1 c2eo6A_
99.9
32
PDB header: signaling proteinChain: A: PDB Molecule: b-cell linker protein;PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk
2 c2hdxB_
99.9
27
PDB header: signaling proteinChain: B: PDB Molecule: sh2-b ph domain containing signaling mediator 1PDBTitle: crystal structure of the src homology-2 domain of sh2-b in2 complex with jak2 ptyr813 phosphopeptide
3 c2eo3A_
99.9
29
PDB header: signaling proteinChain: A: PDB Molecule: crk-like protein;PDBTitle: solution structure of the sh2 domain from human crk-like2 protein
4 c2gsbA_
99.9
28
PDB header: signaling proteinChain: A: PDB Molecule: ras gtpase-activating protein 1;PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1
5 d1mila_
99.9
33
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain6 c2lqnA_
99.9
25
PDB header: signaling proteinChain: A: PDB Molecule: crk-like protein;PDBTitle: solution structure of crkl
7 c2dcrA_
99.9
32
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase fes/fps;PDBTitle: fully automated solution structure determination of the fes2 sh2 domain
8 c2kk6A_
99.9
33
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase fer;PDBTitle: solution structure of sh2 domain of proto-oncogene tyrosine-2 protein kinase fer from homo sapiens, northeast structural3 genomics consortium (nesg) target hr3461d
9 c2hmhA_
99.9
24
PDB header: cytokine regulatorChain: A: PDB Molecule: suppressor of cytokine signaling 3;PDBTitle: crystal structure of socs3 in complex with gp130(ptyr757)2 phosphopeptide.
10 d1qada_
99.9
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain11 d1fhsa_
99.9
28
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain12 d2shpa2
99.9
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain13 d1pica_
99.9
26
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain14 c2c9wA_
99.8
28
PDB header: transcription regulationChain: A: PDB Molecule: suppressor of cytokine signaling 2;PDBTitle: crystal structure of socs-2 in complex with elongin-b and2 elongin-c at 1.9a resolution
15 c1x6cA_
99.8
28
PDB header: signaling proteinChain: A: PDB Molecule: tyrosine-protein phosphatase, non-receptor typePDBTitle: solution structures of the sh2 domain of human protein-2 tyrosine phosphatase shp-1
16 d3c7ia1
99.8
28
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain17 c2dlzA_
99.8
17
PDB header: signaling proteinChain: A: PDB Molecule: protein vav-2;PDBTitle: solution structure of the sh2 domain of human protein vav-2
18 d1ayaa_
99.8
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain19 c3gqiB_
99.8
21
PDB header: transferase/transferase inhibitorChain: B: PDB Molecule: phospholipase c-gamma-1;PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates
20 c2eobA_
99.8
29
PDB header: hydrolaseChain: A: PDB Molecule: 1-phosphatidylinositol-4,5-bisphosphatePDBTitle: solution structure of the second sh2 domain from rat plc2 gamma-2
21 c3hizB_
not modelled
99.8
29
PDB header: transferase/oncoproteinChain: B: PDB Molecule: phosphatidylinositol 3-kinase regulatory subunitPDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha
22 d1r1qa_
not modelled
99.8
23
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain23 c2knoA_
not modelled
99.8
25
PDB header: hydrolaseChain: A: PDB Molecule: tensin-like c1 domain-containing phosphatase;PDBTitle: nmr solution structure of sh2 domain of the human tensin like c12 domain containing phosphatase (tenc1)
24 c2crhA_
not modelled
99.8
26
PDB header: signaling proteinChain: A: PDB Molecule: vav proto-oncogene;PDBTitle: solution structure of the sh2 domain of human proto-2 oncogene protein vav1
25 c2ci8A_
not modelled
99.8
33
PDB header: translationChain: A: PDB Molecule: cytoplasmic protein nck1;PDBTitle: sh2 domain of human nck1 adaptor protein - uncomplexed
26 d1a81e2
not modelled
99.8
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain27 c2vifA_
not modelled
99.8
35
PDB header: signaling proteinChain: A: PDB Molecule: suppressor of cytokine signalling 6;PDBTitle: crystal structure of socs6 sh2 domain in complex with a c-kit2 phosphopeptide
28 d2shpa3
not modelled
99.8
29
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain29 c2izvA_
not modelled
99.8
19
PDB header: transcriptionChain: A: PDB Molecule: suppressor of cytokine signaling 4;PDBTitle: crystal structure of socs-4 in complex with elongin-b and2 elongin-c at 2.55a resolution
30 c2lctA_
not modelled
99.8
26
PDB header: signaling proteinChain: A: PDB Molecule: proto-oncogene vav;PDBTitle: solution structure of the vav1 sh2 domain complexed with a syk-derived2 doubly phosphorylated peptide
31 d2oq1a1
not modelled
99.8
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain32 c1ka6A_
not modelled
99.8
27
PDB header: immune systemChain: A: PDB Molecule: sh2 domain protein 1a;PDBTitle: sap/sh2d1a bound to peptide n-py
33 d1fu6a_
not modelled
99.8
29
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain34 d1blja_
not modelled
99.8
28
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain35 c2shpA_
not modelled
99.8
26
PDB header: tyrosine phosphataseChain: A: PDB Molecule: shp-2;PDBTitle: tyrosine phosphatase shp-2
36 d1luia_
not modelled
99.8
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain37 d2izva2
not modelled
99.8
17
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain38 c2dlyA_
not modelled
99.8
33
PDB header: transferaseChain: A: PDB Molecule: fyn-related kinase;PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase
39 d2cs0a1
not modelled
99.8
26
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain40 d2fcia1
not modelled
99.8
30
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain41 d1k9aa2
not modelled
99.8
30
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain42 d1lkka_
not modelled
99.8
30
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain43 d1opka2
not modelled
99.8
32
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain44 d1a81a2
not modelled
99.8
26
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain45 c2fo0A_
not modelled
99.8
33
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase abl1 (1b isoform);PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
46 d2eyva1
not modelled
99.8
33
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain47 d1g83a2
not modelled
99.8
29
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain48 d2c9wa2
not modelled
99.8
29
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain49 d1csya_
not modelled
99.8
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain50 c2ablA_
not modelled
99.8
32
PDB header: transferaseChain: A: PDB Molecule: abl tyrosine kinase;PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase
51 c2y3aB_
not modelled
99.8
26
PDB header: transferaseChain: B: PDB Molecule: phosphatidylinositol 3-kinase regulatory subunit beta;PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
52 c2el8A_
not modelled
99.8
19
PDB header: signaling proteinChain: A: PDB Molecule: signal-transducing adaptor protein 2;PDBTitle: solution structure of the human stap2 sh2 domain
53 c2ysxA_
not modelled
99.8
34
PDB header: signaling proteinChain: A: PDB Molecule: signaling inositol polyphosphate phosphatasePDBTitle: solution structure of the human ship sh2 domain
54 d1d4ta_
not modelled
99.8
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain55 d1rjaa_
not modelled
99.8
29
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain56 d1a81e1
not modelled
99.8
23
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain57 d1nrva_
not modelled
99.8
23
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain58 d1a81a1
not modelled
99.8
23
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain59 d1jwoa_
not modelled
99.8
26
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain60 c2ekxA_
not modelled
99.8
31
PDB header: signaling proteinChain: A: PDB Molecule: cytoplasmic tyrosine-protein kinase bmx;PDBTitle: solution structure of the human bmx sh2 domain
61 d2oq1a2
not modelled
99.8
32
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain62 c1k9aB_
not modelled
99.8
27
PDB header: transferaseChain: B: PDB Molecule: carboxyl-terminal src kinase;PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
63 c2ge9A_
not modelled
99.8
33
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase btk;PDBTitle: solution structures of the sh2 domain of bruton's tyrosine2 kinase
64 c2oq1A_
not modelled
99.8
28
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase zap-70;PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide
65 c1x27F_
not modelled
99.8
30
PDB header: signaling proteinChain: F: PDB Molecule: proto-oncogene tyrosine-protein kinase lck;PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas
66 c2augB_
not modelled
99.8
25
PDB header: signaling proteinChain: B: PDB Molecule: growth factor receptor-bound protein 14;PDBTitle: crystal structure of the grb14 sh2 domain
67 d1o48a_
not modelled
99.8
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain68 d1f2fa_
not modelled
99.8
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain69 d1qcfa2
not modelled
99.8
30
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain70 d1bkla_
not modelled
99.8
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain71 d1i3za_
not modelled
99.8
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain72 d1xa6a2
not modelled
99.8
19
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain73 c1y57A_
not modelled
99.8
29
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase src;PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
74 d1jyra_
not modelled
99.7
30
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain75 c2dm0A_
not modelled
99.7
33
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase txk;PDBTitle: solution structure of the sh2 domain of human tyrosine-2 protein kinase txk
76 d1rpya_
not modelled
99.7
26
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain77 c1oplA_
not modelled
99.7
33
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase;PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
78 c3nhnA_
not modelled
99.7
30
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase hck;PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region
79 d1cwea_
not modelled
99.7
31
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain80 d2qmsa1
not modelled
99.7
28
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain81 c1rqqC_
not modelled
99.7
28
PDB header: transferase/signaling proteinChain: C: PDB Molecule: adaptor protein aps;PDBTitle: crystal structure of the insulin receptor kinase in complex2 with the sh2 domain of aps
82 c2h8hA_
not modelled
99.7
28
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase src;PDBTitle: src kinase in complex with a quinazoline inhibitor
83 c2cr4A_
not modelled
99.7
17
PDB header: signaling proteinChain: A: PDB Molecule: sh3 domain-binding protein 2;PDBTitle: solution structure of the sh2 domain of human sh3bp2 protein
84 c2b3oA_
not modelled
99.7
26
PDB header: hydrolaseChain: A: PDB Molecule: tyrosine-protein phosphatase, non-receptor typePDBTitle: crystal structure of human tyrosine phosphatase shp-1
85 c2eyyA_
not modelled
99.7
27
PDB header: signaling proteinChain: A: PDB Molecule: v-crk sarcoma virus ct10 oncogene homologPDBTitle: ct10-regulated kinase isoform i
86 c1a81E_
not modelled
99.7
27
PDB header: complex (transferase/peptide)Chain: E: PDB Molecule: syk kinase;PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam
87 c3gxxB_
not modelled
99.7
19
PDB header: transcriptionChain: B: PDB Molecule: transcription elongation factor spt6;PDBTitle: structure of the sh2 domain of the candida glabrata2 transcription elongation factor spt6, crystal form b
88 c1g83A_
not modelled
99.7
32
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase fyn;PDBTitle: crystal structure of fyn sh3-sh2
89 c2c0iA_
not modelled
99.7
31
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase hck;PDBTitle: src family kinase hck with bound inhibitor a-420983
90 c2dvjA_
not modelled
99.7
30
PDB header: signaling proteinChain: A: PDB Molecule: v-crk sarcoma virus ct10 oncogene homolog,PDBTitle: phosphorylated crk-ii
91 c2eyzA_
not modelled
99.7
30
PDB header: signaling proteinChain: A: PDB Molecule: v-crk sarcoma virus ct10 oncogene homologPDBTitle: ct10-regulated kinase isoform ii
92 c3mazA_
not modelled
99.7
18
PDB header: signaling proteinChain: A: PDB Molecule: signal-transducing adaptor protein 1;PDBTitle: crystal structure of the human brdg1/stap-1 sh2 domain in complex with2 the ntal ptyr136 peptide
93 c4fl2A_
not modelled
99.7
25
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase syk;PDBTitle: structural and biophysical characterization of the syk activation2 switch
94 c3ps5A_
not modelled
99.7
31
PDB header: hydrolase, signaling proteinChain: A: PDB Molecule: tyrosine-protein phosphatase non-receptor type 6;PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1
95 c2ozoA_
not modelled
99.6
27
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase zap-70;PDBTitle: autoinhibited intact human zap-70
96 c3qwxX_
not modelled
99.6
29
PDB header: signaling proteinChain: X: PDB Molecule: cell death abnormality protein 2;PDBTitle: ced-2 1-174
97 c3qwyA_
not modelled
99.5
27
PDB header: signaling proteinChain: A: PDB Molecule: cell death abnormality protein 2;PDBTitle: ced-2
98 c3or8A_
not modelled
99.5
22
PDB header: transcriptionChain: A: PDB Molecule: transcription elongation factor spt6;PDBTitle: a tandem sh2 domain in transcription elongation factor spt6
99 c2dx0B_
not modelled
99.5
31
PDB header: hydrolaseChain: B: PDB Molecule: phospholipase c, gamma 2;PDBTitle: crystal structure of the n-terminal sh2 domain of mouse2 phospholipase c-gamma 2
100 d1uura3
not modelled
99.5
22
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain101 d1bg1a3
not modelled
99.4
19
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain102 c2xp1A_
not modelled
99.4
29
PDB header: transcriptionChain: A: PDB Molecule: spt6;PDBTitle: structure of the tandem sh2 domains from antonospora locustae2 transcription elongation factor spt6
103 d1bf5a3
not modelled
99.3
21
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain104 c1xa6A_
not modelled
99.2
20
PDB header: signaling proteinChain: A: PDB Molecule: beta2-chimaerin;PDBTitle: crystal structure of the human beta2-chimaerin
105 c3cblA_
not modelled
98.9
40
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase fes/fps;PDBTitle: crystal structure of human feline sarcoma viral oncogene homologue (v-2 fes) in complex with staurosporine and a consensus peptide
106 c1yvlB_
not modelled
97.9
23
PDB header: signaling proteinChain: B: PDB Molecule: signal transducer and activator of transcriptionPDBTitle: structure of unphosphorylated stat1
107 c1bf5A_
not modelled
97.7
26
PDB header: gene regulation/dnaChain: A: PDB Molecule: signal transducer and activator of transcriptionPDBTitle: tyrosine phosphorylated stat-1/dna complex
108 c1y1uA_
not modelled
97.6
19
PDB header: signaling proteinChain: A: PDB Molecule: signal transducer and activator of transcription 5a;PDBTitle: structure of unphosphorylated stat5a
109 c1uusA_
not modelled
97.5
24
PDB header: signal transductionChain: A: PDB Molecule: stat protein;PDBTitle: structure of an activated dictyostelium stat in its2 dna-unbound form
110 c1bg1A_
not modelled
97.4
22
PDB header: transcription/dnaChain: A: PDB Molecule: protein (transcription factor stat3b);PDBTitle: transcription factor stat3b/dna complex
111 c2cblA_
not modelled
97.1
20
PDB header: complex (proto-oncogene/peptide)Chain: A: PDB Molecule: proto-oncogene cbl;PDBTitle: n-terminal domain of cbl in complex with its binding site2 on zap-70
112 c3bunB_
not modelled
97.1
20
PDB header: ligase/signaling proteinChain: B: PDB Molecule: e3 ubiquitin-protein ligase cbl;PDBTitle: crystal structure of c-cbl-tkb domain complexed with its2 binding motif in sprouty4
113 c1griA_
not modelled
95.1
25
PDB header: signal transduction adaptorChain: A: PDB Molecule: growth factor bound protein 2;PDBTitle: grb2
114 c3cwgA_
not modelled
94.3
30
PDB header: transcriptionChain: A: PDB Molecule: signal transducer and activator of transcriptionPDBTitle: unphosphorylated mouse stat3 core fragment
115 c1fbvA_
not modelled
87.1
20
PDB header: ligaseChain: A: PDB Molecule: signal transduction protein cbl;PDBTitle: structure of a cbl-ubch7 complex: ring domain function in2 ubiquitin-protein ligases
116 d1h6va3
not modelled
60.5
14
Fold: CO dehydrogenase flavoprotein C-domain-likeSuperfamily: FAD/NAD-linked reductases, dimerisation (C-terminal) domainFamily: FAD/NAD-linked reductases, dimerisation (C-terminal) domain117 d1gska1
not modelled
60.1
17
Fold: Cupredoxin-likeSuperfamily: CupredoxinsFamily: Multidomain cupredoxins118 d1ef7a_
not modelled
59.9
25
Fold: Cysteine proteinasesSuperfamily: Cysteine proteinasesFamily: Papain-like119 d1kv7a1
not modelled
58.6
19
Fold: Cupredoxin-likeSuperfamily: CupredoxinsFamily: Multidomain cupredoxins120 c3u2aA_
not modelled
53.8
44
PDB header: hydrolaseChain: A: PDB Molecule: ggdef family protein;PDBTitle: adaptor dependent degradation of a cell-cycle regulator reveals2 diversity in substrate architectures
