31
PDB header: complex (transferase/peptide)Chain: E: PDB Molecule: syk kinase;PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam
7 c3ps5A_
100.0
28
PDB header: hydrolase, signaling proteinChain: A: PDB Molecule: tyrosine-protein phosphatase non-receptor type 6;PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1
8 c3gqiB_
100.0
34
PDB header: transferase/transferase inhibitorChain: B: PDB Molecule: phospholipase c-gamma-1;PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates
9 c2y3aB_
100.0
100
PDB header: transferaseChain: B: PDB Molecule: phosphatidylinositol 3-kinase regulatory subunit beta;PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
10 c3hizB_
100.0
77
PDB header: transferase/oncoproteinChain: B: PDB Molecule: phosphatidylinositol 3-kinase regulatory subunitPDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha
11 c1xa6A_
100.0
19
PDB header: signaling proteinChain: A: PDB Molecule: beta2-chimaerin;PDBTitle: crystal structure of the human beta2-chimaerin
12 c2xs6A_
100.0
72
PDB header: transferaseChain: A: PDB Molecule: phosphatidylinositol 3-kinase regulatory subunit beta;PDBTitle: crystal structure of the rhogap domain of human pik3r2
13 c1pbwB_
100.0
33
PDB header: phosphotransferaseChain: B: PDB Molecule: phosphatidylinositol 3-kinase;PDBTitle: structure of bcr-homology (bh) domain
14 c2ee5A_
100.0
19
PDB header: hydrolaseChain: A: PDB Molecule: rho gtpase activating protein 5 variant;PDBTitle: solution structure of the n-teruminus extended rhogap2 domain from human rho gtpase activating protein 5 variant
15 c3qisA_
100.0
22
PDB header: hydrolase/protein bindingChain: A: PDB Molecule: inositol polyphosphate 5-phosphatase ocrl-1;PDBTitle: recognition of the f&h motif by the lowe syndrome protein ocrl
16 d1pbwa_
100.0
35
Fold: GTPase activation domain, GAPSuperfamily: GTPase activation domain, GAPFamily: BCR-homology GTPase activation domain (BH-domain)17 c2ovjA_
100.0
27
PDB header: signaling proteinChain: A: PDB Molecule: rac gtpase-activating protein 1;PDBTitle: the crystal structure of the human rac gtpase activating protein 12 (racgap1) mgcracgap.
18 c2ngrB_
100.0
23
PDB header: hydrolaseChain: B: PDB Molecule: protein (gtpase activating protein (rhg));PDBTitle: transition state complex for gtp hydrolysis by cdc42:2 comparisons of the high resolution structures for cdc423 bound to the active and catalytically compromised forms of4 the cdc42-gap.
19 c3iugA_
100.0
21
PDB header: splicingChain: A: PDB Molecule: rho/cdc42/rac gtpase-activating protein rics;PDBTitle: crystal structure of the rhogap domain of rics
20 d1xa6a1
100.0
20
Fold: GTPase activation domain, GAPSuperfamily: GTPase activation domain, GAPFamily: BCR-homology GTPase activation domain (BH-domain)21 d1tx4a_
not modelled
100.0
23
Fold: GTPase activation domain, GAPSuperfamily: GTPase activation domain, GAPFamily: BCR-homology GTPase activation domain (BH-domain)22 c3byiA_
not modelled
100.0
20
PDB header: signaling proteinChain: A: PDB Molecule: rho gtpase activating protein 15;PDBTitle: crystal structure of human rho gtpase activating protein 15 (arhgap15)
23 c3kuqA_
not modelled
100.0
16
PDB header: hydrolase activatorChain: A: PDB Molecule: rho gtpase-activating protein 7;PDBTitle: crystal structure of the dlc1 rhogap domain
24 c3fk2B_
not modelled
100.0
19
PDB header: signaling protein, hydrolase activatorChain: B: PDB Molecule: glucocorticoid receptor dna-binding factor 1;PDBTitle: crystal structure of the rhogap domain of human2 glucocorticoid receptor dna-binding factor 1
25 c1f7cA_
not modelled
100.0
21
PDB header: signaling proteinChain: A: PDB Molecule: rhogap protein;PDBTitle: crystal structure of the bh domain from graf, the gtpase2 regulator associated with focal adhesion kinase
26 d1f7ca_
not modelled
100.0
21
Fold: GTPase activation domain, GAPSuperfamily: GTPase activation domain, GAPFamily: BCR-homology GTPase activation domain (BH-domain)27 c3msxB_
not modelled
100.0
17
PDB header: protein bindingChain: B: PDB Molecule: rho gtpase-activating protein 20;PDBTitle: crystal structure of rhoa.gdp.mgf3 in complex with gap domain of2 arhgap20
28 c1k9aB_
99.9
35
PDB header: transferaseChain: B: PDB Molecule: carboxyl-terminal src kinase;PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
29 c2fo0A_
not modelled
99.9
32
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase abl1 (1b isoform);PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
30 c2qv2A_
not modelled
99.9
18
PDB header: hydrolaseChain: A: PDB Molecule: inositol polyphosphate 5-phosphatase ocrl-1;PDBTitle: a role of the lowe syndrome protein ocrl in early steps of2 the endocytic pathway
31 c1oplA_
not modelled
99.9
34
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase;PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
32 c1y57A_
not modelled
99.9
53
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase src;PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
33 d1pica_
not modelled
99.9
72
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain34 c1x27F_
not modelled
99.9
53
PDB header: signaling proteinChain: F: PDB Molecule: proto-oncogene tyrosine-protein kinase lck;PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas
35 d1qada_
not modelled
99.9
78
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain36 d2oq1a1
not modelled
99.9
29
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain37 c2h8hA_
not modelled
99.9
53
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase src;PDBTitle: src kinase in complex with a quinazoline inhibitor
38 c2c0iA_
not modelled
99.9
40
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase hck;PDBTitle: src family kinase hck with bound inhibitor a-420983
39 c3eapD_
not modelled
99.9
17
PDB header: hydrolase activatorChain: D: PDB Molecule: rho gtpase-activating protein 11a;PDBTitle: crystal structure of the rhogap domain of arhgap11a
40 c2eo6A_
not modelled
99.9
30
PDB header: signaling proteinChain: A: PDB Molecule: b-cell linker protein;PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk
41 c2dlzA_
not modelled
99.9
27
PDB header: signaling proteinChain: A: PDB Molecule: protein vav-2;PDBTitle: solution structure of the sh2 domain of human protein vav-2
42 c2crhA_
not modelled
99.9
29
PDB header: signaling proteinChain: A: PDB Molecule: vav proto-oncogene;PDBTitle: solution structure of the sh2 domain of human proto-2 oncogene protein vav1
43 d1a81a1
not modelled
99.9
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain44 c3or8A_
not modelled
99.9
25
PDB header: transcriptionChain: A: PDB Molecule: transcription elongation factor spt6;PDBTitle: a tandem sh2 domain in transcription elongation factor spt6
45 d1a81e1
not modelled
99.9
28
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain46 c2dlyA_
not modelled
99.9
38
PDB header: transferaseChain: A: PDB Molecule: fyn-related kinase;PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase
47 c2ablA_
not modelled
99.9
28
PDB header: transferaseChain: A: PDB Molecule: abl tyrosine kinase;PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase
48 d2oq1a2
not modelled
99.9
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain49 c2lctA_
not modelled
99.9
30
PDB header: signaling proteinChain: A: PDB Molecule: proto-oncogene vav;PDBTitle: solution structure of the vav1 sh2 domain complexed with a syk-derived2 doubly phosphorylated peptide
50 c2ge9A_
not modelled
99.9
31
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase btk;PDBTitle: solution structures of the sh2 domain of bruton's tyrosine2 kinase
51 d1a81e2
not modelled
99.9
33
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain52 d1a81a2
not modelled
99.9
33
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain53 c2vifA_
not modelled
99.9
38
PDB header: signaling proteinChain: A: PDB Molecule: suppressor of cytokine signalling 6;PDBTitle: crystal structure of socs6 sh2 domain in complex with a c-kit2 phosphopeptide
54 d2shpa2
not modelled
99.9
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain55 c2gsbA_
not modelled
99.9
24
PDB header: signaling proteinChain: A: PDB Molecule: ras gtpase-activating protein 1;PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1
56 d1fu6a_
not modelled
99.9
85
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain57 c2eobA_
not modelled
99.9
33
PDB header: hydrolaseChain: A: PDB Molecule: 1-phosphatidylinositol-4,5-bisphosphatePDBTitle: solution structure of the second sh2 domain from rat plc2 gamma-2
58 d1csya_
not modelled
99.9
32
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain59 d1opka2
not modelled
99.9
34
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain60 d1lkka_
not modelled
99.9
38
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain61 d1qcfa2
not modelled
99.9
36
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain62 d1jwoa_
not modelled
99.9
33
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain63 c2ysxA_
not modelled
99.9
29
PDB header: signaling proteinChain: A: PDB Molecule: signaling inositol polyphosphate phosphatasePDBTitle: solution structure of the human ship sh2 domain
64 d1nrva_
not modelled
99.9
24
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain65 d1rjaa_
not modelled
99.9
32
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain66 d1k9aa2
not modelled
99.9
33
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain67 c2xp1A_
not modelled
99.9
22
PDB header: transcriptionChain: A: PDB Molecule: spt6;PDBTitle: structure of the tandem sh2 domains from antonospora locustae2 transcription elongation factor spt6
68 d2izva2
not modelled
99.9
20
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain69 c2knoA_
not modelled
99.9
32
PDB header: hydrolaseChain: A: PDB Molecule: tensin-like c1 domain-containing phosphatase;PDBTitle: nmr solution structure of sh2 domain of the human tensin like c12 domain containing phosphatase (tenc1)
70 c2izvA_
not modelled
99.9
20
PDB header: transcriptionChain: A: PDB Molecule: suppressor of cytokine signaling 4;PDBTitle: crystal structure of socs-4 in complex with elongin-b and2 elongin-c at 2.55a resolution
71 c1ka6A_
not modelled
99.9
29
PDB header: immune systemChain: A: PDB Molecule: sh2 domain protein 1a;PDBTitle: sap/sh2d1a bound to peptide n-py
72 d1blja_
not modelled
99.9
33
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain73 c2eo3A_
not modelled
99.9
28
PDB header: signaling proteinChain: A: PDB Molecule: crk-like protein;PDBTitle: solution structure of the sh2 domain from human crk-like2 protein
74 c2lqnA_
not modelled
99.9
27
PDB header: signaling proteinChain: A: PDB Molecule: crk-like protein;PDBTitle: solution structure of crkl
75 c1x6cA_
not modelled
99.9
29
PDB header: signaling proteinChain: A: PDB Molecule: tyrosine-protein phosphatase, non-receptor typePDBTitle: solution structures of the sh2 domain of human protein-2 tyrosine phosphatase shp-1
76 d1fhsa_
not modelled
99.9
34
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain77 d1bkla_
not modelled
99.9
33
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain78 c2hmhA_
not modelled
99.9
27
PDB header: cytokine regulatorChain: A: PDB Molecule: suppressor of cytokine signaling 3;PDBTitle: crystal structure of socs3 in complex with gp130(ptyr757)2 phosphopeptide.
79 d1g83a2
not modelled
99.9
35
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain80 d1ayaa_
not modelled
99.9
28
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain81 d1o48a_
not modelled
99.9
33
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain82 d1luia_
not modelled
99.8
28
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain83 d2qmsa1
not modelled
99.8
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain84 d3c7ia1
not modelled
99.8
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain85 c2augB_
not modelled
99.8
28
PDB header: signaling proteinChain: B: PDB Molecule: growth factor receptor-bound protein 14;PDBTitle: crystal structure of the grb14 sh2 domain
86 d1i3za_
not modelled
99.8
31
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain87 c3nhnA_
not modelled
99.8
31
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase hck;PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region
88 d1f2fa_
not modelled
99.8
33
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain89 c2ekxA_
not modelled
99.8
32
PDB header: signaling proteinChain: A: PDB Molecule: cytoplasmic tyrosine-protein kinase bmx;PDBTitle: solution structure of the human bmx sh2 domain
90 d1d4ta_
not modelled
99.8
29
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain91 d2shpa3
not modelled
99.8
29
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain92 c2hdxB_
not modelled
99.8
21
PDB header: signaling proteinChain: B: PDB Molecule: sh2-b ph domain containing signaling mediator 1PDBTitle: crystal structure of the src homology-2 domain of sh2-b in2 complex with jak2 ptyr813 phosphopeptide
93 d2cs0a1
not modelled
99.8
26
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain94 d2eyva1
not modelled
99.8
33
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain95 c2c9wA_
not modelled
99.8
25
PDB header: transcription regulationChain: A: PDB Molecule: suppressor of cytokine signaling 2;PDBTitle: crystal structure of socs-2 in complex with elongin-b and2 elongin-c at 1.9a resolution
96 c2dm0A_
not modelled
99.8
32
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase txk;PDBTitle: solution structure of the sh2 domain of human tyrosine-2 protein kinase txk
97 d1cwea_
not modelled
99.8
40
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain98 d1r1qa_
not modelled
99.8
33
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain99 c2ci8A_
not modelled
99.8
26
PDB header: translationChain: A: PDB Molecule: cytoplasmic protein nck1;PDBTitle: sh2 domain of human nck1 adaptor protein - uncomplexed
100 c3mazA_
not modelled
99.8
16
PDB header: signaling proteinChain: A: PDB Molecule: signal-transducing adaptor protein 1;PDBTitle: crystal structure of the human brdg1/stap-1 sh2 domain in complex with2 the ntal ptyr136 peptide
101 d1mila_
not modelled
99.8
30
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain102 d2fcia1
not modelled
99.8
31
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain103 c1g83A_
not modelled
99.8
30
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase fyn;PDBTitle: crystal structure of fyn sh3-sh2
104 d1xa6a2
not modelled
99.8
28
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain105 c2kk6A_
not modelled
99.8
30
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase fer;PDBTitle: solution structure of sh2 domain of proto-oncogene tyrosine-2 protein kinase fer from homo sapiens, northeast structural3 genomics consortium (nesg) target hr3461d
106 c2dcrA_
not modelled
99.8
28
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase fes/fps;PDBTitle: fully automated solution structure determination of the fes2 sh2 domain
107 d1jyra_
not modelled
99.8
37
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain108 d2c9wa2
not modelled
99.8
26
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain109 c2el8A_
not modelled
99.8
20
PDB header: signaling proteinChain: A: PDB Molecule: signal-transducing adaptor protein 2;PDBTitle: solution structure of the human stap2 sh2 domain
110 c3gxxB_
not modelled
99.8
25
PDB header: transcriptionChain: B: PDB Molecule: transcription elongation factor spt6;PDBTitle: structure of the sh2 domain of the candida glabrata2 transcription elongation factor spt6, crystal form b
111 c2cr4A_
not modelled
99.7
26
PDB header: signaling proteinChain: A: PDB Molecule: sh3 domain-binding protein 2;PDBTitle: solution structure of the sh2 domain of human sh3bp2 protein
112 c2dx0B_
not modelled
99.7
35
PDB header: hydrolaseChain: B: PDB Molecule: phospholipase c, gamma 2;PDBTitle: crystal structure of the n-terminal sh2 domain of mouse2 phospholipase c-gamma 2
113 c1rqqC_
not modelled
99.7
28
PDB header: transferase/signaling proteinChain: C: PDB Molecule: adaptor protein aps;PDBTitle: crystal structure of the insulin receptor kinase in complex2 with the sh2 domain of aps
114 d1rpya_
not modelled
99.7
20
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain115 c2eyzA_
not modelled
99.7
30
PDB header: signaling proteinChain: A: PDB Molecule: v-crk sarcoma virus ct10 oncogene homologPDBTitle: ct10-regulated kinase isoform ii
116 c3qwxX_
not modelled
99.7
25
PDB header: signaling proteinChain: X: PDB Molecule: cell death abnormality protein 2;PDBTitle: ced-2 1-174
117 c2dvjA_
not modelled
99.7
37
PDB header: signaling proteinChain: A: PDB Molecule: v-crk sarcoma virus ct10 oncogene homolog,PDBTitle: phosphorylated crk-ii
118 c2eyyA_
not modelled
99.7
29
PDB header: signaling proteinChain: A: PDB Molecule: v-crk sarcoma virus ct10 oncogene homologPDBTitle: ct10-regulated kinase isoform i
119 c3qwyA_
not modelled
99.7
26
PDB header: signaling proteinChain: A: PDB Molecule: cell death abnormality protein 2;PDBTitle: ced-2
120 c2v1yB_
not modelled
99.5
74
PDB header: transferaseChain: B: PDB Molecule: phosphatidylinositol 3-kinase regulatory subunit alpha;PDBTitle: structure of a phosphoinositide 3-kinase alpha adaptor-2 binding domain (abd) in a complex with the ish2 domain3 from p85 alpha
