PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: d2tpsa_

Fold library id	Fold	Superfamily	Family
d2tpsa_	TIM beta/alpha-barrel	Thiamin phosphate synthase	Thiamin phosphate synthase

Links to external resources
Added to library: Tue Mar 16 13:53:18 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence H G I R M T R I S R E M M K E L L S V Y F I M G S N N T K A D P V T V V Q K A L K G G A T L Y Q F R E K G G D A L T G E A R I K F A E K A Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
T T
G G G
S S
T
S
S T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence A A C R E A G V P F I V N D D V E L A L N L K A D G I H I G Q E D A N A K E V R A A I G D M I L G V S A H T M S E V K Q A E E D G A D Y V G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S
T
S
T T S S
T T S
S T
S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence L G P I Y P T E T K K D T R A V Q G V S L I E A V R R Q G I S I P I V G I G G I T I D N A A P V I Q A G A D G V S M I S A I S Q A E D P E S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
S S S S
T T T T
S S
T T T S T T
S S T S S

. . . . . . . . . 220 . . . . . .

Sequence A A R K F R E E I Q T Y K T G R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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Phyre2 is part of Genome3D

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	H	G	I	R	M	T	R	I	S	R	E	M	M	K	E	L	L	S	V	Y	F	I	M	G	S	N	N	T	K	A	D	P	V	T	V	V	Q	K	A	L	K	G	G	A	T	L	Y	Q	F	R	E	K	G	G	D	A	L	T	G	E	A	R	I	K	F	A	E	K	A	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					S	S											T	T							G	G	G		S	S													T		S								S	T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	A	A	C	R	E	A	G	V	P	F	I	V	N	D	D	V	E	L	A	L	N	L	K	A	D	G	I	H	I	G	Q	E	D	A	N	A	K	E	V	R	A	A	I	G	D	M	I	L	G	V	S	A	H	T	M	S	E	V	K	Q	A	E	E	D	G	A	D	Y	V	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							T							S									T		S						T	T	S	S										T	T	S								S											T		S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	L	G	P	I	Y	P	T	E	T	K	K	D	T	R	A	V	Q	G	V	S	L	I	E	A	V	R	R	Q	G	I	S	I	P	I	V	G	I	G	G	I	T	I	D	N	A	A	P	V	I	Q	A	G	A	D	G	V	S	M	I	S	A	I	S	Q	A	E	D	P	E	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S	S				S	S	S	S						T	T									T	T									S	S			T	T	T	S						T	T		S					S					T	S	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.
Sequence	A	A	R	K	F	R	E	E	I	Q	T	Y	K	T	G	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)