Secondary structure and disorder prediction

1

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10

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20

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30

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40

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50

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60

Sequence

M

K

H

G

I

K

A

L

L

I

T

L

S

L

A

C

A

G

M

S

H

S

A

L

A

A

A

S

V

A

K

P

T

A

V

E

T

K

A

E

A

P

A

A

Q

S

K

A

A

V

P

A

K

A

S

D

E

E

G

T

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

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?

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?

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?

?

?

?

?

?

?

?

?

?

Disorder confidence

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70

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80

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90

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100

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110

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120

Sequence

R

V

S

I

N

N

A

S

A

E

E

L

A

R

A

M

N

G

V

G

L

K

K

A

Q

A

I

V

S

Y

R

E

E

Y

G

P

F

K

T

V

E

D

L

K

Q

V

P

G

M

G

N

S

L

V

E

R

N

L

A

V

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

?

?

?

Disorder confidence

.

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.

Sequence

L

T

L

Secondary structure

SS confidence

Disorder

?

?

?

Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2edu chain A domain 1 Region: 41 - 120 Aligned: 79 Modelled: 80 Confidence: 99.7% Identity: 33% Fold: SAM domain-like Superfamily: RuvA domain 2-like Family: ComEA-like Phyre2 PDB 3bzk chain A domain 1 Region: 62 - 123 Aligned: 61 Modelled: 62 Confidence: 99.7% Identity: 34% Fold: SAM domain-like Superfamily: RuvA domain 2-like Family: Tex HhH-containing domain-like Phyre2 PDB 2duy chain A domain 1 Region: 54 - 122 Aligned: 64 Modelled: 69 Confidence: 99.7% Identity: 42% Fold: SAM domain-like Superfamily: RuvA domain 2-like Family: ComEA-like Phyre2 PDB 1s5l chain U Region: 37 - 123 Aligned: 82 Modelled: 87 Confidence: 99.7% Identity: 20% PDB header:photosynthesis Chain: U: PDB Molecule:photosystem ii 12 kda extrinsic protein; PDBTitle: architecture of the photosynthetic oxygen evolving center Phyre2 PDB 2axt chain U domain 1 Region: 45 - 121 Aligned: 72 Modelled: 77 Confidence: 99.7% Identity: 22% Fold: SAM domain-like Superfamily: PsbU/PolX domain-like Family: PsbU-like Phyre2 PDB 2oce chain A Region: 62 - 123 Aligned: 61 Modelled: 62 Confidence: 99.4% Identity: 34% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein pa5201; PDBTitle: crystal structure of tex family protein pa5201 from2 pseudomonas aeruginosa Phyre2 PDB 3psi chain A Region: 62 - 123 Aligned: 61 Modelled: 62 Confidence: 99.1% Identity: 20% PDB header:transcription Chain: A: PDB Molecule:transcription elongation factor spt6; PDBTitle: crystal structure of the spt6 core domain from saccharomyces2 cerevisiae, form spt6(239-1451) Phyre2 PDB 3psf chain A Region: 62 - 123 Aligned: 61 Modelled: 62 Confidence: 99.0% Identity: 21% PDB header:transcription Chain: A: PDB Molecule:transcription elongation factor spt6; PDBTitle: crystal structure of the spt6 core domain from saccharomyces2 cerevisiae, form spt6(236-1259) Phyre2 PDB 2bgw chain A domain 1 Region: 63 - 122 Aligned: 59 Modelled: 60 Confidence: 98.2% Identity: 19% Fold: SAM domain-like Superfamily: RuvA domain 2-like Family: Hef domain-like Phyre2 PDB 1x2i chain A domain 1 Region: 72 - 122 Aligned: 50 Modelled: 51 Confidence: 97.9% Identity: 20% Fold: SAM domain-like Superfamily: RuvA domain 2-like Family: Hef domain-like Phyre2 PDB 1kft chain A Region: 71 - 122 Aligned: 51 Modelled: 52 Confidence: 97.8% Identity: 29% PDB header:dna binding protein Chain: A: PDB Molecule:excinuclease abc subunit c; PDBTitle: solution structure of the c-terminal domain of uvrc from e-2 coli Phyre2 PDB 1kft chain A Region: 71 - 122 Aligned: 51 Modelled: 52 Confidence: 97.8% Identity: 29% Fold: SAM domain-like Superfamily: RuvA domain 2-like Family: Excinuclease UvrC C-terminal domain Phyre2 PDB 3ci0 chain K domain 2 Region: 60 - 123 Aligned: 63 Modelled: 64 Confidence: 97.7% Identity: 24% Fold: SAM domain-like Superfamily: GspK insert domain-like Family: GspK insert domain-like Phyre2 PDB 3ci0 chain K Region: 57 - 123 Aligned: 66 Modelled: 67 Confidence: 97.5% Identity: 20% PDB header:protein transport Chain: K: PDB Molecule:pseudopilin gspk; PDBTitle: the crystal structure of the gspk-gspi-gspj complex from2 enterotoxigenic escherichia coli type 2 secretion system Phyre2 PDB 2i5h chain A domain 1 Region: 71 - 118 Aligned: 46 Modelled: 48 Confidence: 97.5% Identity: 30% Fold: AF1531-like Superfamily: AF1531-like Family: AF1531-like Phyre2 PDB 2i5h chain A Region: 71 - 118 Aligned: 46 Modelled: 48 Confidence: 97.5% Identity: 30% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein af1531; PDBTitle: crystal structure of af1531 from archaeoglobus fulgidus,2 pfam duf655 Phyre2 PDB 2hnh chain A Region: 72 - 117 Aligned: 45 Modelled: 46 Confidence: 97.4% Identity: 27% PDB header:transferase Chain: A: PDB Molecule:dna polymerase iii alpha subunit; PDBTitle: crystal structure of the catalytic alpha subunit of e. coli2 replicative dna polymerase iii Phyre2 PDB 3f2c chain A Region: 75 - 117 Aligned: 42 Modelled: 43 Confidence: 97.3% Identity: 45% PDB header:transferase/dna Chain: A: PDB Molecule:geobacillus kaustophilus dna polc; PDBTitle: dna polymerase polc from geobacillus kaustophilus complex with dna,2 dgtp and mn Phyre2 PDB 2bcu chain A Region: 67 - 120 Aligned: 52 Modelled: 54 Confidence: 97.2% Identity: 25% PDB header:transferase, lyase/dna Chain: A: PDB Molecule:dna polymerase lambda; PDBTitle: dna polymerase lambda in complex with a dna duplex2 containing an unpaired damp and a t:t mismatch Phyre2 PDB 3e0d chain A Region: 75 - 117 Aligned: 43 Modelled: 43 Confidence: 97.2% Identity: 33% PDB header:transferase/dna Chain: A: PDB Molecule:dna polymerase iii subunit alpha; PDBTitle: insights into the replisome from the crystral structure of2 the ternary complex of the eubacterial dna polymerase iii3 alpha-subunit Phyre2 1 d2edua1 2 d3bzka1 3 d2duya1 4 c1s5lu_ 5 d2axtu1 6 c2oceA_ 7 c3psiA_ 8 c3psfA_ 9 d2bgwa1 10 d1x2ia1 11 c1kftA_ 12 d1kfta_ 13 d3ci0k2 14 c3ci0K_ 15 d2i5ha1 16 c2i5hA_ 17 c2hnhA_ 18 c3f2cA_ 19 c2bcuA_ 20 c3e0dA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d2edua1 99.7 33 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:ComEA-like 2 d3bzka1 99.7 34 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Tex HhH-containing domain-like 3 d2duya1 99.7 42 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:ComEA-like 4 c1s5lu_ 99.7 20 PDB header:photosynthesis Chain: U: PDB Molecule:photosystem ii 12 kda extrinsic protein; PDBTitle: architecture of the photosynthetic oxygen evolving center 5 d2axtu1 99.7 22 Fold:SAM domain-like Superfamily:PsbU/PolX domain-like Family:PsbU-like 6 c2oceA_ 99.4 34 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein pa5201; PDBTitle: crystal structure of tex family protein pa5201 from2 pseudomonas aeruginosa 7 c3psiA_ 99.1 20 PDB header:transcription Chain: A: PDB Molecule:transcription elongation factor spt6; PDBTitle: crystal structure of the spt6 core domain from saccharomyces2 cerevisiae, form spt6(239-1451) 8 c3psfA_ 99.0 21 PDB header:transcription Chain: A: PDB Molecule:transcription elongation factor spt6; PDBTitle: crystal structure of the spt6 core domain from saccharomyces2 cerevisiae, form spt6(236-1259) 9 d2bgwa1 98.2 19 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Hef domain-like 10 d1x2ia1 97.9 20 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Hef domain-like 11 c1kftA_ 97.8 29 PDB header:dna binding protein Chain: A: PDB Molecule:excinuclease abc subunit c; PDBTitle: solution structure of the c-terminal domain of uvrc from e-2 coli 12 d1kfta_ 97.8 29 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Excinuclease UvrC C-terminal domain 13 d3ci0k2 97.7 24 Fold:SAM domain-like Superfamily:GspK insert domain-like Family:GspK insert domain-like 14 c3ci0K_ 97.5 20 PDB header:protein transport Chain: K: PDB Molecule:pseudopilin gspk; PDBTitle: the crystal structure of the gspk-gspi-gspj complex from2 enterotoxigenic escherichia coli type 2 secretion system 15 d2i5ha1 97.5 30 Fold:AF1531-like Superfamily:AF1531-like Family:AF1531-like 16 c2i5hA_ 97.5 30 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein af1531; PDBTitle: crystal structure of af1531 from archaeoglobus fulgidus,2 pfam duf655 17 c2hnhA_ 97.4 27 PDB header:transferase Chain: A: PDB Molecule:dna polymerase iii alpha subunit; PDBTitle: crystal structure of the catalytic alpha subunit of e. coli2 replicative dna polymerase iii 18 c3f2cA_ 97.3 45 PDB header:transferase/dna Chain: A: PDB Molecule:geobacillus kaustophilus dna polc; PDBTitle: dna polymerase polc from geobacillus kaustophilus complex with dna,2 dgtp and mn 19 c2bcuA_ 97.2 25 PDB header:transferase, lyase/dna Chain: A: PDB Molecule:dna polymerase lambda; PDBTitle: dna polymerase lambda in complex with a dna duplex2 containing an unpaired damp and a t:t mismatch 20 c3e0dA_ 97.2 33 PDB header:transferase/dna Chain: A: PDB Molecule:dna polymerase iii subunit alpha; PDBTitle: insights into the replisome from the crystral structure of2 the ternary complex of the eubacterial dna polymerase iii3 alpha-subunit 21 d2i1qa1 not modelled 97.2 20 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:DNA repair protein Rad51, N-terminal domain 22 d1pzna1 not modelled 97.1 17 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:DNA repair protein Rad51, N-terminal domain 23 d1dgsa1 not modelled 97.0 19 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:NAD+-dependent DNA ligase, domain 3 24 c8iczA_ not modelled 96.9 29 PDB header:transferase/dna Chain: A: PDB Molecule:protein (dna polymerase beta (e.c.2.7.7.7)); PDBTitle: dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with2 seven base pairs of dna; soaked in the presence of of datp3 (1 millimolar), mncl2 (5 millimolar), and lithium sulfate4 (75 millimolar) 25 d2a1jb1 not modelled 96.9 25 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Hef domain-like 26 c1ixrA_ not modelled 96.8 30 PDB header:hydrolase Chain: A: PDB Molecule:holliday junction dna helicase ruva; PDBTitle: ruva-ruvb complex 27 c2w9mB_ not modelled 96.7 27 PDB header:dna replication Chain: B: PDB Molecule:polymerase x; PDBTitle: structure of family x dna polymerase from deinococcus2 radiodurans 28 d1cuka2 not modelled 96.7 38 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:DNA helicase RuvA subunit, middle domain 29 d1ixra1 not modelled 96.5 37 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:DNA helicase RuvA subunit, middle domain 30 d1szpa1 not modelled 96.5 21 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:DNA repair protein Rad51, N-terminal domain 31 c1kdhA_ not modelled 96.4 17 PDB header:transferase/dna Chain: A: PDB Molecule:terminal deoxynucleotidyltransferase short PDBTitle: binary complex of murine terminal deoxynucleotidyl2 transferase with a primer single stranded dna 32 d1bvsa2 not modelled 96.3 32 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:DNA helicase RuvA subunit, middle domain 33 c2ihmA_ not modelled 96.3 27 PDB header:transferase/dna Chain: A: PDB Molecule:dna polymerase mu; PDBTitle: polymerase mu in ternary complex with gapped 11mer dna2 duplex and bound incoming nucleotide 34 d2aq0a1 not modelled 96.1 18 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Hef domain-like 35 c1hjpA_ not modelled 96.1 40 PDB header:dna recombination Chain: A: PDB Molecule:ruva; PDBTitle: holliday junction binding protein ruva from e. coli 36 c1d8lA_ not modelled 95.6 41 PDB header:gene regulation Chain: A: PDB Molecule:protein (holliday junction dna helicase ruva); PDBTitle: e. coli holliday junction binding protein ruva nh2 region2 lacking domain iii 37 c2bhnD_ not modelled 95.6 26 PDB header:hydrolase Chain: D: PDB Molecule:xpf endonuclease; PDBTitle: xpf from aeropyrum pernix 38 c2h5xA_ not modelled 95.6 33 PDB header:dna binding protein Chain: A: PDB Molecule:holliday junction atp-dependent dna helicase ruva; PDBTitle: ruva from mycobacterium tuberculosis 39 c1nomA_ not modelled 95.4 35 PDB header:nucleotidyltransferase Chain: A: PDB Molecule:dna polymerase beta; PDBTitle: dna polymerase beta (pol b) (e.c.2.7.7.7), 31-kd domain; soaked in the2 presence of mncl2 (5 millimolar) 40 c2nrzB_ not modelled 95.4 18 PDB header:hydrolase Chain: B: PDB Molecule:uvrabc system protein c; PDBTitle: crystal structure of the c-terminal half of uvrc bound to2 its catalytic divalent cation 41 c1b22A_ not modelled 95.2 18 PDB header:dna binding protein Chain: A: PDB Molecule:dna repair protein rad51; PDBTitle: rad51 (n-terminal domain) 42 d1b22a_ not modelled 95.2 18 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:DNA repair protein Rad51, N-terminal domain 43 c1rrqA_ not modelled 94.7 17 PDB header:hydrolase/dna Chain: A: PDB Molecule:muty; PDBTitle: muty adenine glycosylase in complex with dna containing an2 a:oxog pair 44 d2p6ra2 not modelled 94.1 23 Fold:Sec63 N-terminal domain-like Superfamily:Sec63 N-terminal domain-like Family:Achaeal helicase C-terminal domain 45 d1kg2a_ not modelled 94.1 26 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:Mismatch glycosylase 46 d1szpb1 not modelled 94.1 26 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:DNA repair protein Rad51, N-terminal domain 47 d1jmsa1 not modelled 94.0 16 Fold:SAM domain-like Superfamily:DNA polymerase beta, N-terminal domain-like Family:DNA polymerase beta, N-terminal domain-like 48 c1wg8B_ not modelled 93.9 36 PDB header:transferase Chain: B: PDB Molecule:predicted s-adenosylmethionine-dependent PDBTitle: crystal structure of a predicted s-adenosylmethionine-2 dependent methyltransferase tt1512 from thermus3 thermophilus hb8. 49 c2p6uA_ not modelled 93.9 23 PDB header:dna binding protein Chain: A: PDB Molecule:afuhel308 helicase; PDBTitle: apo structure of the hel308 superfamily 2 helicase 50 d1wg8a1 not modelled 93.5 36 Fold:SAM domain-like Superfamily:Putative methyltransferase TM0872, insert domain Family:Putative methyltransferase TM0872, insert domain 51 d3ci0k1 not modelled 93.1 17 Fold:SAM domain-like Superfamily:GspK insert domain-like Family:GspK insert domain-like 52 d2fmpa1 not modelled 92.9 20 Fold:SAM domain-like Superfamily:DNA polymerase beta, N-terminal domain-like Family:DNA polymerase beta, N-terminal domain-like 53 c2owoA_ not modelled 92.8 19 PDB header:ligase/dna Chain: A: PDB Molecule:dna ligase; PDBTitle: last stop on the road to repair: structure of e.coli dna ligase bound2 to nicked dna-adenylate 54 d1pu6a_ not modelled 92.8 24 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:3-Methyladenine DNA glycosylase III (MagIII) 55 c1dgsB_ not modelled 92.7 22 PDB header:ligase Chain: B: PDB Molecule:dna ligase; PDBTitle: crystal structure of nad+-dependent dna ligase from t.2 filiformis 56 c3n5nX_ not modelled 92.5 28 PDB header:hydrolase Chain: X: PDB Molecule:a/g-specific adenine dna glycosylase; PDBTitle: crystal structure analysis of the catalytic domain and interdomain2 connector of human muty homologue 57 c1v9pB_ not modelled 92.5 21 PDB header:ligase Chain: B: PDB Molecule:dna ligase; PDBTitle: crystal structure of nad+-dependent dna ligase 58 d1rrqa1 not modelled 92.0 19 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:Mismatch glycosylase 59 d2bcqa1 not modelled 91.6 22 Fold:SAM domain-like Superfamily:DNA polymerase beta, N-terminal domain-like Family:DNA polymerase beta, N-terminal domain-like 60 c2csdB_ not modelled 91.5 27 PDB header:isomerase Chain: B: PDB Molecule:topoisomerase v; PDBTitle: crystal structure of topoisomerase v (61 kda fragment) 61 c2kp7A_ not modelled 91.0 18 PDB header:hydrolase Chain: A: PDB Molecule:crossover junction endonuclease mus81; PDBTitle: solution nmr structure of the mus81 n-terminal hhh.2 northeast structural genomics consortium target mmt1a 62 d1mpga1 not modelled 90.7 26 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:DNA repair glycosylase, 2 C-terminal domains 63 d2abka_ not modelled 90.2 21 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:Endonuclease III 64 d1nzpa_ not modelled 90.2 22 Fold:SAM domain-like Superfamily:DNA polymerase beta, N-terminal domain-like Family:DNA polymerase beta, N-terminal domain-like 65 d1orna_ not modelled 89.7 25 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:Endonuclease III 66 c1vddC_ not modelled 89.2 33 PDB header:recombination Chain: C: PDB Molecule:recombination protein recr; PDBTitle: crystal structure of recombinational repair protein recr 67 d2fmpa2 not modelled 89.0 35 Fold:SAM domain-like Superfamily:PsbU/PolX domain-like Family:DNA polymerase beta-like, second domain 68 d1dk2a_ not modelled 89.0 20 Fold:SAM domain-like Superfamily:DNA polymerase beta, N-terminal domain-like Family:DNA polymerase beta, N-terminal domain-like 69 d1vdda_ not modelled 88.9 33 Fold:Recombination protein RecR Superfamily:Recombination protein RecR Family:Recombination protein RecR 70 d1keaa_ not modelled 88.2 17 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:Mismatch glycosylase 71 c1ut8B_ not modelled 88.0 31 PDB header:hydrolase Chain: B: PDB Molecule:exodeoxyribonuclease; PDBTitle: divalent metal ions (zinc) bound to t5 5'-exonuclease 72 d1a77a1 not modelled 87.5 33 Fold:SAM domain-like Superfamily:5' to 3' exonuclease, C-terminal subdomain Family:5' to 3' exonuclease, C-terminal subdomain 73 d2vana1 not modelled 87.4 38 Fold:SAM domain-like Superfamily:PsbU/PolX domain-like Family:DNA polymerase beta-like, second domain 74 d1rxwa1 not modelled 87.0 25 Fold:SAM domain-like Superfamily:5' to 3' exonuclease, C-terminal subdomain Family:5' to 3' exonuclease, C-terminal subdomain 75 c1mpgB_ not modelled 86.8 26 PDB header:hydrolase Chain: B: PDB Molecule:3-methyladenine dna glycosylase ii; PDBTitle: 3-methyladenine dna glycosylase ii from escherichia coli 76 c1rxvA_ not modelled 86.2 20 PDB header:hydrolase/dna Chain: A: PDB Molecule:flap structure-specific endonuclease; PDBTitle: crystal structure of a. fulgidus fen-1 bound to dna 77 c3n0uB_ not modelled 86.1 35 PDB header:hydrolase, lyase Chain: B: PDB Molecule:probable n-glycosylase/dna lyase; PDBTitle: crystal structure of tm1821, the 8-oxoguanine dna glycosylase of2 thermotoga maritima 78 d2bcqa2 not modelled 85.9 29 Fold:SAM domain-like Superfamily:PsbU/PolX domain-like Family:DNA polymerase beta-like, second domain 79 c3c1zA_ not modelled 85.2 23 PDB header:dna binding protein Chain: A: PDB Molecule:dna integrity scanning protein disa; PDBTitle: structure of the ligand-free form of a bacterial dna damage2 sensor protein 80 d1m6ya1 not modelled 85.1 35 Fold:SAM domain-like Superfamily:Putative methyltransferase TM0872, insert domain Family:Putative methyltransferase TM0872, insert domain 81 d1jmsa3 not modelled 84.8 23 Fold:SAM domain-like Superfamily:PsbU/PolX domain-like Family:DNA polymerase beta-like, second domain 82 d1ul1x1 not modelled 84.5 25 Fold:SAM domain-like Superfamily:5' to 3' exonuclease, C-terminal subdomain Family:5' to 3' exonuclease, C-terminal subdomain 83 d1cooa_ not modelled 83.9 26 Fold:SAM domain-like Superfamily:C-terminal domain of RNA polymerase alpha subunit Family:C-terminal domain of RNA polymerase alpha subunit 84 d1xo1a1 not modelled 83.8 33 Fold:SAM domain-like Superfamily:5' to 3' exonuclease, C-terminal subdomain Family:5' to 3' exonuclease, C-terminal subdomain 85 c3s6iA_ not modelled 82.5 30 PDB header:hydrolase/dna Chain: A: PDB Molecule:dna-3-methyladenine glycosylase 1; PDBTitle: schizosaccaromyces pombe 3-methyladenine dna glycosylase (mag1) in2 complex with abasic-dna. 86 d1lb2b_ not modelled 82.4 26 Fold:SAM domain-like Superfamily:C-terminal domain of RNA polymerase alpha subunit Family:C-terminal domain of RNA polymerase alpha subunit 87 d2a1ja1 not modelled 81.2 19 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Hef domain-like 88 d1z3eb1 not modelled 80.3 38 Fold:SAM domain-like Superfamily:C-terminal domain of RNA polymerase alpha subunit Family:C-terminal domain of RNA polymerase alpha subunit 89 d1doqa_ not modelled 79.6 33 Fold:SAM domain-like Superfamily:C-terminal domain of RNA polymerase alpha subunit Family:C-terminal domain of RNA polymerase alpha subunit 90 c2jhnB_ not modelled 79.6 33 PDB header:hydrolase Chain: B: PDB Molecule:3-methyladenine dna-glycosylase; PDBTitle: 3-methyladenine dna-glycosylase from archaeoglobus fulgidus 91 c2ziuA_ not modelled 79.3 35 PDB header:hydrolase Chain: A: PDB Molecule:mus81 protein; PDBTitle: crystal structure of the mus81-eme1 complex 92 d1ngna_ not modelled 79.2 16 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:Mismatch glycosylase 93 d1d8ba_ not modelled 76.9 4 Fold:SAM domain-like Superfamily:HRDC-like Family:HRDC domain from helicases 94 d1mc8a1 not modelled 76.5 35 Fold:SAM domain-like Superfamily:5' to 3' exonuclease, C-terminal subdomain Family:5' to 3' exonuclease, C-terminal subdomain 95 c3f10A_ not modelled 76.0 38 PDB header:hydrolase, lyase Chain: A: PDB Molecule:8-oxoguanine-dna-glycosylase; PDBTitle: crystal structure of clostridium acetobutylicum 8-2 oxoguanine dna glycosylase in complex with 8-oxoguanosine 96 d1b43a1 not modelled 75.0 42 Fold:SAM domain-like Superfamily:5' to 3' exonuclease, C-terminal subdomain Family:5' to 3' exonuclease, C-terminal subdomain 97 c1a77A_ not modelled 74.8 33 PDB header:5'-3' exo/endo nuclease Chain: A: PDB Molecule:flap endonuclease-1 protein; PDBTitle: flap endonuclease-1 from methanococcus jannaschii 98 d2noha1 not modelled 74.4 29 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:DNA repair glycosylase, 2 C-terminal domains 99 c3kntC_ not modelled 74.2 27 PDB header:hydrolase, lyase/dna Chain: C: PDB Molecule:n-glycosylase/dna lyase; PDBTitle: crystal structure of methanocaldococcus jannaschii 8-2 oxoguanine glycosylase/lyase in complex with 15mer dna3 containing 8-oxoguanine 100 d1u9la_ not modelled 73.6 25 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:NusA extra C-terminal domains 101 c2va8A_ not modelled 73.4 33 PDB header:hydrolase Chain: A: PDB Molecule:ski2-type helicase; PDBTitle: dna repair helicase hel308 102 c3fhgA_ not modelled 73.1 25 PDB header:dna repair, hydrolase, lyase Chain: A: PDB Molecule:n-glycosylase/dna lyase; PDBTitle: crystal structure of sulfolobus solfataricus 8-oxoguanine dna2 glycosylase (ssogg) 103 c1yqmA_ not modelled 72.8 30 PDB header:hydrolase/dna Chain: A: PDB Molecule:n-glycosylase/dna lyase; PDBTitle: catalytically inactive human 8-oxoguanine glycosylase2 crosslinked to 7-deazaguanine containing dna 104 c3q8lA_ not modelled 72.5 25 PDB header:hydrolase/dna Chain: A: PDB Molecule:flap endonuclease 1; PDBTitle: crystal structure of human flap endonuclease fen1 (wt) in complex with2 substrate 5'-flap dna, sm3+, and k+ 105 c1ko9A_ not modelled 72.2 33 PDB header:hydrolase Chain: A: PDB Molecule:8-oxoguanine dna glycosylase; PDBTitle: native structure of the human 8-oxoguanine dna glycosylase2 hogg1 106 c2yg8B_ not modelled 72.1 24 PDB header:hydrolase Chain: B: PDB Molecule:dna-3-methyladenine glycosidase ii, putative; PDBTitle: structure of an unusual 3-methyladenine dna glycosylase ii (2 alka) from deinococcus radiodurans 107 c1ul1Y_ not modelled 71.1 25 PDB header:hydrolase/dna binding protein Chain: Y: PDB Molecule:flap endonuclease-1; PDBTitle: crystal structure of the human fen1-pcna complex 108 c2h56C_ not modelled 69.8 21 PDB header:hydrolase Chain: C: PDB Molecule:dna-3-methyladenine glycosidase; PDBTitle: crystal structure of dna-3-methyladenine glycosidase (10174367) from2 bacillus halodurans at 2.55 a resolution 109 d2ve8a1 not modelled 69.7 23 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:FtsK C-terminal domain-like 110 c2izoA_ not modelled 65.1 21 PDB header:hydrolase Chain: A: PDB Molecule:flap structure-specific endonuclease; PDBTitle: structure of an archaeal pcna1-pcna2-fen1 complex 111 d2uubm1 not modelled 60.1 19 Fold:S13-like H2TH domain Superfamily:S13-like H2TH domain Family:Ribosomal protein S13 112 d1cmwa1 not modelled 60.0 30 Fold:SAM domain-like Superfamily:5' to 3' exonuclease, C-terminal subdomain Family:5' to 3' exonuclease, C-terminal subdomain 113 d2j5pa1 not modelled 57.9 27 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:FtsK C-terminal domain-like 114 c1b43A_ not modelled 54.0 41 PDB header:transferase Chain: A: PDB Molecule:protein (fen-1); PDBTitle: fen-1 from p. furiosus 115 d2gy9m1 not modelled 53.6 12 Fold:S13-like H2TH domain Superfamily:S13-like H2TH domain Family:Ribosomal protein S13 116 c3f52A_ not modelled 52.4 15 PDB header:transcription activator Chain: A: PDB Molecule:clp gene regulator (clgr); PDBTitle: crystal structure of the clp gene regulator clgr from c. glutamicum 117 d2e1fa1 not modelled 51.0 26 Fold:SAM domain-like Superfamily:HRDC-like Family:HRDC domain from helicases 118 d1wuda1 not modelled 50.8 25 Fold:SAM domain-like Superfamily:HRDC-like Family:HRDC domain from helicases 119 c2xznM_ not modelled 50.5 11 PDB header:ribosome Chain: M: PDB Molecule:rps18e; PDBTitle: crystal structure of the eukaryotic 40s ribosomal2 subunit in complex with initiation factor 1. this file3 contains the 40s subunit and initiation factor for4 molecule 2 120 c3rfaA_ not modelled 50.1 8 PDB header:oxidoreductase Chain: A: PDB Molecule:ribosomal rna large subunit methyltransferase n; PDBTitle: x-ray structure of rlmn from escherichia coli in complex with s-2 adenosylmethionine

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0