Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	T	V	T	V	K	D	L	V	I	G	T	G	A	P	K	I	I	V	S	L	M	A	K	D	I	A	S	V	K	S	E	A	L	A	Y	R	E	A	D	F	D	I	L	E	W	R	V	D	H	Y	A	D	L	S	N	V	E	S
Secondary structure
SS confidence
Disorder		?	?				?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	M	A	A	A	K	I	L	R	E	T	M	P	E	K	P	L	L	F	T	F	R	S	A	K	E	G	G	E	Q	A	I	S	T	E	A	Y	I	A	L	N	R	A	A	I	D	S	G	L	V	D	M	I	D	L	E	L	F	T	G
Secondary structure
SS confidence
Disorder																												?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		D	D	Q	V	K	E	T	V	A	Y	A	H	A	H	D	V	K	V	V	M	S	N	H	D	F	H	K	T	P	E	A	E	E	I	I	A	R	L	R	K	M	Q	S	F	D	A	D	I	P	K	I	A	L	M	P	Q	S	T	S	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		V	L	T	L	L	A	A	T	L	E	M	Q	E	Q	Y	A	D	R	P	I	I	T	M	S	M	A	K	T	G	V	I	S	R	L	A	G	E	V	F	G	S	A	A	T	F	G	A	V	K	K	A	S	A	P	G	Q	I	S	V	N
Secondary structure
SS confidence
Disorder																														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.
Sequence		D	L	R	T	V	L	T	I	L	H	Q	A
Secondary structure
SS confidence
Disorder											?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1gqn chain A Region: 1 - 252 Aligned: 252 Modelled: 252 Confidence: 100.0% Identity: 77% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 3js3 chain C Region: 1 - 252 Aligned: 252 Modelled: 252 Confidence: 100.0% Identity: 53% PDB header:lyase Chain: C: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: crystal structure of type i 3-dehydroquinate dehydratase (arod) from2 clostridium difficile with covalent reaction intermediate Phyre2 PDB 2yr1 chain B Region: 1 - 250 Aligned: 248 Modelled: 250 Confidence: 100.0% Identity: 39% PDB header:lyase Chain: B: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: crystal structure of 3-dehydroquinate dehydratase from geobacillus2 kaustophilus hta426 Phyre2 PDB 3l2i chain B Region: 1 - 251 Aligned: 245 Modelled: 251 Confidence: 100.0% Identity: 79% PDB header:lyase Chain: B: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: 1.85 angstrom crystal structure of the 3-dehydroquinate dehydratase2 (arod) from salmonella typhimurium lt2. Phyre2 PDB 2o7q chain A Region: 13 - 250 Aligned: 226 Modelled: 237 Confidence: 100.0% Identity: 30% PDB header:oxidoreductase,transferase Chain: A: PDB Molecule:bifunctional 3-dehydroquinate dehydratase/shikimate PDBTitle: crystal structure of the a. thaliana dhq-dehydroshikimate-sdh-2 shikimate-nadp(h) Phyre2 PDB 1sfl chain A Region: 17 - 249 Aligned: 226 Modelled: 233 Confidence: 100.0% Identity: 30% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 2ysw chain B Region: 17 - 251 Aligned: 217 Modelled: 235 Confidence: 100.0% Identity: 31% PDB header:lyase Chain: B: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: crystal structure of the 3-dehydroquinate dehydratase from aquifex2 aeolicus vf5 Phyre2 PDB 3l9c chain A Region: 15 - 251 Aligned: 218 Modelled: 237 Confidence: 100.0% Identity: 33% PDB header:lyase Chain: A: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: the crystal structure of smu.777 from streptococcus mutans ua159 Phyre2 PDB 2ocz chain A Region: 16 - 249 Aligned: 216 Modelled: 229 Confidence: 100.0% Identity: 28% PDB header:lyase Chain: A: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: the structure of a putative 3-dehydroquinate dehydratase from2 streptococcus pyogenes. Phyre2 PDB 2ox1 chain C Region: 17 - 250 Aligned: 195 Modelled: 217 Confidence: 100.0% Identity: 28% PDB header:lyase Chain: C: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: archaeal dehydroquinase Phyre2 PDB 2v82 chain A Region: 14 - 252 Aligned: 197 Modelled: 215 Confidence: 98.2% Identity: 14% PDB header:lyase Chain: A: PDB Molecule:2-dehydro-3-deoxy-6-phosphogalactonate aldolase; PDBTitle: kdpgal complexed to kdpgal Phyre2 PDB 1vhc chain A Region: 17 - 204 Aligned: 146 Modelled: 163 Confidence: 98.1% Identity: 16% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 1wbh chain A domain 1 Region: 16 - 204 Aligned: 147 Modelled: 169 Confidence: 98.0% Identity: 12% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 1mxs chain A Region: 17 - 204 Aligned: 146 Modelled: 163 Confidence: 98.0% Identity: 16% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 1wa3 chain A domain 1 Region: 17 - 204 Aligned: 144 Modelled: 173 Confidence: 97.8% Identity: 24% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 3f4w chain A Region: 17 - 204 Aligned: 165 Modelled: 179 Confidence: 97.7% Identity: 18% PDB header:synthase, lyase Chain: A: PDB Molecule:putative hexulose 6 phosphate synthase; PDBTitle: the 1.65a crystal structure of 3-hexulose-6-phosphate2 synthase from salmonella typhimurium Phyre2 PDB 2zdr chain A domain 2 Region: 2 - 251 Aligned: 227 Modelled: 234 Confidence: 97.7% Identity: 13% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: NeuB-like Phyre2 PDB 3lab chain A Region: 13 - 204 Aligned: 154 Modelled: 178 Confidence: 97.6% Identity: 17% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative kdpg (2-keto-3-deoxy-6-phosphogluconate) PDBTitle: crystal structure of a putative kdpg (2-keto-3-deoxy-6-2 phosphogluconate) aldolase from oleispira antarctica Phyre2 PDB 3pg8 chain B Region: 1 - 251 Aligned: 220 Modelled: 233 Confidence: 97.5% Identity: 11% PDB header:transferase Chain: B: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: truncated form of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase2 from thermotoga maritima Phyre2 PDB 3noy chain A Region: 2 - 216 Aligned: 189 Modelled: 202 Confidence: 97.5% Identity: 23% PDB header:oxidoreductase Chain: A: PDB Molecule:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; PDBTitle: crystal structure of ispg (gcpe) Phyre2 1 d1gqna_ 2 c3js3C_ 3 c2yr1B_ 4 c3l2iB_ 5 c2o7qA_ 6 d1sfla_ 7 c2yswB_ 8 c3l9cA_ 9 c2oczA_ 10 c2ox1C_ 11 c2v82A_ 12 d1vhca_ 13 d1wbha1 14 d1mxsa_ 15 d1wa3a1 16 c3f4wA_ 17 d2zdra2 18 c3labA_ 19 c3pg8B_ 20 c3noyA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1gqna_ 100.0 77 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 2 c3js3C_ 100.0 53 PDB header:lyase Chain: C: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: crystal structure of type i 3-dehydroquinate dehydratase (arod) from2 clostridium difficile with covalent reaction intermediate 3 c2yr1B_ 100.0 39 PDB header:lyase Chain: B: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: crystal structure of 3-dehydroquinate dehydratase from geobacillus2 kaustophilus hta426 4 c3l2iB_ 100.0 79 PDB header:lyase Chain: B: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: 1.85 angstrom crystal structure of the 3-dehydroquinate dehydratase2 (arod) from salmonella typhimurium lt2. 5 c2o7qA_ 100.0 30 PDB header:oxidoreductase,transferase Chain: A: PDB Molecule:bifunctional 3-dehydroquinate dehydratase/shikimate PDBTitle: crystal structure of the a. thaliana dhq-dehydroshikimate-sdh-2 shikimate-nadp(h) 6 d1sfla_ 100.0 30 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 7 c2yswB_ 100.0 31 PDB header:lyase Chain: B: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: crystal structure of the 3-dehydroquinate dehydratase from aquifex2 aeolicus vf5 8 c3l9cA_ 100.0 33 PDB header:lyase Chain: A: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: the crystal structure of smu.777 from streptococcus mutans ua159 9 c2oczA_ 100.0 28 PDB header:lyase Chain: A: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: the structure of a putative 3-dehydroquinate dehydratase from2 streptococcus pyogenes. 10 c2ox1C_ 100.0 28 PDB header:lyase Chain: C: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: archaeal dehydroquinase 11 c2v82A_ 98.2 14 PDB header:lyase Chain: A: PDB Molecule:2-dehydro-3-deoxy-6-phosphogalactonate aldolase; PDBTitle: kdpgal complexed to kdpgal 12 d1vhca_ 98.1 16 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 13 d1wbha1 98.0 12 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 14 d1mxsa_ 98.0 16 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 15 d1wa3a1 97.8 24 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 16 c3f4wA_ 97.7 18 PDB header:synthase, lyase Chain: A: PDB Molecule:putative hexulose 6 phosphate synthase; PDBTitle: the 1.65a crystal structure of 3-hexulose-6-phosphate2 synthase from salmonella typhimurium 17 d2zdra2 97.7 13 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like 18 c3labA_ 97.6 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative kdpg (2-keto-3-deoxy-6-phosphogluconate) PDBTitle: crystal structure of a putative kdpg (2-keto-3-deoxy-6-2 phosphogluconate) aldolase from oleispira antarctica 19 c3pg8B_ 97.5 11 PDB header:transferase Chain: B: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: truncated form of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase2 from thermotoga maritima 20 c3noyA_ 97.5 23 PDB header:oxidoreductase Chain: A: PDB Molecule:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; PDBTitle: crystal structure of ispg (gcpe) 21 d1ajza_ not modelled 97.5 17 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 22 c3k13A_ not modelled 97.5 14 PDB header:transferase Chain: A: PDB Molecule:5-methyltetrahydrofolate-homocysteine methyltransferase; PDBTitle: structure of the pterin-binding domain metr of 5-2 methyltetrahydrofolate-homocysteine methyltransferase from3 bacteroides thetaiotaomicron 23 c1tx2A_ not modelled 97.5 13 PDB header:transferase Chain: A: PDB Molecule:dhps, dihydropteroate synthase; PDBTitle: dihydropteroate synthetase, with bound inhibitor manic, from bacillus2 anthracis 24 d1tx2a_ not modelled 97.5 13 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 25 c1xuzA_ not modelled 97.5 13 PDB header:biosynthetic protein Chain: A: PDB Molecule:polysialic acid capsule biosynthesis protein siac; PDBTitle: crystal structure analysis of sialic acid synthase (neub)from2 neisseria meningitidis, bound to mn2+, phosphoenolpyruvate, and n-3 acetyl mannosaminitol 26 d3bofa1 not modelled 97.4 14 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Methyltetrahydrofolate-utiluzing methyltransferases 27 c2y5sA_ not modelled 97.4 18 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase; PDBTitle: crystal structure of burkholderia cenocepacia dihydropteroate2 synthase complexed with 7,8-dihydropteroate. 28 c1rr2A_ not modelled 97.4 13 PDB header:transferase Chain: A: PDB Molecule:transcarboxylase 5s subunit; PDBTitle: propionibacterium shermanii transcarboxylase 5s subunit bound to 2-2 ketobutyric acid 29 c3ivuB_ not modelled 97.3 15 PDB header:transferase Chain: B: PDB Molecule:homocitrate synthase, mitochondrial; PDBTitle: homocitrate synthase lys4 bound to 2-og 30 d1ad1a_ not modelled 97.3 17 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 31 d1h1ya_ not modelled 97.2 15 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 32 c2y0fD_ not modelled 97.2 18 PDB header:oxidoreductase Chain: D: PDB Molecule:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; PDBTitle: structure of gcpe (ispg) from thermus thermophilus hb27 33 d1f6ya_ not modelled 97.1 13 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Methyltetrahydrofolate-utiluzing methyltransferases 34 c2yw3E_ not modelled 97.0 20 PDB header:lyase Chain: E: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase/2-deydro-3- PDBTitle: crystal structure analysis of the 4-hydroxy-2-oxoglutarate aldolase/2-2 deydro-3-deoxyphosphogluconate aldolase from tthb1 35 c3nvtA_ not modelled 96.9 15 PDB header:transferase/isomerase Chain: A: PDB Molecule:3-deoxy-d-arabino-heptulosonate 7-phosphate synthase; PDBTitle: 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7-2 phosphoheptulonate synthase/chorismate mutase (aroa) from listeria3 monocytogenes egd-e 36 d1tqja_ not modelled 96.9 13 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 37 c2dzaA_ not modelled 96.9 20 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase; PDBTitle: crystal structure of dihydropteroate synthase from thermus2 thermophilus hb8 in complex with 4-aminobenzoate 38 c3ewbX_ not modelled 96.8 17 PDB header:transferase Chain: X: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of n-terminal domain of putative 2-2 isopropylmalate synthase from listeria monocytogenes 39 c2nx9B_ not modelled 96.8 13 PDB header:lyase Chain: B: PDB Molecule:oxaloacetate decarboxylase 2, subunit alpha; PDBTitle: crystal structure of the carboxyltransferase domain of the2 oxaloacetate decarboxylase na+ pump from vibrio cholerae 40 d1xi3a_ not modelled 96.7 14 Fold:TIM beta/alpha-barrel Superfamily:Thiamin phosphate synthase Family:Thiamin phosphate synthase 41 c2yciX_ not modelled 96.6 12 PDB header:transferase Chain: X: PDB Molecule:5-methyltetrahydrofolate corrinoid/iron sulfur protein PDBTitle: methyltransferase native 42 c3tr9A_ not modelled 96.6 18 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase; PDBTitle: structure of a dihydropteroate synthase (folp) in complex with pteroic2 acid from coxiella burnetii 43 c3qc3B_ not modelled 96.6 16 PDB header:isomerase Chain: B: PDB Molecule:d-ribulose-5-phosphate-3-epimerase; PDBTitle: crystal structure of a d-ribulose-5-phosphate-3-epimerase (np_954699)2 from homo sapiens at 2.20 a resolution 44 d1vyra_ not modelled 96.6 14 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 45 d1pkla2 not modelled 96.6 17 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 46 d1xcfa_ not modelled 96.5 15 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 47 c2h90A_ not modelled 96.5 18 PDB header:oxidoreductase Chain: A: PDB Molecule:xenobiotic reductase a; PDBTitle: xenobiotic reductase a in complex with coumarin 48 d1q6oa_ not modelled 96.4 18 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase 49 c3exsB_ not modelled 96.4 12 PDB header:lyase Chain: B: PDB Molecule:rmpd (hexulose-6-phosphate synthase); PDBTitle: crystal structure of kgpdc from streptococcus mutans in2 complex with d-r5p 50 c2vp8A_ not modelled 96.3 16 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase 2; PDBTitle: structure of mycobacterium tuberculosis rv1207 51 d1qopa_ not modelled 96.3 13 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 52 c3khdC_ not modelled 96.2 18 PDB header:transferase Chain: C: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure of pff1300w. 53 c3inpA_ not modelled 96.2 12 PDB header:isomerase Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase; PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis. 54 c2zq0B_ not modelled 96.2 18 PDB header:hydrolase Chain: B: PDB Molecule:alpha-glucosidase (alpha-glucosidase susb); PDBTitle: crystal structure of susb complexed with acarbose 55 c2vefB_ not modelled 96.2 20 PDB header:transferase Chain: B: PDB Molecule:dihydropteroate synthase; PDBTitle: dihydropteroate synthase from streptococcus pneumoniae 56 d1liua2 not modelled 96.2 17 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 57 c3b0vD_ not modelled 96.1 20 PDB header:oxidoreductase/rna Chain: D: PDB Molecule:trna-dihydrouridine synthase; PDBTitle: trna-dihydrouridine synthase from thermus thermophilus in complex with2 trna 58 d1rpxa_ not modelled 96.1 14 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 59 c3a24A_ not modelled 96.0 18 PDB header:hydrolase Chain: A: PDB Molecule:alpha-galactosidase; PDBTitle: crystal structure of bt1871 retaining glycosidase 60 c3ct7E_ not modelled 95.9 22 PDB header:isomerase Chain: E: PDB Molecule:d-allulose-6-phosphate 3-epimerase; PDBTitle: crystal structure of d-allulose 6-phosphate 3-epimerase2 from escherichia coli k-12 61 d1dvja_ not modelled 95.9 17 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase 62 d1a3xa2 not modelled 95.8 21 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 63 d1vhna_ not modelled 95.7 11 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 64 d1tqxa_ not modelled 95.7 11 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 65 d2flia1 not modelled 95.7 15 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 66 d1yx1a1 not modelled 95.7 15 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:KguE-like 67 d1rd5a_ not modelled 95.6 11 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 68 c1nvmG_ not modelled 95.5 15 PDB header:lyase/oxidoreductase Chain: G: PDB Molecule:4-hydroxy-2-oxovalerate aldolase; PDBTitle: crystal structure of a bifunctional aldolase-dehydrogenase :2 sequestering a reactive and volatile intermediate 69 d1km4a_ not modelled 95.5 17 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase 70 d2g50a2 not modelled 95.4 15 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 71 d1vr6a1 not modelled 95.3 10 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 72 c1ps9A_ not modelled 95.3 22 PDB header:oxidoreductase Chain: A: PDB Molecule:2,4-dienoyl-coa reductase; PDBTitle: the crystal structure and reaction mechanism of e. coli 2,4-2 dienoyl coa reductase 73 c2ekcA_ not modelled 95.3 16 PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5 74 c3thaB_ not modelled 95.2 13 PDB header:lyase Chain: B: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: tryptophan synthase subunit alpha from campylobacter jejuni. 75 d1vlia2 not modelled 95.0 11 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like 76 c3hf3A_ not modelled 95.0 30 PDB header:oxidoreductase Chain: A: PDB Molecule:chromate reductase; PDBTitle: old yellow enzyme from thermus scotoductus sa-01 77 d1yxya1 not modelled 94.9 13 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:NanE-like 78 c3sz8D_ not modelled 94.9 12 PDB header:transferase Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 2; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia pseudomallei 79 d1gwja_ not modelled 94.9 17 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 80 c1vs1B_ not modelled 94.8 15 PDB header:transferase Chain: B: PDB Molecule:3-deoxy-7-phosphoheptulonate synthase; PDBTitle: crystal structure of 3-deoxy-d-arabino-heptulosonate-7-2 phosphate synthase (dahp synthase) from aeropyrum pernix3 in complex with mn2+ and pep 81 c3gr7A_ not modelled 94.8 16 PDB header:oxidoreductase Chain: A: PDB Molecule:nadph dehydrogenase; PDBTitle: structure of oye from geobacillus kaustophilus, hexagonal2 crystal form 82 d1djqa1 not modelled 94.8 23 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 83 c3jr2D_ not modelled 94.7 17 PDB header:biosynthetic protein Chain: D: PDB Molecule:hexulose-6-phosphate synthase sgbh; PDBTitle: x-ray crystal structure of the mg-bound 3-keto-l-gulonate-6-phosphate2 decarboxylase from vibrio cholerae o1 biovar el tor str. n16961 84 c1djnB_ not modelled 94.7 20 PDB header:oxidoreductase Chain: B: PDB Molecule:trimethylamine dehydrogenase; PDBTitle: structural and biochemical characterization of recombinant wild type2 trimethylamine dehydrogenase from methylophilus methylotrophus (sp.3 w3a1) 85 c3ajxA_ not modelled 94.6 17 PDB header:lyase Chain: A: PDB Molecule:3-hexulose-6-phosphate synthase; PDBTitle: crystal structure of 3-hexulose-6-phosphate synthase 86 c2zyfA_ not modelled 94.4 16 PDB header:transferase Chain: A: PDB Molecule:homocitrate synthase; PDBTitle: crystal structure of homocitrate synthase from thermus thermophilus2 complexed with magnesuim ion and alpha-ketoglutarate 87 c3dx5A_ not modelled 94.3 15 PDB header:lyase Chain: A: PDB Molecule:uncharacterized protein asbf; PDBTitle: crystal structure of the probable 3-dhs dehydratase asbf involved in2 the petrobactin synthesis from bacillus anthracis 88 c1yadD_ not modelled 94.3 14 PDB header:transcription Chain: D: PDB Molecule:regulatory protein teni; PDBTitle: structure of teni from bacillus subtilis 89 c2ftpA_ not modelled 94.3 16 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa 90 c2h9aA_ not modelled 93.8 13 PDB header:oxidoreductase Chain: A: PDB Molecule:carbon monoxide dehydrogenase corrinoid/iron- PDBTitle: corrinoid iron-sulfur protein 91 d1geha1 not modelled 93.8 17 Fold:TIM beta/alpha-barrel Superfamily:RuBisCo, C-terminal domain Family:RuBisCo, large subunit, C-terminal domain 92 d1ps9a1 not modelled 93.8 17 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 93 d2d69a1 not modelled 93.7 18 Fold:TIM beta/alpha-barrel Superfamily:RuBisCo, C-terminal domain Family:RuBisCo, large subunit, C-terminal domain 94 c3bolB_ not modelled 93.6 10 PDB header:transferase Chain: B: PDB Molecule:5-methyltetrahydrofolate s-homocysteine PDBTitle: cobalamin-dependent methionine synthase (1-566) from2 thermotoga maritima complexed with zn2+ 95 d1icpa_ not modelled 93.6 12 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 96 c2c3zA_ not modelled 93.5 18 PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus 97 c3iwpK_ not modelled 93.2 15 PDB header:metal binding protein Chain: K: PDB Molecule:copper homeostasis protein cutc homolog; PDBTitle: crystal structure of human copper homeostasis protein cutc 98 d1eyea_ not modelled 93.2 19 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 99 c3bg5C_ not modelled 93.1 13 PDB header:ligase Chain: C: PDB Molecule:pyruvate carboxylase; PDBTitle: crystal structure of staphylococcus aureus pyruvate2 carboxylase 100 c3gkaB_ not modelled 93.1 14 PDB header:oxidoreductase Chain: B: PDB Molecule:n-ethylmaleimide reductase; PDBTitle: crystal structure of n-ethylmaleimidine reductase from2 burkholderia pseudomallei 101 c3bsmD_ not modelled 92.4 9 PDB header:lyase Chain: D: PDB Molecule:mandelate racemase/muconate lactonizing enzyme; PDBTitle: crystal structure of d-mannonate dehydratase from2 chromohalobacter salexigens 102 c3kruC_ not modelled 92.4 21 PDB header:oxidoreductase Chain: C: PDB Molecule:nadh:flavin oxidoreductase/nadh oxidase; PDBTitle: crystal structure of the thermostable old yellow enzyme from2 thermoanaerobacter pseudethanolicus e39 103 c1zfjA_ not modelled 92.3 21 PDB header:oxidoreductase Chain: A: PDB Molecule:inosine monophosphate dehydrogenase; PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes 104 c3navB_ not modelled 92.2 14 PDB header:lyase Chain: B: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961 105 c3nwrA_ not modelled 91.7 18 PDB header:lyase Chain: A: PDB Molecule:a rubisco-like protein; PDBTitle: crystal structure of a rubisco-like protein from burkholderia fungorum 106 d1twda_ not modelled 91.7 14 Fold:TIM beta/alpha-barrel Superfamily:CutC-like Family:CutC-like 107 d1s2wa_ not modelled 91.6 17 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 108 c3bg3B_ not modelled 91.6 14 PDB header:ligase Chain: B: PDB Molecule:pyruvate carboxylase, mitochondrial; PDBTitle: crystal structure of human pyruvate carboxylase (missing2 the biotin carboxylase domain at the n-terminus) 109 c3l5aA_ not modelled 91.6 25 PDB header:oxidoreductase Chain: A: PDB Molecule:nadh/flavin oxidoreductase/nadh oxidase; PDBTitle: crystal structure of a probable nadh-dependent flavin oxidoreductase2 from staphylococcus aureus 110 c3atyA_ not modelled 91.5 12 PDB header:oxidoreductase Chain: A: PDB Molecule:prostaglandin f2a synthase; PDBTitle: crystal structure of tcoye 111 d1nvma2 not modelled 91.5 15 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:HMGL-like 112 d2q02a1 not modelled 91.3 12 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:IolI-like 113 d2tpsa_ not modelled 91.2 14 Fold:TIM beta/alpha-barrel Superfamily:Thiamin phosphate synthase Family:Thiamin phosphate synthase 114 c2oemA_ not modelled 90.8 13 PDB header:isomerase Chain: A: PDB Molecule:2,3-diketo-5-methylthiopentyl-1-phosphate enolase; PDBTitle: crystal structure of a rubisco-like protein from geobacillus2 kaustophilus liganded with mg2+ and 2,3-diketohexane 1-phosphate 115 c3igsB_ not modelled 90.6 17 PDB header:isomerase Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2; PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase 116 c2bdqA_ not modelled 89.8 12 PDB header:metal transport Chain: A: PDB Molecule:copper homeostasis protein cutc; PDBTitle: crystal structure of the putative copper homeostasis2 protein cutc from streptococcus agalactiae, northeast3 strucural genomics target sar15. 117 c2gq8A_ not modelled 89.7 20 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase, fmn-binding; PDBTitle: structure of sye1, an oye homologue from s. ondeidensis, in complex2 with p-hydroxyacetophenone 118 d8ruca1 not modelled 89.7 19 Fold:TIM beta/alpha-barrel Superfamily:RuBisCo, C-terminal domain Family:RuBisCo, large subunit, C-terminal domain 119 c3t4cD_ not modelled 89.7 14 PDB header:transferase Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 1; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia ambifaria 120 c3gndC_ not modelled 89.6 9 PDB header:lyase Chain: C: PDB Molecule:aldolase lsrf; PDBTitle: crystal structure of e. coli lsrf in complex with ribulose-5-phosphate

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0